Details of the Target

General Information of Target

Target ID LDTP15002
Target Name Armadillo-like helical domain-containing protein 3 (ARMH3)
Gene Name ARMH3
Gene ID 79591
Synonyms
C10orf76; Armadillo-like helical domain-containing protein 3
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSRPAHRRPEYHKINKDLFVLTYGALVAQLCKDYEKDEDVNQYLDKMGYGIGTRLVEDFL
ARSCVGRCHSYSEIIDIIAQVAFKMYLGITPSVTCNNSSKNEFSLILEKNPLVEFVEELP
AGRSSLCYCNLLCGIIRGALEMVHLAADVTFLQDRLKGDSVTEIGITFLKKRDEKKYRGK
K
Target Bioclass
Other
Family
ARMH3 family
Subcellular location
Golgi apparatus membrane
Function Involved in GBF1 recruitment, Golgi maintenance and protein secretion.
Uniprot ID
Q5T2E6
Ensemble ID
ENST00000370033.9
HGNC ID
HGNC:25788

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
HCT15 SNV: p.A317V; p.P442S; p.E644G .
HEC1 SNV: p.F673V DBIA    Probe Info 
HEC1B SNV: p.F673V .
IM95 SNV: p.R44Q DBIA    Probe Info 
KYSE180 SNV: p.T343S .
NCIH661 SNV: p.R645L .
OVK18 SNV: p.M416T DBIA    Probe Info 
SNU449 SNV: p.Y481C .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 10 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K657(0.39)  LDD0277  [1]
Probe 1
 Probe Info  		Y643(19.98)  LDD3495  [2]
AHL-Pu-1
 Probe Info  		C105(3.17)  LDD0168  [3]
DBIA
 Probe Info  		C105(0.79); C80(0.97); C85(1.07)  LDD0531  [4]
4-Iodoacetamidophenylacetylene
 Probe Info  		N.A.  LDD0038  [5]
IA-alkyne
 Probe Info  		N.A.  LDD0036  [5]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [5]
IPM
 Probe Info  		C105(0.00); C80(0.00); C149(0.00)  LDD2156  [6]
AOyne
 Probe Info  		12.40  LDD0443  [7]
NAIA_5
 Probe Info  		N.A.  LDD2223  [8]
PAL-AfBPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C293
 Probe Info  		41.36  LDD1963  [9]
VE-P
 Probe Info  		N.A.  LDD0396  [10]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA HEK-293T C105(3.17)  LDD0168  [3]
 LDCM0214  AC1 HCT 116 C105(0.79); C80(0.97); C85(1.07)  LDD0531  [4]
 LDCM0215  AC10 HCT 116 C105(0.82); C80(1.20); C85(1.20)  LDD0532  [4]
 LDCM0216  AC100 HCT 116 C80(0.78); C85(0.78)  LDD0533  [4]
 LDCM0217  AC101 HCT 116 C80(0.79); C85(0.79)  LDD0534  [4]
 LDCM0218  AC102 HCT 116 C80(0.86); C85(0.86)  LDD0535  [4]
 LDCM0219  AC103 HCT 116 C80(0.64); C85(0.64)  LDD0536  [4]
 LDCM0220  AC104 HCT 116 C80(0.69); C85(0.69)  LDD0537  [4]
 LDCM0221  AC105 HCT 116 C80(0.87); C85(0.87)  LDD0538  [4]
 LDCM0222  AC106 HCT 116 C80(0.74); C85(0.74)  LDD0539  [4]
 LDCM0223  AC107 HCT 116 C80(0.95); C85(0.49)  LDD0540  [4]
 LDCM0224  AC108 HCT 116 C80(0.54); C85(2.20)  LDD0541  [4]
 LDCM0225  AC109 HCT 116 C80(0.56); C85(2.01)  LDD0542  [4]
