Details of the Target

General Information of Target

Target ID LDTP13682
Target Name Transcription termination factor 2 (TTF2)
Gene Name TTF2
Gene ID 8458
Synonyms
Transcription termination factor 2; EC 3.6.4.-; Lodestar homolog; RNA polymerase II termination factor; Transcription release factor 2; F2; HuF2
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MGLTKQYLRYVASAVFGVIGSQKGNIVFVTLRGEKGRYVAVPACEHVFIWDLRKGEKILI
LQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGHKAAITTLKYDQLGG
RLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDT
QHCFKTMVGHRTEVWGLVLLSEEKRLITGASDSELRVWDIAYLQEIEDPEEPDPKKIKGS
SPGIQDTLEAEDGAFETDEAPEDRILSCRKAGSIMREGRDRVVNLAVDKTGRILACHGTD
SVLELFCILSKKEIQKKMDKKMKKARKKAKLHSSKGEEEDPEVNVEMSLQDEIQRVTNIK
TSAKIKSFDLIHSPHGELKAVFLLQNNLVELYSLNPSLPTPQPVRTSRITIGGHRSDVRT
LSFSSDNIAVLSAAADSIKIWNRSTLQCIRTMTCEYALCSFFVPGDRQVVIGTKTGKLQL
YDLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVKFWDFELVKDENSTQKRLSV
KQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDIS
HDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKIKQW
DADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLWERTREPLILEEEREMERE
AEYEESVAKEDQPAVPGETQGDSYFTGKKTIETVKAAERIMEAIELYREETAKMKEHKAI
CKAAGKEVPLPSNPILMAYGSISPSAYVLEIFKGIKSSELEESLLVLPFSYVPDILKLFN
EFIQLGSDVELICRCLFFLLRIHFGQITSNQMLVPVIEKLRETTISKVSQVRDVIGFNMA
GLDYLKRECEAKSEVMFFADATSHLEEKKRKRKKREKLILTLT
Target Bioclass
Enzyme
Family
SNF2/RAD54 helicase family
Subcellular location
Cytoplasm
Function
DsDNA-dependent ATPase which acts as a transcription termination factor by coupling ATP hydrolysis with removal of RNA polymerase II from the DNA template. May contribute to mitotic transcription repression. May also be involved in pre-mRNA splicing.
Uniprot ID
Q9UNY4
Ensemble ID
ENST00000369466.9
HGNC ID
HGNC:12398

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
CCLP1 SNV: p.E168G .
DAOY SNV: p.I1066T .
FADU SNV: p.S778L .
HCT116 SNV: p.L783P DBIA    Probe Info 
K562 SNV: p.V128I .
KARPAS299 SNV: p.N270Y .
KASUMI1 SNV: p.T349A .
LS180 Deletion: p.G279DfsTer100 .
MCC13 SNV: p.P745L .
NCIH2122 Substitution: p.K622S .
NCIH23 Deletion: p.W583CfsTer18 .
OVCAR8 SNV: p.V4L .
REH SNV: p.P704S .
RH41 Deletion: p.T724HfsTer6 .
SW756 SNV: p.K1046E .
YSCCC SNV: p.L74V .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 19 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
BTD
 Probe Info  		C759(1.10)  LDD2090  [1]
AHL-Pu-1
 Probe Info  		C759(5.88); C522(2.65)  LDD0168  [2]
Acrolein
 Probe Info  		N.A.  LDD0223  [3]
DBIA
 Probe Info  		C512(1.07); C522(1.07); C224(1.04); C785(0.87)  LDD0078  [4]
ATP probe
 Probe Info  		K1132(0.00); K1133(0.00)  LDD0199  [5]
4-Iodoacetamidophenylacetylene
 Probe Info  		C224(0.00); C785(0.00)  LDD0038  [6]
IA-alkyne
 Probe Info  		C785(0.00); C1118(0.00); C754(0.00)  LDD0036  [6]
Lodoacetamide azide
 Probe Info  		C785(0.00); C37(0.00); C1118(0.00); C204(0.00)  LDD0037  [6]
NAIA_4
 Probe Info  		C224(0.00); C553(0.00)  LDD2226  [7]
DA-P3
 Probe Info  		C224(0.00); C204(0.00)  LDD0178  [8]
Compound 10
 Probe Info  		N.A.  LDD2216  [9]
IPM
 Probe Info  		C759(0.00); C224(0.00)  LDD0005  [10]
TFBX
 Probe Info  		C754(0.00); C553(0.00)  LDD0148  [11]
VSF
 Probe Info  		C224(0.00); C553(0.00)  LDD0007  [10]
Phosphinate-6
 Probe Info  		C224(0.00); C204(0.00)  LDD0018  [12]
Methacrolein
 Probe Info  		N.A.  LDD0218  [3]
W1
 Probe Info  		N.A.  LDD0236  [13]
AOyne
 Probe Info  		10.40  LDD0443  [14]
NAIA_5
 Probe Info  		C50(0.00); C785(0.00); C204(0.00)  LDD2223  [7]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0502  1-(Cyanoacetyl)piperidine MDA-MB-231 C759(0.47)  LDD2095  [1]
 LDCM0025  4SU-RNA HEK-293T C759(5.88); C522(2.65)  LDD0168  [2]
 LDCM0026  4SU-RNA+native RNA DM93 C224(3.23)  LDD0171  [2]
 LDCM0214  AC1 HCT 116 C37(1.10); C512(0.99); C522(1.01); C553(1.05)  LDD0531  [4]
 LDCM0215  AC10 HCT 116 C1118(1.01); C37(0.81); C512(1.21); C522(1.26)  LDD0532  [4]
 LDCM0216  AC100 HCT 116 C37(0.97); C512(1.03); C522(0.98); C553(1.43)  LDD0533  [4]
