Details of the Probe

General Information of Probe

Probe ID
LDPC0447
Probe Name
C213
Synonyms
Z4282860062
Probe Type
PAL-AfBPP Probe
Structure
2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 375.8
Lipid-water partition coefficient (xlogp) 2.6
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C19H22ClN3O3
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-1-[2-(2-chloro-6-methoxyphenyl)morpholin-4-yl]propan-1-one
Canonical SMILES
COC1=C(C(=CC=C1)Cl)C2CN(CCO2)C(=O)CCC3(N=N3)CCC#C
InChI
InChI=1S/C19H22ClN3O3/c1-3-4-9-19(21-22-19)10-8-17(24)23-11-12-26-16(13-23)18-14(20)6-5-7-15(18)25-2/h1,5-7,16H,4,8-13H2,2H3
InChIKey
AJLISZJEXGXFBF-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

176 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 26.35  LDD1887 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 26.35  LDD1887 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 18.77  LDD1887 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 18.77  LDD1887 
Acid ceramidase (ASAH1) LDTP05905 20.97  LDD1887 
Acid ceramidase (ASAH1) LDTP05905 20.97  LDD1887 
Adenosine deaminase (ADA) LDTP01803 27.28  LDD1887 
Adenosine deaminase (ADA) LDTP01803 27.28  LDD1887 
Adipocyte plasma membrane-associated protein (APMAP) LDTP12293 32.67  LDD1887 
Adipocyte plasma membrane-associated protein (APMAP) LDTP12293 32.67  LDD1887 
ADP-dependent glucokinase (ADPGK) LDTP11127 14.62  LDD1887 
ADP-dependent glucokinase (ADPGK) LDTP11127 14.62  LDD1887 
ADP-ribosylation factor-like protein 6 (ARL6) LDTP11708 14.52  LDD1887 
ADP-ribosylation factor-like protein 6 (ARL6) LDTP11708 14.52  LDD1887 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 17.39  LDD1887 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 17.39  LDD1887 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 17.39  LDD1887 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 17.39  LDD1887 
Beta-galactosidase (GLB1) LDTP02837 16.45  LDD1887 
Beta-galactosidase (GLB1) LDTP02837 16.45  LDD1887 
Beta-galactosidase-1-like protein 2 (GLB1L2) LDTP17633 15.35  LDD1887 
Beta-galactosidase-1-like protein 2 (GLB1L2) LDTP17633 15.35  LDD1887 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 14.62  LDD1887 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 14.62  LDD1887 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 17.88  LDD1887 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 17.88  LDD1887 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 18.90  LDD1887 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 18.90  LDD1887 
Cartilage-associated protein (CRTAP) LDTP01300 14.52  LDD1887 
Cartilage-associated protein (CRTAP) LDTP01300 14.52  LDD1887 
CCR4-NOT transcription complex subunit 4 (CNOT4) LDTP01640 45.89  LDD1887 
CCR4-NOT transcription complex subunit 4 (CNOT4) LDTP01640 45.89  LDD1887 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 15.89  LDD1887 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 15.89  LDD1887 
Choline kinase alpha (CHKA) LDTP03787 17.51  LDD1887 
Choline kinase alpha (CHKA) LDTP03787 17.51  LDD1887 
Chondroitin sulfate N-acetylgalactosaminyltransferase 2 (CSGALNACT2) LDTP08933 19.29  LDD1887 
Chondroitin sulfate N-acetylgalactosaminyltransferase 2 (CSGALNACT2) LDTP08933 19.29  LDD1887 
COP9 signalosome complex subunit 4 (COPS4) LDTP11187 35.02  LDD1887 
COP9 signalosome complex subunit 4 (COPS4) LDTP11187 35.02  LDD1887 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 20.25  LDD1887 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 20.25  LDD1887 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 37.01  LDD1887 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 37.01  LDD1887 
Cytochrome b5 type B (CYB5B) LDTP00697 23.10  LDD1887 
Cytochrome b5 type B (CYB5B) LDTP00697 23.10  LDD1887 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 15.78  LDD1887 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 15.78  LDD1887 
