Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | AEA-DA | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | 5 uM | |||||
| Criteria | Quantification: Probe vs (Probe+Competitor) | |||||
| Quantitative Method |
SILAC
|
|||||
| Competitor Name | FK866 | Competitor Info | ||||
| Competitor Concentration | 25 uM | |||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Lung | ||||
| Disease Model | Lung adenocarcinoma [ICD-11:2C25] | |||||
| Model Name | Human lung adenocarcinoma cells (A-549) | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP03692 | Bifunctional epoxide hydrolase 2 (EPHX2) | 20.0 | ||||
| LDTP10550 | Dehydrogenase/reductase SDR family member 1 (DHRS1) | 20.0 | ||||
| LDTP04051 | Nicotinamide phosphoribosyltransferase (NAMPT) | 20.0 | ||||
| LDTP03198 | Ferrochelatase, mitochondrial (FECH) | 13.7 | ||||
| LDTP05436 | Aldo-keto reductase family 1 member C1 (AKR1C1) | 9.3 | ||||
| LDTP04543 | Aldo-keto reductase family 1 member C2 (AKR1C2) | 9.2 | ||||
| LDTP15484 | Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) | 8.1 | ||||
| LDTP01767 | Aldehyde dehydrogenase 1A1 (ALDH1A1) | 7.6 | ||||
| LDTP03976 | Aldo-keto reductase family 1 member C3 (AKR1C3) | 6.0 | ||||
| LDTP08979 | Prostaglandin reductase 2 (PTGR2) | 5.1 | ||||
| LDTP06333 | Serum paraoxonase/arylesterase 2 (PON2) | 2.9 | ||||
| LDTP12267 | Cytochrome P450 4F12 (CYP4F12) | 2.4 | ||||
| LDTP03257 | Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) | 2.3 | ||||