Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C115 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP02799 | N-acetylglucosamine-6-sulfatase (GNS) | 18.4 | ||||
| LDTP00428 | Tripeptidyl-peptidase 1 (TPP1) | 18.4 | ||||
| LDTP01241 | Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) | 17.4 | ||||
| LDTP16032 | Retinoid-inducible serine carboxypeptidase (SCPEP1) | 14.6 | ||||
| LDTP13358 | Leucyl-cystinyl aminopeptidase (LNPEP) | 12.7 | ||||
| LDTP00316 | Ribonuclease T2 (RNASET2) | 12.7 | ||||
| LDTP04008 | Endothelin-converting enzyme 1 (ECE1) | 12.6 | ||||
| LDTP13620 | Lysosomal thioesterase PPT2 (PPT2) | 12.6 | ||||
| LDTP02006 | Tissue alpha-L-fucosidase (FUCA1) | 11.5 | ||||
| LDTP13131 | 7-dehydrocholesterol reductase (DHCR7) | 10.8 | ||||
| LDTP04388 | Palmitoyl-protein thioesterase 1 (PPT1) | 8.9 | ||||
| LDTP02896 | Sphingomyelin phosphodiesterase (SMPD1) | 8.4 | ||||
| LDTP02141 | Alpha-galactosidase A (GLA) | 7.8 | ||||
| LDTP15988 | Probable serine carboxypeptidase CPVL (CPVL) | 7.7 | ||||
| LDTP02486 | Lysosomal alpha-glucosidase (GAA) | 7.6 | ||||
| LDTP00907 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) | 7.2 | ||||
| LDTP02169 | Beta-hexosaminidase subunit alpha (HEXA) | 7.2 | ||||
| LDTP01372 | Carboxypeptidase D (CPD) | 7.1 | ||||
| LDTP04572 | Dipeptidyl peptidase 1 (CTSC) | 7.1 | ||||
| LDTP14305 | Bis(5'-adenosyl)-triphosphatase ENPP4 (ENPP4) | 6.6 | ||||
| LDTP11215 | Plasma alpha-L-fucosidase (FUCA2) | 6.6 | ||||
| LDTP02539 | Lysosomal acid phosphatase (ACP2) | 6.2 | ||||
| LDTP09256 | Putative phospholipase B-like 2 (PLBD2) | 6.2 | ||||
| LDTP00338 | Lysosomal alpha-mannosidase (MAN2B1) | 5.9 | ||||
| LDTP06375 | Delta(24)-sterol reductase (DHCR24) | 5.8 | ||||
| LDTP04634 | Alpha-N-acetylglucosaminidase (NAGLU) | 5.7 | ||||
| LDTP08476 | 5'-3' exonuclease PLD3 (PLD3) | 5.4 | ||||
| LDTP02505 | Lysosomal protective protein (CTSA) | 5.3 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP11615 | Protein tweety homolog 3 (TTYH3) | 13.1 | ||||
| LDTP02215 | Prosaposin (PSAP) | 12.1 | ||||
| LDTP13833 | Integral membrane protein 2B (ITM2B) | 11.8 | ||||
| LDTP01829 | Low-density lipoprotein receptor (LDLR) | 11.1 | ||||
| LDTP01969 | Transferrin receptor protein 1 (TFRC) | 10.0 | ||||
| LDTP02071 | Amyloid-beta precursor protein (APP) | 9.5 | ||||
| LDTP02586 | Cation-independent mannose-6-phosphate receptor (IGF2R) | 8.5 | ||||
| LDTP06034 | Lysosome membrane protein 2 (SCARB2) | 8.2 | ||||
| LDTP08016 | Proton-coupled amino acid transporter 1 (SLC36A1) | 7.6 | ||||
| LDTP17641 | Solute carrier family 35 member F2 (SLC35F2) | 7.3 | ||||
| LDTP05538 | Prolow-density lipoprotein receptor-related protein 1 (LRP1) | 7.2 | ||||
| LDTP12451 | Integral membrane protein 2C (ITM2C) | 7.0 | ||||
| LDTP10885 | Sortilin (SORT1) | 5.9 | ||||
| LDTP02655 | Lysosome-associated membrane glycoprotein 2 (LAMP2) | 5.7 | ||||
| LDTP09547 | Scavenger receptor class B member 1 (SCARB1) | 5.5 | ||||
| LDTP03380 | Stomatin (STOM) | 5.5 | ||||
| LDTP04940 | NPC intracellular cholesterol transporter 2 (NPC2) | 5.4 | ||||
| LDTP16813 | Tetraspanin-3 (TSPAN3) | 5.2 | ||||
| LDTP02562 | Lysosome-associated membrane glycoprotein 1 (LAMP1) | 5.0 | ||||
Immunoglobulin
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP09907 | Neogenin (NEO1) | 16.9 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP07703 | Seizure 6-like protein 2 (SEZ6L2) | 25.1 | ||||
| LDTP13114 | C-type mannose receptor 2 (MRC2) | 10.1 | ||||
| LDTP13606 | Mammalian ependymin-related protein 1 (EPDR1) | 9.4 | ||||
| LDTP00779 | Trans-Golgi network integral membrane protein 2 (TGOLN2) | 8.5 | ||||
| LDTP07031 | Collectin-12 (COLEC12) | 8.4 | ||||
| LDTP05491 | Amyloid beta precursor like protein 2 (APLP2) | 8.3 | ||||
| LDTP05558 | Galectin-3-binding protein (LGALS3BP) | 7.9 | ||||
| LDTP08689 | Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) | 6.8 | ||||
| LDTP02927 | Ganglioside GM2 activator (GM2A) | 6.3 | ||||
| LDTP05960 | Trophoblast glycoprotein (TPBG) | 5.1 | ||||
| LDTP19780 | Keratinocyte-associated transmembrane protein 2 (KCT2) | 5.1 | ||||
| LDTP06154 | Desmocollin-3 (DSC3) | 5.0 | ||||
| LDTP14458 | Tetraspanin-6 (TSPAN6) | 5.0 | ||||