Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C336  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 7 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP09256  Putative phospholipase B-like 2 (PLBD2) 9.6
 LDTP16032  Retinoid-inducible serine carboxypeptidase (SCPEP1) 7.9
 LDTP02539  Lysosomal acid phosphatase (ACP2) 6.3
 LDTP00316  Ribonuclease T2 (RNASET2) 6.3
 LDTP13358  Leucyl-cystinyl aminopeptidase (LNPEP) 6.1
 LDTP02141  Alpha-galactosidase A (GLA) 5.7
 LDTP01241  Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) 5.5
Transporter and channel
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP02071  Amyloid-beta precursor protein (APP) 7.7
 LDTP17641  Solute carrier family 35 member F2 (SLC35F2) 6.3
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 6.2
Other
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP07703  Seizure 6-like protein 2 (SEZ6L2) 9.3
 LDTP05558  Galectin-3-binding protein (LGALS3BP) 5.7

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587