Details of the Probe

General Information of Probe

Probe ID
LDPC0688
Probe Name
JN939;JN942;JN945;JN938;JN940;JN849

The Probe Interaction Atlas

Target(s) List of this Probe

11 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (AGPAT3) LDTP12551 A194  LDD0115 
Actin, cytoplasmic 1 (ACTB) LDTP04876 V96; A97; E100  LDD0115 
E3 ubiquitin-protein ligase UBR3 (UBR3) LDTP07830 E1730; G1732  LDD0115 
Electron transfer flavoprotein subunit beta (ETFB) LDTP03849 G33; V34  LDD0115 
Endoplasmic reticulum chaperone BiP (HSPA5) LDTP02534 V465; Y466; E467  LDD0115 
Minor histocompatibility antigen H13 (HM13) LDTP09396 N62; A63; S64; D65  LDD0115 
Myosin-10 (MYH10) LDTP03765 V774; L775  LDD0115 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 A338; L339; G341; L342  LDD0115 
Triple functional domain protein (TRIO) LDTP01368 Q1815  LDD0115 
Ubiquitin carboxyl-terminal hydrolase 24 (USP24) LDTP13720 A811  LDD0115 
Ubiquitin carboxyl-terminal hydrolase 42 (USP42) LDTP12099 E1248; D1249  LDD0115 
------------------------------------------------------------------------------------
⏷ Show the Full List of 11 Enzyme
3 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Lysosome membrane protein 2 (SCARB2) LDTP06034 V140; I144; H150  LDD0115 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 Q94  LDD0115 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 V164; V171  LDD0115 
------------------------------------------------------------------------------------
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Zinc finger MYM-type protein 3 (ZMYM3) LDTP06081 T310; C311; C314  LDD0115 
------------------------------------------------------------------------------------
14 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Desmin (DES) LDTP02913 E387; Y388; Q389; K395  LDD0115 
Dynein axonemal heavy chain 2 (DNAH2) LDTP13014 D1485  LDD0115 
ELKS/Rab6-interacting/CAST family member 1 (ERC1) LDTP08448 Q470; Q473; E474; L475  LDD0115 
Endoplasmin (HSP90B1) LDTP02734 A664; L494; G495  LDD0115 
Glial fibrillary acidic protein (GFAP) LDTP02710 G301; T302  LDD0115 
Histone H2B type 1-M (H2BC14) LDTP11000 E114  LDD0115 
Histone H4 (H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16) LDTP05004 V71; D69  LDD0115 
Nucleophosmin (NPM1) LDTP02164 S88; Q84; G91; V33  LDD0115 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 E97; F95  LDD0115 
POTE ankyrin domain family member F (POTEF) LDTP14342 A722; D724  LDD0115 
Prohibitin-2 (PHB2) LDTP10924 F41; S39  LDD0115 
Reticulon-4 (RTN4) LDTP12412 L1168; Y1091; N1093; V1099  LDD0115 
Tetratricopeptide repeat protein 5 (TTC5) LDTP08738 D45  LDD0115 
Vimentin (VIM) LDTP02297 E198; E346; V353; I130  LDD0115 
------------------------------------------------------------------------------------
⏷ Show the Full List of 14 Other

Full Information of The Labelling Profiles of This Probe

Qualitation: Labeling site identification
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
all probe:10 uM
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Adrenal
Disease Model
Neuroblastoma [ICD-11:2D50]
Model Name
Human neuroblastoma cells (SK-N-SH)
Interaction Atlas ID
 LDD0115 
Download The Altas

References

1 Labeling Preferences of Diazirines with Protein Biomolecules. J Am Chem Soc. 2021 May 5;143(17):6691-6700. doi: 10.1021/jacs.1c02509. Epub 2021 Apr 20.
Mass spectrometry data entry: PXD025140