Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C045 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP08476 | 5'-3' exonuclease PLD3 (PLD3) | 18.8 | ||||
| LDTP02799 | N-acetylglucosamine-6-sulfatase (GNS) | 17.5 | ||||
| LDTP13620 | Lysosomal thioesterase PPT2 (PPT2) | 15.9 | ||||
| LDTP16032 | Retinoid-inducible serine carboxypeptidase (SCPEP1) | 15.6 | ||||
| LDTP04008 | Endothelin-converting enzyme 1 (ECE1) | 13.6 | ||||
| LDTP13358 | Leucyl-cystinyl aminopeptidase (LNPEP) | 12.7 | ||||
| LDTP00316 | Ribonuclease T2 (RNASET2) | 12.7 | ||||
| LDTP01241 | Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) | 12.0 | ||||
| LDTP06375 | Delta(24)-sterol reductase (DHCR24) | 11.6 | ||||
| LDTP00428 | Tripeptidyl-peptidase 1 (TPP1) | 11.2 | ||||
| LDTP02006 | Tissue alpha-L-fucosidase (FUCA1) | 11.0 | ||||
| LDTP02141 | Alpha-galactosidase A (GLA) | 10.2 | ||||
| LDTP15988 | Probable serine carboxypeptidase CPVL (CPVL) | 10.2 | ||||
| LDTP02169 | Beta-hexosaminidase subunit alpha (HEXA) | 9.6 | ||||
| LDTP09256 | Putative phospholipase B-like 2 (PLBD2) | 9.4 | ||||
| LDTP02539 | Lysosomal acid phosphatase (ACP2) | 9.2 | ||||
| LDTP04572 | Dipeptidyl peptidase 1 (CTSC) | 9.1 | ||||
| LDTP04388 | Palmitoyl-protein thioesterase 1 (PPT1) | 8.9 | ||||
| LDTP11215 | Plasma alpha-L-fucosidase (FUCA2) | 8.5 | ||||
| LDTP04634 | Alpha-N-acetylglucosaminidase (NAGLU) | 8.5 | ||||
| LDTP00338 | Lysosomal alpha-mannosidase (MAN2B1) | 7.5 | ||||
| LDTP09088 | Phospholipase A2 group XV (PLA2G15) | 6.5 | ||||
| LDTP02837 | Beta-galactosidase (GLB1) | 6.4 | ||||
| LDTP01372 | Carboxypeptidase D (CPD) | 6.2 | ||||
| LDTP12020 | Histone-lysine N-methyltransferase SMYD3 (SMYD3) | 6.0 | ||||
| LDTP09886 | Gamma-glutamyl hydrolase (GGH) | 5.9 | ||||
| LDTP05905 | Acid ceramidase (ASAH1) | 5.8 | ||||
| LDTP02216 | Beta-hexosaminidase subunit beta (HEXB) | 5.6 | ||||
| LDTP02505 | Lysosomal protective protein (CTSA) | 5.5 | ||||
| LDTP04004 | Lysosomal Pro-X carboxypeptidase (PRCP) | 5.3 | ||||
| LDTP02896 | Sphingomyelin phosphodiesterase (SMPD1) | 5.2 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP02215 | Prosaposin (PSAP) | 9.4 | ||||
| LDTP06034 | Lysosome membrane protein 2 (SCARB2) | 8.5 | ||||
| LDTP04940 | NPC intracellular cholesterol transporter 2 (NPC2) | 7.9 | ||||
| LDTP02586 | Cation-independent mannose-6-phosphate receptor (IGF2R) | 7.1 | ||||
| LDTP18153 | Major facilitator superfamily domain-containing protein 3 (MFSD3) | 7.0 | ||||
| LDTP02562 | Lysosome-associated membrane glycoprotein 1 (LAMP1) | 5.9 | ||||
| LDTP12451 | Integral membrane protein 2C (ITM2C) | 5.8 | ||||
| LDTP10885 | Sortilin (SORT1) | 5.6 | ||||
| LDTP10958 | Sigma non-opioid intracellular receptor 1 (SIGMAR1) | 5.1 | ||||
| LDTP03380 | Stomatin (STOM) | 5.0 | ||||
| LDTP01969 | Transferrin receptor protein 1 (TFRC) | 5.0 | ||||
| LDTP06499 | V-type proton ATPase subunit S1 (ATP6AP1) | 4.9 | ||||
Immunoglobulin
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP09907 | Neogenin (NEO1) | 8.7 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP02927 | Ganglioside GM2 activator (GM2A) | 15.0 | ||||
| LDTP05558 | Galectin-3-binding protein (LGALS3BP) | 9.4 | ||||
| LDTP00779 | Trans-Golgi network integral membrane protein 2 (TGOLN2) | 9.3 | ||||
| LDTP19021 | EF-hand calcium-binding domain-containing protein 14 (EFCAB14) | 8.8 | ||||
| LDTP13606 | Mammalian ependymin-related protein 1 (EPDR1) | 8.1 | ||||
| LDTP14458 | Tetraspanin-6 (TSPAN6) | 7.6 | ||||
| LDTP08130 | Rab9 effector protein with kelch motifs (RABEPK) | 6.7 | ||||
| LDTP08689 | Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) | 6.3 | ||||
| LDTP07031 | Collectin-12 (COLEC12) | 6.3 | ||||
| LDTP05960 | Trophoblast glycoprotein (TPBG) | 6.3 | ||||
| LDTP07934 | Synaptic vesicle glycoprotein 2A (SV2A) | 5.5 | ||||
| LDTP09787 | Nicastrin (NCSTN) | 5.2 | ||||