DCN1-like protein 4 (DCUN1D4) LDTP09799 38.59  LDD1887 
DCN1-like protein 4 (DCUN1D4) LDTP09799 38.59  LDD1887 
DCN1-like protein 5 (DCUN1D5) LDTP11199 36.76  LDD1887 
DCN1-like protein 5 (DCUN1D5) LDTP11199 36.76  LDD1887 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 19.84  LDD1887 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 19.84  LDD1887 
Delta(24)-sterol reductase (DHCR24) LDTP06375 26.91  LDD1887 
Delta(24)-sterol reductase (DHCR24) LDTP06375 26.91  LDD1887 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 25.28  LDD1887 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 25.28  LDD1887 
Dihydrofolate reductase (DHFR) LDTP01769 16.00  LDD1887 
Dihydrofolate reductase (DHFR) LDTP01769 16.00  LDD1887 
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (DLST) LDTP03829 19.97  LDD1887 
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (DLST) LDTP03829 19.97  LDD1887 
Elongation factor 1-alpha 2 (EEF1A2) LDTP05460 14.42  LDD1887 
Elongation factor 1-alpha 2 (EEF1A2) LDTP05460 14.42  LDD1887 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 15.67  LDD1887 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 15.67  LDD1887 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 19.43  LDD1887 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 19.43  LDD1887 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 15.89  LDD1887 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 15.89  LDD1887 
Glutathione S-transferase A4 (GSTA4) LDTP00575 83.87  LDD1887 
Glutathione S-transferase A4 (GSTA4) LDTP00575 83.87  LDD1887 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 38.32  LDD1887 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 38.32  LDD1887 
Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD2) LDTP04032 14.32  LDD1887 
Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD2) LDTP04032 14.32  LDD1887 
Helicase MOV-10 (MOV10) LDTP12233 15.78  LDD1887 
Helicase MOV-10 (MOV10) LDTP12233 15.78  LDD1887 
Heme oxygenase 1 (HMOX1) LDTP02359 24.08  LDD1887 
Heme oxygenase 1 (HMOX1) LDTP02359 24.08  LDD1887 
Heme oxygenase 2 (HMOX2) LDTP03540 35.51  LDD1887 
Heme oxygenase 2 (HMOX2) LDTP03540 35.51  LDD1887 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 14.93  LDD1887 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 14.93  LDD1887 
Ketosamine-3-kinase (FN3KRP) LDTP16025 15.03  LDD1887 
Ketosamine-3-kinase (FN3KRP) LDTP16025 15.03  LDD1887 
L-2-hydroxyglutarate dehydrogenase, mitochondrial (L2HGDH) LDTP12105 15.35  LDD1887 
L-2-hydroxyglutarate dehydrogenase, mitochondrial (L2HGDH) LDTP12105 15.35  LDD1887 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 14.52  LDD1887 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 14.52  LDD1887 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 15.78  LDD1887 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 15.78  LDD1887 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 16.91  LDD1887 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 16.91  LDD1887 
Lysosomal acid phosphatase (ACP2) LDTP02539 15.14  LDD1887 
Lysosomal acid phosphatase (ACP2) LDTP02539 15.14  LDD1887 
Lysosomal alpha-glucosidase (GAA) LDTP02486 16.22  LDD1887 
Lysosomal alpha-glucosidase (GAA) LDTP02486 16.22  LDD1887 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 19.84  LDD1887 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 19.84  LDD1887 
Lysosomal protective protein (CTSA) LDTP02505 22.16  LDD1887 
Lysosomal protective protein (CTSA) LDTP02505 22.16  LDD1887 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 25.46  LDD1887 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 25.46  LDD1887 
Methionine aminopeptidase 1 (METAP1) LDTP04565 17.75  LDD1887 
Methionine aminopeptidase 1 (METAP1) LDTP04565 17.75  LDD1887 
Mitochondrial intermediate peptidase (MIPEP) LDTP10981 16.11  LDD1887 
