General Information of Experiment

Probe Name Kambe_31  Probe Info 
Probe concentration 10 uM
Criteria Quantification: Probe vs (Probe+Competitor)
Quantitative Method
SILAC
Competitor Name kambe_cp64  Competitor Info 
Competitor Concentration 20 uM
In Vivo Experiment Model Model Type Living cell
Derived Tissue Prostate
Disease Model Prostate carcinoma [ICD-11:2C82]
Model Name Human prostate carcinoma cells (PC-3)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 14 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP07003  Presequence protease, mitochondrial (PITRM1) 5.3
 LDTP05724  Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) 3.3
 LDTP06227  Prostaglandin reductase 1 (PTGR1) 3.2
 LDTP08979  Prostaglandin reductase 2 (PTGR2) 3.0
 LDTP16032  Retinoid-inducible serine carboxypeptidase (SCPEP1) 2.7
 LDTP04004  Lysosomal Pro-X carboxypeptidase (PRCP) 2.6
 LDTP02198  Cathepsin D (CTSD) 2.3
 LDTP03816  Oxidized purine nucleoside triphosphate hydrolase (NUDT1) 2.3
 LDTP03730  Sepiapterin reductase (SPR) 2.3
 LDTP03400  Deoxycytidine kinase (DCK) 2.2
 LDTP04051  Nicotinamide phosphoribosyltransferase (NAMPT) 2.2
 LDTP03642  Cytidine deaminase (CDA) 2.1
 LDTP02522  60 kDa heat shock protein, mitochondrial (HSPD1) 2.0
 LDTP03515  Thioredoxin-dependent peroxide reductase, mitochondrial (PRDX3) 2.0
Transporter and channel
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP04501  Importin subunit alpha-1 (KPNA2) 2.0
Other
Click to Show/Hide to Show 4 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP01075  Protein CutA (CUTA) 3.3
 LDTP06141  Keratin, type II cuticular Hb1 (KRT81) 2.4
 LDTP00868  Keratin, type II cuticular Hb6 (KRT86) 2.4
 LDTP13630  Neudesin (NENF) 2.3

References

1 Mapping the protein interaction landscape for fully functionalized small-molecule probes in human cells. J Am Chem Soc. 2014 Jul 30;136(30):10777-82. doi: 10.1021/ja505517t. Epub 2014 Jul 21.