 LDCM0217  AC101 HCT 116 C37(1.12); C512(1.04); C522(1.06); C553(1.44)  LDD0534  [4]
 LDCM0218  AC102 HCT 116 C37(0.79); C512(1.12); C522(1.10); C553(1.23)  LDD0535  [4]
 LDCM0219  AC103 HCT 116 C37(1.04); C512(1.29); C522(1.28); C553(1.50)  LDD0536  [4]
 LDCM0220  AC104 HCT 116 C37(0.80); C512(1.08); C522(1.06); C553(1.17)  LDD0537  [4]
 LDCM0221  AC105 HCT 116 C37(1.00); C512(1.16); C522(1.15); C553(1.40)  LDD0538  [4]
 LDCM0222  AC106 HCT 116 C37(1.03); C512(1.31); C522(1.29); C553(1.39)  LDD0539  [4]
 LDCM0223  AC107 HCT 116 C37(1.08); C512(1.06); C522(1.03); C553(1.29)  LDD0540  [4]
 LDCM0224  AC108 HCT 116 C37(1.01); C512(1.13); C522(1.26); C553(1.47)  LDD0541  [4]
 LDCM0225  AC109 HCT 116 C37(0.78); C512(1.11); C522(1.14); C553(1.08)  LDD0542  [4]
 LDCM0226  AC11 HCT 116 C1118(0.95); C37(0.82); C512(1.20); C522(1.16)  LDD0543  [4]
 LDCM0227  AC110 HCT 116 C37(1.09); C512(1.30); C522(1.22); C553(1.19)  LDD0544  [4]
 LDCM0228  AC111 HCT 116 C37(1.11); C512(1.29); C522(1.05); C553(1.74)  LDD0545  [4]
 LDCM0229  AC112 HCT 116 C37(0.83); C512(1.32); C522(1.18); C553(1.45)  LDD0546  [4]
 LDCM0230  AC113 HCT 116 C37(0.95); C512(1.08); C522(1.06); C553(1.07)  LDD0547  [4]
 LDCM0231  AC114 HCT 116 C37(0.84); C512(1.18); C522(1.16); C553(0.98)  LDD0548  [4]
 LDCM0232  AC115 HCT 116 C37(0.82); C512(1.21); C522(1.21); C553(0.91)  LDD0549  [4]
 LDCM0233  AC116 HCT 116 C37(0.84); C512(1.36); C522(1.38); C553(1.08)  LDD0550  [4]
 LDCM0234  AC117 HCT 116 C37(1.13); C512(1.07); C522(1.13); C553(0.93)  LDD0551  [4]
 LDCM0235  AC118 HCT 116 C37(0.94); C512(1.04); C522(1.06); C553(0.94)  LDD0552  [4]
 LDCM0236  AC119 HCT 116 C37(1.00); C512(1.17); C522(1.19); C553(0.87)  LDD0553  [4]
 LDCM0237  AC12 HCT 116 C1118(0.91); C37(1.07); C512(1.12); C522(1.16)  LDD0554  [4]
 LDCM0238  AC120 HCT 116 C37(0.96); C512(1.27); C522(1.27); C553(1.02)  LDD0555  [4]
 LDCM0239  AC121 HCT 116 C37(1.19); C512(1.01); C522(1.07); C553(0.97)  LDD0556  [4]
 LDCM0240  AC122 HCT 116 C37(0.95); C512(1.11); C522(1.11); C553(0.96)  LDD0557  [4]
 LDCM0241  AC123 HCT 116 C37(0.92); C512(0.95); C522(0.95); C553(0.86)  LDD0558  [4]
 LDCM0242  AC124 HCT 116 C37(1.07); C512(1.12); C522(1.21); C553(0.96)  LDD0559  [4]
 LDCM0243  AC125 HCT 116 C37(0.99); C512(1.11); C522(1.12); C553(0.97)  LDD0560  [4]
 LDCM0244  AC126 HCT 116 C37(0.96); C512(1.29); C522(1.29); C553(0.97)  LDD0561  [4]
 LDCM0245  AC127 HCT 116 C37(1.04); C512(1.14); C522(1.15); C553(1.00)  LDD0562  [4]
 LDCM0246  AC128 HCT 116 C37(0.39); C512(1.02); C522(1.11); C553(1.05)  LDD0563  [4]
 LDCM0247  AC129 HCT 116 C37(0.39); C512(0.84); C522(0.90); C553(1.17)  LDD0564  [4]
 LDCM0249  AC130 HCT 116 C37(0.44); C512(1.04); C522(1.06); C553(1.28)  LDD0566  [4]
 LDCM0250  AC131 HCT 116 C37(0.41); C512(0.89); C522(0.89); C553(1.12)  LDD0567  [4]
 LDCM0251  AC132 HCT 116 C37(0.42); C512(0.93); C522(0.98); C553(1.40)  LDD0568  [4]
 LDCM0252  AC133 HCT 116 C37(0.41); C512(0.91); C522(0.99); C553(1.40)  LDD0569  [4]
 LDCM0253  AC134 HCT 116 C37(0.46); C512(0.95); C522(1.07); C553(1.44)  LDD0570  [4]
 LDCM0254  AC135 HCT 116 C37(0.51); C512(0.99); C522(1.07); C553(1.13)  LDD0571  [4]
 LDCM0255  AC136 HCT 116 C37(0.45); C512(0.99); C522(1.05); C553(1.39)  LDD0572  [4]
 LDCM0256  AC137 HCT 116 C37(0.43); C512(0.94); C522(0.95); C553(1.36)  LDD0573  [4]
 LDCM0257  AC138 HCT 116 C37(0.55); C512(1.07); C522(1.04); C553(1.61)  LDD0574  [4]
 LDCM0258  AC139 HCT 116 C37(0.53); C512(0.99); C522(1.11); C553(1.54)  LDD0575  [4]
 LDCM0259  AC14 HCT 116 C1118(1.19); C37(1.02); C512(1.05); C522(1.02)  LDD0576  [4]
 LDCM0260  AC140 HCT 116 C37(0.56); C512(1.12); C522(1.15); C553(1.47)  LDD0577  [4]
 LDCM0261  AC141 HCT 116 C37(0.51); C512(1.11); C522(1.09); C553(1.66)  LDD0578  [4]
 LDCM0262  AC142 HCT 116 C37(0.54); C512(0.86); C522(0.85); C553(1.33)  LDD0579  [4]
 LDCM0263  AC143 HCT 116 C553(0.93); C754(1.02); C785(1.04); C512(1.13)  LDD0580  [4]
 LDCM0264  AC144 HCT 116 C553(0.82); C785(0.90); C37(0.94); C754(0.97)  LDD0581  [4]