Mitochondrial intermediate peptidase (MIPEP) LDTP10981 16.11  LDD1887 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 29.45  LDD1887 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 29.45  LDD1887 
Myotubularin-related protein 12 (MTMR12) LDTP11617 15.56  LDD1887 
Myotubularin-related protein 12 (MTMR12) LDTP11617 15.56  LDD1887 
N-acetylglucosamine-6-sulfatase (GNS) LDTP02799 22.78  LDD1887 
N-acetylglucosamine-6-sulfatase (GNS) LDTP02799 22.78  LDD1887 
NAD-capped RNA hydrolase NUDT12 (NUDT12) LDTP11081 17.03  LDD1887 
NAD-capped RNA hydrolase NUDT12 (NUDT12) LDTP11081 17.03  LDD1887 
NAD-dependent protein deacetylase sirtuin-2 (SIRT2) LDTP08598 14.52  LDD1887 
NAD-dependent protein deacetylase sirtuin-2 (SIRT2) LDTP08598 14.52  LDD1887 
NADH dehydrogenase 1 alpha subcomplex subunit 7 (NDUFA7) LDTP01518 20.25  LDD1887 
NADH dehydrogenase 1 alpha subcomplex subunit 7 (NDUFA7) LDTP01518 20.25  LDD1887 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 54.57  LDD1887 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 54.57  LDD1887 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 20.97  LDD1887 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 20.97  LDD1887 
NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) LDTP01168 16.80  LDD1887 
NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) LDTP01168 16.80  LDD1887 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 39.40  LDD1887 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 39.40  LDD1887 
Obg-like ATPase 1 (OLA1) LDTP12610 18.25  LDD1887 
Obg-like ATPase 1 (OLA1) LDTP12610 18.25  LDD1887 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 55.33  LDD1887 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 55.33  LDD1887 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 26.72  LDD1887 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 26.72  LDD1887 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 17.15  LDD1887 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 17.15  LDD1887 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 32.00  LDD1887 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 32.00  LDD1887 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 21.11  LDD1887 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 21.11  LDD1887 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 16.22  LDD1887 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 16.22  LDD1887 
Prostaglandin reductase 3 (PTGR3) LDTP15422 29.45  LDD1887 
Prostaglandin reductase 3 (PTGR3) LDTP15422 29.45  LDD1887 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 19.70  LDD1887 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 19.70  LDD1887 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 29.65  LDD1887 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 29.65  LDD1887 
Protein farnesyltransferase subunit beta (FNTB) LDTP04247 22.01  LDD1887 
Protein farnesyltransferase subunit beta (FNTB) LDTP04247 22.01  LDD1887 
Protein O-GlcNAcase (OGA) LDTP00988 19.43  LDD1887 
Protein O-GlcNAcase (OGA) LDTP00988 19.43  LDD1887 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 26.91  LDD1887 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 26.91  LDD1887 
Pseudouridylate synthase RPUSD2 (RPUSD2) LDTP15370 61.82  LDD1887 
Pseudouridylate synthase RPUSD2 (RPUSD2) LDTP15370 61.82  LDD1887 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 17.15  LDD1887 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 17.15  LDD1887 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 53.45  LDD1887 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 53.45  LDD1887 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 32.00  LDD1887 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 32.00  LDD1887 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 15.56  LDD1887 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 15.56  LDD1887 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 14.72  LDD1887 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 14.72  LDD1887 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 20.53  LDD1887 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 20.53  LDD1887 