 LDCM0226  AC11 HCT 116 C105(0.92); C80(0.76); C85(0.76)  LDD0543  [4]
 LDCM0227  AC110 HCT 116 C80(0.80); C85(1.58)  LDD0544  [4]
 LDCM0228  AC111 HCT 116 C80(0.65); C85(1.64)  LDD0545  [4]
 LDCM0229  AC112 HCT 116 C80(0.85); C85(1.24)  LDD0546  [4]
 LDCM0230  AC113 HCT 116 C80(1.06); C85(1.06)  LDD0547  [4]
 LDCM0231  AC114 HCT 116 C80(0.79); C85(0.96)  LDD0548  [4]
 LDCM0232  AC115 HCT 116 C80(0.94); C85(0.99)  LDD0549  [4]
 LDCM0233  AC116 HCT 116 C80(0.93); C85(1.04)  LDD0550  [4]
 LDCM0234  AC117 HCT 116 C80(0.93); C85(1.33)  LDD0551  [4]
 LDCM0235  AC118 HCT 116 C80(1.12); C85(1.09)  LDD0552  [4]
 LDCM0236  AC119 HCT 116 C80(0.92); C85(1.09)  LDD0553  [4]
 LDCM0237  AC12 HCT 116 C105(0.99); C80(1.07); C85(1.07)  LDD0554  [4]
 LDCM0238  AC120 HCT 116 C80(0.98); C85(0.85)  LDD0555  [4]
 LDCM0239  AC121 HCT 116 C80(0.97); C85(1.27)  LDD0556  [4]
 LDCM0240  AC122 HCT 116 C80(0.87); C85(0.96)  LDD0557  [4]
 LDCM0241  AC123 HCT 116 C80(0.82); C85(1.71)  LDD0558  [4]
 LDCM0242  AC124 HCT 116 C80(1.04); C85(0.98)  LDD0559  [4]
 LDCM0243  AC125 HCT 116 C80(0.99); C85(1.00)  LDD0560  [4]
 LDCM0244  AC126 HCT 116 C80(0.91); C85(0.98)  LDD0561  [4]
 LDCM0245  AC127 HCT 116 C80(1.24); C85(1.05)  LDD0562  [4]
 LDCM0246  AC128 HEK-293T C80(0.65); C85(0.65)  LDD0844  [4]
 LDCM0247  AC129 HEK-293T C80(0.65); C85(0.65)  LDD0845  [4]
 LDCM0249  AC130 HEK-293T C80(0.87); C85(0.87)  LDD0847  [4]
 LDCM0250  AC131 HEK-293T C80(0.78); C85(0.78)  LDD0848  [4]
 LDCM0251  AC132 HEK-293T C80(0.98); C85(0.98)  LDD0849  [4]
 LDCM0252  AC133 HEK-293T C80(0.73); C85(0.73)  LDD0850  [4]
 LDCM0253  AC134 HEK-293T C80(0.96); C85(0.96)  LDD0851  [4]
 LDCM0254  AC135 HEK-293T C80(1.11); C85(1.11)  LDD0852  [4]
 LDCM0255  AC136 HEK-293T C80(1.10); C85(1.10)  LDD0853  [4]
 LDCM0256  AC137 HEK-293T C80(0.76); C85(0.76)  LDD0854  [4]
 LDCM0257  AC138 HEK-293T C80(0.84); C85(0.84)  LDD0855  [4]
 LDCM0258  AC139 HEK-293T C80(0.74); C85(0.74)  LDD0856  [4]
 LDCM0259  AC14 HCT 116 C105(0.70); C80(1.17); C85(1.17)  LDD0576  [4]
 LDCM0260  AC140 HEK-293T C80(0.82); C85(0.82)  LDD0858  [4]
 LDCM0261  AC141 HEK-293T C80(0.69); C85(0.69)  LDD0859  [4]
 LDCM0262  AC142 HEK-293T C80(0.83); C85(0.83)  LDD0860  [4]
 LDCM0263  AC143 PaTu 8988t C105(0.93)  LDD1142  [4]
 LDCM0264  AC144 PaTu 8988t C105(1.04)  LDD1143  [4]
 LDCM0265  AC145 PaTu 8988t C105(0.92)  LDD1144  [4]
 LDCM0266  AC146 PaTu 8988t C105(1.12)  LDD1145  [4]
 LDCM0267  AC147 PaTu 8988t C105(0.97)  LDD1146  [4]
 LDCM0268  AC148 PaTu 8988t C105(0.95)  LDD1147  [4]
 LDCM0269  AC149 PaTu 8988t C105(1.09)  LDD1148  [4]
 LDCM0270  AC15 HCT 116 C105(0.87); C80(1.09); C85(1.09)  LDD0587  [4]
