Details of the Probe

General Information of Probe

Probe ID
LDPC0387
Probe Name
C145
Probe Type
PAL-AfBPP Probe
Structure
2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 326.335
Lipid-water partition coefficient (xlogp) 2.7006
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C16H15FN6O
Canonical SMILES
[H]C#CC([H])([H])C([H])([H])C1(C([H])([H])C([H])([H])C(=O)N([H])c2c([H])c(-n3nnc([H])c3[H])c([H])c([H])c2F)N=N1
InChI
InChI=1S/C16H15FN6O/c1-2-3-7-16(20-21-16)8-6-15(24)19-14-11-12(4-5-13(14)17)23-10-9-18-22-23/h1,4-5,9-11H,3,6-8H2,(H,19,24)
InChIKey
UADQXNBLWOHWKF-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

152 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
5'-3' exonuclease PLD3 (PLD3) LDTP08476 23.43  LDD1827 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 23.43  LDD1827 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 11.08  LDD1827 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 11.08  LDD1827 
Adenosine deaminase (ADA) LDTP01803 13.36  LDD1827 
Adenosine deaminase (ADA) LDTP01803 13.36  LDD1827 
Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) LDTP03560 9.65  LDD1827 
Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) LDTP03560 9.65  LDD1827 
Alpha-galactosidase A (GLA) LDTP02141 9.38  LDD1827 
Alpha-galactosidase A (GLA) LDTP02141 9.38  LDD1827 
Antigen peptide transporter 1 (TAP1) LDTP05408 8.51  LDD1827 
Antigen peptide transporter 1 (TAP1) LDTP05408 8.51  LDD1827 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 22.16  LDD1827 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 22.16  LDD1827 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 8.46  LDD1827 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 8.46  LDD1827 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 9.00  LDD1827 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 9.00  LDD1827 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 11.24  LDD1827 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 11.24  LDD1827 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 11.55  LDD1827 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 11.55  LDD1827 
Ceramide synthase 2 (CERS2) LDTP10329 15.24  LDD1827 
Ceramide synthase 2 (CERS2) LDTP10329 15.24  LDD1827 
DCN1-like protein 4 (DCUN1D4) LDTP09799 8.57  LDD1827 
DCN1-like protein 4 (DCUN1D4) LDTP09799 8.57  LDD1827 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 13.93  LDD1827 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 13.93  LDD1827 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 9.25  LDD1827 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 9.25  LDD1827 
Delta(24)-sterol reductase (DHCR24) LDTP06375 13.55  LDD1827 
Delta(24)-sterol reductase (DHCR24) LDTP06375 13.55  LDD1827 
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) LDTP05724 13.83  LDD1827 
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) LDTP05724 13.83  LDD1827 
Dihydrofolate reductase (DHFR) LDTP01769 8.57  LDD1827 
Dihydrofolate reductase (DHFR) LDTP01769 8.57  LDD1827 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 22.32  LDD1827 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 22.32  LDD1827 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 8.51  LDD1827 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 8.51  LDD1827 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 8.75  LDD1827 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 8.75  LDD1827 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 17.75  LDD1827 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 17.75  LDD1827 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 13.64  LDD1827 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 13.64  LDD1827 
Epoxide hydrolase 1 (EPHX1) LDTP02175 28.64  LDD1827 
Epoxide hydrolase 1 (EPHX1) LDTP02175 28.64  LDD1827 
Exonuclease 1 (EXO1) LDTP13751 16.68  LDD1827 
Exonuclease 1 (EXO1) LDTP13751 16.68  LDD1827 
Exosome complex component RRP42 (EXOSC7) LDTP06283 8.40  LDD1827 
Exosome complex component RRP42 (EXOSC7) LDTP06283 8.40  LDD1827 
Exosome RNA helicase MTR4 (MTREX) LDTP03975 23.10  LDD1827 
Exosome RNA helicase MTR4 (MTREX) LDTP03975 23.10  LDD1827 
Ferrochelatase, mitochondrial (FECH) LDTP03198 12.30  LDD1827 