Ubiquitin thioesterase OTUB1 (OTUB1) LDTP10318 18.25  LDD1887 
Ubiquitin thioesterase OTUB1 (OTUB1) LDTP10318 18.25  LDD1887 
Ubiquitin-protein ligase E3A (UBE3A) LDTP05446 14.83  LDD1887 
Ubiquitin-protein ligase E3A (UBE3A) LDTP05446 14.83  LDD1887 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 24.08  LDD1887 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 24.08  LDD1887 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 23.10  LDD1887 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 23.10  LDD1887 
------------------------------------------------------------------------------------
⏷ Show the Full List of 176 Enzyme
112 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 14.83  LDD1887 
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 14.83  LDD1887 
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 17.39  LDD1887 
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 17.39  LDD1887 
Amyloid-beta precursor protein (APP) LDTP02071 16.68  LDD1887 
Amyloid-beta precursor protein (APP) LDTP02071 16.68  LDD1887 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 14.93  LDD1887 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 14.93  LDD1887 
ATP synthase subunit a (MT-ATP6) LDTP01804 17.15  LDD1887 
ATP synthase subunit a (MT-ATP6) LDTP01804 17.15  LDD1887 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 23.92  LDD1887 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 23.92  LDD1887 
BOS complex subunit NCLN (NCLN) LDTP10036 16.34  LDD1887 
BOS complex subunit NCLN (NCLN) LDTP10036 16.34  LDD1887 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 72.00  LDD1887 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 72.00  LDD1887 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 84.45  LDD1887 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 84.45  LDD1887 
Exportin-1 (XPO1) LDTP00501 25.28  LDD1887 
Exportin-1 (XPO1) LDTP00501 25.28  LDD1887 
Exportin-4 (XPO4) LDTP11607 16.11  LDD1887 
Exportin-4 (XPO4) LDTP11607 16.11  LDD1887 
Exportin-T (XPOT) LDTP00810 15.03  LDD1887 
Exportin-T (XPOT) LDTP00810 15.03  LDD1887 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 15.45  LDD1887 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 15.45  LDD1887 
Integral membrane protein 2C (ITM2C) LDTP12451 14.42  LDD1887 
Integral membrane protein 2C (ITM2C) LDTP12451 14.42  LDD1887 
Lysosome membrane protein 2 (SCARB2) LDTP06034 30.70  LDD1887 
Lysosome membrane protein 2 (SCARB2) LDTP06034 30.70  LDD1887 
Lysosome-associated membrane glycoprotein 2 (LAMP2) LDTP02655 17.75  LDD1887 
Lysosome-associated membrane glycoprotein 2 (LAMP2) LDTP02655 17.75  LDD1887 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 21.56  LDD1887 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 21.56  LDD1887 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 17.15  LDD1887 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 17.15  LDD1887 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 17.27  LDD1887 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 17.27  LDD1887 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 14.32  LDD1887 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 14.32  LDD1887 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 31.56  LDD1887 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 31.56  LDD1887 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 27.10  LDD1887 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 27.10  LDD1887 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 26.72  LDD1887 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 26.72  LDD1887 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 99.73  LDD1887 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 99.73  LDD1887 