 LDCM0265  AC145 HCT 116 C754(0.78); C37(0.83); C785(0.98); C553(1.08)  LDD0582  [4]
 LDCM0266  AC146 HCT 116 C754(0.87); C785(0.97); C37(1.03); C553(1.22)  LDD0583  [4]
 LDCM0267  AC147 HCT 116 C37(0.86); C754(0.90); C785(1.04); C553(1.16)  LDD0584  [4]
 LDCM0268  AC148 HCT 116 C754(0.88); C785(0.89); C37(0.92); C553(1.12)  LDD0585  [4]
 LDCM0269  AC149 HCT 116 C785(0.88); C37(0.89); C754(0.91); C553(1.00)  LDD0586  [4]
 LDCM0270  AC15 HCT 116 C553(0.84); C512(1.08); C37(1.09); C785(1.18)  LDD0587  [4]
 LDCM0271  AC150 HCT 116 C553(0.83); C785(0.88); C37(0.99); C754(1.07)  LDD0588  [4]
 LDCM0272  AC151 HCT 116 C553(0.88); C37(0.98); C785(0.99); C754(1.07)  LDD0589  [4]
 LDCM0273  AC152 HCT 116 C785(0.81); C754(0.83); C37(0.98); C553(1.21)  LDD0590  [4]
 LDCM0274  AC153 HCT 116 C785(0.83); C37(0.90); C754(0.98); C553(1.23)  LDD0591  [4]
 LDCM0621  AC154 HCT 116 C37(1.20); C512(1.37); C522(1.44); C553(1.13)  LDD2158  [4]
 LDCM0622  AC155 HCT 116 C37(0.92); C512(1.28); C522(1.35); C553(0.95)  LDD2159  [4]
 LDCM0623  AC156 HCT 116 C37(1.10); C512(1.01); C522(1.13); C553(0.85)  LDD2160  [4]
 LDCM0624  AC157 HCT 116 C37(0.99); C512(1.12); C522(1.10); C553(0.92)  LDD2161  [4]
 LDCM0276  AC17 HCT 116 C754(0.99); C553(1.02); C522(1.02); C512(1.03)  LDD0593  [4]
 LDCM0277  AC18 HCT 116 C37(0.79); C553(0.90); C785(1.13); C754(1.52)  LDD0594  [4]
 LDCM0278  AC19 HCT 116 C37(0.86); C522(1.07); C754(1.10); C512(1.14)  LDD0595  [4]
 LDCM0279  AC2 HCT 116 C512(0.88); C754(0.95); C522(0.97); C37(0.99)  LDD0596  [4]
 LDCM0280  AC20 HCT 116 C37(0.78); C754(0.95); C553(1.06); C512(1.08)  LDD0597  [4]
 LDCM0281  AC21 HCT 116 C37(0.86); C785(0.94); C754(0.98); C553(1.01)  LDD0598  [4]
 LDCM0282  AC22 HCT 116 C37(0.76); C754(0.83); C522(0.97); C553(1.02)  LDD0599  [4]
 LDCM0283  AC23 HCT 116 C37(0.83); C754(0.85); C553(1.09); C785(1.18)  LDD0600  [4]
 LDCM0284  AC24 HCT 116 C522(0.99); C37(1.00); C754(1.00); C512(1.00)  LDD0601  [4]
 LDCM0285  AC25 HCT 116 C754(0.95); C553(1.07); C785(1.07); C522(1.08)  LDD0602  [4]
 LDCM0286  AC26 HCT 116 C754(0.97); C553(0.99); C522(1.14); C512(1.14)  LDD0603  [4]
 LDCM0287  AC27 HCT 116 C754(1.02); C785(1.12); C553(1.14); C522(1.16)  LDD0604  [4]
 LDCM0288  AC28 HCT 116 C754(1.04); C785(1.16); C553(1.16); C522(1.25)  LDD0605  [4]
 LDCM0289  AC29 HCT 116 C754(1.04); C522(1.17); C785(1.18); C512(1.23)  LDD0606  [4]
 LDCM0290  AC3 HCT 116 C512(0.86); C754(0.91); C522(0.93); C553(1.06)  LDD0607  [4]
 LDCM0291  AC30 HCT 116 C754(1.06); C522(1.12); C512(1.15); C785(1.30)  LDD0608  [4]
 LDCM0292  AC31 HCT 116 C512(1.02); C522(1.03); C754(1.05); C553(1.10)  LDD0609  [4]
 LDCM0293  AC32 HCT 116 C754(1.04); C553(1.18); C512(1.26); C522(1.27)  LDD0610  [4]
 LDCM0294  AC33 HCT 116 C553(0.99); C754(1.11); C512(1.16); C522(1.18)  LDD0611  [4]
 LDCM0295  AC34 HCT 116 C553(1.01); C785(1.06); C754(1.25); C522(1.39)  LDD0612  [4]
 LDCM0296  AC35 HCT 116 C754(0.80); C785(0.84); C1118(0.85); C37(0.89)  LDD0613  [4]
 LDCM0297  AC36 HCT 116 C1118(0.89); C754(0.90); C37(0.93); C553(0.95)  LDD0614  [4]
 LDCM0298  AC37 HCT 116 C754(0.85); C1118(0.86); C553(0.93); C522(0.98)  LDD0615  [4]
 LDCM0299  AC38 HCT 116 C754(0.91); C1118(0.97); C553(0.97); C785(1.00)  LDD0616  [4]
 LDCM0300  AC39 HCT 116 C1118(0.87); C754(0.98); C785(1.02); C553(1.05)  LDD0617  [4]
 LDCM0301  AC4 HCT 116 C754(0.94); C512(0.98); C37(1.01); C522(1.04)  LDD0618  [4]
 LDCM0302  AC40 HCT 116 C1118(0.89); C553(0.98); C785(1.08); C37(1.08)  LDD0619  [4]
 LDCM0303  AC41 HCT 116 C1118(0.88); C754(0.95); C553(0.96); C785(0.99)  LDD0620  [4]
 LDCM0304  AC42 HCT 116 C553(0.90); C754(0.94); C1118(0.99); C785(1.07)  LDD0621  [4]
 LDCM0305  AC43 HCT 116 C785(0.98); C754(1.00); C37(1.08); C522(1.17)  LDD0622  [4]
 LDCM0306  AC44 HCT 116 C1118(0.81); C754(0.95); C553(1.00); C785(1.08)  LDD0623  [4]
 LDCM0307  AC45 HCT 116 C1118(0.82); C754(0.97); C553(1.00); C522(1.06)  LDD0624  [4]
 LDCM0308  AC46 HCT 116 C522(0.98); C553(1.00); C37(1.02); C512(1.04)  LDD0625  [4]
