Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | Photonaproxen | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | 250 uM | |||||
| Criteria | Qualitation: Labeling site identification | |||||
| Quantitative Method |
Isotope tag
|
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| Experiment Method |
SIM-PAL
|
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| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Bone marrow | ||||
| Disease Model | T acute lymphoblastic leukemia [ICD-11:2A90] | |||||
| Model Name | Human T acute lymphoblastic leukemia cells (Jurkat) | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Sites | ||||
|---|---|---|---|---|---|---|
| LDTP04876 | Actin, cytoplasmic 1 (ACTB) | E100 | ||||
| LDTP04876 | Actin, cytoplasmic 1 (ACTB) | E167 | ||||
| LDTP04876 | Actin, cytoplasmic 1 (ACTB) | H161 | ||||
| LDTP04876 | Actin, cytoplasmic 1 (ACTB) | D24 | ||||
| LDTP04876 | Actin, cytoplasmic 1 (ACTB) | D25 | ||||
| LDTP02198 | Cathepsin D (CTSD) | Y325 | ||||
| LDTP02198 | Cathepsin D (CTSD) | Q322 | ||||
| LDTP15311 | Deaminated glutathione amidase (NIT1) | S286 | ||||
| LDTP02333 | Glutathione S-transferase P (GSTP1) | Y199 | ||||
| LDTP02333 | Glutathione S-transferase P (GSTP1) | P197 | ||||
| LDTP01766 | L-lactate dehydrogenase A chain (LDHA) | E236 | ||||
| LDTP01766 | L-lactate dehydrogenase A chain (LDHA) | V234 | ||||
| LDTP12628 | Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) | Y84 | ||||
| LDTP12628 | Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) | F80 | ||||
| LDTP04284 | Proteasome subunit beta type-3 (PSMB3) | E106 | ||||
| LDTP04284 | Proteasome subunit beta type-3 (PSMB3) | Y104 | ||||
| LDTP09921 | Regulator of nonsense transcripts 1 (UPF1) | R854 | ||||
| LDTP04882 | Ribose-phosphate pyrophosphokinase 1 (PRPS1) | V271 | ||||
| LDTP04265 | Serine--tRNA ligase, cytoplasmic (SARS1) | A189 | ||||
| LDTP00931 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SMARCA5) | Q133 | ||||
| LDTP02640 | X-ray repair cross-complementing protein 6 (XRCC6) | M498 | ||||
| LDTP02640 | X-ray repair cross-complementing protein 6 (XRCC6) | L490 | ||||
Transporter and channel
| Target ID | Target Name | Binding Sites | ||||
|---|---|---|---|---|---|---|
| LDTP05510 | Complement component 1 Q subcomponent-binding protein, mitochondrial (C1QBP) | V172 | ||||
| LDTP01301 | Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial (SLC25A12) | S101 | ||||
| LDTP01295 | Nuclear pore complex protein Nup155 (NUP155) | Q743 | ||||
| LDTP09742 | Protein ELYS (AHCTF1) | S1956 | ||||
| LDTP09742 | Protein ELYS (AHCTF1) | E1950 | ||||
| LDTP04391 | T-complex protein 1 subunit delta (CCT4) | S463 | ||||
| LDTP04391 | T-complex protein 1 subunit delta (CCT4) | N468 | ||||
Transcription factor
| Target ID | Target Name | Binding Sites | ||||
|---|---|---|---|---|---|---|
| LDTP00350 | AT-rich interactive domain-containing protein 1A (ARID1A) | R1046 | ||||
| LDTP14411 | Nascent polypeptide-associated complex subunit alpha, muscle-specific form (NACA) | E1992 | ||||
| LDTP14411 | Nascent polypeptide-associated complex subunit alpha, muscle-specific form (NACA) | I1991 | ||||
Immunoglobulin
| Target ID | Target Name | Binding Sites | ||||
|---|---|---|---|---|---|---|
| LDTP02040 | HLA class I histocompatibility antigen, A alpha chain (HLA-A) | E87 | ||||
Other
| Target ID | Target Name | Binding Sites | ||||
|---|---|---|---|---|---|---|
| LDTP02844 | Histone H1.3 (H1-3) | S42 | ||||
| LDTP07384 | Histone H2A type 2-A (H2AC18; H2AC19) | E57 | ||||
| LDTP07384 | Histone H2A type 2-A (H2AC18; H2AC19) | P49 | ||||
| LDTP07384 | Histone H2A type 2-A (H2AC18; H2AC19) | I63 | ||||
| LDTP08450 | Histone H2A type 2-B (H2AC21) | L56 | ||||
| LDTP08450 | Histone H2A type 2-B (H2AC21) | I63 | ||||
| LDTP08450 | Histone H2A type 2-B (H2AC21) | E62 | ||||
| LDTP08450 | Histone H2A type 2-B (H2AC21) | L59 | ||||
| LDTP08450 | Histone H2A type 2-B (H2AC21) | T60 | ||||
| LDTP01054 | Histone H2B type 1-K (H2BC12) | R73 | ||||
| LDTP01054 | Histone H2B type 1-K (H2BC12) | E72 | ||||
| LDTP01054 | Histone H2B type 1-K (H2BC12) | F71 | ||||
| LDTP06444 | Microtubule-associated protein RP/EB family member 1 (MAPRE1) | I224 | ||||
| LDTP06444 | Microtubule-associated protein RP/EB family member 1 (MAPRE1) | I227 | ||||
| LDTP02164 | Nucleophosmin (NPM1) | E93 | ||||
| LDTP02164 | Nucleophosmin (NPM1) | T86 | ||||
| LDTP06107 | Protein FRG1 (FRG1) | F142 | ||||
| LDTP06107 | Protein FRG1 (FRG1) | P140 | ||||
| LDTP01460 | Protein furry homolog-like (FRYL) | L2752 | ||||
| LDTP06186 | Protein RRP5 homolog (PDCD11) | G1711 | ||||
| LDTP04511 | Rho GDP-dissociation inhibitor 2 (ARHGDIB) | V159 | ||||
| LDTP04511 | Rho GDP-dissociation inhibitor 2 (ARHGDIB) | P158 | ||||
| LDTP05318 | RNA-binding protein EWS (EWSR1) | G465 | ||||
| LDTP05985 | Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) | L2355 | ||||
| LDTP18504 | Thymocyte nuclear protein 1 (THYN1) | E120 | ||||
| LDTP02037 | Tubulin beta-4A chain (TUBB4A) | T218 | ||||
| LDTP02037 | Tubulin beta-4A chain (TUBB4A) | S230 | ||||
| LDTP02037 | Tubulin beta-4A chain (TUBB4A) | T219 | ||||