General Information of Experiment

Probe Name AX-1  Probe Info 
Probe concentration 1 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
SILAC
Competitor Name 9im  Competitor Info 
Competitor Concentration 10 uM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Breast
Disease Model Breast adenocarcinoma [ICD-11:2C60]
Model Name Human breast adenocarcinoma cells (MDA-MB-231)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP15484  Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) 5.1
 LDTP02848  NADPH--cytochrome P450 reductase (POR) 3.4
 LDTP07504  Lysophospholipid acyltransferase 5 (LPCAT3) 3.2
Transporter and channel
Click to Show/Hide to Show 6 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) 4.6
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 4.3
 LDTP04426  B-cell receptor-associated protein 31 (BCAP31) 3.7
 LDTP18448  Transmembrane 9 superfamily member 3 (TM9SF3) 3.1
 LDTP03405  Calnexin (CANX) 2.5
 LDTP05394  Caveolin-1 (CAV1) 2.4

References

1 Cell- and Tissue-Based Proteome Profiling and Bioimaging with Probes Derived from a Potent AXL Kinase Inhibitor. Chem Asian J. 2018 Sep 17;13(18):2601-2605. doi: 10.1002/asia.201800605. Epub 2018 Aug 7.