 LDCM0309  AC47 HCT 116 C553(0.91); C37(0.99); C1118(0.99); C522(1.01)  LDD0626  [4]
 LDCM0310  AC48 HCT 116 C553(0.84); C1118(0.89); C37(0.94); C785(0.94)  LDD0627  [4]
 LDCM0311  AC49 HCT 116 C1118(1.01); C37(1.02); C553(1.03); C785(1.07)  LDD0628  [4]
 LDCM0312  AC5 HCT 116 C754(0.86); C512(0.93); C522(1.00); C785(1.03)  LDD0629  [4]
 LDCM0313  AC50 HCT 116 C553(0.73); C37(1.02); C785(1.03); C522(1.27)  LDD0630  [4]
 LDCM0314  AC51 HCT 116 C1118(0.79); C553(0.83); C785(0.92); C512(0.99)  LDD0631  [4]
 LDCM0315  AC52 HCT 116 C1118(0.72); C785(0.96); C37(1.02); C553(1.02)  LDD0632  [4]
 LDCM0316  AC53 HCT 116 C785(0.92); C1118(0.95); C553(0.96); C37(0.97)  LDD0633  [4]
 LDCM0317  AC54 HCT 116 C553(0.76); C785(0.96); C37(1.14); C522(1.16)  LDD0634  [4]
 LDCM0318  AC55 HCT 116 C1118(1.09); C37(1.10); C785(1.12); C553(1.15)  LDD0635  [4]
 LDCM0319  AC56 HCT 116 C553(0.76); C785(0.88); C37(1.12); C522(1.55)  LDD0636  [4]
 LDCM0320  AC57 HCT 116 C512(0.92); C522(1.09); C785(1.14); C37(1.20)  LDD0637  [4]
 LDCM0321  AC58 HCT 116 C512(1.03); C785(1.07); C522(1.11); C37(1.43)  LDD0638  [4]
 LDCM0322  AC59 HCT 116 C37(0.97); C785(1.03); C512(1.06); C522(1.18)  LDD0639  [4]
 LDCM0323  AC6 HCT 116 C1118(0.72); C37(0.86); C553(1.03); C785(1.13)  LDD0640  [4]
 LDCM0324  AC60 HCT 116 C512(0.99); C37(1.05); C522(1.12); C785(1.16)  LDD0641  [4]
 LDCM0325  AC61 HCT 116 C512(0.98); C785(1.06); C522(1.10); C37(1.24)  LDD0642  [4]
 LDCM0326  AC62 HCT 116 C37(0.97); C785(1.07); C512(1.11); C522(1.18)  LDD0643  [4]
 LDCM0327  AC63 HCT 116 C37(1.01); C785(1.06); C512(1.09); C522(1.16)  LDD0644  [4]
 LDCM0328  AC64 HCT 116 C37(0.98); C512(0.99); C785(1.09); C522(1.20)  LDD0645  [4]
 LDCM0329  AC65 HCT 116 C512(1.03); C785(1.15); C522(1.19); C37(1.20)  LDD0646  [4]
 LDCM0330  AC66 HCT 116 C512(1.04); C37(1.13); C785(1.13); C522(1.19)  LDD0647  [4]
 LDCM0331  AC67 HCT 116 C37(0.95); C785(1.06); C512(1.24); C522(1.46)  LDD0648  [4]
 LDCM0332  AC68 HCT 116 C37(0.96); C553(0.99); C522(1.11); C785(1.14)  LDD0649  [4]
 LDCM0333  AC69 HCT 116 C37(0.74); C553(0.90); C785(1.09); C512(1.18)  LDD0650  [4]
 LDCM0334  AC7 HCT 116 C553(0.83); C37(0.89); C1118(0.97); C512(1.04)  LDD0651  [4]
 LDCM0335  AC70 HCT 116 C553(0.91); C37(0.92); C522(1.17); C512(1.38)  LDD0652  [4]
 LDCM0336  AC71 HCT 116 C37(0.76); C553(0.97); C512(1.06); C785(1.11)  LDD0653  [4]
 LDCM0337  AC72 HCT 116 C37(0.83); C553(1.05); C785(1.16); C522(1.23)  LDD0654  [4]
 LDCM0338  AC73 HCT 116 C553(1.14); C37(1.20); C512(1.54); C522(1.60)  LDD0655  [4]
 LDCM0339  AC74 HCT 116 C553(0.87); C37(1.06); C512(1.28); C785(1.46)  LDD0656  [4]
 LDCM0340  AC75 HCT 116 C37(0.98); C553(1.09); C785(1.44); C512(1.79)  LDD0657  [4]
 LDCM0341  AC76 HCT 116 C37(0.93); C553(1.26); C522(1.26); C512(1.32)  LDD0658  [4]
 LDCM0342  AC77 HCT 116 C553(0.90); C37(1.03); C522(1.31); C512(1.31)  LDD0659  [4]
 LDCM0343  AC78 HCT 116 C553(0.75); C37(0.96); C522(1.09); C785(1.18)  LDD0660  [4]
 LDCM0344  AC79 HCT 116 C37(0.85); C553(1.07); C512(1.19); C522(1.34)  LDD0661  [4]
 LDCM0345  AC8 HCT 116 C553(0.81); C37(0.88); C1118(0.91); C785(1.13)  LDD0662  [4]
 LDCM0346  AC80 HCT 116 C37(0.84); C553(0.97); C522(1.03); C785(1.14)  LDD0663  [4]
 LDCM0347  AC81 HCT 116 C37(0.81); C785(0.90); C522(1.01); C512(1.09)  LDD0664  [4]
 LDCM0348  AC82 HCT 116 C37(0.90); C553(1.06); C785(1.72); C512(1.76)  LDD0665  [4]
 LDCM0349  AC83 HCT 116 C1118(0.89); C37(1.05); C512(1.17); C785(1.26)  LDD0666  [4]
 LDCM0350  AC84 HCT 116 C1118(1.06); C37(1.09); C785(1.14); C553(1.18)  LDD0667  [4]
 LDCM0351  AC85 HCT 116 C37(0.96); C1118(1.02); C785(1.03); C553(1.14)  LDD0668  [4]
 LDCM0352  AC86 HCT 116 C37(0.74); C785(1.11); C1118(1.20); C553(1.24)  LDD0669  [4]
 LDCM0353  AC87 HCT 116 C785(0.96); C522(1.08); C512(1.16); C37(1.24)  LDD0670  [4]
 LDCM0354  AC88 HCT 116 C1118(0.89); C785(1.07); C522(1.15); C37(1.22)  LDD0671  [4]
 LDCM0355  AC89 HCT 116 C1118(0.98); C522(1.06); C37(1.06); C512(1.26)  LDD0672  [4]
 LDCM0357  AC90 HCT 116 C37(0.91); C522(1.02); C1118(1.04); C512(1.19)  LDD0674  [4]
