Details of the Target

General Information of Target

Target ID LDTP06081
Target Name Zinc finger MYM-type protein 3 (ZMYM3)
Gene Name ZMYM3
Gene ID 9203
Synonyms
DXS6673E; KIAA0385; ZNF261; Zinc finger MYM-type protein 3; Zinc finger protein 261
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MDPSDFPSPFDPLTLPEKPLAGDLPVDMEFGEDLLESQTAPTRGWAPPGPSPSSGALDLL
DTPAGLEKDPGVLDGATELLGLGGLLYKAPSPPEVDHGPEGTLAWDAGDQTLEPGPGGQT
PEVVPPDPGAGANSCSPEGLLEPLAPDSPITLQSPHIEEEETTSIATARRGSPGQEEELP
QGQPQSPNAPPSPSVGETLGDGINSSQTKPGGSSPPAHPSLPGDGLTAKASEKPPERKRS
ERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMSLRSSVSQRA
GRSAVGTKMTCAHCRTPLQKGQTAYQRKGLPQLFCSSSCLTTFSKKPSGKKTCTFCKKEI
WNTKDSVVAQTGSGGSFHEFCTSVCLSLYEAQQQRPIPQSGDPADATRCSICQKTGEVLH
EVSNGSVVHRLCSDSCFSKFRANKGLKTNCCDQCGAYIYTKTGSPGPELLFHEGQQKRFC
NTTCLGAYKKKNTRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSYKVKQAGLT
GPPRPCSFCRRSLSDPCYYNKVDRTVYQFCSPSCWTKFQRTSPEGGIHLSCHYCHSLFSG
KPEVLDWQDQVFQFCCRDCCEDFKRLRGVVSQCEHCRQEKLLHEKLRFSGVEKSFCSEGC
VLLYKQDFTKKLGLCCITCTYCSQTCQRGVTEQLDGSTWDFCSEDCKSKYLLWYCKAARC
HACKRQGKLLETIHWRGQIRHFCNQQCLLRFYSQQNQPNLDTQSGPESLLNSQSPESKPQ
TPSQTKVENSNTVRTPEENGNLGKIPVKTRSAPTAPTPPPPPPPATPRKNKAAMCKPLMQ
NRGVSCKVEMKSKGSQTEEWKPQVIVLPIPVPIFVPVPMHLYCQKVPVPFSMPIPVPVPM
FLPTTLESTDKIVETIEELKVKIPSNPLEADILAMAEMIAEAEELDKASSDLCDLVSNQS
AEGLLEDCDLFGPARDDVLAMAVKMANVLDEPGQDLEADFPKNPLDINPSVDFLFDCGLV
GPEDVSTEQDLPRTMRKGQKRLVLSESCSRDSMSSQPSCTGLNYSYGVNAWKCWVQSKYA
NGETSKGDELRFGPKPMRIKEDILACSAAELNYGLAQFVREITRPNGERYEPDSIYYLCL
GIQQYLLENNRMVNIFTDLYYLTFVQELNKSLSTWQPTLLPNNTVFSRVEEEHLWECKQL
GVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCTTPRGTTKVVSIRYYAP
VRQRKGRDTGPGKRKREDEAPILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYL
QPERSCIAESPLWYSVIPMDRSMLESMLNRILAVREIYEELGRPGEEDLD
Target Bioclass
Transcription factor
Subcellular location
Nucleus
Function Plays a role in the regulation of cell morphology and cytoskeletal organization.
Uniprot ID
Q14202
Ensemble ID
ENST00000314425.9
HGNC ID
HGNC:13054

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
A2780 SNV: p.R441W DBIA    Probe Info 
A431 SNV: p.Q1039Ter DBIA    Probe Info 
CALU6 SNV: p.A1280S DBIA    Probe Info 
HCT15 SNV: p.G538V .
HEC1 SNV: p.R740C DBIA    Probe Info 
HEC1B SNV: p.R740C .
HSC3 SNV: p.K489N .
IGROV1 SNV: p.S433N; p.R1289H DBIA    Probe Info 
LNCaP clone FGC Deletion: p.P48LfsTer65 DBIA    Probe Info 
MCC13 SNV: p.G196R; p.E359K DBIA    Probe Info 
MEC1 Deletion: p.G81AfsTer7 DBIA    Probe Info 
MEWO SNV: p.H378Y DBIA    Probe Info 
MFE296 SNV: p.A64S DBIA    Probe Info 
NCIH2286 SNV: p.A145T DBIA    Probe Info 
OE33 SNV: p.D1006N DBIA    Probe Info 
RKO SNV: p.G65S DBIA    Probe Info 
SAOS2 SNV: p.P1009H .
