General Information of Experiment

Probe Name C172  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 4 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP00697  Cytochrome b5 type B (CYB5B) 17.8
 LDTP03540  Heme oxygenase 2 (HMOX2) 6.9
 LDTP03257  Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) 5.4
 LDTP01328  CAAX prenyl protease 1 homolog (ZMPSTE24) 5.3
Transporter and channel
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP08878  ER membrane protein complex subunit 5 (MMGT1) 6.1
 LDTP04033  Translocon-associated protein subunit alpha (SSR1) 5.9
 LDTP10913  Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) 5.9
Other
Click to Show/Hide to Show 8 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP12565  Mitochondrial import receptor subunit TOM22 homolog (TOMM22) 9.7
 LDTP13902  Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) 9.1
 LDTP15420  Mitochondrial import receptor subunit TOM5 homolog (TOMM5) 8.2
 LDTP01522  Reticulon-3 (RTN3) 7.3
 LDTP16006  Optic atrophy 3 protein (OPA3) 5.5
 LDTP13828  Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) 5.4
 LDTP08594  Negative elongation factor C/D (NELFCD) 5.0
 LDTP03678  ER lumen protein-retaining receptor 2 (KDELR2) 4.9

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587