 LDCM0358  AC91 HCT 116 C37(1.00); C1118(1.02); C512(1.31); C553(1.40)  LDD0675  [4]
 LDCM0359  AC92 HCT 116 C1118(0.83); C37(1.04); C553(1.28); C522(1.35)  LDD0676  [4]
 LDCM0360  AC93 HCT 116 C1118(0.79); C785(0.94); C37(0.95); C553(0.99)  LDD0677  [4]
 LDCM0361  AC94 HCT 116 C37(0.97); C1118(0.98); C785(0.98); C553(1.01)  LDD0678  [4]
 LDCM0362  AC95 HCT 116 C1118(1.14); C522(1.19); C553(1.26); C37(1.27)  LDD0679  [4]
 LDCM0363  AC96 HCT 116 C37(0.81); C1118(1.13); C522(1.17); C785(1.26)  LDD0680  [4]
 LDCM0364  AC97 HCT 116 C1118(0.90); C785(1.07); C37(1.11); C553(1.26)  LDD0681  [4]
 LDCM0365  AC98 HCT 116 C754(0.95); C37(1.21); C785(1.31); C553(1.51)  LDD0682  [4]
 LDCM0366  AC99 HCT 116 C754(0.60); C785(0.87); C37(0.96); C522(1.04)  LDD0683  [4]
 LDCM0248  AKOS034007472 HCT 116 C1118(0.92); C37(1.10); C512(1.08); C522(1.09)  LDD0565  [4]
 LDCM0356  AKOS034007680 HCT 116 C553(0.78); C1118(0.87); C785(1.07); C512(1.07)  LDD0673  [4]
 LDCM0275  AKOS034007705 HCT 116 C553(0.79); C37(0.79); C785(1.23); C1118(1.25)  LDD0592  [4]
 LDCM0020  ARS-1620 HCC44 C512(1.07); C522(1.07); C224(1.04); C785(0.87)  LDD0078  [4]
 LDCM0087  Capsaicin HEK-293T 8.34  LDD0185  [8]
 LDCM0632  CL-Sc Hep-G2 C204(0.43)  LDD2227  [7]
 LDCM0367  CL1 HCT 116 C785(0.88); C522(0.95); C553(0.97); C754(1.09)  LDD0684  [4]
 LDCM0368  CL10 HCT 116 C553(0.96); C754(1.03); C37(1.07); C512(1.08)  LDD0685  [4]
 LDCM0369  CL100 HCT 116 C754(0.80); C512(1.00); C785(1.01); C522(1.05)  LDD0686  [4]
 LDCM0370  CL101 HCT 116 C553(0.77); C37(0.84); C1118(0.85); C785(1.09)  LDD0687  [4]
 LDCM0371  CL102 HCT 116 C553(0.86); C37(0.94); C754(0.95); C1118(1.07)  LDD0688  [4]
 LDCM0372  CL103 HCT 116 C553(0.76); C37(0.81); C754(0.96); C1118(1.02)  LDD0689  [4]
 LDCM0373  CL104 HCT 116 C553(0.89); C754(0.91); C1118(0.96); C512(1.05)  LDD0690  [4]
 LDCM0374  CL105 HCT 116 C553(0.80); C37(1.02); C754(1.19); C522(1.19)  LDD0691  [4]
 LDCM0375  CL106 HCT 116 C37(0.81); C553(0.92); C785(1.29); C522(1.33)  LDD0692  [4]
 LDCM0376  CL107 HCT 116 C37(0.85); C553(0.92); C512(1.25); C785(1.28)  LDD0693  [4]
 LDCM0377  CL108 HCT 116 C37(0.87); C553(0.98); C785(1.17); C512(1.36)  LDD0694  [4]
 LDCM0378  CL109 HCT 116 C37(0.94); C553(0.95); C785(1.05); C754(1.10)  LDD0695  [4]
 LDCM0379  CL11 HCT 116 C553(0.98); C37(1.04); C754(1.07); C785(1.26)  LDD0696  [4]
 LDCM0380  CL110 HCT 116 C37(0.86); C553(1.04); C785(1.30); C754(1.40)  LDD0697  [4]
 LDCM0381  CL111 HCT 116 C37(0.98); C553(1.09); C785(1.10); C754(1.12)  LDD0698  [4]
 LDCM0382  CL112 HCT 116 C754(0.93); C785(1.06); C553(1.14); C522(1.38)  LDD0699  [4]
 LDCM0383  CL113 HCT 116 C754(1.05); C785(1.06); C553(1.10); C522(1.31)  LDD0700  [4]
 LDCM0384  CL114 HCT 116 C754(0.97); C553(1.17); C785(1.23); C512(1.40)  LDD0701  [4]
 LDCM0385  CL115 HCT 116 C754(1.00); C553(1.09); C785(1.10); C512(1.18)  LDD0702  [4]
 LDCM0386  CL116 HCT 116 C754(1.03); C553(1.09); C512(1.14); C785(1.14)  LDD0703  [4]
 LDCM0387  CL117 HCT 116 C1118(0.93); C785(1.04); C553(1.05); C37(1.11)  LDD0704  [4]
 LDCM0388  CL118 HCT 116 C37(0.80); C1118(0.96); C553(0.99); C754(1.01)  LDD0705  [4]
 LDCM0389  CL119 HCT 116 C1118(0.95); C37(0.96); C785(1.00); C553(1.04)  LDD0706  [4]
 LDCM0390  CL12 HCT 116 C553(1.00); C754(1.02); C512(1.10); C37(1.19)  LDD0707  [4]
 LDCM0391  CL120 HCT 116 C754(0.97); C1118(0.97); C785(1.02); C553(1.03)  LDD0708  [4]
 LDCM0392  CL121 HCT 116 C1118(0.80); C785(0.93); C37(1.01); C553(1.04)  LDD0709  [4]
 LDCM0393  CL122 HCT 116 C553(0.72); C785(0.93); C37(0.96); C522(1.09)  LDD0710  [4]
 LDCM0394  CL123 HCT 116 C553(0.80); C785(0.95); C37(0.98); C1118(1.36)  LDD0711  [4]
 LDCM0395  CL124 HCT 116 C553(0.83); C785(0.93); C37(0.97); C1118(1.06)  LDD0712  [4]
 LDCM0396  CL125 HCT 116 C754(0.98); C512(1.00); C37(1.00); C785(1.01)  LDD0713  [4]
 LDCM0397  CL126 HCT 116 C785(0.92); C512(0.99); C522(1.01); C754(1.08)  LDD0714  [4]
 LDCM0398  CL127 HCT 116 C512(0.89); C522(0.99); C785(1.01); C754(1.16)  LDD0715  [4]