Mpv17-like protein 2 (MPV17L2) LDTP14952 15.03  LDD1887 
Mpv17-like protein 2 (MPV17L2) LDTP14952 15.03  LDD1887 
NPC intracellular cholesterol transporter 2 (NPC2) LDTP04940 17.03  LDD1887 
NPC intracellular cholesterol transporter 2 (NPC2) LDTP04940 17.03  LDD1887 
Phosphatidylinositol transfer protein alpha isoform (PITPNA) LDTP05236 14.52  LDD1887 
Phosphatidylinositol transfer protein alpha isoform (PITPNA) LDTP05236 14.52  LDD1887 
Prosaposin (PSAP) LDTP02215 43.11  LDD1887 
Prosaposin (PSAP) LDTP02215 43.11  LDD1887 
Protein FAM8A1 (FAM8A1) LDTP16190 37.79  LDD1887 
Protein FAM8A1 (FAM8A1) LDTP16190 37.79  LDD1887 
Protein GPR107 (GPR107) LDTP07236 28.64  LDD1887 
Protein GPR107 (GPR107) LDTP07236 28.64  LDD1887 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 16.80  LDD1887 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 16.80  LDD1887 
Proton-coupled zinc antiporter SLC30A5 (SLC30A5) LDTP09294 16.22  LDD1887 
Proton-coupled zinc antiporter SLC30A5 (SLC30A5) LDTP09294 16.22  LDD1887 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 19.03  LDD1887 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 19.03  LDD1887 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 20.53  LDD1887 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 20.53  LDD1887 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 67.18  LDD1887 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 67.18  LDD1887 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 33.59  LDD1887 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 33.59  LDD1887 
Solute carrier family 25 member 44 (SLC25A44) LDTP15733 39.95  LDD1887 
Solute carrier family 25 member 44 (SLC25A44) LDTP15733 39.95  LDD1887 
SUN domain-containing protein 2 (SUN2) LDTP13256 19.16  LDD1887 
SUN domain-containing protein 2 (SUN2) LDTP13256 19.16  LDD1887 
Surfeit locus protein 4 (SURF4) LDTP00592 24.25  LDD1887 
Surfeit locus protein 4 (SURF4) LDTP00592 24.25  LDD1887 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 37.01  LDD1887 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 37.01  LDD1887 
Syntaxin-5 (STX5) LDTP05780 15.24  LDD1887 
Syntaxin-5 (STX5) LDTP05780 15.24  LDD1887 
Syntenin-1 (SDCBP) LDTP00310 24.25  LDD1887 
Syntenin-1 (SDCBP) LDTP00310 24.25  LDD1887 
Tetraspanin-3 (TSPAN3) LDTP16813 26.91  LDD1887 
Tetraspanin-3 (TSPAN3) LDTP16813 26.91  LDD1887 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 28.64  LDD1887 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 28.64  LDD1887 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 33.36  LDD1887 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 33.36  LDD1887 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 18.00  LDD1887 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 18.00  LDD1887 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 14.72  LDD1887 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 14.72  LDD1887 
Transmembrane protein 126A (TMEM126A) LDTP15948 49.52  LDD1887 
Transmembrane protein 126A (TMEM126A) LDTP15948 49.52  LDD1887 
Transmembrane protein 160 (TMEM160) LDTP20002 38.32  LDD1887 
Transmembrane protein 160 (TMEM160) LDTP20002 38.32  LDD1887 
Transmembrane protein 199 (TMEM199) LDTP08881 28.64  LDD1887 
Transmembrane protein 199 (TMEM199) LDTP08881 28.64  LDD1887 
Transmembrane protein 59 (TMEM59) LDTP11406 31.78  LDD1887 
Transmembrane protein 59 (TMEM59) LDTP11406 31.78  LDD1887 
Transmembrane protein 87A (TMEM87A) LDTP15481 19.16  LDD1887 
Transmembrane protein 87A (TMEM87A) LDTP15481 19.16  LDD1887 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 19.84  LDD1887 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 19.84  LDD1887 
Vang-like protein 1 (VANGL1) LDTP09288 15.67  LDD1887 
