Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | FFF probe12 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:20uM; negative probe:20uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
SILAC
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP08476 | 5'-3' exonuclease PLD3 (PLD3) | 20.0 | ||||
| LDTP02141 | Alpha-galactosidase A (GLA) | 20.0 | ||||
| LDTP04634 | Alpha-N-acetylglucosaminidase (NAGLU) | 20.0 | ||||
| LDTP01687 | Apoptosis-inducing factor 1, mitochondrial (AIFM1) | 20.0 | ||||
| LDTP02837 | Beta-galactosidase (GLB1) | 20.0 | ||||
| LDTP02169 | Beta-hexosaminidase subunit alpha (HEXA) | 20.0 | ||||
| LDTP02216 | Beta-hexosaminidase subunit beta (HEXB) | 20.0 | ||||
| LDTP01241 | Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) | 20.0 | ||||
| LDTP05992 | Bleomycin hydrolase (BLMH) | 20.0 | ||||
| LDTP02223 | Cathepsin B (CTSB) | 20.0 | ||||
| LDTP02198 | Cathepsin D (CTSD) | 20.0 | ||||
| LDTP06375 | Delta(24)-sterol reductase (DHCR24) | 20.0 | ||||
| LDTP04572 | Dipeptidyl peptidase 1 (CTSC) | 20.0 | ||||
| LDTP04008 | Endothelin-converting enzyme 1 (ECE1) | 20.0 | ||||
| LDTP09886 | Gamma-glutamyl hydrolase (GGH) | 20.0 | ||||
| LDTP10888 | Legumain (LGMN) | 20.0 | ||||
| LDTP13358 | Leucyl-cystinyl aminopeptidase (LNPEP) | 20.0 | ||||
| LDTP02005 | Lysosomal acid glucosylceramidase (GBA1) | 20.0 | ||||
| LDTP03858 | Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA) | 20.0 | ||||
| LDTP02539 | Lysosomal acid phosphatase (ACP2) | 20.0 | ||||
| LDTP02486 | Lysosomal alpha-glucosidase (GAA) | 20.0 | ||||
| LDTP04004 | Lysosomal Pro-X carboxypeptidase (PRCP) | 20.0 | ||||
| LDTP02799 | N-acetylglucosamine-6-sulfatase (GNS) | 20.0 | ||||
| LDTP04388 | Palmitoyl-protein thioesterase 1 (PPT1) | 20.0 | ||||
| LDTP05372 | Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) | 20.0 | ||||
| LDTP11215 | Plasma alpha-L-fucosidase (FUCA2) | 20.0 | ||||
| LDTP13282 | Prenylcysteine oxidase 1 (PCYOX1) | 20.0 | ||||
| LDTP15988 | Probable serine carboxypeptidase CPVL (CPVL) | 20.0 | ||||
| LDTP08979 | Prostaglandin reductase 2 (PTGR2) | 20.0 | ||||
| LDTP16032 | Retinoid-inducible serine carboxypeptidase (SCPEP1) | 20.0 | ||||
| LDTP02006 | Tissue alpha-L-fucosidase (FUCA1) | 20.0 | ||||
| LDTP00428 | Tripeptidyl-peptidase 1 (TPP1) | 20.0 | ||||
| LDTP03560 | Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) | 19.4 | ||||
| LDTP04211 | Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) | 18.9 | ||||
| LDTP04399 | Ras-related protein Rab-7a (RAB7A) | 7.9 | ||||
| LDTP04712 | Puromycin-sensitive aminopeptidase (NPEPPS) | 7.6 | ||||
| LDTP03419 | Proteasome subunit beta type-5 (PSMB5) | 6.0 | ||||
| LDTP02534 | Endoplasmic reticulum chaperone BiP (HSPA5) | 5.7 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP02071 | Amyloid-beta precursor protein (APP) | 20.0 | ||||
| LDTP02058 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (RPN2) | 20.0 | ||||
| LDTP03277 | ER lumen protein-retaining receptor 1 (KDELR1) | 20.0 | ||||
| LDTP01366 | Flotillin-1 (FLOT1) | 20.0 | ||||
| LDTP06034 | Lysosome membrane protein 2 (SCARB2) | 20.0 | ||||
| LDTP02655 | Lysosome-associated membrane glycoprotein 2 (LAMP2) | 20.0 | ||||
| LDTP00865 | Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) | 20.0 | ||||
| LDTP10913 | Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) | 20.0 | ||||
| LDTP01059 | Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) | 20.0 | ||||
| LDTP04940 | NPC intracellular cholesterol transporter 2 (NPC2) | 20.0 | ||||
| LDTP02215 | Prosaposin (PSAP) | 20.0 | ||||
| LDTP12042 | Proton-activated chloride channel (PACC1) | 20.0 | ||||
| LDTP17641 | Solute carrier family 35 member F2 (SLC35F2) | 20.0 | ||||
| LDTP00310 | Syntenin-1 (SDCBP) | 20.0 | ||||
| LDTP01969 | Transferrin receptor protein 1 (TFRC) | 20.0 | ||||
| LDTP03132 | Voltage-dependent anion-selective channel protein 1 (VDAC1) | 19.6 | ||||
| LDTP03402 | Calreticulin (CALR) | 15.8 | ||||
| LDTP03405 | Calnexin (CANX) | 8.9 | ||||
| LDTP04071 | Voltage-dependent anion-selective channel protein 2 (VDAC2) | 7.2 | ||||
| LDTP03870 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (DDOST) | 6.1 | ||||
| LDTP02057 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (RPN1) | 5.5 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP05491 | Amyloid beta precursor like protein 2 (APLP2) | 20.0 | ||||
| LDTP00887 | Calumenin (CALU) | 20.0 | ||||
| LDTP00281 | Golgi integral membrane protein 4 (GOLIM4) | 20.0 | ||||
| LDTP04684 | Nucleosome assembly protein 1-like 1 (NAP1L1) | 20.0 | ||||
| LDTP10965 | Nucleosome assembly protein 1-like 4 (NAP1L4) | 20.0 | ||||
| LDTP06352 | Reticulocalbin-1 (RCN1) | 20.0 | ||||
| LDTP06097 | Reticulocalbin-2 (RCN2) | 20.0 | ||||
| LDTP14458 | Tetraspanin-6 (TSPAN6) | 20.0 | ||||
| LDTP02734 | Endoplasmin (HSP90B1) | 10.1 | ||||
| LDTP02297 | Vimentin (VIM) | 5.5 | ||||