Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C359  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 7 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP15422  Prostaglandin reductase 3 (PTGR3) 26.4
 LDTP12013  dCTP pyrophosphatase 1 (DCTPP1) 19.0
 LDTP16032  Retinoid-inducible serine carboxypeptidase (SCPEP1) 8.1
 LDTP04051  Nicotinamide phosphoribosyltransferase (NAMPT) 7.1
 LDTP13358  Leucyl-cystinyl aminopeptidase (LNPEP) 6.2
 LDTP04004  Lysosomal Pro-X carboxypeptidase (PRCP) 5.8
 LDTP16007  Lipid droplet-associated hydrolase (LDAH) 5.5
Transporter and channel
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP00865  Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) 5.7
Immunoglobulin
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP01913  HLA class I histocompatibility antigen, B alpha chain (HLA-B) 6.0
Other
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP00105  Protein unc-119 homolog B (UNC119B) 8.9
 LDTP15623  Neuferricin (CYB5D2) 8.6
 LDTP09297  Large ribosomal subunit protein mL64 (GADD45GIP1) 6.2

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587