Vang-like protein 1 (VANGL1) LDTP09288 15.67  LDD1887 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 46.53  LDD1887 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 46.53  LDD1887 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 39.95  LDD1887 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 39.95  LDD1887 
------------------------------------------------------------------------------------
⏷ Show the Full List of 112 Transporter and channel
4 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Chromatin accessibility complex protein 1 (CHRAC1) LDTP12507 14.93  LDD1887 
Chromatin accessibility complex protein 1 (CHRAC1) LDTP12507 14.93  LDD1887 
Y-box-binding protein 1 (YBX1) LDTP05065 15.45  LDD1887 
Y-box-binding protein 1 (YBX1) LDTP05065 15.45  LDD1887 
------------------------------------------------------------------------------------
168 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 15.45  LDD1887 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 15.45  LDD1887 
Apolipoprotein L2 (APOL2) LDTP11076 32.00  LDD1887 
Apolipoprotein L2 (APOL2) LDTP11076 32.00  LDD1887 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 17.51  LDD1887 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 17.51  LDD1887 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 17.88  LDD1887 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 17.88  LDD1887 
Calmodulin-3 (CALM3) LDTP02443 21.71  LDD1887 
Calmodulin-3 (CALM3) LDTP02443 21.71  LDD1887 
Calumenin (CALU) LDTP00887 20.11  LDD1887 
Calumenin (CALU) LDTP00887 20.11  LDD1887 
CCR4-NOT transcription complex subunit 9 (CNOT9) LDTP09813 40.79  LDD1887 
CCR4-NOT transcription complex subunit 9 (CNOT9) LDTP09813 40.79  LDD1887 
Centrosomal protein 43 (CEP43) LDTP01652 17.75  LDD1887 
Centrosomal protein 43 (CEP43) LDTP01652 17.75  LDD1887 
Clustered mitochondria protein homolog (CLUH) LDTP14486 20.39  LDD1887 
Clustered mitochondria protein homolog (CLUH) LDTP14486 20.39  LDD1887 
COP9 signalosome complex subunit 7a (COPS7A) LDTP13170 15.03  LDD1887 
COP9 signalosome complex subunit 7a (COPS7A) LDTP13170 15.03  LDD1887 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 32.67  LDD1887 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 32.67  LDD1887 
Cytoplasmic dynein 2 intermediate chain 2 (DYNC2I2) LDTP10281 15.45  LDD1887 
Cytoplasmic dynein 2 intermediate chain 2 (DYNC2I2) LDTP10281 15.45  LDD1887 
DENN domain-containing protein 11 (DENND11) LDTP16577 15.35  LDD1887 
DENN domain-containing protein 11 (DENND11) LDTP16577 15.35  LDD1887 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 37.53  LDD1887 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 37.53  LDD1887 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 16.56  LDD1887 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 16.56  LDD1887 
Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ERGIC1) LDTP10046 17.27  LDD1887 
Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ERGIC1) LDTP10046 17.27  LDD1887 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 17.39  LDD1887 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 17.39  LDD1887 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 44.32  LDD1887 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 44.32  LDD1887 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 77.71  LDD1887 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 77.71  LDD1887 
Eukaryotic translation initiation factor 3 subunit L (EIF3L) LDTP13813 17.75  LDD1887 
Eukaryotic translation initiation factor 3 subunit L (EIF3L) LDTP13813 17.75  LDD1887 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 52.35  LDD1887 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 52.35  LDD1887 
Ganglioside GM2 activator (GM2A) LDTP02927 18.51  LDD1887 
