Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C042  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 7 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP12013  dCTP pyrophosphatase 1 (DCTPP1) 9.8
 LDTP04285  Proteasome subunit beta type-2 (PSMB2) 7.3
 LDTP02359  Heme oxygenase 1 (HMOX1) 6.8
 LDTP06645  Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) 6.0
 LDTP02175  Epoxide hydrolase 1 (EPHX1) 5.5
 LDTP04004  Lysosomal Pro-X carboxypeptidase (PRCP) 5.3
 LDTP16032  Retinoid-inducible serine carboxypeptidase (SCPEP1) 4.9
Transporter and channel
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP09547  Scavenger receptor class B member 1 (SCARB1) 4.9
Other
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP12565  Mitochondrial import receptor subunit TOM22 homolog (TOMM22) 6.7
 LDTP00105  Protein unc-119 homolog B (UNC119B) 5.1

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587