General Information of Experiment

Probe Name C083  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 8 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP14218  Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) 10.1
 LDTP16007  Lipid droplet-associated hydrolase (LDAH) 10.0
 LDTP04246  Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) 8.6
 LDTP10032  7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) 8.0
 LDTP15484  Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) 6.6
 LDTP12363  Lysophosphatidic acid phosphatase type 6 (ACP6) 5.7
 LDTP02175  Epoxide hydrolase 1 (EPHX1) 5.7
 LDTP03540  Heme oxygenase 2 (HMOX2) 5.1
Transporter and channel
Click to Show/Hide to Show 7 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP14970  Metaxin-3 (MTX3) 9.9
 LDTP01804  ATP synthase subunit a (MT-ATP6) 7.9
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 7.8
 LDTP16201  B-cell receptor-associated protein 29 (BCAP29) 7.8
 LDTP10913  Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) 7.2
 LDTP01059  Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) 5.8
 LDTP08881  Transmembrane protein 199 (TMEM199) 5.1
Other
Click to Show/Hide to Show 5 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP13755  Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) 8.2
 LDTP03678  ER lumen protein-retaining receptor 2 (KDELR2) 6.4
 LDTP14058  Rap guanine nucleotide exchange factor 2 (RAPGEF2) 6.4
 LDTP08248  NLR family member X1 (NLRX1) 5.4
 LDTP07906  Mediator of RNA polymerase II transcription subunit 25 (MED25) 5.2

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587