Details of the Probe

General Information of Probe

Probe ID
LDPC0634
Probe Name
C419
Synonyms
Z3433405643
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 331.8
Lipid-water partition coefficient (xlogp) 3
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C17H18ClN3O2
IUPAC Name
N-[2-(3-but-3-ynyldiazirin-3-yl)ethyl]-2-(5-chloro-2,3-dihydro-1-benzofuran-7-yl)acetamide
Canonical SMILES
C#CCCC1(N=N1)CCNC(=O)CC2=CC(=CC3=C2OCC3)Cl
InChI
InChI=1S/C17H18ClN3O2/c1-2-3-5-17(20-21-17)6-7-19-15(22)11-13-10-14(18)9-12-4-8-23-16(12)13/h1,9-10H,3-8,11H2,(H,19,22)
InChIKey
JKLAOGPIXSKUSM-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

154 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
7-dehydrocholesterol reductase (DHCR7) LDTP13131 10.48  LDD2074 
7-dehydrocholesterol reductase (DHCR7) LDTP13131 10.48  LDD2074 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 14.42  LDD2074 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 14.42  LDD2074 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 54.57  LDD2074 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 54.57  LDD2074 
Acid ceramidase (ASAH1) LDTP05905 20.11  LDD2074 
Acid ceramidase (ASAH1) LDTP05905 20.11  LDD2074 
Alpha-galactosidase A (GLA) LDTP02141 13.36  LDD2074 
Alpha-galactosidase A (GLA) LDTP02141 13.36  LDD2074 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 16.22  LDD2074 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 16.22  LDD2074 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 18.90  LDD2074 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 18.90  LDD2074 
Beta-galactosidase (GLB1) LDTP02837 25.63  LDD2074 
Beta-galactosidase (GLB1) LDTP02837 25.63  LDD2074 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 17.63  LDD2074 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 17.63  LDD2074 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 18.25  LDD2074 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 18.25  LDD2074 
Choline kinase alpha (CHKA) LDTP03787 18.90  LDD2074 
Choline kinase alpha (CHKA) LDTP03787 18.90  LDD2074 
COP9 signalosome complex subunit 4 (COPS4) LDTP11187 10.78  LDD2074 
COP9 signalosome complex subunit 4 (COPS4) LDTP11187 10.78  LDD2074 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 12.30  LDD2074 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 12.30  LDD2074 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 14.52  LDD2074 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 14.52  LDD2074 
Cytochrome b5 type B (CYB5B) LDTP00697 65.80  LDD2074 
Cytochrome b5 type B (CYB5B) LDTP00697 65.80  LDD2074 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 16.45  LDD2074 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 16.45  LDD2074 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 9.19  LDD2074 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 9.19  LDD2074 
Delta(24)-sterol reductase (DHCR24) LDTP06375 11.00  LDD2074 
Delta(24)-sterol reductase (DHCR24) LDTP06375 11.00  LDD2074 
Deoxyhypusine hydroxylase (DOHH) LDTP11225 10.85  LDD2074 
Deoxyhypusine hydroxylase (DOHH) LDTP11225 10.85  LDD2074 
DNA replication licensing factor MCM4 (MCM4) LDTP03680 32.22  LDD2074 
DNA replication licensing factor MCM4 (MCM4) LDTP03680 32.22  LDD2074 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 9.19  LDD2074 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 9.19  LDD2074 
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (ALG12) LDTP11259 8.88  LDD2074 
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (ALG12) LDTP11259 8.88  LDD2074 
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) LDTP10699 13.83  LDD2074 
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) LDTP10699 13.83  LDD2074 
E3 ubiquitin-protein ligase UBR1 (UBR1) LDTP08564 10.85  LDD2074 
E3 ubiquitin-protein ligase UBR1 (UBR1) LDTP08564 10.85  LDD2074 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 13.83  LDD2074 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 13.83  LDD2074 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 19.97  LDD2074 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 19.97  LDD2074 
Glyoxalase domain-containing protein 4 (GLOD4) LDTP16040 12.04  LDD2074 
Glyoxalase domain-containing protein 4 (GLOD4) LDTP16040 12.04  LDD2074 
Heme oxygenase 1 (HMOX1) LDTP02359 14.72  LDD2074 
Heme oxygenase 1 (HMOX1) LDTP02359 14.72  LDD2074 
Heme oxygenase 2 (HMOX2) LDTP03540 30.27  LDD2074 
Heme oxygenase 2 (HMOX2) LDTP03540 30.27  LDD2074 
Histone-lysine N-methyltransferase 2A (KMT2A) LDTP05396 22.47  LDD2074 
Histone-lysine N-methyltransferase 2A (KMT2A) LDTP05396 22.47  LDD2074 