 LDCM0271  AC150 PaTu 8988t C105(0.95)  LDD1150  [4]
 LDCM0272  AC151 PaTu 8988t C105(0.97)  LDD1151  [4]
 LDCM0273  AC152 PaTu 8988t C105(1.15)  LDD1152  [4]
 LDCM0274  AC153 PaTu 8988t C105(1.06)  LDD1153  [4]
 LDCM0621  AC154 PaTu 8988t C105(1.11)  LDD2166  [4]
 LDCM0622  AC155 PaTu 8988t C105(0.95)  LDD2167  [4]
 LDCM0623  AC156 PaTu 8988t C105(0.94)  LDD2168  [4]
 LDCM0624  AC157 PaTu 8988t C105(1.07)  LDD2169  [4]
 LDCM0276  AC17 HCT 116 C80(0.88); C85(0.88)  LDD0593  [4]
 LDCM0277  AC18 HCT 116 C80(0.92); C85(0.92)  LDD0594  [4]
 LDCM0278  AC19 HCT 116 C80(0.95); C85(0.95)  LDD0595  [4]
 LDCM0279  AC2 HCT 116 C105(0.90); C80(1.24); C85(1.31)  LDD0596  [4]
 LDCM0280  AC20 HCT 116 C80(0.90); C85(0.90)  LDD0597  [4]
 LDCM0281  AC21 HCT 116 C80(0.78); C85(0.78)  LDD0598  [4]
 LDCM0282  AC22 HCT 116 C80(0.82); C85(0.82)  LDD0599  [4]
 LDCM0283  AC23 HCT 116 C80(0.77); C85(0.77)  LDD0600  [4]
 LDCM0284  AC24 HCT 116 C80(0.93); C85(0.93)  LDD0601  [4]
 LDCM0285  AC25 HEK-293T C85(0.86)  LDD0883  [4]
 LDCM0286  AC26 HEK-293T C85(0.86)  LDD0884  [4]
 LDCM0287  AC27 HEK-293T C85(0.90)  LDD0885  [4]
 LDCM0288  AC28 HEK-293T C85(0.87)  LDD0886  [4]
 LDCM0289  AC29 HEK-293T C85(0.96)  LDD0887  [4]
 LDCM0290  AC3 HCT 116 C105(0.87); C80(1.19); C85(1.20)  LDD0607  [4]
 LDCM0291  AC30 HEK-293T C85(0.88)  LDD0889  [4]
 LDCM0292  AC31 HEK-293T C85(0.75)  LDD0890  [4]
 LDCM0293  AC32 HEK-293T C85(0.81)  LDD0891  [4]
 LDCM0294  AC33 HEK-293T C85(0.93)  LDD0892  [4]
 LDCM0295  AC34 HEK-293T C85(0.87)  LDD0893  [4]
 LDCM0296  AC35 PaTu 8988t C80(0.70); C85(0.70); C105(0.83)  LDD1175  [4]
 LDCM0297  AC36 PaTu 8988t C80(0.67); C85(0.67); C105(0.69)  LDD1176  [4]
 LDCM0298  AC37 PaTu 8988t C80(0.77); C85(0.77); C105(0.76)  LDD1177  [4]
 LDCM0299  AC38 PaTu 8988t C80(0.73); C85(0.73); C105(0.69)  LDD1178  [4]
 LDCM0300  AC39 PaTu 8988t C80(0.61); C85(0.61); C105(0.70)  LDD1179  [4]
 LDCM0301  AC4 HCT 116 C105(0.79); C80(1.11); C85(1.26)  LDD0618  [4]
 LDCM0302  AC40 PaTu 8988t C80(0.69); C85(0.69); C105(0.71)  LDD1181  [4]
 LDCM0303  AC41 PaTu 8988t C80(0.85); C85(0.85); C105(0.79)  LDD1182  [4]
 LDCM0304  AC42 PaTu 8988t C80(1.20); C85(1.20); C105(0.79)  LDD1183  [4]
 LDCM0305  AC43 PaTu 8988t C80(0.67); C85(0.67); C105(0.81)  LDD1184  [4]
 LDCM0306  AC44 PaTu 8988t C80(0.95); C85(0.95); C105(0.69)  LDD1185  [4]
 LDCM0307  AC45 PaTu 8988t C80(0.94); C85(0.94); C105(0.70)  LDD1186  [4]
 LDCM0308  AC46 HCT 116 C80(0.92); C85(0.92)  LDD0625  [4]
 LDCM0309  AC47 HCT 116 C80(0.64); C85(0.64)  LDD0626  [4]
 LDCM0310  AC48 HCT 116 C80(0.53); C85(0.53)  LDD0627  [4]
