Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C385 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP12013 | dCTP pyrophosphatase 1 (DCTPP1) | 44.9 | ||||
| LDTP09043 | Lysine-specific histone demethylase 2 (KDM1B) | 22.8 | ||||
| LDTP13282 | Prenylcysteine oxidase 1 (PCYOX1) | 20.7 | ||||
| LDTP05758 | S-methyl-5'-thioadenosine phosphorylase (MTAP) | 15.8 | ||||
| LDTP15422 | Prostaglandin reductase 3 (PTGR3) | 13.0 | ||||
| LDTP00907 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) | 9.9 | ||||
| LDTP04285 | Proteasome subunit beta type-2 (PSMB2) | 9.7 | ||||
| LDTP16032 | Retinoid-inducible serine carboxypeptidase (SCPEP1) | 7.8 | ||||
| LDTP04542 | Thimet oligopeptidase (THOP1) | 7.8 | ||||
| LDTP04004 | Lysosomal Pro-X carboxypeptidase (PRCP) | 7.0 | ||||
| LDTP11273 | N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) | 6.4 | ||||
| LDTP04388 | Palmitoyl-protein thioesterase 1 (PPT1) | 5.4 | ||||
| LDTP12020 | Histone-lysine N-methyltransferase SMYD3 (SMYD3) | 5.3 | ||||
| LDTP04211 | Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) | 5.2 | ||||
| LDTP13358 | Leucyl-cystinyl aminopeptidase (LNPEP) | 5.2 | ||||
| LDTP02175 | Epoxide hydrolase 1 (EPHX1) | 5.0 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP03132 | Voltage-dependent anion-selective channel protein 1 (VDAC1) | 16.0 | ||||
| LDTP04502 | Importin subunit alpha-5 (KPNA1) | 9.2 | ||||
| LDTP01059 | Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) | 7.7 | ||||
| LDTP04071 | Voltage-dependent anion-selective channel protein 2 (VDAC2) | 7.5 | ||||
| LDTP10913 | Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) | 6.7 | ||||
| LDTP06034 | Lysosome membrane protein 2 (SCARB2) | 6.0 | ||||
| LDTP00970 | Gasdermin-E (GSDME) | 5.8 | ||||
| LDTP06945 | Sigma intracellular receptor 2 (TMEM97) | 5.7 | ||||
| LDTP07236 | Protein GPR107 (GPR107) | 5.6 | ||||
| LDTP00865 | Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) | 5.5 | ||||
Immunoglobulin
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP03538 | HLA class I histocompatibility antigen, alpha chain F (HLA-F) | 5.1 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP14486 | Clustered mitochondria protein homolog (CLUH) | 13.5 | ||||
| LDTP05160 | Nucleobindin-2 (NUCB2) | 6.9 | ||||
| LDTP13755 | Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) | 6.5 | ||||
| LDTP14263 | TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (TAF6L) | 5.7 | ||||
| LDTP07839 | Capping protein-inhibiting regulator of actin dynamics (CRACD) | 5.6 | ||||
| LDTP15623 | Neuferricin (CYB5D2) | 4.9 | ||||