Histone-lysine N-methyltransferase NSD2 (NSD2) LDTP01759 11.96  LDD2074 
Histone-lysine N-methyltransferase NSD2 (NSD2) LDTP01759 11.96  LDD2074 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 21.11  LDD2074 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 21.11  LDD2074 
Isochorismatase domain-containing protein 1 (ISOC1) LDTP19851 46.85  LDD2074 
Isochorismatase domain-containing protein 1 (ISOC1) LDTP19851 46.85  LDD2074 
Kinesin-like protein KIF18B (KIF18B) LDTP08390 17.75  LDD2074 
Kinesin-like protein KIF18B (KIF18B) LDTP08390 17.75  LDD2074 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 11.08  LDD2074 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 11.08  LDD2074 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 37.27  LDD2074 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 37.27  LDD2074 
Lysine-specific histone demethylase 2 (KDM1B) LDTP09043 9.00  LDD2074 
Lysine-specific histone demethylase 2 (KDM1B) LDTP09043 9.00  LDD2074 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 63.12  LDD2074 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 63.12  LDD2074 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 13.45  LDD2074 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 13.45  LDD2074 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 11.55  LDD2074 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 11.55  LDD2074 
Lysosomal acid phosphatase (ACP2) LDTP02539 17.75  LDD2074 
Lysosomal acid phosphatase (ACP2) LDTP02539 17.75  LDD2074 
Lysosomal alpha-glucosidase (GAA) LDTP02486 8.94  LDD2074 
Lysosomal alpha-glucosidase (GAA) LDTP02486 8.94  LDD2074 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 27.47  LDD2074 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 27.47  LDD2074 
Lysosomal protective protein (CTSA) LDTP02505 16.91  LDD2074 
Lysosomal protective protein (CTSA) LDTP02505 16.91  LDD2074 
Minor histocompatibility antigen H13 (HM13) LDTP09396 9.78  LDD2074 
Minor histocompatibility antigen H13 (HM13) LDTP09396 9.78  LDD2074 
N-alpha-acetyltransferase 40 (NAA40) LDTP08265 37.01  LDD2074 
N-alpha-acetyltransferase 40 (NAA40) LDTP08265 37.01  LDD2074 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 13.64  LDD2074 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 13.64  LDD2074 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 22.32  LDD2074 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 22.32  LDD2074 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 11.63  LDD2074 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 11.63  LDD2074 
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) LDTP01743 12.04  LDD2074 
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) LDTP01743 12.04  LDD2074 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 27.67  LDD2074 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 27.67  LDD2074 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 11.63  LDD2074 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 11.63  LDD2074 
NADH-ubiquinone oxidoreductase chain 2 (MT-ND2) LDTP01983 35.51  LDD2074 
NADH-ubiquinone oxidoreductase chain 2 (MT-ND2) LDTP01983 35.51  LDD2074 
Obg-like ATPase 1 (OLA1) LDTP12610 10.85  LDD2074 
Obg-like ATPase 1 (OLA1) LDTP12610 10.85  LDD2074 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 32.45  LDD2074 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 32.45  LDD2074 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 11.24  LDD2074 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 11.24  LDD2074 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 15.56  LDD2074 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 15.56  LDD2074 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 11.00  LDD2074 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 11.00  LDD2074 
Phosphatidylserine synthase 1 (PTDSS1) LDTP04203 11.96  LDD2074 
Phosphatidylserine synthase 1 (PTDSS1) LDTP04203 11.96  LDD2074 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 23.43  LDD2074 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 23.43  LDD2074 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 32.00  LDD2074 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 32.00  LDD2074 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 25.99  LDD2074 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 25.99  LDD2074 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 9.45  LDD2074 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 9.45  LDD2074 
Protein O-GlcNAcase (OGA) LDTP00988 16.11  LDD2074 