 LDCM0311  AC49 HCT 116 C80(0.81); C85(0.81)  LDD0628  [4]
 LDCM0312  AC5 HCT 116 C105(0.81); C85(1.10); C80(1.13)  LDD0629  [4]
 LDCM0313  AC50 HCT 116 C80(0.71); C85(0.71)  LDD0630  [4]
 LDCM0314  AC51 HCT 116 C80(0.89); C85(0.89)  LDD0631  [4]
 LDCM0315  AC52 HCT 116 C80(0.75); C85(0.75)  LDD0632  [4]
 LDCM0316  AC53 HCT 116 C80(0.91); C85(0.91)  LDD0633  [4]
 LDCM0317  AC54 HCT 116 C80(0.97); C85(0.97)  LDD0634  [4]
 LDCM0318  AC55 HCT 116 C80(0.96); C85(0.96)  LDD0635  [4]
 LDCM0319  AC56 HCT 116 C80(0.95); C85(0.95)  LDD0636  [4]
 LDCM0320  AC57 HEK-293T C80(0.96); C85(1.44)  LDD0918  [4]
 LDCM0321  AC58 HEK-293T C80(1.36); C85(1.24)  LDD0919  [4]
 LDCM0322  AC59 HEK-293T C80(1.12); C85(1.15)  LDD0920  [4]
 LDCM0323  AC6 HCT 116 C105(1.06); C80(1.08); C85(1.08)  LDD0640  [4]
 LDCM0324  AC60 HEK-293T C80(0.83); C85(0.92)  LDD0922  [4]
 LDCM0325  AC61 HEK-293T C80(1.53); C85(1.51)  LDD0923  [4]
 LDCM0326  AC62 HEK-293T C80(1.17); C85(1.32)  LDD0924  [4]
 LDCM0327  AC63 HEK-293T C80(1.05); C85(1.19)  LDD0925  [4]
 LDCM0328  AC64 HEK-293T C80(1.30); C85(1.25)  LDD0926  [4]
 LDCM0329  AC65 HEK-293T C80(1.42); C85(1.29)  LDD0927  [4]
 LDCM0330  AC66 HEK-293T C80(1.57); C85(1.50)  LDD0928  [4]
 LDCM0331  AC67 HEK-293T C80(1.54); C85(1.44)  LDD0929  [4]
 LDCM0332  AC68 HCT 116 C80(1.02); C85(1.02)  LDD0649  [4]
 LDCM0333  AC69 HCT 116 C80(1.01); C85(1.01)  LDD0650  [4]
 LDCM0334  AC7 HCT 116 C105(0.79); C80(0.83); C85(0.83)  LDD0651  [4]
 LDCM0335  AC70 HCT 116 C80(0.74); C85(0.74)  LDD0652  [4]
 LDCM0336  AC71 HCT 116 C80(1.09); C85(1.09)  LDD0653  [4]
 LDCM0337  AC72 HCT 116 C80(0.98); C85(0.98)  LDD0654  [4]
 LDCM0338  AC73 HCT 116 C80(0.95); C85(0.95)  LDD0655  [4]
 LDCM0339  AC74 HCT 116 C80(1.02); C85(1.02)  LDD0656  [4]
 LDCM0340  AC75 HCT 116 C80(0.92); C85(0.92)  LDD0657  [4]
 LDCM0341  AC76 HCT 116 C80(0.95); C85(0.95)  LDD0658  [4]
 LDCM0342  AC77 HCT 116 C80(0.92); C85(0.92)  LDD0659  [4]
 LDCM0343  AC78 HCT 116 C80(1.02); C85(1.02)  LDD0660  [4]
 LDCM0344  AC79 HCT 116 C80(1.02); C85(1.02)  LDD0661  [4]
 LDCM0345  AC8 HCT 116 C105(0.79); C80(0.83); C85(0.83)  LDD0662  [4]
 LDCM0346  AC80 HCT 116 C80(1.08); C85(1.08)  LDD0663  [4]
 LDCM0347  AC81 HCT 116 C80(1.17); C85(1.17)  LDD0664  [4]
 LDCM0348  AC82 HCT 116 C80(0.94); C85(0.94)  LDD0665  [4]
 LDCM0349  AC83 HEK-293T C80(0.91); C85(0.91)  LDD0947  [4]
 LDCM0350  AC84 HEK-293T C80(0.87); C85(0.87)  LDD0948  [4]
 LDCM0351  AC85 HEK-293T C80(0.68); C85(0.68)  LDD0949  [4]
 LDCM0352  AC86 HEK-293T C80(0.99); C85(0.99)  LDD0950  [4]
 LDCM0353  AC87 HEK-293T C80(0.78); C85(0.78)  LDD0951  [4]