Ganglioside GM2 activator (GM2A) LDTP02927 18.51  LDD1887 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 19.29  LDD1887 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 19.29  LDD1887 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 25.63  LDD1887 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 25.63  LDD1887 
HEAT repeat-containing protein 3 (HEATR3) LDTP15253 15.14  LDD1887 
HEAT repeat-containing protein 3 (HEATR3) LDTP15253 15.14  LDD1887 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 14.62  LDD1887 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 14.62  LDD1887 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 25.11  LDD1887 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 25.11  LDD1887 
Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2) LDTP04714 18.64  LDD1887 
Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2) LDTP04714 18.64  LDD1887 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 18.38  LDD1887 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 18.38  LDD1887 
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) LDTP14272 17.51  LDD1887 
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) LDTP14272 17.51  LDD1887 
Intraflagellar transport protein 52 homolog (IFT52) LDTP13952 17.27  LDD1887 
Intraflagellar transport protein 52 homolog (IFT52) LDTP13952 17.27  LDD1887 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 15.24  LDD1887 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 15.24  LDD1887 
Large proline-rich protein BAG6 (BAG6) LDTP04094 22.16  LDD1887 
Large proline-rich protein BAG6 (BAG6) LDTP04094 22.16  LDD1887 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 33.59  LDD1887 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 33.59  LDD1887 
Membralin (TMEM259) LDTP14939 15.67  LDD1887 
Membralin (TMEM259) LDTP14939 15.67  LDD1887 
Microtubule nucleation factor SSNA1 (SSNA1) LDTP00871 34.30  LDD1887 
Microtubule nucleation factor SSNA1 (SSNA1) LDTP00871 34.30  LDD1887 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 88.65  LDD1887 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 88.65  LDD1887 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 34.54  LDD1887 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 34.54  LDD1887 
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial (NFU1) LDTP13622 14.83  LDD1887 
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial (NFU1) LDTP13622 14.83  LDD1887 
Nucleobindin-1 (NUCB1) LDTP05375 22.47  LDD1887 
Nucleobindin-1 (NUCB1) LDTP05375 22.47  LDD1887 
Nucleobindin-2 (NUCB2) LDTP05160 92.41  LDD1887 
Nucleobindin-2 (NUCB2) LDTP05160 92.41  LDD1887 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 16.56  LDD1887 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 16.56  LDD1887 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 15.35  LDD1887 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 15.35  LDD1887 
Optic atrophy 3 protein (OPA3) LDTP16006 18.51  LDD1887 
Optic atrophy 3 protein (OPA3) LDTP16006 18.51  LDD1887 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 29.04  LDD1887 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 29.04  LDD1887 
PRELI domain-containing protein 1, mitochondrial (PRELID1) LDTP13807 16.34  LDD1887 
PRELI domain-containing protein 1, mitochondrial (PRELID1) LDTP13807 16.34  LDD1887 
Programmed cell death protein 5 (PDCD5) LDTP00417 16.80  LDD1887 
Programmed cell death protein 5 (PDCD5) LDTP00417 16.80  LDD1887 
Protein CEBPZOS (CEBPZOS) LDTP18883 49.18  LDD1887 
Protein CEBPZOS (CEBPZOS) LDTP18883 49.18  LDD1887 
Protein CutA (CUTA) LDTP01075 25.46  LDD1887 
Protein CutA (CUTA) LDTP01075 25.46  LDD1887 
Protein FAM114A2 (FAM114A2) LDTP16080 16.22  LDD1887 
Protein FAM114A2 (FAM114A2) LDTP16080 16.22  LDD1887 
Protein FAM136A (FAM136A) LDTP18132 17.03  LDD1887 
Protein FAM136A (FAM136A) LDTP18132 17.03  LDD1887 
Protein FAM162A (FAM162A) LDTP10056 38.85  LDD1887 
Protein FAM162A (FAM162A) LDTP10056 38.85  LDD1887 
Protein PALS2 (PALS2) LDTP16156 14.83  LDD1887 