Protein O-GlcNAcase (OGA) LDTP00988 16.11  LDD2074 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 19.29  LDD2074 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 19.29  LDD2074 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 16.45  LDD2074 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 16.45  LDD2074 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 31.12  LDD2074 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 31.12  LDD2074 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 30.91  LDD2074 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 30.91  LDD2074 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 26.72  LDD2074 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 26.72  LDD2074 
RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) LDTP05588 11.63  LDD2074 
RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) LDTP05588 11.63  LDD2074 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 13.00  LDD2074 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 13.00  LDD2074 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 14.32  LDD2074 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 14.32  LDD2074 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 13.00  LDD2074 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 13.00  LDD2074 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 10.27  LDD2074 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 10.27  LDD2074 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 25.11  LDD2074 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 25.11  LDD2074 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 43.71  LDD2074 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 43.71  LDD2074 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 9.32  LDD2074 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 9.32  LDD2074 
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⏷ Show the Full List of 154 Enzyme
82 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 10.63  LDD2074 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 10.63  LDD2074 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 53.82  LDD2074 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 53.82  LDD2074 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 47.50  LDD2074 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 47.50  LDD2074 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 50.21  LDD2074 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 50.21  LDD2074 
Erlin-1 (ERLIN1) LDTP01234 9.00  LDD2074 
Erlin-1 (ERLIN1) LDTP01234 9.00  LDD2074 
Erlin-2 (ERLIN2) LDTP01455 9.38  LDD2074 
Erlin-2 (ERLIN2) LDTP01455 9.38  LDD2074 
Intraflagellar transport protein 56 (IFT56) LDTP00010 12.04  LDD2074 
Intraflagellar transport protein 56 (IFT56) LDTP00010 12.04  LDD2074 
Lysosome membrane protein 2 (SCARB2) LDTP06034 50.21  LDD2074 
Lysosome membrane protein 2 (SCARB2) LDTP06034 50.21  LDD2074 
Metaxin-1 (MTX1) LDTP05900 23.75  LDD2074 
Metaxin-1 (MTX1) LDTP05900 23.75  LDD2074 
MFS-type transporter SLC18B1 (SLC18B1) LDTP07462 23.26  LDD2074 
MFS-type transporter SLC18B1 (SLC18B1) LDTP07462 23.26  LDD2074 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 13.00  LDD2074 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 13.00  LDD2074 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 69.07  LDD2074 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 69.07  LDD2074 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 12.91  LDD2074 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 12.91  LDD2074 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 57.68  LDD2074 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 57.68  LDD2074 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 17.27  LDD2074 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 17.27  LDD2074 
Nucleoporin NDC1 (NDC1) LDTP11213 10.27  LDD2074 
Nucleoporin NDC1 (NDC1) LDTP11213 10.27  LDD2074 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 12.38  LDD2074 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 12.38  LDD2074 
Prosaposin (PSAP) LDTP02215 45.89  LDD2074 
Prosaposin (PSAP) LDTP02215 45.89  LDD2074 
Protein tweety homolog 3 (TTYH3) LDTP11615 35.26  LDD2074 
Protein tweety homolog 3 (TTYH3) LDTP11615 35.26  LDD2074 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 11.96  LDD2074 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 11.96  LDD2074 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 26.35  LDD2074 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 26.35  LDD2074 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 65.80  LDD2074 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 65.80  LDD2074 