 LDCM0354  AC88 HEK-293T C80(0.66); C85(0.66)  LDD0952  [4]
 LDCM0355  AC89 HEK-293T C80(0.72); C85(0.72)  LDD0953  [4]
 LDCM0357  AC90 HEK-293T C80(0.84); C85(0.84)  LDD0955  [4]
 LDCM0358  AC91 HEK-293T C80(1.17); C85(1.17)  LDD0956  [4]
 LDCM0359  AC92 HEK-293T C80(0.92); C85(0.92)  LDD0957  [4]
 LDCM0360  AC93 HEK-293T C80(0.90); C85(0.90)  LDD0958  [4]
 LDCM0361  AC94 HEK-293T C80(1.00); C85(1.00)  LDD0959  [4]
 LDCM0362  AC95 HEK-293T C80(1.16); C85(1.16)  LDD0960  [4]
 LDCM0363  AC96 HEK-293T C80(0.78); C85(0.78)  LDD0961  [4]
 LDCM0364  AC97 HEK-293T C80(1.54); C85(1.54)  LDD0962  [4]
 LDCM0365  AC98 HCT 116 C80(0.71); C85(0.71)  LDD0682  [4]
 LDCM0366  AC99 HCT 116 C80(0.68); C85(0.68)  LDD0683  [4]
 LDCM0248  AKOS034007472 HCT 116 C105(1.00); C80(0.98); C85(0.98)  LDD0565  [4]
 LDCM0356  AKOS034007680 HCT 116 C105(0.91); C80(1.10); C85(1.10)  LDD0673  [4]
 LDCM0275  AKOS034007705 HCT 116 C105(0.89); C80(0.99); C85(0.99)  LDD0592  [4]
 LDCM0632  CL-Sc Hep-G2 C105(0.39)  LDD2227  [8]
 LDCM0367  CL1 PaTu 8988t C80(0.90); C85(0.90); C105(1.03)  LDD1246  [4]
 LDCM0368  CL10 PaTu 8988t C80(0.83); C85(0.83); C105(0.81)  LDD1247  [4]
 LDCM0369  CL100 HCT 116 C105(0.82); C80(1.08); C85(1.16)  LDD0686  [4]
 LDCM0370  CL101 HCT 116 C105(0.98); C80(1.13); C85(1.13)  LDD0687  [4]
 LDCM0371  CL102 HCT 116 C105(1.01); C80(1.01); C85(1.01)  LDD0688  [4]
 LDCM0372  CL103 HCT 116 C80(0.98); C85(0.98); C105(0.98)  LDD0689  [4]
 LDCM0373  CL104 HCT 116 C80(0.96); C85(0.96); C105(1.08)  LDD0690  [4]
 LDCM0374  CL105 HCT 116 C80(0.71); C85(0.71)  LDD0691  [4]
 LDCM0375  CL106 HCT 116 C80(0.69); C85(0.69)  LDD0692  [4]
 LDCM0376  CL107 HCT 116 C80(0.79); C85(0.79)  LDD0693  [4]
 LDCM0377  CL108 HCT 116 C80(0.83); C85(0.83)  LDD0694  [4]
 LDCM0378  CL109 HCT 116 C80(0.88); C85(0.88)  LDD0695  [4]
 LDCM0379  CL11 PaTu 8988t C80(0.84); C85(0.84); C105(0.75)  LDD1258  [4]
 LDCM0380  CL110 HCT 116 C80(1.02); C85(1.02)  LDD0697  [4]
 LDCM0381  CL111 HCT 116 C80(0.93); C85(0.93)  LDD0698  [4]
 LDCM0382  CL112 HEK-293T C85(0.79)  LDD0980  [4]
 LDCM0383  CL113 HEK-293T C85(0.79)  LDD0981  [4]
 LDCM0384  CL114 HEK-293T C85(1.06)  LDD0982  [4]
 LDCM0385  CL115 HEK-293T C85(0.94)  LDD0983  [4]
 LDCM0386  CL116 HEK-293T C85(0.96)  LDD0984  [4]
 LDCM0387  CL117 PaTu 8988t C80(0.89); C85(0.89); C105(0.83)  LDD1266  [4]
 LDCM0388  CL118 PaTu 8988t C80(0.91); C85(0.91); C105(0.80)  LDD1267  [4]
 LDCM0389  CL119 PaTu 8988t C80(1.06); C85(1.06); C105(0.75)  LDD1268  [4]
 LDCM0390  CL12 PaTu 8988t C80(0.94); C85(0.94); C105(0.98)  LDD1269  [4]
 LDCM0391  CL120 PaTu 8988t C80(0.83); C85(0.83); C105(0.72)  LDD1270  [4]
