Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C351 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP06333 | Serum paraoxonase/arylesterase 2 (PON2) | 27.1 | ||||
| LDTP01769 | Dihydrofolate reductase (DHFR) | 25.3 | ||||
| LDTP01982 | NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) | 21.9 | ||||
| LDTP03331 | Proteasome subunit alpha type-2 (PSMA2) | 20.1 | ||||
| LDTP02175 | Epoxide hydrolase 1 (EPHX1) | 16.2 | ||||
| LDTP06375 | Delta(24)-sterol reductase (DHCR24) | 13.0 | ||||
| LDTP01039 | Protein-S-isoprenylcysteine O-methyltransferase (ICMT) | 12.8 | ||||
| LDTP09088 | Phospholipase A2 group XV (PLA2G15) | 12.4 | ||||
| LDTP02565 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) | 9.5 | ||||
| LDTP03842 | Squalene synthase (FDFT1) | 9.0 | ||||
| LDTP05396 | Histone-lysine N-methyltransferase 2A (KMT2A) | 8.6 | ||||
| LDTP12020 | Histone-lysine N-methyltransferase SMYD3 (SMYD3) | 8.5 | ||||
| LDTP06618 | ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) | 8.2 | ||||
| LDTP13112 | Phosphatidylinositol 4-kinase beta (PI4KB) | 7.9 | ||||
| LDTP12363 | Lysophosphatidic acid phosphatase type 6 (ACP6) | 7.8 | ||||
| LDTP10101 | Peptidyl-prolyl cis-trans isomerase FKBP10 (FKBP10) | 7.7 | ||||
| LDTP13282 | Prenylcysteine oxidase 1 (PCYOX1) | 7.0 | ||||
| LDTP09043 | Lysine-specific histone demethylase 2 (KDM1B) | 6.8 | ||||
| LDTP12868 | Endoplasmic reticulum aminopeptidase 1 (ERAP1) | 6.3 | ||||
| LDTP05029 | Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) | 6.2 | ||||
| LDTP04004 | Lysosomal Pro-X carboxypeptidase (PRCP) | 6.0 | ||||
| LDTP06200 | Delta(14)-sterol reductase LBR (LBR) | 5.9 | ||||
| LDTP03417 | Proteasome subunit beta type-4 (PSMB4) | 5.6 | ||||
| LDTP05758 | S-methyl-5'-thioadenosine phosphorylase (MTAP) | 5.4 | ||||
| LDTP11437 | Peroxisomal trans-2-enoyl-CoA reductase (PECR) | 5.1 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP10958 | Sigma non-opioid intracellular receptor 1 (SIGMAR1) | 11.9 | ||||
| LDTP07885 | Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) | 10.0 | ||||
| LDTP01804 | ATP synthase subunit a (MT-ATP6) | 7.7 | ||||
| LDTP08881 | Transmembrane protein 199 (TMEM199) | 5.9 | ||||
| LDTP09547 | Scavenger receptor class B member 1 (SCARB1) | 5.6 | ||||
| LDTP00865 | Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) | 5.4 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP03520 | Phosphatidylethanolamine-binding protein 1 (PEBP1) | 11.6 | ||||
| LDTP01075 | Protein CutA (CUTA) | 6.3 | ||||
| LDTP01652 | Centrosomal protein 43 (CEP43) | 6.2 | ||||
| LDTP06097 | Reticulocalbin-2 (RCN2) | 6.0 | ||||
| LDTP07476 | RAD50-interacting protein 1 (RINT1) | 6.0 | ||||
| LDTP16193 | Craniofacial development protein 1 (CFDP1) | 5.5 | ||||
| LDTP16192 | Mitochondrial fission process protein 1 (MTFP1) | 5.3 | ||||