Ferrochelatase, mitochondrial (FECH) LDTP03198 12.30  LDD1827 
Gamma-adducin (ADD3) LDTP13204 9.71  LDD1827 
Gamma-adducin (ADD3) LDTP13204 9.71  LDD1827 
Heme oxygenase 1 (HMOX1) LDTP02359 13.36  LDD1827 
Heme oxygenase 1 (HMOX1) LDTP02359 13.36  LDD1827 
Heme oxygenase 2 (HMOX2) LDTP03540 55.72  LDD1827 
Heme oxygenase 2 (HMOX2) LDTP03540 55.72  LDD1827 
Histone-lysine N-methyltransferase 2A (KMT2A) LDTP05396 8.06  LDD1827 
Histone-lysine N-methyltransferase 2A (KMT2A) LDTP05396 8.06  LDD1827 
Histone-lysine N-methyltransferase SMYD3 (SMYD3) LDTP12020 11.39  LDD1827 
Histone-lysine N-methyltransferase SMYD3 (SMYD3) LDTP12020 11.39  LDD1827 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 10.20  LDD1827 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 10.20  LDD1827 
Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) LDTP04211 15.78  LDD1827 
Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) LDTP04211 15.78  LDD1827 
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (AASDHPPT) LDTP12524 10.27  LDD1827 
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (AASDHPPT) LDTP12524 10.27  LDD1827 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 15.24  LDD1827 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 15.24  LDD1827 
Lanosterol synthase (LSS) LDTP04183 11.79  LDD1827 
Lanosterol synthase (LSS) LDTP04183 11.79  LDD1827 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 15.14  LDD1827 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 15.14  LDD1827 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 11.96  LDD1827 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 11.96  LDD1827 
Lysophospholipid acyltransferase 5 (LPCAT3) LDTP07504 11.39  LDD1827 
Lysophospholipid acyltransferase 5 (LPCAT3) LDTP07504 11.39  LDD1827 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 26.17  LDD1827 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 26.17  LDD1827 
Lysosomal protective protein (CTSA) LDTP02505 8.63  LDD1827 
Lysosomal protective protein (CTSA) LDTP02505 8.63  LDD1827 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 13.83  LDD1827 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 13.83  LDD1827 
Macrophage migration inhibitory factor (MIF) LDTP02713 12.64  LDD1827 
Macrophage migration inhibitory factor (MIF) LDTP02713 12.64  LDD1827 
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2) LDTP12227 18.38  LDD1827 
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2) LDTP12227 18.38  LDD1827 
NAD(P)H-hydrate epimerase (NAXE) LDTP09110 11.08  LDD1827 
NAD(P)H-hydrate epimerase (NAXE) LDTP09110 11.08  LDD1827 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 9.85  LDD1827 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 9.85  LDD1827 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 11.08  LDD1827 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 11.08  LDD1827 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 12.30  LDD1827 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 12.30  LDD1827 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 17.88  LDD1827 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 17.88  LDD1827 
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (PAOX) LDTP07620 9.38  LDD1827 
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (PAOX) LDTP07620 9.38  LDD1827 
Phospholipase A2 group XV (PLA2G15) LDTP09088 10.06  LDD1827 
Phospholipase A2 group XV (PLA2G15) LDTP09088 10.06  LDD1827 
Pirin (PIR) LDTP00325 9.32  LDD1827 
Pirin (PIR) LDTP00325 9.32  LDD1827 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 24.08  LDD1827 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 24.08  LDD1827 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 23.26  LDD1827 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 23.26  LDD1827 
Prolyl endopeptidase-like (PREPL) LDTP06849 19.70  LDD1827 
Prolyl endopeptidase-like (PREPL) LDTP06849 19.70  LDD1827 
Prostaglandin reductase 2 (PTGR2) LDTP08979 15.35  LDD1827 
Prostaglandin reductase 2 (PTGR2) LDTP08979 15.35  LDD1827 
Proteasome subunit alpha type-6 (PSMA6) LDTP04884 8.28  LDD1827 
Proteasome subunit alpha type-6 (PSMA6) LDTP04884 8.28  LDD1827 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 12.30  LDD1827 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 12.30  LDD1827 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 8.28  LDD1827 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 8.28  LDD1827 