SH4 SNV: p.P1009L DBIA    Probe Info 
SKNSH SNV: p.E468D JN939    Probe Info 
JN942  
JN945  
JN938  
JN940  
JN849  
WM2664 Insertion: p.D58EfsTer4; p.L60AfsTer2; p.D127Ter DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 13 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		12.06  LDD0402  [2]
TH211
 Probe Info  		Y1300(20.00); Y1257(10.74); Y1079(9.48)  LDD0257  [3]
Curcusone 37
 Probe Info  		4.81  LDD0188  [4]
AHL-Pu-1
 Probe Info  		C1073(2.09)  LDD0168  [5]
DBIA
 Probe Info  		C1059(2.08); C1048(2.92); C451(3.09); C715(1.62)  LDD0080  [6]
4-Iodoacetamidophenylacetylene
 Probe Info  		C1106(0.00); C883(0.00); C1326(0.00); C557(0.00)  LDD0038  [7]
IA-alkyne
 Probe Info  		N.A.  LDD0032  [8]
Lodoacetamide azide
 Probe Info  		C835(0.00); C883(0.00); C1106(0.00); C1048(0.00)  LDD0037  [7]
NAIA_4
 Probe Info  		C385(0.00); C1326(0.00)  LDD2226  [9]
IPM
 Probe Info  		C1073(0.00); C484(0.00)  LDD0005  [10]
TFBX
 Probe Info  		C636(0.00); C1048(0.00); C557(0.00); C314(0.00)  LDD0148  [11]
W1
 Probe Info  		N.A.  LDD0236  [12]
NAIA_5
 Probe Info  		C835(0.00); C1106(0.00); C1048(0.00); C883(0.00)  LDD2223  [9]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA HEK-293T C1073(2.09)  LDD0168  [5]
 LDCM0026  4SU-RNA+native RNA HEK-293T C1017(4.26)  LDD0169  [5]
 LDCM0214  AC1 HCT 116 C436(1.36); C619(0.93); C620(0.93); C715(0.89)  LDD0531  [6]
 LDCM0215  AC10 HCT 116 C436(0.94); C619(0.92); C620(1.03); C715(0.40)  LDD0532  [6]
 LDCM0216  AC100 HCT 116 C432(1.39); C436(1.05); C619(1.06); C620(1.06)  LDD0533  [6]
 LDCM0217  AC101 HCT 116 C432(1.04); C436(0.96); C619(1.29); C620(1.29)  LDD0534  [6]
 LDCM0218  AC102 HCT 116 C432(0.94); C436(0.95); C619(1.43); C620(1.43)  LDD0535  [6]
 LDCM0219  AC103 HCT 116 C432(1.32); C436(1.12); C619(1.45); C620(1.45)  LDD0536  [6]
 LDCM0220  AC104 HCT 116 C432(1.15); C436(1.32); C619(1.27); C620(1.27)  LDD0537  [6]
 LDCM0221  AC105 HCT 116 C432(1.04); C436(1.06); C619(1.31); C620(1.31)  LDD0538  [6]
 LDCM0222  AC106 HCT 116 C432(1.37); C436(1.23); C619(1.25); C620(1.25)  LDD0539  [6]
 LDCM0223  AC107 HCT 116 C432(1.04); C436(0.86); C619(1.19); C620(1.19)  LDD0540  [6]
 LDCM0224  AC108 HCT 116 C432(1.17); C436(1.02); C619(1.37); C620(1.37)  LDD0541  [6]
 LDCM0225  AC109 HCT 116 C432(0.76); C436(0.94); C619(1.23); C620(1.23)  LDD0542  [6]
 LDCM0226  AC11 HCT 116 C436(1.30); C619(1.07); C620(1.16); C715(0.32)  LDD0543  [6]
 LDCM0227  AC110 HCT 116 C432(0.70); C436(0.77); C619(1.65); C620(1.65)  LDD0544  [6]
 LDCM0228  AC111 HCT 116 C432(1.02); C436(0.87); C619(1.66); C620(1.66)  LDD0545  [6]
 LDCM0229  AC112 HCT 116 C432(1.00); C436(0.80); C619(1.55); C620(1.55)  LDD0546  [6]
 LDCM0230  AC113 HCT 116 C432(1.01); C436(1.01); C619(0.97); C620(0.97)  LDD0547  [6]
