Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C098  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP08728  Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) 10.1
 LDTP12628  Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) 9.0
 LDTP05758  S-methyl-5'-thioadenosine phosphorylase (MTAP) 6.5
Transporter and channel
Click to Show/Hide to Show 5 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP01059  Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) 16.2
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 12.5
 LDTP10913  Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) 8.0
 LDTP11813  Solute carrier family 25 member 32 (SLC25A32) 5.9
 LDTP07885  Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) 4.9
Other
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP15269  Large ribosomal subunit protein mL55 (MRPL55) 17.1
 LDTP03678  ER lumen protein-retaining receptor 2 (KDELR2) 11.5

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587