Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C164 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP09256 | Putative phospholipase B-like 2 (PLBD2) | 16.3 | ||||
| LDTP01328 | CAAX prenyl protease 1 homolog (ZMPSTE24) | 15.3 | ||||
| LDTP13620 | Lysosomal thioesterase PPT2 (PPT2) | 13.5 | ||||
| LDTP00907 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) | 13.0 | ||||
| LDTP13358 | Leucyl-cystinyl aminopeptidase (LNPEP) | 12.0 | ||||
| LDTP16032 | Retinoid-inducible serine carboxypeptidase (SCPEP1) | 11.2 | ||||
| LDTP00316 | Ribonuclease T2 (RNASET2) | 10.7 | ||||
| LDTP02141 | Alpha-galactosidase A (GLA) | 10.2 | ||||
| LDTP00428 | Tripeptidyl-peptidase 1 (TPP1) | 9.6 | ||||
| LDTP10888 | Legumain (LGMN) | 8.7 | ||||
| LDTP02505 | Lysosomal protective protein (CTSA) | 8.5 | ||||
| LDTP01241 | Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) | 7.2 | ||||
| LDTP03787 | Choline kinase alpha (CHKA) | 7.2 | ||||
| LDTP06375 | Delta(24)-sterol reductase (DHCR24) | 7.1 | ||||
| LDTP06325 | 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) | 6.7 | ||||
| LDTP02799 | N-acetylglucosamine-6-sulfatase (GNS) | 6.4 | ||||
| LDTP11215 | Plasma alpha-L-fucosidase (FUCA2) | 6.4 | ||||
| LDTP04008 | Endothelin-converting enzyme 1 (ECE1) | 6.2 | ||||
| LDTP08476 | 5'-3' exonuclease PLD3 (PLD3) | 6.1 | ||||
| LDTP02169 | Beta-hexosaminidase subunit alpha (HEXA) | 6.1 | ||||
| LDTP09395 | Signal peptide peptidase-like 2A (SPPL2A) | 6.0 | ||||
| LDTP01372 | Carboxypeptidase D (CPD) | 5.9 | ||||
| LDTP08265 | N-alpha-acetyltransferase 40 (NAA40) | 5.9 | ||||
| LDTP03692 | Bifunctional epoxide hydrolase 2 (EPHX2) | 5.9 | ||||
| LDTP02539 | Lysosomal acid phosphatase (ACP2) | 5.9 | ||||
| LDTP02486 | Lysosomal alpha-glucosidase (GAA) | 5.6 | ||||
| LDTP04388 | Palmitoyl-protein thioesterase 1 (PPT1) | 5.3 | ||||
| LDTP06648 | Lanosterol 14-alpha demethylase (CYP51A1) | 5.1 | ||||
| LDTP03769 | Sterol O-acyltransferase 1 (SOAT1) | 5.0 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP02071 | Amyloid-beta precursor protein (APP) | 13.8 | ||||
| LDTP10913 | Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) | 10.4 | ||||
| LDTP02215 | Prosaposin (PSAP) | 10.2 | ||||
| LDTP01059 | Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) | 9.8 | ||||
| LDTP16813 | Tetraspanin-3 (TSPAN3) | 9.0 | ||||
| LDTP10885 | Sortilin (SORT1) | 7.0 | ||||
| LDTP01969 | Transferrin receptor protein 1 (TFRC) | 6.8 | ||||
| LDTP02586 | Cation-independent mannose-6-phosphate receptor (IGF2R) | 6.2 | ||||
| LDTP02655 | Lysosome-associated membrane glycoprotein 2 (LAMP2) | 5.6 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP05558 | Galectin-3-binding protein (LGALS3BP) | 6.2 | ||||
| LDTP02927 | Ganglioside GM2 activator (GM2A) | 5.7 | ||||
| LDTP00105 | Protein unc-119 homolog B (UNC119B) | 5.5 | ||||
| LDTP07031 | Collectin-12 (COLEC12) | 4.9 | ||||