Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name AEA-DA  Probe Info 
Probe concentration 10 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
SILAC
Competitor Name SR-4995  Competitor Info 
Competitor Concentration 25 uM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 4 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03692  Bifunctional epoxide hydrolase 2 (EPHX2) 20.0
 LDTP09542  1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (ABHD5) 15.3
 LDTP02254  ATP-dependent translocase ABCB1 (ABCB1) 4.2
 LDTP10550  Dehydrogenase/reductase SDR family member 1 (DHRS1) 3.1
Transporter and channel
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP09547  Scavenger receptor class B member 1 (SCARB1) 3.5
 LDTP14511  ATP synthase subunit g, mitochondrial (ATP5MG) 3.1

References

1 Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics. ACS Chem Biol. 2017 Oct 20;12(10):2671-2681. doi: 10.1021/acschembio.7b00581. Epub 2017 Sep 20.
Mass spectrometry data entry: PXD007570