Protein PALS2 (PALS2) LDTP16156 14.83  LDD1887 
Protein PBDC1 (PBDC1) LDTP19924 17.75  LDD1887 
Protein PBDC1 (PBDC1) LDTP19924 17.75  LDD1887 
Protein SET (SET) LDTP05277 16.00  LDD1887 
Protein SET (SET) LDTP05277 16.00  LDD1887 
Protein SYS1 homolog (SYS1) LDTP08796 31.34  LDD1887 
Protein SYS1 homolog (SYS1) LDTP08796 31.34  LDD1887 
Protein unc-119 homolog B (UNC119B) LDTP00105 42.22  LDD1887 
Protein unc-119 homolog B (UNC119B) LDTP00105 42.22  LDD1887 
Protein YIF1A (YIF1A) LDTP01494 15.56  LDD1887 
Protein YIF1A (YIF1A) LDTP01494 15.56  LDD1887 
Protocadherin Fat 1 (FAT1) LDTP06134 15.45  LDD1887 
Protocadherin Fat 1 (FAT1) LDTP06134 15.45  LDD1887 
Rab9 effector protein with kelch motifs (RABEPK) LDTP08130 32.90  LDD1887 
Rab9 effector protein with kelch motifs (RABEPK) LDTP08130 32.90  LDD1887 
Reticulon-3 (RTN3) LDTP01522 17.88  LDD1887 
Reticulon-3 (RTN3) LDTP01522 17.88  LDD1887 
RNA polymerase II-associated protein 1 (RPAP1) LDTP11327 15.56  LDD1887 
RNA polymerase II-associated protein 1 (RPAP1) LDTP11327 15.56  LDD1887 
RNA-binding protein 3 (RBM3) LDTP05226 19.84  LDD1887 
RNA-binding protein 3 (RBM3) LDTP05226 19.84  LDD1887 
RNA-binding protein EWS (EWSR1) LDTP05318 15.56  LDD1887 
RNA-binding protein EWS (EWSR1) LDTP05318 15.56  LDD1887 
SURP and G-patch domain-containing protein 1 (SUGP1) LDTP08577 15.67  LDD1887 
SURP and G-patch domain-containing protein 1 (SUGP1) LDTP08577 15.67  LDD1887 
Synaptogyrin-2 (SYNGR2) LDTP00859 14.42  LDD1887 
Synaptogyrin-2 (SYNGR2) LDTP00859 14.42  LDD1887 
Syntaxin-10 (STX10) LDTP00986 14.52  LDD1887 
Syntaxin-10 (STX10) LDTP00986 14.52  LDD1887 
Syntaxin-18 (STX18) LDTP13086 21.11  LDD1887 
Syntaxin-18 (STX18) LDTP13086 21.11  LDD1887 
Tetraspanin-6 (TSPAN6) LDTP14458 28.64  LDD1887 
Tetraspanin-6 (TSPAN6) LDTP14458 28.64  LDD1887 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 23.43  LDD1887 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 23.43  LDD1887 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 25.63  LDD1887 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 25.63  LDD1887 
Trophoblast glycoprotein (TPBG) LDTP05960 15.14  LDD1887 
Trophoblast glycoprotein (TPBG) LDTP05960 15.14  LDD1887 
Tropomyosin alpha-4 chain (TPM4) LDTP05068 14.83  LDD1887 
Tropomyosin alpha-4 chain (TPM4) LDTP05068 14.83  LDD1887 
Tubulin beta chain (TUBB) LDTP02205 18.00  LDD1887 
Tubulin beta chain (TUBB) LDTP02205 18.00  LDD1887 
Tubulin beta-2B chain (TUBB2B) LDTP11277 19.03  LDD1887 
Tubulin beta-2B chain (TUBB2B) LDTP11277 19.03  LDD1887 
Tubulin beta-3 chain (TUBB3) LDTP05904 14.72  LDD1887 
Tubulin beta-3 chain (TUBB3) LDTP05904 14.72  LDD1887 
Tubulin beta-4A chain (TUBB4A) LDTP02037 19.56  LDD1887 
Tubulin beta-4A chain (TUBB4A) LDTP02037 19.56  LDD1887 
Tubulin beta-6 chain (TUBB6) LDTP11233 15.03  LDD1887 
Tubulin beta-6 chain (TUBB6) LDTP11233 15.03  LDD1887 
Tudor and KH domain-containing protein (TDRKH) LDTP13922 14.42  LDD1887 
Tudor and KH domain-containing protein (TDRKH) LDTP13922 14.42  LDD1887 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 25.11  LDD1887 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 25.11  LDD1887 
Ubiquitin-associated protein 2 (UBAP2) LDTP07132 16.22  LDD1887 
Ubiquitin-associated protein 2 (UBAP2) LDTP07132 16.22  LDD1887 
UV excision repair protein RAD23 homolog A (RAD23A) LDTP04626 16.34  LDD1887 
UV excision repair protein RAD23 homolog A (RAD23A) LDTP04626 16.34  LDD1887 
Vimentin (VIM) LDTP02297 19.03  LDD1887 
Vimentin (VIM) LDTP02297 19.03  LDD1887 
WD repeat and coiled-coil-containing protein (WDCP) LDTP11995 14.72  LDD1887 
WD repeat and coiled-coil-containing protein (WDCP) LDTP11995 14.72  LDD1887 
------------------------------------------------------------------------------------
⏷ Show the Full List of 168 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1887 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587