Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C008 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP02359 | Heme oxygenase 1 (HMOX1) | 25.3 | ||||
| LDTP03540 | Heme oxygenase 2 (HMOX2) | 16.0 | ||||
| LDTP00832 | NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) | 11.3 | ||||
| LDTP09874 | Endoplasmic reticulum protein SC65 (P3H4) | 8.1 | ||||
| LDTP04004 | Lysosomal Pro-X carboxypeptidase (PRCP) | 6.4 | ||||
| LDTP13751 | Exonuclease 1 (EXO1) | 6.3 | ||||
| LDTP06227 | Prostaglandin reductase 1 (PTGR1) | 6.0 | ||||
| LDTP04388 | Palmitoyl-protein thioesterase 1 (PPT1) | 5.9 | ||||
| LDTP15988 | Probable serine carboxypeptidase CPVL (CPVL) | 5.9 | ||||
| LDTP16032 | Retinoid-inducible serine carboxypeptidase (SCPEP1) | 5.4 | ||||
| LDTP01687 | Apoptosis-inducing factor 1, mitochondrial (AIFM1) | 5.3 | ||||
| LDTP13282 | Prenylcysteine oxidase 1 (PCYOX1) | 5.2 | ||||
| LDTP03417 | Proteasome subunit beta type-4 (PSMB4) | 5.2 | ||||
| LDTP13189 | Cytochrome b-c1 complex subunit 9 (UQCR10) | 5.0 | ||||
| LDTP02837 | Beta-galactosidase (GLB1) | 4.9 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP03277 | ER lumen protein-retaining receptor 1 (KDELR1) | 14.7 | ||||
| LDTP06034 | Lysosome membrane protein 2 (SCARB2) | 11.3 | ||||
| LDTP06221 | StAR-related lipid transfer protein 3 (STARD3) | 10.7 | ||||
| LDTP06945 | Sigma intracellular receptor 2 (TMEM97) | 9.9 | ||||
| LDTP01059 | Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) | 9.7 | ||||
| LDTP06426 | Translocating chain-associated membrane protein 1 (TRAM1) | 8.3 | ||||
| LDTP10913 | Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) | 8.2 | ||||
| LDTP03132 | Voltage-dependent anion-selective channel protein 1 (VDAC1) | 8.0 | ||||
| LDTP07236 | Protein GPR107 (GPR107) | 7.6 | ||||
| LDTP04033 | Translocon-associated protein subunit alpha (SSR1) | 7.1 | ||||
| LDTP13174 | Mitochondrial dicarboxylate carrier (SLC25A10) | 7.1 | ||||
| LDTP04071 | Voltage-dependent anion-selective channel protein 2 (VDAC2) | 6.7 | ||||
| LDTP12383 | Protein GPR108 (GPR108) | 6.6 | ||||
| LDTP07885 | Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) | 6.3 | ||||
| LDTP10958 | Sigma non-opioid intracellular receptor 1 (SIGMAR1) | 5.8 | ||||
| LDTP07462 | MFS-type transporter SLC18B1 (SLC18B1) | 5.5 | ||||
| LDTP16813 | Tetraspanin-3 (TSPAN3) | 5.5 | ||||
Transcription factor
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP16717 | Forkhead-associated domain-containing protein 1 (FHAD1) | 10.1 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP03678 | ER lumen protein-retaining receptor 2 (KDELR2) | 12.3 | ||||
| LDTP12565 | Mitochondrial import receptor subunit TOM22 homolog (TOMM22) | 12.0 | ||||
| LDTP11076 | Apolipoprotein L2 (APOL2) | 9.9 | ||||
| LDTP13606 | Mammalian ependymin-related protein 1 (EPDR1) | 7.8 | ||||
| LDTP05160 | Nucleobindin-2 (NUCB2) | 7.7 | ||||
| LDTP14458 | Tetraspanin-6 (TSPAN6) | 6.3 | ||||
| LDTP04094 | Large proline-rich protein BAG6 (BAG6) | 5.6 | ||||
| LDTP14172 | Sorting nexin-9 (SNX9) | 5.6 | ||||
| LDTP07906 | Mediator of RNA polymerase II transcription subunit 25 (MED25) | 5.4 | ||||
| LDTP15253 | HEAT repeat-containing protein 3 (HEATR3) | 5.2 | ||||
| LDTP16080 | Protein FAM114A2 (FAM114A2) | 5.2 | ||||