General Information of Experiment

Probe Name P11  Probe Info 
Probe concentration 1 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
SILAC
Competitor Name C45  Competitor Info 
Competitor Concentration 1 uM
In Vivo Experiment Model Model Type Cell lysate
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cell lysate (HEK-293T)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP17022  Secernin-3 (SCRN3) 1.9
 LDTP00697  Cytochrome b5 type B (CYB5B) 1.6
 LDTP05128  Glutathione S-transferase omega-1 (GSTO1) 1.1
Transporter and channel
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP13824  Voltage-dependent anion-selective channel protein 3 (VDAC3) 1.1
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 1.0
Other
Click to Show/Hide to Show 4 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03614  Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) 1.3
 LDTP06021  Cytoskeleton-associated protein 5 (CKAP5) 1.1
 LDTP07598  BRCA1-associated ATM activator 1 (BRAT1) 1.0
 LDTP05257  Receptor expression-enhancing protein 5 (REEP5) 1.0

References

1 Discovery of Potent and Selective Inhibitors against Protein-Derived Electrophilic Cofactors. J Am Chem Soc. 2022 Mar 30;144(12):5377-5388. doi: 10.1021/jacs.1c12748. Epub 2022 Mar 2.