 LDCM0399  CL128 HCT 116 C512(0.99); C522(1.04); C785(1.07); C37(1.07)  LDD0716  [4]
 LDCM0400  CL13 HCT 116 C512(0.86); C553(0.95); C522(0.97); C754(1.01)  LDD0717  [4]
 LDCM0401  CL14 HCT 116 C512(0.96); C522(1.00); C553(1.00); C37(1.03)  LDD0718  [4]
 LDCM0402  CL15 HCT 116 C754(1.02); C512(1.07); C37(1.09); C522(1.15)  LDD0719  [4]
 LDCM0403  CL16 HCT 116 C754(0.73); C1118(0.93); C522(0.99); C512(1.01)  LDD0720  [4]
 LDCM0404  CL17 HCT 116 C37(0.74); C754(0.86); C1118(0.90); C553(0.99)  LDD0721  [4]
 LDCM0405  CL18 HCT 116 C553(0.85); C512(0.98); C1118(0.98); C785(1.02)  LDD0722  [4]
 LDCM0406  CL19 HCT 116 C37(0.82); C522(0.83); C785(0.90); C553(0.94)  LDD0723  [4]
 LDCM0407  CL2 HCT 116 C522(0.91); C553(0.95); C754(0.95); C785(0.95)  LDD0724  [4]
 LDCM0408  CL20 HCT 116 C37(0.80); C1118(0.96); C553(0.96); C522(0.98)  LDD0725  [4]
 LDCM0409  CL21 HCT 116 C754(0.72); C1118(0.86); C553(0.99); C785(1.09)  LDD0726  [4]
 LDCM0410  CL22 HCT 116 C754(0.50); C37(0.71); C1118(0.87); C553(0.89)  LDD0727  [4]
 LDCM0411  CL23 HCT 116 C522(0.87); C37(0.91); C553(0.93); C1118(0.93)  LDD0728  [4]
 LDCM0412  CL24 HCT 116 C1118(1.20); C37(0.77); C512(1.16); C522(1.11)  LDD0729  [4]
 LDCM0413  CL25 HCT 116 C1118(0.90); C37(0.94); C512(1.31); C522(1.12)  LDD0730  [4]
 LDCM0414  CL26 HCT 116 C1118(0.88); C37(1.01); C512(1.09); C522(0.93)  LDD0731  [4]
 LDCM0415  CL27 HCT 116 C1118(1.01); C37(0.91); C512(0.97); C522(0.82)  LDD0732  [4]
 LDCM0416  CL28 HCT 116 C1118(0.92); C37(0.84); C512(1.07); C522(0.84)  LDD0733  [4]
 LDCM0417  CL29 HCT 116 C1118(0.99); C37(0.88); C512(1.02); C522(0.93)  LDD0734  [4]
 LDCM0418  CL3 HCT 116 C37(1.01); C512(1.04); C522(0.90); C553(0.93)  LDD0735  [4]
 LDCM0419  CL30 HCT 116 C1118(0.90); C37(0.77); C512(1.04); C522(0.90)  LDD0736  [4]
 LDCM0420  CL31 HCT 116 C37(0.98); C512(1.06); C522(0.90); C553(1.08)  LDD0737  [4]
 LDCM0421  CL32 HCT 116 C37(0.97); C512(1.08); C522(1.00); C553(1.18)  LDD0738  [4]
 LDCM0422  CL33 HCT 116 C37(1.08); C512(1.22); C522(1.21); C553(1.34)  LDD0739  [4]
 LDCM0423  CL34 HCT 116 C37(1.10); C512(0.92); C522(1.14); C553(1.05)  LDD0740  [4]
 LDCM0424  CL35 HCT 116 C37(1.20); C512(1.03); C522(1.10); C553(1.10)  LDD0741  [4]
 LDCM0425  CL36 HCT 116 C37(1.19); C512(1.09); C522(1.09); C553(1.18)  LDD0742  [4]
 LDCM0426  CL37 HCT 116 C37(1.30); C512(0.98); C522(1.01); C553(1.46)  LDD0743  [4]
 LDCM0428  CL39 HCT 116 C37(1.22); C512(1.05); C522(1.02); C553(1.15)  LDD0745  [4]
 LDCM0429  CL4 HCT 116 C37(0.98); C512(1.50); C522(1.05); C553(1.44)  LDD0746  [4]
 LDCM0430  CL40 HCT 116 C37(1.07); C512(1.37); C522(1.13); C553(1.22)  LDD0747  [4]
 LDCM0431  CL41 HCT 116 C37(1.17); C512(1.01); C522(1.07); C553(1.23)  LDD0748  [4]
 LDCM0432  CL42 HCT 116 C37(1.31); C512(0.94); C522(1.41); C553(1.21)  LDD0749  [4]
 LDCM0433  CL43 HCT 116 C37(1.21); C512(0.99); C522(1.20); C553(1.26)  LDD0750  [4]
 LDCM0434  CL44 HCT 116 C37(1.18); C512(0.96); C522(1.11); C553(1.12)  LDD0751  [4]
 LDCM0435  CL45 HCT 116 C37(1.31); C512(0.97); C522(1.39); C553(1.47)  LDD0752  [4]
 LDCM0436  CL46 HCT 116 C37(0.98); C512(1.11); C522(1.00); C754(0.62)  LDD0753  [4]
 LDCM0437  CL47 HCT 116 C37(0.95); C512(0.97); C522(0.97); C754(0.78)  LDD0754  [4]
 LDCM0438  CL48 HCT 116 C37(0.96); C512(0.96); C522(0.95); C754(0.68)  LDD0755  [4]
 LDCM0439  CL49 HCT 116 C37(0.92); C512(0.95); C522(0.95); C754(0.83)  LDD0756  [4]
 LDCM0440  CL5 HCT 116 C37(1.12); C512(1.00); C522(0.93); C553(0.93)  LDD0757  [4]
 LDCM0441  CL50 HCT 116 C37(1.10); C512(1.04); C522(0.96); C754(0.89)  LDD0758  [4]
 LDCM0442  CL51 HCT 116 C37(0.86); C512(1.11); C522(0.96); C754(0.95)  LDD0759  [4]
 LDCM0443  CL52 HCT 116 C37(0.98); C512(1.20); C522(1.14); C754(0.72)  LDD0760  [4]
 LDCM0444  CL53 HCT 116 C37(0.89); C512(1.05); C522(0.92); C754(0.71)  LDD0761  [4]
 LDCM0445  CL54 HCT 116 C37(1.02); C512(1.04); C522(0.77); C754(0.81)  LDD0762  [4]
 LDCM0446  CL55 HCT 116 C37(1.01); C512(1.09); C522(0.89); C754(0.95)  LDD0763  [4]
