Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C274 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP03849 | Electron transfer flavoprotein subunit beta (ETFB) | 23.3 | ||||
| LDTP10182 | TLC domain-containing protein 1 (TLCD1) | 14.0 | ||||
| LDTP02150 | ATP synthase subunit beta, mitochondrial (ATP5F1B) | 11.6 | ||||
| LDTP01687 | Apoptosis-inducing factor 1, mitochondrial (AIFM1) | 11.5 | ||||
| LDTP03139 | Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) | 8.4 | ||||
| LDTP00575 | Glutathione S-transferase A4 (GSTA4) | 7.9 | ||||
| LDTP04051 | Nicotinamide phosphoribosyltransferase (NAMPT) | 6.8 | ||||
| LDTP15484 | Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) | 6.4 | ||||
| LDTP09088 | Phospholipase A2 group XV (PLA2G15) | 5.9 | ||||
| LDTP03787 | Choline kinase alpha (CHKA) | 5.7 | ||||
| LDTP05758 | S-methyl-5'-thioadenosine phosphorylase (MTAP) | 5.4 | ||||
| LDTP06333 | Serum paraoxonase/arylesterase 2 (PON2) | 5.4 | ||||
| LDTP04712 | Puromycin-sensitive aminopeptidase (NPEPPS) | 5.1 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP16069 | Peroxisomal membrane protein 2 (PXMP2) | 56.5 | ||||
| LDTP17362 | Magnesium transporter NIPA3 (NIPAL1) | 6.8 | ||||
| LDTP00865 | Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) | 6.6 | ||||
| LDTP10913 | Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) | 6.2 | ||||
| LDTP01059 | Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) | 6.1 | ||||
| LDTP07885 | Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) | 5.7 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP13630 | Neudesin (NENF) | 10.8 | ||||
| LDTP10381 | Peroxisomal membrane protein 11C (PEX11G) | 5.9 | ||||
| LDTP15623 | Neuferricin (CYB5D2) | 5.5 | ||||
| LDTP01196 | Adapter SH3BGRL (SH3BGRL) | 5.2 | ||||
| LDTP14486 | Clustered mitochondria protein homolog (CLUH) | 5.0 | ||||