Protein O-GlcNAcase (OGA) LDTP00988 10.20  LDD1827 
Protein O-GlcNAcase (OGA) LDTP00988 10.20  LDD1827 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 15.45  LDD1827 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 15.45  LDD1827 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 19.03  LDD1827 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 19.03  LDD1827 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 15.24  LDD1827 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 15.24  LDD1827 
Retinal dehydrogenase 2 (ALDH1A2) LDTP01419 10.34  LDD1827 
Retinal dehydrogenase 2 (ALDH1A2) LDTP01419 10.34  LDD1827 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 16.91  LDD1827 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 16.91  LDD1827 
Ribosomal protein S6 kinase alpha-1 (RPS6KA1) LDTP06384 10.70  LDD1827 
Ribosomal protein S6 kinase alpha-1 (RPS6KA1) LDTP06384 10.70  LDD1827 
Ribosomal protein S6 kinase alpha-3 (RPS6KA3) LDTP04471 8.17  LDD1827 
Ribosomal protein S6 kinase alpha-3 (RPS6KA3) LDTP04471 8.17  LDD1827 
RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) LDTP05588 13.09  LDD1827 
RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) LDTP05588 13.09  LDD1827 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 17.39  LDD1827 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 17.39  LDD1827 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 13.55  LDD1827 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 13.55  LDD1827 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 8.06  LDD1827 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 8.06  LDD1827 
Sphingomyelin phosphodiesterase (SMPD1) LDTP02896 11.24  LDD1827 
Sphingomyelin phosphodiesterase (SMPD1) LDTP02896 11.24  LDD1827 
Ubiquitin carboxyl-terminal hydrolase 47 (USP47) LDTP10495 10.27  LDD1827 
Ubiquitin carboxyl-terminal hydrolase 47 (USP47) LDTP10495 10.27  LDD1827 
Ubiquitin thioesterase OTUB1 (OTUB1) LDTP10318 8.34  LDD1827 
Ubiquitin thioesterase OTUB1 (OTUB1) LDTP10318 8.34  LDD1827 
------------------------------------------------------------------------------------
⏷ Show the Full List of 152 Enzyme
58 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
45 kDa calcium-binding protein (SDF4) LDTP11116 8.69  LDD1827 
45 kDa calcium-binding protein (SDF4) LDTP11116 8.69  LDD1827 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 8.17  LDD1827 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 8.17  LDD1827 
H(+)/Cl(-) exchange transporter 6 (CLCN6) LDTP04462 22.01  LDD1827 
H(+)/Cl(-) exchange transporter 6 (CLCN6) LDTP04462 22.01  LDD1827 
Integral membrane protein 2C (ITM2C) LDTP12451 10.13  LDD1827 
Integral membrane protein 2C (ITM2C) LDTP12451 10.13  LDD1827 
Lysosome membrane protein 2 (SCARB2) LDTP06034 27.67  LDD1827 
Lysosome membrane protein 2 (SCARB2) LDTP06034 27.67  LDD1827 
Magnesium transporter NIPA3 (NIPAL1) LDTP17362 30.48  LDD1827 
Magnesium transporter NIPA3 (NIPAL1) LDTP17362 30.48  LDD1827 
Major facilitator superfamily domain-containing protein 8 (MFSD8) LDTP09261 11.08  LDD1827 
Major facilitator superfamily domain-containing protein 8 (MFSD8) LDTP09261 11.08  LDD1827 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 10.41  LDD1827 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 10.41  LDD1827 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 13.18  LDD1827 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 13.18  LDD1827 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 31.12  LDD1827 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 31.12  LDD1827 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 20.82  LDD1827 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 20.82  LDD1827 
Monocarboxylate transporter 1 (SLC16A1) LDTP04592 15.03  LDD1827 
Monocarboxylate transporter 1 (SLC16A1) LDTP04592 15.03  LDD1827 
Mpv17-like protein 2 (MPV17L2) LDTP14952 20.39  LDD1827 
Mpv17-like protein 2 (MPV17L2) LDTP14952 20.39  LDD1827 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 44.32  LDD1827 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 44.32  LDD1827 
