Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C408 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP16007 | Lipid droplet-associated hydrolase (LDAH) | 20.7 | ||||
| LDTP15422 | Prostaglandin reductase 3 (PTGR3) | 14.4 | ||||
| LDTP03540 | Heme oxygenase 2 (HMOX2) | 14.3 | ||||
| LDTP03198 | Ferrochelatase, mitochondrial (FECH) | 11.3 | ||||
| LDTP01241 | Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) | 11.1 | ||||
| LDTP01982 | NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) | 9.9 | ||||
| LDTP04004 | Lysosomal Pro-X carboxypeptidase (PRCP) | 9.1 | ||||
| LDTP05396 | Histone-lysine N-methyltransferase 2A (KMT2A) | 8.5 | ||||
| LDTP06617 | Ceramide glucosyltransferase (UGCG) | 8.3 | ||||
| LDTP11273 | N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) | 7.8 | ||||
| LDTP02175 | Epoxide hydrolase 1 (EPHX1) | 7.6 | ||||
| LDTP06200 | Delta(14)-sterol reductase LBR (LBR) | 7.5 | ||||
| LDTP16032 | Retinoid-inducible serine carboxypeptidase (SCPEP1) | 6.9 | ||||
| LDTP13282 | Prenylcysteine oxidase 1 (PCYOX1) | 6.6 | ||||
| LDTP04388 | Palmitoyl-protein thioesterase 1 (PPT1) | 6.4 | ||||
| LDTP12279 | Endoplasmic reticulum transmembrane helix translocase (ATP13A1) | 6.2 | ||||
| LDTP06375 | Delta(24)-sterol reductase (DHCR24) | 6.1 | ||||
| LDTP04565 | Methionine aminopeptidase 1 (METAP1) | 6.1 | ||||
| LDTP12363 | Lysophosphatidic acid phosphatase type 6 (ACP6) | 6.0 | ||||
| LDTP02005 | Lysosomal acid glucosylceramidase (GBA1) | 5.9 | ||||
| LDTP05758 | S-methyl-5'-thioadenosine phosphorylase (MTAP) | 5.9 | ||||
| LDTP04712 | Puromycin-sensitive aminopeptidase (NPEPPS) | 5.5 | ||||
| LDTP05905 | Acid ceramidase (ASAH1) | 5.4 | ||||
| LDTP01328 | CAAX prenyl protease 1 homolog (ZMPSTE24) | 5.4 | ||||
| LDTP15484 | Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) | 5.4 | ||||
| LDTP10032 | 7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) | 5.4 | ||||
| LDTP02359 | Heme oxygenase 1 (HMOX1) | 5.3 | ||||
| LDTP16040 | Glyoxalase domain-containing protein 4 (GLOD4) | 5.2 | ||||
| LDTP02505 | Lysosomal protective protein (CTSA) | 5.1 | ||||
| LDTP04285 | Proteasome subunit beta type-2 (PSMB2) | 5.1 | ||||
| LDTP11321 | Acetyl-CoA acetyltransferase, cytosolic (ACAT2) | 5.0 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP10913 | Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) | 28.1 | ||||
| LDTP11813 | Solute carrier family 25 member 32 (SLC25A32) | 11.6 | ||||
| LDTP06945 | Sigma intracellular receptor 2 (TMEM97) | 11.4 | ||||
| LDTP03277 | ER lumen protein-retaining receptor 1 (KDELR1) | 10.6 | ||||
| LDTP08881 | Transmembrane protein 199 (TMEM199) | 9.3 | ||||
| LDTP06034 | Lysosome membrane protein 2 (SCARB2) | 8.0 | ||||
| LDTP07885 | Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) | 7.8 | ||||
| LDTP09547 | Scavenger receptor class B member 1 (SCARB1) | 7.4 | ||||
| LDTP14099 | Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) | 6.8 | ||||
| LDTP12383 | Protein GPR108 (GPR108) | 6.8 | ||||
| LDTP18448 | Transmembrane 9 superfamily member 3 (TM9SF3) | 6.7 | ||||
| LDTP20002 | Transmembrane protein 160 (TMEM160) | 6.7 | ||||
| LDTP06426 | Translocating chain-associated membrane protein 1 (TRAM1) | 6.1 | ||||
| LDTP09968 | V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) | 5.9 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP00281 | Golgi integral membrane protein 4 (GOLIM4) | 17.3 | ||||
| LDTP03678 | ER lumen protein-retaining receptor 2 (KDELR2) | 16.7 | ||||
| LDTP12565 | Mitochondrial import receptor subunit TOM22 homolog (TOMM22) | 16.1 | ||||
| LDTP11076 | Apolipoprotein L2 (APOL2) | 10.9 | ||||
| LDTP14486 | Clustered mitochondria protein homolog (CLUH) | 10.3 | ||||
| LDTP05375 | Nucleobindin-1 (NUCB1) | 9.9 | ||||
| LDTP05160 | Nucleobindin-2 (NUCB2) | 7.5 | ||||
| LDTP07934 | Synaptic vesicle glycoprotein 2A (SV2A) | 7.4 | ||||
| LDTP15067 | Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) | 7.3 | ||||
| LDTP10056 | Protein FAM162A (FAM162A) | 6.1 | ||||
| LDTP04914 | Large ribosomal subunit protein uL24 (RPL26) | 6.1 | ||||
| LDTP01522 | Reticulon-3 (RTN3) | 5.5 | ||||
| LDTP13606 | Mammalian ependymin-related protein 1 (EPDR1) | 5.2 | ||||