 LDCM0392  CL121 HCT 116 C80(1.17); C85(1.17)  LDD0709  [4]
 LDCM0393  CL122 HCT 116 C80(1.02); C85(1.02)  LDD0710  [4]
 LDCM0394  CL123 HCT 116 C80(0.78); C85(0.78)  LDD0711  [4]
 LDCM0395  CL124 HCT 116 C80(0.81); C85(0.81)  LDD0712  [4]
 LDCM0396  CL125 HEK-293T C80(1.01); C85(1.01)  LDD0994  [4]
 LDCM0397  CL126 HEK-293T C80(0.76); C85(0.84)  LDD0995  [4]
 LDCM0398  CL127 HEK-293T C80(1.17); C85(1.02)  LDD0996  [4]
 LDCM0399  CL128 HEK-293T C80(1.38); C85(1.28)  LDD0997  [4]
 LDCM0400  CL13 PaTu 8988t C80(0.76); C85(0.76); C105(0.98)  LDD1279  [4]
 LDCM0401  CL14 PaTu 8988t C80(1.16); C85(1.16); C105(1.16)  LDD1280  [4]
 LDCM0402  CL15 PaTu 8988t C80(0.87); C85(0.87); C105(0.89)  LDD1281  [4]
 LDCM0403  CL16 PaTu 8988t C80(0.75); C85(0.75)  LDD1282  [4]
 LDCM0404  CL17 PaTu 8988t C80(0.76); C85(0.76)  LDD1283  [4]
 LDCM0405  CL18 PaTu 8988t C80(1.03); C85(1.03)  LDD1284  [4]
 LDCM0406  CL19 PaTu 8988t C80(1.14); C85(1.14)  LDD1285  [4]
 LDCM0407  CL2 PaTu 8988t C80(0.96); C85(0.96); C105(0.85)  LDD1286  [4]
 LDCM0408  CL20 PaTu 8988t C80(0.75); C85(0.75)  LDD1287  [4]
 LDCM0409  CL21 PaTu 8988t C80(1.06); C85(1.06)  LDD1288  [4]
 LDCM0410  CL22 PaTu 8988t C80(0.98); C85(0.98)  LDD1289  [4]
 LDCM0411  CL23 PaTu 8988t C80(1.29); C85(1.29)  LDD1290  [4]
 LDCM0412  CL24 PaTu 8988t C80(0.69); C85(0.69)  LDD1291  [4]
 LDCM0413  CL25 PaTu 8988t C80(0.73); C85(0.73)  LDD1292  [4]
 LDCM0414  CL26 PaTu 8988t C80(0.75); C85(0.75)  LDD1293  [4]
 LDCM0415  CL27 PaTu 8988t C80(1.12); C85(1.12)  LDD1294  [4]
 LDCM0416  CL28 PaTu 8988t C80(0.82); C85(0.82)  LDD1295  [4]
 LDCM0417  CL29 PaTu 8988t C80(0.82); C85(0.82)  LDD1296  [4]
 LDCM0418  CL3 PaTu 8988t C80(0.65); C85(0.65); C105(0.78)  LDD1297  [4]
 LDCM0419  CL30 PaTu 8988t C80(0.99); C85(0.99)  LDD1298  [4]
 LDCM0420  CL31 HCT 116 C105(0.89)  LDD0737  [4]
 LDCM0421  CL32 HCT 116 C105(0.81)  LDD0738  [4]
 LDCM0422  CL33 HCT 116 C105(0.77)  LDD0739  [4]
 LDCM0423  CL34 HCT 116 C105(0.91)  LDD0740  [4]
 LDCM0424  CL35 HCT 116 C105(0.94)  LDD0741  [4]
 LDCM0425  CL36 HCT 116 C105(0.99)  LDD0742  [4]
 LDCM0426  CL37 HCT 116 C105(0.89)  LDD0743  [4]
 LDCM0428  CL39 HCT 116 C105(0.94)  LDD0745  [4]
 LDCM0429  CL4 PaTu 8988t C80(0.81); C85(0.81); C105(0.81)  LDD1308  [4]
 LDCM0430  CL40 HCT 116 C105(0.94)  LDD0747  [4]
 LDCM0431  CL41 HCT 116 C105(0.85)  LDD0748  [4]
 LDCM0432  CL42 HCT 116 C105(0.96)  LDD0749  [4]
 LDCM0433  CL43 HCT 116 C105(0.93)  LDD0750  [4]
 LDCM0434  CL44 HCT 116 C105(0.80)  LDD0751  [4]
 LDCM0435  CL45 HCT 116 C105(0.77)  LDD0752  [4]
 LDCM0436  CL46 HCT 116 C80(0.80)  LDD0753  [4]