Sodium-coupled neutral amino acid symporter 1 (SLC38A1) LDTP11824 8.94  LDD2074 
Sodium-coupled neutral amino acid symporter 1 (SLC38A1) LDTP11824 8.94  LDD2074 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 22.16  LDD2074 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 22.16  LDD2074 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 15.89  LDD2074 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 15.89  LDD2074 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 37.79  LDD2074 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 37.79  LDD2074 
Tetraspanin-3 (TSPAN3) LDTP16813 24.25  LDD2074 
Tetraspanin-3 (TSPAN3) LDTP16813 24.25  LDD2074 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 18.13  LDD2074 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 18.13  LDD2074 
Translocator protein (TSPO) LDTP03546 10.63  LDD2074 
Translocator protein (TSPO) LDTP03546 10.63  LDD2074 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 22.78  LDD2074 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 22.78  LDD2074 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 10.34  LDD2074 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 10.34  LDD2074 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 12.91  LDD2074 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 12.91  LDD2074 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 10.70  LDD2074 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 10.70  LDD2074 
Transmembrane emp24 domain-containing protein 9 (TMED9) LDTP11291 9.58  LDD2074 
Transmembrane emp24 domain-containing protein 9 (TMED9) LDTP11291 9.58  LDD2074 
Transmembrane protein 160 (TMEM160) LDTP20002 16.80  LDD2074 
Transmembrane protein 160 (TMEM160) LDTP20002 16.80  LDD2074 
Transmembrane protein 65 (TMEM65) LDTP07583 8.94  LDD2074 
Transmembrane protein 65 (TMEM65) LDTP07583 8.94  LDD2074 
Transmembrane protein 87A (TMEM87A) LDTP15481 14.72  LDD2074 
Transmembrane protein 87A (TMEM87A) LDTP15481 14.72  LDD2074 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 24.42  LDD2074 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 24.42  LDD2074 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 42.52  LDD2074 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 42.52  LDD2074 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 40.79  LDD2074 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 40.79  LDD2074 
Zinc transporter 7 (SLC30A7) LDTP09180 14.22  LDD2074 
Zinc transporter 7 (SLC30A7) LDTP09180 14.22  LDD2074 
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⏷ Show the Full List of 82 Transporter and channel
2 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Paraspeckle component 1 (PSPC1) LDTP09694 9.99  LDD2074 
Paraspeckle component 1 (PSPC1) LDTP09694 9.99  LDD2074 
------------------------------------------------------------------------------------
2 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 8.28  LDD2074 
Basigin (BSG) LDTP03772 8.28  LDD2074 
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96 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 13.45  LDD2074 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 13.45  LDD2074 
Apolipoprotein L2 (APOL2) LDTP11076 46.21  LDD2074 
Apolipoprotein L2 (APOL2) LDTP11076 46.21  LDD2074 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 17.63  LDD2074 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 17.63  LDD2074 
Clustered mitochondria protein homolog (CLUH) LDTP14486 20.11  LDD2074 
Clustered mitochondria protein homolog (CLUH) LDTP14486 20.11  LDD2074 
Collectin-12 (COLEC12) LDTP07031 13.09  LDD2074 
Collectin-12 (COLEC12) LDTP07031 13.09  LDD2074 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 10.13  LDD2074 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 10.13  LDD2074 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 33.13  LDD2074 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 33.13  LDD2074 
Cytoplasmic FMR1-interacting protein 2 (CYFIP2) LDTP10289 9.45  LDD2074 
Cytoplasmic FMR1-interacting protein 2 (CYFIP2) LDTP10289 9.45  LDD2074 
DNA damage-binding protein 1 (DDB1) LDTP06543 13.64  LDD2074 
DNA damage-binding protein 1 (DDB1) LDTP06543 13.64  LDD2074 
Elongator complex protein 2 (ELP2) LDTP07400 11.16  LDD2074 
Elongator complex protein 2 (ELP2) LDTP07400 11.16  LDD2074 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 23.10  LDD2074 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 23.10  LDD2074 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 59.30  LDD2074 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 59.30  LDD2074 
