General Information of Experiment

Probe Name AEA-DA  Probe Info 
Probe concentration 10 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
SILAC
Competitor Name SR-4559  Competitor Info 
Competitor Concentration 25 uM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 10 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP09542  1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (ABHD5) 15.8
 LDTP12628  Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) 11.7
 LDTP12056  Thiol S-methyltransferase TMT1A (TMT1A) 8.4
 LDTP05758  S-methyl-5'-thioadenosine phosphorylase (MTAP) 7.8
 LDTP10329  Ceramide synthase 2 (CERS2) 5.0
 LDTP06849  Prolyl endopeptidase-like (PREPL) 4.7
 LDTP03769  Sterol O-acyltransferase 1 (SOAT1) 3.7
 LDTP10550  Dehydrogenase/reductase SDR family member 1 (DHRS1) 3.4
 LDTP01419  Retinal dehydrogenase 2 (ALDH1A2) 3.3
 LDTP16007  Lipid droplet-associated hydrolase (LDAH) 3.1
Other
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP07906  Mediator of RNA polymerase II transcription subunit 25 (MED25) 5.2

References

1 Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics. ACS Chem Biol. 2017 Oct 20;12(10):2671-2681. doi: 10.1021/acschembio.7b00581. Epub 2017 Sep 20.
Mass spectrometry data entry: PXD007570