Protein GPR107 (GPR107) LDTP07236 11.88  LDD1827 
Protein GPR107 (GPR107) LDTP07236 11.88  LDD1827 
Protein spinster homolog 1 (SPNS1) LDTP11844 8.40  LDD1827 
Protein spinster homolog 1 (SPNS1) LDTP11844 8.40  LDD1827 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 9.99  LDD1827 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 9.99  LDD1827 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 15.89  LDD1827 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 15.89  LDD1827 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 18.77  LDD1827 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 18.77  LDD1827 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 25.63  LDD1827 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 25.63  LDD1827 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 15.67  LDD1827 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 15.67  LDD1827 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 9.65  LDD1827 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 9.65  LDD1827 
Surfeit locus protein 4 (SURF4) LDTP00592 9.58  LDD1827 
Surfeit locus protein 4 (SURF4) LDTP00592 9.58  LDD1827 
Tetraspanin-3 (TSPAN3) LDTP16813 8.17  LDD1827 
Tetraspanin-3 (TSPAN3) LDTP16813 8.17  LDD1827 
Transmembrane protein 199 (TMEM199) LDTP08881 9.51  LDD1827 
Transmembrane protein 199 (TMEM199) LDTP08881 9.51  LDD1827 
Transmembrane protein 87A (TMEM87A) LDTP15481 10.78  LDD1827 
Transmembrane protein 87A (TMEM87A) LDTP15481 10.78  LDD1827 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 9.25  LDD1827 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 9.25  LDD1827 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 19.29  LDD1827 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 19.29  LDD1827 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 18.13  LDD1827 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 18.13  LDD1827 
------------------------------------------------------------------------------------
⏷ Show the Full List of 58 Transporter and channel
100 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 8.82  LDD1827 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 8.82  LDD1827 
Apolipoprotein L2 (APOL2) LDTP11076 15.24  LDD1827 
Apolipoprotein L2 (APOL2) LDTP11076 15.24  LDD1827 
Calumenin (CALU) LDTP00887 9.00  LDD1827 
Calumenin (CALU) LDTP00887 9.00  LDD1827 
Centrosomal protein 43 (CEP43) LDTP01652 15.45  LDD1827 
Centrosomal protein 43 (CEP43) LDTP01652 15.45  LDD1827 
Clustered mitochondria protein homolog (CLUH) LDTP14486 26.72  LDD1827 
Clustered mitochondria protein homolog (CLUH) LDTP14486 26.72  LDD1827 
Cold-inducible RNA-binding protein (CIRBP) LDTP06022 12.47  LDD1827 
Cold-inducible RNA-binding protein (CIRBP) LDTP06022 12.47  LDD1827 
Dynactin subunit 4 (DCTN4) LDTP13402 8.57  LDD1827 
Dynactin subunit 4 (DCTN4) LDTP13402 8.57  LDD1827 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 11.00  LDD1827 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 11.00  LDD1827 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 10.20  LDD1827 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 10.20  LDD1827 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 8.28  LDD1827 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 8.28  LDD1827 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 9.19  LDD1827 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 9.19  LDD1827 
Golgi apparatus protein 1 (GLG1) LDTP09920 10.78  LDD1827 
Golgi apparatus protein 1 (GLG1) LDTP09920 10.78  LDD1827 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 9.00  LDD1827 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 9.00  LDD1827 
Heme-binding protein 1 (HEBP1) LDTP16078 8.28  LDD1827 
Heme-binding protein 1 (HEBP1) LDTP16078 8.28  LDD1827 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 8.75  LDD1827 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 8.75  LDD1827 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 8.22  LDD1827 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 8.22  LDD1827 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 8.75  LDD1827 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 8.75  LDD1827 
Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2) LDTP04714 8.22  LDD1827 
Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2) LDTP04714 8.22  LDD1827 
Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) LDTP03614 8.22  LDD1827 
Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) LDTP03614 8.22  LDD1827 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 11.31  LDD1827 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 11.31  LDD1827 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 17.63  LDD1827 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 17.63  LDD1827 
Mdm2-binding protein (MTBP) LDTP15714 13.93  LDD1827 
Mdm2-binding protein (MTBP) LDTP15714 13.93  LDD1827 
Mediator of RNA polymerase II transcription subunit 4 (MED4) LDTP12377 10.70  LDD1827 
Mediator of RNA polymerase II transcription subunit 4 (MED4) LDTP12377 10.70  LDD1827 
Microtubule nucleation factor SSNA1 (SSNA1) LDTP00871 10.78  LDD1827 
Microtubule nucleation factor SSNA1 (SSNA1) LDTP00871 10.78  LDD1827 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 11.88  LDD1827 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 11.88  LDD1827 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 8.22  LDD1827 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 8.22  LDD1827 
Neudesin (NENF) LDTP13630 10.06  LDD1827 
Neudesin (NENF) LDTP13630 10.06  LDD1827 
Neuferricin (CYB5D2) LDTP15623 9.32  LDD1827 
Neuferricin (CYB5D2) LDTP15623 9.32  LDD1827 
Nucleobindin-2 (NUCB2) LDTP05160 13.45  LDD1827 
Nucleobindin-2 (NUCB2) LDTP05160 13.45  LDD1827 
Nucleolar protein 9 (NOP9) LDTP15283 8.57  LDD1827 
Nucleolar protein 9 (NOP9) LDTP15283 8.57  LDD1827 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 8.57  LDD1827 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 8.57  LDD1827 
Protein FAM114A2 (FAM114A2) LDTP16080 11.55  LDD1827 
Protein FAM114A2 (FAM114A2) LDTP16080 11.55  LDD1827 
Protein misato homolog 1 (MSTO1) LDTP11239 9.25  LDD1827 
Protein misato homolog 1 (MSTO1) LDTP11239 9.25  LDD1827 
Protein SET (SET) LDTP05277 8.46  LDD1827 
Protein SET (SET) LDTP05277 8.46  LDD1827 
Protein unc-119 homolog B (UNC119B) LDTP00105 18.13  LDD1827 
Protein unc-119 homolog B (UNC119B) LDTP00105 18.13  LDD1827 
Rap guanine nucleotide exchange factor 2 (RAPGEF2) LDTP14058 8.94  LDD1827 
Rap guanine nucleotide exchange factor 2 (RAPGEF2) LDTP14058 8.94  LDD1827 
Reticulocalbin-2 (RCN2) LDTP06097 11.79  LDD1827 
Reticulocalbin-2 (RCN2) LDTP06097 11.79  LDD1827 
RNA-binding motif protein, X chromosome (RBMX) LDTP03850 8.75  LDD1827 
RNA-binding motif protein, X chromosome (RBMX) LDTP03850 8.75  LDD1827 
RNA-binding protein 3 (RBM3) LDTP05226 14.03  LDD1827 
RNA-binding protein 3 (RBM3) LDTP05226 14.03  LDD1827 
RNA-binding protein FUS (FUS) LDTP03775 8.28  LDD1827 
RNA-binding protein FUS (FUS) LDTP03775 8.28  LDD1827 
Serine/arginine-rich splicing factor 2 (SRSF2) LDTP05280 9.85  LDD1827 
Serine/arginine-rich splicing factor 2 (SRSF2) LDTP05280 9.85  LDD1827 
TATA-binding protein-associated factor 2N (TAF15) LDTP09881 8.40  LDD1827 
TATA-binding protein-associated factor 2N (TAF15) LDTP09881 8.40  LDD1827 
Testis-expressed protein 264 (TEX264) LDTP14259 8.57  LDD1827 
Testis-expressed protein 264 (TEX264) LDTP14259 8.57  LDD1827 
Tetraspanin-6 (TSPAN6) LDTP14458 8.94  LDD1827 
Tetraspanin-6 (TSPAN6) LDTP14458 8.94  LDD1827 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 9.32  LDD1827 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 9.32  LDD1827 
Tetratricopeptide repeat protein 21B (TTC21B) LDTP08073 8.75  LDD1827 
Tetratricopeptide repeat protein 21B (TTC21B) LDTP08073 8.75  LDD1827 
Tetratricopeptide repeat protein 38 (TTC38) LDTP19372 41.93  LDD1827 
Tetratricopeptide repeat protein 38 (TTC38) LDTP19372 41.93  LDD1827 
Ubiquinol-cytochrome c reductase complex assembly factor 5 (UQCC5) LDTP15634 11.79  LDD1827 
Ubiquinol-cytochrome c reductase complex assembly factor 5 (UQCC5) LDTP15634 11.79  LDD1827 
Ubiquitin-associated protein 2-like (UBAP2L) LDTP06060 9.25  LDD1827 
Ubiquitin-associated protein 2-like (UBAP2L) LDTP06060 9.25  LDD1827 
Vimentin (VIM) LDTP02297 9.58  LDD1827 
Vimentin (VIM) LDTP02297 9.58  LDD1827 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1827 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587