General Information of Experiment

Probe Name AZ-9  Probe Info 
Probe concentration 10 uM
Criteria Qualitation: Labeling site identification
Quantitative Method
Isotope tag
In Vivo Experiment Model Model Type Living cell
Derived Tissue Breast
Disease Model Invasive breast carcinoma [ICD-11:2C60]
Model Name Human invasive breast carcinoma cells (MCF-7)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 19 Protein Related to This Bioclass
Target ID Target Name Binding Sites
 LDTP05069  Actin, alpha cardiac muscle 1 (ACTC1) D27
 LDTP05069  Actin, alpha cardiac muscle 1 (ACTC1) E243
 LDTP05073  Actin, alpha skeletal muscle (ACTA1) D27
 LDTP05073  Actin, alpha skeletal muscle (ACTA1) E243
 LDTP04999  Actin, aortic smooth muscle (ACTA2) D27
 LDTP04999  Actin, aortic smooth muscle (ACTA2) E243
 LDTP04876  Actin, cytoplasmic 1 (ACTB) D25
 LDTP04876  Actin, cytoplasmic 1 (ACTB) D311
 LDTP04876  Actin, cytoplasmic 1 (ACTB) E241
 LDTP05059  Actin, cytoplasmic 2 (ACTG1) D25
 LDTP05059  Actin, cytoplasmic 2 (ACTG1) D311
 LDTP05059  Actin, cytoplasmic 2 (ACTG1) E241
 LDTP05060  Actin, gamma-enteric smooth muscle (ACTG2) D26
 LDTP05060  Actin, gamma-enteric smooth muscle (ACTG2) E242
 LDTP02159  Alpha-enolase (ENO1) E219
 LDTP00697  Cytochrome b5 type B (CYB5B) E17
 LDTP02333  Glutathione S-transferase P (GSTP1) D60
 LDTP02713  Macrophage migration inhibitory factor (MIF) E86
 LDTP02502  Thioredoxin (TXN) E103
Transporter and channel
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Sites
 LDTP05165  Brain acid soluble protein 1 (BASP1) E34
 LDTP02262  Heat shock protein HSP 90-beta (HSP90AB1) E489
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) D239
Other
Click to Show/Hide to Show 47 Protein Related to This Bioclass
Target ID Target Name Binding Sites
 LDTP04595  Activated RNA polymerase II transcriptional coactivator p15 (SUB1) D119
 LDTP14951  Beta-actin-like protein 2 (ACTBL2) E242
 LDTP02441  Calmodulin-1 (CALM1) E8
 LDTP02442  Calmodulin-2 (CALM2) E8
 LDTP02443  Calmodulin-3 (CALM3) E8
 LDTP03244  Cofilin-1 (CFL1) D9
 LDTP03244  Cofilin-1 (CFL1) E142
 LDTP03244  Cofilin-1 (CFL1) S160
 LDTP02125  Keratin, type II cytoskeletal 8 (KRT8) E355
 LDTP02108  Large ribosomal subunit protein P2 (RPLP2) D53
 LDTP02108  Large ribosomal subunit protein P2 (RPLP2) D37
 LDTP13817  Nuclear migration protein nudC (NUDC) E52
 LDTP02412  Polyubiquitin-B (UBB) E24
 LDTP02412  Polyubiquitin-B (UBB) E18
 LDTP02413  Polyubiquitin-C (UBC) E24
 LDTP02413  Polyubiquitin-C (UBC) E18
 LDTP07634  POTE ankyrin domain family member E (POTEE) D725
 LDTP07634  POTE ankyrin domain family member E (POTEE) E941
 LDTP14342  POTE ankyrin domain family member F (POTEF) D725
 LDTP14342  POTE ankyrin domain family member F (POTEF) E941
 LDTP16895  POTE ankyrin domain family member I (POTEI) D725
 LDTP16896  POTE ankyrin domain family member J (POTEJ) D688
 LDTP01932  Prelamin-A/C (LMNA) E68
 LDTP01932  Prelamin-A/C (LMNA) E247
 LDTP03361  Protein S100-A4 (S100A4) E52
 LDTP02153  Protein S100-A6 (S100A6) E58
 LDTP02148  Prothymosin alpha (PTMA) D7
 LDTP02148  Prothymosin alpha (PTMA) D101
 LDTP02148  Prothymosin alpha (PTMA) E28
 LDTP11508  Putative beta-actin-like protein 3 (POTEKP) E241
 LDTP14956  Putative heat shock protein HSP 90-beta 2 (HSP90AB2P) E265
 LDTP04972  Small ribosomal subunit protein uS13 (RPS18) E61
 LDTP14778  Thymosin beta-10 (TMSB10) D3
 LDTP14778  Thymosin beta-10 (TMSB10) E36
 LDTP04985  Thymosin beta-4 (TMSB4X) E36
 LDTP02351  Tropomyosin alpha-1 chain (TPM1) D100
 LDTP02351  Tropomyosin alpha-1 chain (TPM1) E97
 LDTP02165  Tropomyosin alpha-3 chain (TPM3) D101
 LDTP02165  Tropomyosin alpha-3 chain (TPM3) E98
 LDTP05068  Tropomyosin alpha-4 chain (TPM4) D64
 LDTP05068  Tropomyosin alpha-4 chain (TPM4) E61
 LDTP02234  Tropomyosin beta chain (TPM2) D100
 LDTP02234  Tropomyosin beta chain (TPM2) E97
 LDTP05034  Ubiquitin-ribosomal protein eL40 fusion protein (UBA52) E24
 LDTP05034  Ubiquitin-ribosomal protein eL40 fusion protein (UBA52) E18
 LDTP05033  Ubiquitin-ribosomal protein eS31 fusion protein (RPS27A) E24
 LDTP05033  Ubiquitin-ribosomal protein eS31 fusion protein (RPS27A) E18

References

1 2H-Azirine-Based Reagents for Chemoselective Bioconjugation at Carboxyl Residues Inside Live Cells. J Am Chem Soc. 2020 Apr 1;142(13):6051-6059. doi: 10.1021/jacs.9b12116. Epub 2020 Mar 23.