General Information of Experiment

Probe Name C142  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 13 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP12628  Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) 26.7
 LDTP04004  Lysosomal Pro-X carboxypeptidase (PRCP) 13.8
 LDTP05724  Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) 10.8
 LDTP15422  Prostaglandin reductase 3 (PTGR3) 10.3
 LDTP02175  Epoxide hydrolase 1 (EPHX1) 8.5
 LDTP01687  Apoptosis-inducing factor 1, mitochondrial (AIFM1) 7.7
 LDTP04712  Puromycin-sensitive aminopeptidase (NPEPPS) 6.3
 LDTP05862  NAD(P) transhydrogenase, mitochondrial (NNT) 6.2
 LDTP03912  Trifunctional enzyme subunit alpha, mitochondrial (HADHA) 5.5
 LDTP03842  Squalene synthase (FDFT1) 5.4
 LDTP12013  dCTP pyrophosphatase 1 (DCTPP1) 5.2
 LDTP13751  Exonuclease 1 (EXO1) 5.0
 LDTP16032  Retinoid-inducible serine carboxypeptidase (SCPEP1) 5.0
Transporter and channel
Click to Show/Hide to Show 7 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP07667  Transmembrane protein 205 (TMEM205) 22.5
 LDTP17362  Magnesium transporter NIPA3 (NIPAL1) 12.0
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 10.6
 LDTP17641  Solute carrier family 35 member F2 (SLC35F2) 8.9
 LDTP16069  Peroxisomal membrane protein 2 (PXMP2) 8.7
 LDTP09968  V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) 7.9
 LDTP00865  Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) 5.8
Other
Click to Show/Hide to Show 4 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP04094  Large proline-rich protein BAG6 (BAG6) 8.3
 LDTP15623  Neuferricin (CYB5D2) 7.5
 LDTP00105  Protein unc-119 homolog B (UNC119B) 6.3
 LDTP15634  Ubiquinol-cytochrome c reductase complex assembly factor 5 (UQCC5) 5.6

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587