Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C432 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP02175 | Epoxide hydrolase 1 (EPHX1) | 15.9 | ||||
| LDTP09874 | Endoplasmic reticulum protein SC65 (P3H4) | 9.9 | ||||
| LDTP01300 | Cartilage-associated protein (CRTAP) | 9.5 | ||||
| LDTP01419 | Retinal dehydrogenase 2 (ALDH1A2) | 8.9 | ||||
| LDTP05758 | S-methyl-5'-thioadenosine phosphorylase (MTAP) | 8.6 | ||||
| LDTP04318 | Glycogen synthase kinase-3 alpha (GSK3A) | 8.2 | ||||
| LDTP02254 | ATP-dependent translocase ABCB1 (ABCB1) | 8.1 | ||||
| LDTP01687 | Apoptosis-inducing factor 1, mitochondrial (AIFM1) | 7.0 | ||||
| LDTP15484 | Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) | 6.9 | ||||
| LDTP03560 | Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) | 6.5 | ||||
| LDTP04004 | Lysosomal Pro-X carboxypeptidase (PRCP) | 6.1 | ||||
| LDTP13751 | Exonuclease 1 (EXO1) | 5.8 | ||||
| LDTP08979 | Prostaglandin reductase 2 (PTGR2) | 5.7 | ||||
| LDTP15422 | Prostaglandin reductase 3 (PTGR3) | 5.6 | ||||
| LDTP02149 | Cyclin-dependent kinase 1 (CDK1) | 5.5 | ||||
| LDTP03299 | Cyclin-dependent kinase 2 (CDK2) | 5.5 | ||||
| LDTP13282 | Prenylcysteine oxidase 1 (PCYOX1) | 5.1 | ||||
| LDTP00589 | Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) | 5.0 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP07462 | MFS-type transporter SLC18B1 (SLC18B1) | 21.1 | ||||
| LDTP10913 | Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) | 11.6 | ||||
| LDTP16069 | Peroxisomal membrane protein 2 (PXMP2) | 8.9 | ||||
| LDTP14952 | Mpv17-like protein 2 (MPV17L2) | 8.6 | ||||
| LDTP00865 | Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) | 7.7 | ||||
| LDTP10958 | Sigma non-opioid intracellular receptor 1 (SIGMAR1) | 6.2 | ||||
| LDTP17641 | Solute carrier family 35 member F2 (SLC35F2) | 6.1 | ||||
| LDTP03952 | Reduced folate transporter (SLC19A1) | 5.7 | ||||
| LDTP09547 | Scavenger receptor class B member 1 (SCARB1) | 5.4 | ||||
| LDTP01059 | Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) | 5.1 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP01075 | Protein CutA (CUTA) | 32.2 | ||||
| LDTP15623 | Neuferricin (CYB5D2) | 15.6 | ||||
| LDTP03678 | ER lumen protein-retaining receptor 2 (KDELR2) | 6.4 | ||||
| LDTP14486 | Clustered mitochondria protein homolog (CLUH) | 5.0 | ||||