 LDCM0447  CL56 HCT 116 C37(1.03); C512(0.87); C522(0.98); C754(1.09)  LDD0764  [4]
 LDCM0448  CL57 HCT 116 C37(0.86); C512(0.91); C522(1.07); C754(1.18)  LDD0765  [4]
 LDCM0449  CL58 HCT 116 C37(0.97); C512(1.08); C522(0.94); C754(0.80)  LDD0766  [4]
 LDCM0450  CL59 HCT 116 C37(0.91); C512(0.87); C522(1.00); C754(0.75)  LDD0767  [4]
 LDCM0451  CL6 HCT 116 C37(0.97); C512(1.04); C522(1.10); C553(0.95)  LDD0768  [4]
 LDCM0452  CL60 HCT 116 C37(0.92); C512(0.94); C522(1.09); C754(0.89)  LDD0769  [4]
 LDCM0453  CL61 HCT 116 C37(1.18); C512(1.09); C522(1.15); C553(1.09)  LDD0770  [4]
 LDCM0454  CL62 HCT 116 C37(1.16); C512(1.05); C522(0.87); C553(1.02)  LDD0771  [4]
 LDCM0455  CL63 HCT 116 C37(1.22); C512(1.09); C522(0.99); C553(1.02)  LDD0772  [4]
 LDCM0456  CL64 HCT 116 C37(0.98); C512(0.95); C522(1.12); C553(1.35)  LDD0773  [4]
 LDCM0457  CL65 HCT 116 C37(0.91); C512(1.04); C522(1.01); C553(1.12)  LDD0774  [4]
 LDCM0458  CL66 HCT 116 C37(0.92); C512(0.89); C522(1.22); C553(1.29)  LDD0775  [4]
 LDCM0459  CL67 HCT 116 C37(0.96); C512(1.14); C522(1.24); C553(1.09)  LDD0776  [4]
 LDCM0460  CL68 HCT 116 C37(0.83); C512(0.97); C522(1.13); C553(0.98)  LDD0777  [4]
 LDCM0461  CL69 HCT 116 C37(0.98); C512(1.12); C522(1.01); C553(1.05)  LDD0778  [4]
 LDCM0462  CL7 HCT 116 C37(1.01); C512(0.89); C522(0.97); C553(0.98)  LDD0779  [4]
 LDCM0463  CL70 HCT 116 C37(0.76); C512(1.05); C522(1.14); C553(0.97)  LDD0780  [4]
 LDCM0464  CL71 HCT 116 C37(1.28); C512(1.21); C522(1.21); C553(1.10)  LDD0781  [4]
 LDCM0465  CL72 HCT 116 C37(1.20); C512(1.07); C522(0.86); C553(1.08)  LDD0782  [4]
 LDCM0466  CL73 HCT 116 C37(1.19); C512(0.93); C522(1.07); C553(1.17)  LDD0783  [4]
 LDCM0467  CL74 HCT 116 C37(0.96); C512(1.05); C522(1.14); C553(1.04)  LDD0784  [4]
 LDCM0469  CL76 HCT 116 C512(1.01); C522(1.04); C553(0.97); C754(0.76)  LDD0786  [4]
 LDCM0470  CL77 HCT 116 C512(1.17); C522(1.12); C553(0.95); C754(0.90)  LDD0787  [4]
 LDCM0471  CL78 HCT 116 C512(1.21); C522(1.19); C553(1.03); C754(0.95)  LDD0788  [4]
 LDCM0472  CL79 HCT 116 C512(1.15); C522(1.18); C553(1.02); C754(0.92)  LDD0789  [4]
 LDCM0473  CL8 HCT 116 C37(1.05); C512(3.20); C522(2.36); C553(0.94)  LDD0790  [4]
 LDCM0474  CL80 HCT 116 C512(0.87); C522(0.93); C553(1.09); C754(0.98)  LDD0791  [4]
 LDCM0475  CL81 HCT 116 C512(1.05); C522(1.12); C553(1.10); C754(0.87)  LDD0792  [4]
 LDCM0476  CL82 HCT 116 C512(1.37); C522(1.43); C553(0.95); C754(0.84)  LDD0793  [4]
 LDCM0477  CL83 HCT 116 C512(1.35); C522(1.37); C553(1.09); C754(0.95)  LDD0794  [4]
 LDCM0478  CL84 HCT 116 C512(1.60); C522(1.58); C553(1.02); C754(0.94)  LDD0795  [4]
 LDCM0479  CL85 HCT 116 C512(1.08); C522(1.10); C553(0.89); C754(0.84)  LDD0796  [4]
 LDCM0480  CL86 HCT 116 C512(0.93); C522(1.00); C553(1.03); C754(0.93)  LDD0797  [4]
 LDCM0481  CL87 HCT 116 C512(1.15); C522(1.14); C553(0.93); C754(0.80)  LDD0798  [4]
 LDCM0482  CL88 HCT 116 C512(1.27); C522(1.22); C553(0.85); C754(0.81)  LDD0799  [4]
 LDCM0483  CL89 HCT 116 C512(1.74); C522(1.69); C553(1.14); C754(0.88)  LDD0800  [4]
 LDCM0484  CL9 HCT 116 C37(1.08); C512(1.06); C522(0.92); C553(1.00)  LDD0801  [4]
 LDCM0485  CL90 HCT 116 C512(1.27); C522(1.43); C553(1.29); C754(1.06)  LDD0802  [4]
 LDCM0486  CL91 HCT 116 C37(0.96); C512(1.06); C522(1.11); C553(0.89)  LDD0803  [4]
 LDCM0487  CL92 HCT 116 C37(0.97); C512(1.09); C522(1.10); C553(0.98)  LDD0804  [4]
 LDCM0488  CL93 HCT 116 C37(0.90); C512(0.92); C522(0.92); C553(1.00)  LDD0805  [4]
 LDCM0489  CL94 HCT 116 C37(0.85); C512(1.35); C522(1.36); C553(1.12)  LDD0806  [4]
 LDCM0490  CL95 HCT 116 C37(1.11); C512(1.58); C522(1.96); C553(1.27)  LDD0807  [4]
 LDCM0491  CL96 HCT 116 C37(1.04); C512(1.07); C522(1.08); C553(1.15)  LDD0808  [4]
 LDCM0492  CL97 HCT 116 C37(1.00); C512(0.99); C522(1.03); C553(1.03)  LDD0809  [4]
 LDCM0493  CL98 HCT 116 C37(1.01); C512(1.09); C522(1.12); C553(1.22)  LDD0810  [4]
 LDCM0494  CL99 HCT 116 C37(1.17); C512(1.12); C522(1.14); C553(1.00)  LDD0811  [4]
 LDCM0634  CY-0357 Hep-G2 C204(0.35)  LDD2228  [7]