 LDCM0437  CL47 HCT 116 C80(0.88)  LDD0754  [4]
 LDCM0438  CL48 HCT 116 C80(0.78)  LDD0755  [4]
 LDCM0439  CL49 HCT 116 C80(0.80)  LDD0756  [4]
 LDCM0440  CL5 PaTu 8988t C80(1.00); C85(1.00); C105(0.90)  LDD1319  [4]
 LDCM0441  CL50 HCT 116 C80(0.98)  LDD0758  [4]
 LDCM0442  CL51 HCT 116 C80(1.00)  LDD0759  [4]
 LDCM0443  CL52 HCT 116 C80(0.85)  LDD0760  [4]
 LDCM0444  CL53 HCT 116 C80(1.43)  LDD0761  [4]
 LDCM0445  CL54 HCT 116 C80(0.89)  LDD0762  [4]
 LDCM0446  CL55 HCT 116 C80(0.89)  LDD0763  [4]
 LDCM0447  CL56 HCT 116 C80(1.07)  LDD0764  [4]
 LDCM0448  CL57 HCT 116 C80(1.00)  LDD0765  [4]
 LDCM0449  CL58 HCT 116 C80(0.78)  LDD0766  [4]
 LDCM0450  CL59 HCT 116 C80(0.85)  LDD0767  [4]
 LDCM0451  CL6 PaTu 8988t C80(0.98); C85(0.98); C105(0.96)  LDD1330  [4]
 LDCM0452  CL60 HCT 116 C80(0.82)  LDD0769  [4]
 LDCM0453  CL61 HCT 116 C80(1.04)  LDD0770  [4]
 LDCM0454  CL62 HCT 116 C80(0.98)  LDD0771  [4]
 LDCM0455  CL63 HCT 116 C80(1.04)  LDD0772  [4]
 LDCM0456  CL64 HCT 116 C80(1.12)  LDD0773  [4]
 LDCM0457  CL65 HCT 116 C80(0.99)  LDD0774  [4]
 LDCM0458  CL66 HCT 116 C80(1.03)  LDD0775  [4]
 LDCM0459  CL67 HCT 116 C80(1.17)  LDD0776  [4]
 LDCM0460  CL68 HCT 116 C80(1.22)  LDD0777  [4]
 LDCM0461  CL69 HCT 116 C80(1.03)  LDD0778  [4]
 LDCM0462  CL7 PaTu 8988t C80(0.76); C85(0.76); C105(0.97)  LDD1341  [4]
 LDCM0463  CL70 HCT 116 C80(0.81)  LDD0780  [4]
 LDCM0464  CL71 HCT 116 C80(0.98)  LDD0781  [4]
 LDCM0465  CL72 HCT 116 C80(0.94)  LDD0782  [4]
 LDCM0466  CL73 HCT 116 C80(1.15)  LDD0783  [4]
 LDCM0467  CL74 HCT 116 C80(1.25)  LDD0784  [4]
 LDCM0469  CL76 HCT 116 C105(0.85)  LDD0786  [4]
 LDCM0470  CL77 HCT 116 C105(1.00)  LDD0787  [4]
 LDCM0471  CL78 HCT 116 C105(1.00)  LDD0788  [4]
 LDCM0472  CL79 HCT 116 C105(1.09)  LDD0789  [4]
 LDCM0473  CL8 PaTu 8988t C80(0.69); C85(0.69); C105(0.84)  LDD1352  [4]
 LDCM0474  CL80 HCT 116 C105(0.90)  LDD0791  [4]
 LDCM0475  CL81 HCT 116 C105(0.99)  LDD0792  [4]
 LDCM0476  CL82 HCT 116 C105(1.08)  LDD0793  [4]
 LDCM0477  CL83 HCT 116 C105(1.07)  LDD0794  [4]
 LDCM0478  CL84 HCT 116 C105(1.19)  LDD0795  [4]
 LDCM0479  CL85 HCT 116 C105(1.02)  LDD0796  [4]
 LDCM0480  CL86 HCT 116 C105(1.07)  LDD0797  [4]
 LDCM0481  CL87 HCT 116 C105(1.12)  LDD0798  [4]
 LDCM0482  CL88 HCT 116 C105(1.06)  LDD0799  [4]
 LDCM0483  CL89 HCT 116 C105(1.26)  LDD0800  [4]
 LDCM0484  CL9 PaTu 8988t C80(0.92); C85(0.92); C105(0.66)  LDD1363  [4]
 LDCM0485  CL90 HCT 116 C105(1.05)  LDD0802  [4]
 LDCM0486  CL91 HCT 116 C105(0.86); C80(0.96); C85(1.02)  LDD0803  [4]
 LDCM0487  CL92 HCT 116 C105(0.94); C80(1.02); C85(0.95)  LDD0804  [4]
 LDCM0488  CL93 HCT 116 C105(0.94); C80(0.97); C85(1.00)  LDD0805  [4]