 LDCM0231  AC114 HCT 116 C432(1.15); C436(1.16); C619(1.11); C620(1.11)  LDD0548  [6]
 LDCM0232  AC115 HCT 116 C432(1.49); C436(1.46); C619(1.23); C620(1.23)  LDD0549  [6]
 LDCM0233  AC116 HCT 116 C432(1.28); C436(1.24); C619(1.29); C620(1.29)  LDD0550  [6]
 LDCM0234  AC117 HCT 116 C432(1.09); C436(1.12); C619(1.01); C620(1.01)  LDD0551  [6]
 LDCM0235  AC118 HCT 116 C432(1.14); C436(1.13); C619(1.09); C620(1.09)  LDD0552  [6]
 LDCM0236  AC119 HCT 116 C432(1.23); C436(1.24); C619(1.02); C620(1.02)  LDD0553  [6]
 LDCM0237  AC12 HCT 116 C436(1.06); C619(1.05); C620(1.04); C715(0.49)  LDD0554  [6]
 LDCM0238  AC120 HCT 116 C432(1.35); C436(1.28); C619(1.00); C620(1.00)  LDD0555  [6]
 LDCM0239  AC121 HCT 116 C432(1.07); C436(1.16); C619(1.03); C620(1.03)  LDD0556  [6]
 LDCM0240  AC122 HCT 116 C432(1.24); C436(1.26); C619(1.11); C620(1.11)  LDD0557  [6]
 LDCM0241  AC123 HCT 116 C432(1.10); C436(1.17); C619(0.94); C620(0.94)  LDD0558  [6]
 LDCM0242  AC124 HCT 116 C432(1.00); C436(1.03); C619(1.00); C620(1.00)  LDD0559  [6]
 LDCM0243  AC125 HCT 116 C432(1.13); C436(1.13); C619(1.06); C620(1.06)  LDD0560  [6]
 LDCM0244  AC126 HCT 116 C432(1.39); C436(1.37); C619(1.29); C620(1.29)  LDD0561  [6]
 LDCM0245  AC127 HCT 116 C432(1.21); C436(1.21); C619(1.19); C620(1.19)  LDD0562  [6]
 LDCM0246  AC128 HCT 116 C432(0.61); C436(0.61); C619(1.24); C620(1.24)  LDD0563  [6]
 LDCM0247  AC129 HCT 116 C432(0.57); C436(0.57); C619(0.92); C620(0.89)  LDD0564  [6]
 LDCM0249  AC130 HCT 116 C432(0.68); C436(0.68); C619(1.14); C620(1.15)  LDD0566  [6]
 LDCM0250  AC131 HCT 116 C432(0.62); C436(0.62); C619(0.95); C620(0.92)  LDD0567  [6]
 LDCM0251  AC132 HCT 116 C432(0.71); C436(0.71); C619(0.88); C620(1.02)  LDD0568  [6]
 LDCM0252  AC133 HCT 116 C432(0.68); C436(0.68); C619(1.12); C620(1.06)  LDD0569  [6]
 LDCM0253  AC134 HCT 116 C432(0.70); C436(0.70); C619(1.31); C620(1.18)  LDD0570  [6]
 LDCM0254  AC135 HCT 116 C432(0.70); C436(0.70); C619(1.19); C620(1.19)  LDD0571  [6]
 LDCM0255  AC136 HCT 116 C432(0.71); C436(0.71); C619(1.02); C620(1.05)  LDD0572  [6]
 LDCM0256  AC137 HCT 116 C432(0.69); C436(0.69); C619(1.00); C620(1.08)  LDD0573  [6]
 LDCM0257  AC138 HCT 116 C432(0.82); C436(0.82); C619(1.20); C620(1.27)  LDD0574  [6]
 LDCM0258  AC139 HCT 116 C432(0.85); C436(0.85); C619(1.25); C620(1.27)  LDD0575  [6]
 LDCM0259  AC14 HCT 116 C436(1.19); C619(1.06); C620(1.07); C715(0.87)  LDD0576  [6]
 LDCM0260  AC140 HCT 116 C432(0.96); C436(0.96); C619(1.35); C620(1.28)  LDD0577  [6]
 LDCM0261  AC141 HCT 116 C432(0.87); C436(0.87); C619(1.30); C620(1.27)  LDD0578  [6]
 LDCM0262  AC142 HCT 116 C432(0.77); C436(0.77); C619(1.12); C620(1.16)  LDD0579  [6]
 LDCM0263  AC143 HCT 116 C432(0.95); C436(0.95); C619(1.00); C620(1.00)  LDD0580  [6]
