Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C176 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP04004 | Lysosomal Pro-X carboxypeptidase (PRCP) | 17.4 | ||||
| LDTP11321 | Acetyl-CoA acetyltransferase, cytosolic (ACAT2) | 12.1 | ||||
| LDTP16007 | Lipid droplet-associated hydrolase (LDAH) | 9.2 | ||||
| LDTP02640 | X-ray repair cross-complementing protein 6 (XRCC6) | 7.9 | ||||
| LDTP03540 | Heme oxygenase 2 (HMOX2) | 6.9 | ||||
| LDTP06849 | Prolyl endopeptidase-like (PREPL) | 6.9 | ||||
| LDTP13751 | Exonuclease 1 (EXO1) | 6.8 | ||||
| LDTP03257 | Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) | 6.6 | ||||
| LDTP04712 | Puromycin-sensitive aminopeptidase (NPEPPS) | 6.1 | ||||
| LDTP12013 | dCTP pyrophosphatase 1 (DCTPP1) | 6.1 | ||||
| LDTP01982 | NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) | 6.1 | ||||
| LDTP12363 | Lysophosphatidic acid phosphatase type 6 (ACP6) | 6.0 | ||||
| LDTP04008 | Endothelin-converting enzyme 1 (ECE1) | 5.6 | ||||
| LDTP03560 | Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) | 5.4 | ||||
| LDTP15422 | Prostaglandin reductase 3 (PTGR3) | 5.4 | ||||
| LDTP10495 | Ubiquitin carboxyl-terminal hydrolase 47 (USP47) | 5.4 | ||||
| LDTP08017 | Endoplasmic reticulum metallopeptidase 1 (ERMP1) | 5.3 | ||||
| LDTP05724 | Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) | 5.1 | ||||
| LDTP00975 | Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (MAN1A2) | 5.1 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP14952 | Mpv17-like protein 2 (MPV17L2) | 10.1 | ||||
| LDTP17641 | Solute carrier family 35 member F2 (SLC35F2) | 9.2 | ||||
| LDTP01059 | Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) | 8.6 | ||||
| LDTP07885 | Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) | 8.4 | ||||
| LDTP10958 | Sigma non-opioid intracellular receptor 1 (SIGMAR1) | 8.3 | ||||
| LDTP07236 | Protein GPR107 (GPR107) | 7.6 | ||||
| LDTP10913 | Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) | 6.7 | ||||
| LDTP00865 | Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) | 6.2 | ||||
| LDTP06945 | Sigma intracellular receptor 2 (TMEM97) | 5.4 | ||||
| LDTP16813 | Tetraspanin-3 (TSPAN3) | 5.2 | ||||
| LDTP09261 | Major facilitator superfamily domain-containing protein 8 (MFSD8) | 5.1 | ||||
| LDTP03952 | Reduced folate transporter (SLC19A1) | 5.1 | ||||
| LDTP15948 | Transmembrane protein 126A (TMEM126A) | 5.0 | ||||
| LDTP06581 | Occludin (OCLN) | 5.0 | ||||
| LDTP11136 | Sugar transporter SWEET1 (SLC50A1) | 5.0 | ||||
| LDTP16069 | Peroxisomal membrane protein 2 (PXMP2) | 5.0 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP15623 | Neuferricin (CYB5D2) | 47.2 | ||||
| LDTP11533 | Oxysterol-binding protein-related protein 6 (OSBPL6) | 26.9 | ||||
| LDTP04094 | Large proline-rich protein BAG6 (BAG6) | 12.5 | ||||
| LDTP15067 | Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) | 6.5 | ||||
| LDTP14486 | Clustered mitochondria protein homolog (CLUH) | 5.7 | ||||
| LDTP15714 | Mdm2-binding protein (MTBP) | 5.7 | ||||
| LDTP09920 | Golgi apparatus protein 1 (GLG1) | 5.4 | ||||
| LDTP15420 | Mitochondrial import receptor subunit TOM5 homolog (TOMM5) | 5.2 | ||||
| LDTP05734 | Protein flightless-1 homolog (FLII) | 5.1 | ||||
| LDTP05960 | Trophoblast glycoprotein (TPBG) | 5.1 | ||||