Eukaryotic translation initiation factor 3 subunit L (EIF3L) LDTP13813 8.57  LDD2074 
Eukaryotic translation initiation factor 3 subunit L (EIF3L) LDTP13813 8.57  LDD2074 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 14.42  LDD2074 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 14.42  LDD2074 
Ganglioside GM2 activator (GM2A) LDTP02927 15.35  LDD2074 
Ganglioside GM2 activator (GM2A) LDTP02927 15.35  LDD2074 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 19.03  LDD2074 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 19.03  LDD2074 
Immunoglobulin-binding protein 1 (IGBP1) LDTP05089 17.15  LDD2074 
Immunoglobulin-binding protein 1 (IGBP1) LDTP05089 17.15  LDD2074 
Large proline-rich protein BAG6 (BAG6) LDTP04094 9.92  LDD2074 
Large proline-rich protein BAG6 (BAG6) LDTP04094 9.92  LDD2074 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 11.24  LDD2074 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 11.24  LDD2074 
Mdm2-binding protein (MTBP) LDTP15714 13.93  LDD2074 
Mdm2-binding protein (MTBP) LDTP15714 13.93  LDD2074 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 16.45  LDD2074 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 16.45  LDD2074 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 99.73  LDD2074 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 99.73  LDD2074 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 24.59  LDD2074 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 24.59  LDD2074 
Nicastrin (NCSTN) LDTP09787 8.63  LDD2074 
Nicastrin (NCSTN) LDTP09787 8.63  LDD2074 
Nucleobindin-1 (NUCB1) LDTP05375 12.47  LDD2074 
Nucleobindin-1 (NUCB1) LDTP05375 12.47  LDD2074 
Nucleobindin-2 (NUCB2) LDTP05160 20.82  LDD2074 
Nucleobindin-2 (NUCB2) LDTP05160 20.82  LDD2074 
Nurim (NRM) LDTP08606 8.46  LDD2074 
Nurim (NRM) LDTP08606 8.46  LDD2074 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 24.76  LDD2074 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 24.76  LDD2074 
Polyadenylate-binding protein-interacting protein 2 (PAIP2) LDTP11044 8.75  LDD2074 
Polyadenylate-binding protein-interacting protein 2 (PAIP2) LDTP11044 8.75  LDD2074 
Protein FAM114A2 (FAM114A2) LDTP16080 15.67  LDD2074 
Protein FAM114A2 (FAM114A2) LDTP16080 15.67  LDD2074 
Protein FAM136A (FAM136A) LDTP18132 18.77  LDD2074 
Protein FAM136A (FAM136A) LDTP18132 18.77  LDD2074 
Protein FAM162A (FAM162A) LDTP10056 14.62  LDD2074 
Protein FAM162A (FAM162A) LDTP10056 14.62  LDD2074 
Protein SYS1 homolog (SYS1) LDTP08796 11.79  LDD2074 
Protein SYS1 homolog (SYS1) LDTP08796 11.79  LDD2074 
Protein unc-119 homolog A (UNC119) LDTP05868 18.38  LDD2074 
Protein unc-119 homolog A (UNC119) LDTP05868 18.38  LDD2074 
Protein unc-119 homolog B (UNC119B) LDTP00105 30.27  LDD2074 
Protein unc-119 homolog B (UNC119B) LDTP00105 30.27  LDD2074 
Rap guanine nucleotide exchange factor 2 (RAPGEF2) LDTP14058 9.99  LDD2074 
Rap guanine nucleotide exchange factor 2 (RAPGEF2) LDTP14058 9.99  LDD2074 
Reticulon-3 (RTN3) LDTP01522 31.56  LDD2074 
Reticulon-3 (RTN3) LDTP01522 31.56  LDD2074 
Reticulon-4 (RTN4) LDTP12412 11.63  LDD2074 
Reticulon-4 (RTN4) LDTP12412 11.63  LDD2074 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 12.04  LDD2074 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 12.04  LDD2074 
Syntaxin-18 (STX18) LDTP13086 13.36  LDD2074 
Syntaxin-18 (STX18) LDTP13086 13.36  LDD2074 
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (TAF6L) LDTP14263 8.46  LDD2074 
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (TAF6L) LDTP14263 8.46  LDD2074 
Tetraspanin-6 (TSPAN6) LDTP14458 26.54  LDD2074 
Tetraspanin-6 (TSPAN6) LDTP14458 26.54  LDD2074 
Tetratricopeptide repeat protein 38 (TTC38) LDTP19372 9.00  LDD2074 
Tetratricopeptide repeat protein 38 (TTC38) LDTP19372 9.00  LDD2074 
Translation initiation factor eIF2B subunit gamma (EIF2B3) LDTP12476 9.38  LDD2074 
Translation initiation factor eIF2B subunit gamma (EIF2B3) LDTP12476 9.38  LDD2074 
Transmembrane emp24 domain-containing protein 4 (TMED4) LDTP08153 9.00  LDD2074 
Transmembrane emp24 domain-containing protein 4 (TMED4) LDTP08153 9.00  LDD2074 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 22.94  LDD2074 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 22.94  LDD2074 
Vimentin (VIM) LDTP02297 8.69  LDD2074 
Vimentin (VIM) LDTP02297 8.69  LDD2074 
Wings apart-like protein homolog (WAPL) LDTP08094 14.32  LDD2074 
Wings apart-like protein homolog (WAPL) LDTP08094 14.32  LDD2074 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD2074 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587