 LDCM0264  AC144 HCT 116 C675(0.82); C1197(0.87); C546(0.91); C715(0.95)  LDD0581  [6]
 LDCM0265  AC145 HCT 116 C675(0.68); C498(0.75); C501(0.75); C1197(0.83)  LDD0582  [6]
 LDCM0266  AC146 HCT 116 C675(0.69); C686(0.88); C570(0.93); C436(0.96)  LDD0583  [6]
 LDCM0267  AC147 HCT 116 C675(0.70); C1197(0.80); C498(0.81); C501(0.81)  LDD0584  [6]
 LDCM0268  AC148 HCT 116 C524(0.93); C527(0.93); C498(0.96); C501(0.96)  LDD0585  [6]
 LDCM0269  AC149 HCT 116 C498(0.87); C501(0.87); C675(0.93); C686(0.95)  LDD0586  [6]
 LDCM0270  AC15 HCT 116 C570(0.96); C574(0.99); C454(1.01); C715(1.05)  LDD0587  [6]
 LDCM0271  AC150 HCT 116 C546(0.75); C675(0.76); C498(0.84); C501(0.84)  LDD0588  [6]
 LDCM0272  AC151 HCT 116 C311(0.76); C314(0.76); C570(0.85); C574(0.96)  LDD0589  [6]
 LDCM0273  AC152 HCT 116 C675(0.83); C686(0.89); C498(0.89); C501(0.89)  LDD0590  [6]
 LDCM0274  AC153 HCT 116 C675(0.60); C498(0.89); C501(0.89); C570(0.91)  LDD0591  [6]
 LDCM0621  AC154 HCT 116 C432(1.08); C436(1.01); C619(0.99); C620(0.99)  LDD2158  [6]
 LDCM0622  AC155 HCT 116 C432(1.18); C436(1.11); C619(1.06); C620(1.06)  LDD2159  [6]
 LDCM0623  AC156 HCT 116 C432(0.94); C436(0.89); C619(0.95); C620(0.95)  LDD2160  [6]
 LDCM0624  AC157 HCT 116 C432(1.02); C436(0.93); C619(0.88); C620(0.88)  LDD2161  [6]
 LDCM0276  AC17 HCT 116 C715(0.68); C1197(0.83); C619(0.86); C454(0.94)  LDD0593  [6]
 LDCM0277  AC18 HCT 116 C1197(0.71); C1326(0.89); C501(0.93); C450(0.96)  LDD0594  [6]
 LDCM0278  AC19 HCT 116 C1197(0.82); C715(0.83); C620(0.87); C675(0.91)  LDD0595  [6]
 LDCM0279  AC2 HCT 116 C715(0.65); C1059(0.78); C524(0.80); C528(0.80)  LDD0596  [6]
 LDCM0280  AC20 HCT 116 C1197(0.78); C702(0.92); C743(0.93); C747(0.93)  LDD0597  [6]
 LDCM0281  AC21 HCT 116 C1197(0.75); C450(0.85); C743(0.97); C747(0.97)  LDD0598  [6]
 LDCM0282  AC22 HCT 116 C501(0.73); C1197(0.75); C706(0.82); C702(0.85)  LDD0599  [6]
 LDCM0283  AC23 HCT 116 C1197(0.77); C743(0.82); C747(0.82); C450(0.83)  LDD0600  [6]
 LDCM0284  AC24 HCT 116 C501(0.81); C1197(0.83); C450(0.87); C706(0.87)  LDD0601  [6]
 LDCM0285  AC25 HCT 116 C450(0.64); C715(0.75); C527(0.91); C1059(0.92)  LDD0602  [6]
 LDCM0286  AC26 HCT 116 C715(0.73); C953(0.78); C968(0.78); C450(0.82)  LDD0603  [6]
 LDCM0287  AC27 HCT 116 C715(0.81); C1197(0.95); C953(0.99); C968(0.99)  LDD0604  [6]
 LDCM0288  AC28 HCT 116 C715(0.63); C450(0.81); C527(0.89); C546(0.98)  LDD0605  [6]
 LDCM0289  AC29 HCT 116 C1197(0.87); C1059(0.88); C450(0.90); C574(1.01)  LDD0606  [6]
 LDCM0290  AC3 HCT 116 C715(0.69); C1059(0.70); C454(0.79); C656(0.80)  LDD0607  [6]
 LDCM0291  AC30 HCT 116 C450(0.91); C953(0.92); C968(0.92); C1197(0.92)  LDD0608  [6]
 LDCM0292  AC31 HCT 116 C715(0.83); C450(0.89); C1197(0.96); C953(0.97)  LDD0609  [6]