 LDCM0489  CL94 HCT 116 C105(0.81); C80(1.26); C85(1.30)  LDD0806  [4]
 LDCM0490  CL95 HCT 116 C105(0.89); C80(1.10); C85(1.08)  LDD0807  [4]
 LDCM0491  CL96 HCT 116 C105(0.85); C80(1.00); C85(1.05)  LDD0808  [4]
 LDCM0492  CL97 HCT 116 C105(0.93); C80(1.14); C85(0.89)  LDD0809  [4]
 LDCM0493  CL98 HCT 116 C105(0.87); C80(1.05); C85(1.01)  LDD0810  [4]
 LDCM0494  CL99 HCT 116 C105(0.87); C80(1.04); C85(1.10)  LDD0811  [4]
 LDCM0495  E2913 HEK-293T C149(1.07); C105(1.08)  LDD1698  [11]
 LDCM0625  F8 Ramos C471(0.76)  LDD2187  [12]
 LDCM0572  Fragment10 Ramos C471(0.43)  LDD2189  [12]
 LDCM0573  Fragment11 Ramos C105(1.63)  LDD2190  [12]
 LDCM0574  Fragment12 Ramos C471(0.63)  LDD2191  [12]
 LDCM0576  Fragment14 Ramos C105(1.88)  LDD2193  [12]
 LDCM0579  Fragment20 Ramos C471(1.08)  LDD2194  [12]
 LDCM0580  Fragment21 Ramos C471(0.50)  LDD2195  [12]
 LDCM0582  Fragment23 Ramos C471(0.85)  LDD2196  [12]
 LDCM0578  Fragment27 Ramos C471(0.78)  LDD2197  [12]
 LDCM0586  Fragment28 Ramos C471(3.00); C105(0.41)  LDD2198  [12]
 LDCM0589  Fragment31 Ramos C471(1.09)  LDD2200  [12]
 LDCM0590  Fragment32 Ramos C471(0.52)  LDD2201  [12]
 LDCM0468  Fragment33 HCT 116 C80(1.09)  LDD0785  [4]
 LDCM0596  Fragment38 Ramos C471(0.37)  LDD2203  [12]
 LDCM0427  Fragment51 HCT 116 C105(0.92)  LDD0744  [4]
 LDCM0569  Fragment7 Ramos C471(0.62)  LDD2186  [12]
 LDCM0571  Fragment9 Ramos C471(0.78)  LDD2188  [12]
 LDCM0022  KB02 HEK-293T C149(1.02); C105(1.06); C80(1.04)  LDD1492  [11]
 LDCM0023  KB03 HEK-293T C149(1.04); C105(0.96); C80(1.13)  LDD1497  [11]
 LDCM0024  KB05 SKMEL24 C105(2.17)  LDD3323  [13]

References

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Mass spectrometry data entry: PXD028270
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3 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
4 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
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Mass spectrometry data entry: PXD028853
6 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
7 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
8 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
9 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
10 Pharmacological Targeting of Vacuolar H(+)-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer. Cell Chem Biol. 2020 Nov 19;27(11):1359-1370.e8. doi: 10.1016/j.chembiol.2020.06.011. Epub 2020 Jul 9.
11 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
12 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
13 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840