Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name IA-alkyne  Probe Info 
Probe concentration 100 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
Isotope tag
Competitor Name BPK-21  Competitor Info 
Competitor Concentration 20 uM
In Vivo Experiment Model Model Type Cell lysate
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cell lysate (T cell)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 9 Protein Related to This Bioclass
Target ID Target Name Binding Sites Binding Ratio
 LDTP04358  Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) C96 20.0
 LDTP04120  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) C193 20.0
 LDTP13219  GTPase IMAP family member 2 (GIMAP2) C261 20.0
 LDTP03540  Heme oxygenase 2 (HMOX2) C282 20.0
 LDTP11127  ADP-dependent glucokinase (ADPGK) C40 15.7
 LDTP03000  General transcription and DNA repair factor IIH helicase subunit XPB (ERCC3) C342 15.1
 LDTP00697  Cytochrome b5 type B (CYB5B) C115 7.5
 LDTP00464  Glutathione S-transferase 3, mitochondrial (MGST3) C56 7.3
 LDTP12841  Very long chain fatty acid elongase 5 (ELOVL5) C61 7.1
Transporter and channel
Click to Show/Hide to Show 7 Protein Related to This Bioclass
Target ID Target Name Binding Sites Binding Ratio
 LDTP05292  Fatty acid-binding protein 5 (FABP5) C120, C127 20.0
 LDTP18053  Probable mitochondrial glutathione transporter SLC25A40 (SLC25A40) C142 20.0
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) C210, C227 20.0
 LDTP08344  Stimulator of interferon genes protein (STING1) C88, C91 13.7
 LDTP14235  Mitochondrial carrier homolog 2 (MTCH2) C160, C163 12.8
 LDTP10826  Protein cereblon (CRBN) C287 9.6
 LDTP12909  Mitochondrial carrier homolog 1 (MTCH1) C385 7.8
Immunoglobulin
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Sites Binding Ratio
 LDTP00671  Tapasin (TAPBP) C440 6.5
Other
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Sites Binding Ratio
 LDTP05257  Receptor expression-enhancing protein 5 (REEP5) C18 20.0
 LDTP12412  Reticulon-4 (RTN4) C1101 20.0

References

1 An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells. Cell. 2020 Aug 20;182(4):1009-1026.e29. doi: 10.1016/j.cell.2020.07.001. Epub 2020 Jul 29.