Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C182 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP13620 | Lysosomal thioesterase PPT2 (PPT2) | 11.2 | ||||
| LDTP06200 | Delta(14)-sterol reductase LBR (LBR) | 9.4 | ||||
| LDTP03842 | Squalene synthase (FDFT1) | 7.9 | ||||
| LDTP13358 | Leucyl-cystinyl aminopeptidase (LNPEP) | 7.1 | ||||
| LDTP04008 | Endothelin-converting enzyme 1 (ECE1) | 6.6 | ||||
| LDTP01982 | NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) | 6.5 | ||||
| LDTP04285 | Proteasome subunit beta type-2 (PSMB2) | 6.4 | ||||
| LDTP16032 | Retinoid-inducible serine carboxypeptidase (SCPEP1) | 6.3 | ||||
| LDTP09043 | Lysine-specific histone demethylase 2 (KDM1B) | 6.2 | ||||
| LDTP03417 | Proteasome subunit beta type-4 (PSMB4) | 6.2 | ||||
| LDTP03608 | RAC-beta serine/threonine-protein kinase (AKT2) | 5.7 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP01059 | Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) | 24.4 | ||||
| LDTP10913 | Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) | 11.6 | ||||
| LDTP07885 | Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) | 7.7 | ||||
| LDTP17641 | Solute carrier family 35 member F2 (SLC35F2) | 7.7 | ||||
| LDTP06945 | Sigma intracellular receptor 2 (TMEM97) | 6.8 | ||||
| LDTP11615 | Protein tweety homolog 3 (TTYH3) | 6.4 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP13755 | Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) | 9.6 | ||||
| LDTP15714 | Mdm2-binding protein (MTBP) | 7.8 | ||||
| LDTP08689 | Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) | 6.7 | ||||
| LDTP14486 | Clustered mitochondria protein homolog (CLUH) | 6.6 | ||||
| LDTP02656 | Ribonuclease inhibitor (RNH1) | 5.9 | ||||
| LDTP09920 | Golgi apparatus protein 1 (GLG1) | 5.2 | ||||
| LDTP13114 | C-type mannose receptor 2 (MRC2) | 5.0 | ||||