 LDCM0495  E2913 HEK-293T C224(1.04); C204(0.89); C37(1.08); C754(1.00)  LDD1698  [15]
 LDCM0625  F8 Ramos C224(1.09); C1118(0.51); C553(1.13)  LDD2187  [16]
 LDCM0572  Fragment10 Ramos C224(1.79); C1118(1.12); C553(1.20)  LDD2189  [16]
 LDCM0573  Fragment11 Ramos C224(6.54); C1118(0.01)  LDD2190  [16]
 LDCM0574  Fragment12 Ramos C224(0.86); C1118(0.74); C553(1.53)  LDD2191  [16]
 LDCM0575  Fragment13 Ramos C224(0.98); C1118(0.73)  LDD2192  [16]
 LDCM0576  Fragment14 Ramos C224(1.38); C1118(0.91)  LDD2193  [16]
 LDCM0579  Fragment20 Ramos C224(0.86); C553(1.28)  LDD2194  [16]
 LDCM0580  Fragment21 Ramos C224(0.83); C1118(1.00); C553(0.88)  LDD2195  [16]
 LDCM0582  Fragment23 Ramos C224(1.43); C1118(0.75); C553(0.82)  LDD2196  [16]
 LDCM0578  Fragment27 Ramos C224(0.83); C1118(1.12); C553(1.28)  LDD2197  [16]
 LDCM0586  Fragment28 Ramos C224(0.52); C1118(0.85); C553(0.76)  LDD2198  [16]
 LDCM0588  Fragment30 Ramos C224(1.13); C1118(8.28); C553(0.62)  LDD2199  [16]
 LDCM0589  Fragment31 Ramos C224(1.12); C1118(0.96)  LDD2200  [16]
 LDCM0590  Fragment32 Ramos C224(2.11); C1118(0.90); C553(1.28)  LDD2201  [16]
 LDCM0468  Fragment33 HCT 116 C37(1.10); C512(0.92); C522(1.04); C553(1.00)  LDD0785  [4]
 LDCM0596  Fragment38 Ramos C224(0.99); C1118(0.83)  LDD2203  [16]
 LDCM0566  Fragment4 Ramos C224(1.04); C1118(0.18); C553(2.66)  LDD2184  [16]
 LDCM0427  Fragment51 HCT 116 C37(1.10); C512(2.56); C522(1.69); C553(1.76)  LDD0744  [4]
 LDCM0610  Fragment52 Ramos C224(1.27); C1118(1.28)  LDD2204  [16]
 LDCM0614  Fragment56 Ramos C224(1.74); C1118(1.19); C553(0.83)  LDD2205  [16]
 LDCM0569  Fragment7 Ramos C224(1.39); C553(1.73)  LDD2186  [16]
 LDCM0571  Fragment9 Ramos C224(1.24); C1118(0.72)  LDD2188  [16]
 LDCM0022  KB02 HCT 116 C522(3.08); C785(2.16); C754(2.30); C224(1.72)  LDD0080  [4]
 LDCM0023  KB03 HCT 116 C522(1.67); C785(4.15); C754(2.58); C224(0.99)  LDD0081  [4]
 LDCM0024  KB05 HCT 116 C522(5.91); C785(2.01); C754(1.71); C224(1.59)  LDD0082  [4]
 LDCM0109  NEM HeLa N.A.  LDD0223  [3]
 LDCM0497  Nucleophilic fragment 11b MDA-MB-231 C759(1.10)  LDD2090  [1]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C759(0.96)  LDD2146  [1]
 LDCM0559  Nucleophilic fragment 9b MDA-MB-231 C759(1.40)  LDD2153  [1]
 LDCM0032  Oleacein HEK-293T 9.42  LDD0184  [8]
 LDCM0029  Quercetin HEK-293T 4.23  LDD0181  [8]
 LDCM0021  THZ1 HCT 116 C512(0.99); C522(0.99); C785(0.91)  LDD2173  [4]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Transcription factor
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cell division cycle 5-like protein (CDC5L) CEF1 family Q99459
Glucocorticoid modulatory element-binding protein 2 (GMEB2) . Q9UKD1
Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
TNFAIP3-interacting protein 1 (TNIP1) . Q15025

References

1 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
2 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
3 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
4 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
5 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
6 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
7 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
8 A chemical probe unravels the reactive proteome of health-associated catechols. Chem Sci. 2023 Jul 22;14(32):8635-8643. doi: 10.1039/d3sc00888f. eCollection 2023 Aug 16.
Mass spectrometry data entry: PXD043348
9 Multiplexed CuAAC Suzuki-Miyaura Labeling for Tandem Activity-Based Chemoproteomic Profiling. Anal Chem. 2021 Feb 2;93(4):2610-2618. doi: 10.1021/acs.analchem.0c04726. Epub 2021 Jan 20.
Mass spectrometry data entry: PXD022279
10 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
11 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
12 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
13 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
14 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
15 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
16 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578