 LDCM0293  AC32 HCT 116 C715(0.87); C450(0.95); C546(0.99); C549(0.99)  LDD0610  [6]
 LDCM0294  AC33 HCT 116 C450(0.84); C1197(0.89); C953(1.00); C968(1.00)  LDD0611  [6]
 LDCM0295  AC34 HCT 116 C743(0.89); C747(0.89); C450(0.91); C1197(1.05)  LDD0612  [6]
 LDCM0296  AC35 HCT 116 C715(0.79); C524(0.80); C527(0.80); C528(0.80)  LDD0613  [6]
 LDCM0297  AC36 HCT 116 C686(0.71); C546(0.84); C549(0.84); C656(0.87)  LDD0614  [6]
 LDCM0298  AC37 HCT 116 C686(0.69); C1059(0.81); C451(0.88); C454(0.88)  LDD0615  [6]
 LDCM0299  AC38 HCT 116 C546(0.73); C549(0.73); C557(0.88); C676(0.91)  LDD0616  [6]
 LDCM0300  AC39 HCT 116 C546(0.80); C549(0.80); C676(0.86); C524(0.92)  LDD0617  [6]
 LDCM0301  AC4 HCT 116 C715(0.66); C1059(0.81); C546(0.82); C549(0.82)  LDD0618  [6]
 LDCM0302  AC40 HCT 116 C686(0.89); C546(1.03); C549(1.03); C451(1.05)  LDD0619  [6]
 LDCM0303  AC41 HCT 116 C1059(0.81); C524(0.87); C527(0.87); C528(0.87)  LDD0620  [6]
 LDCM0304  AC42 HCT 116 C686(0.74); C524(0.93); C527(0.93); C528(0.93)  LDD0621  [6]
 LDCM0305  AC43 HCT 116 C1059(0.92); C686(0.94); C633(0.96); C636(0.96)  LDD0622  [6]
 LDCM0306  AC44 HCT 116 C676(0.98); C953(0.99); C968(0.99); C675(1.00)  LDD0623  [6]
 LDCM0307  AC45 HCT 116 C1197(1.02); C546(1.02); C549(1.02); C1059(1.03)  LDD0624  [6]
 LDCM0308  AC46 HCT 116 C454(0.73); C451(0.83); C450(0.84); C570(0.87)  LDD0625  [6]
 LDCM0309  AC47 HCT 116 C570(0.65); C574(0.65); C454(0.70); C450(0.83)  LDD0626  [6]
 LDCM0310  AC48 HCT 116 C570(0.62); C574(0.62); C454(0.69); C1059(0.73)  LDD0627  [6]
 LDCM0311  AC49 HCT 116 C570(0.84); C574(0.84); C498(0.91); C501(1.00)  LDD0628  [6]
 LDCM0312  AC5 HCT 116 C1059(0.76); C715(0.77); C524(0.78); C528(0.78)  LDD0629  [6]
 LDCM0313  AC50 HCT 116 C570(0.68); C574(0.68); C546(0.88); C549(0.88)  LDD0630  [6]
 LDCM0314  AC51 HCT 116 C454(0.67); C451(0.75); C450(0.78); C432(0.80)  LDD0631  [6]
 LDCM0315  AC52 HCT 116 C570(0.75); C574(0.75); C454(0.78); C450(0.86)  LDD0632  [6]
 LDCM0316  AC53 HCT 116 C570(0.82); C574(0.82); C454(0.83); C498(0.86)  LDD0633  [6]
 LDCM0317  AC54 HCT 116 C570(0.69); C574(0.69); C546(0.73); C549(0.73)  LDD0634  [6]
 LDCM0318  AC55 HCT 116 C546(0.56); C549(0.56); C570(0.71); C574(0.71)  LDD0635  [6]
 LDCM0319  AC56 HCT 116 C570(0.77); C574(0.77); C546(0.79); C549(0.79)  LDD0636  [6]
 LDCM0320  AC57 HCT 116 C715(0.87); C498(0.89); C501(0.89); C570(0.89)  LDD0637  [6]
 LDCM0321  AC58 HCT 116 C743(0.84); C747(0.84); C498(0.87); C501(0.87)  LDD0638  [6]
 LDCM0322  AC59 HCT 116 C715(0.87); C743(0.95); C747(0.95); C570(1.01)  LDD0639  [6]
 LDCM0323  AC6 HCT 116 C715(0.94); C1326(1.00); C454(1.01); C1197(1.01)  LDD0640  [6]
 LDCM0324  AC60 HCT 116 C715(0.88); C675(0.91); C676(0.91); C498(1.01)  LDD0641  [6]
 LDCM0325  AC61 HCT 116 C675(0.87); C676(0.87); C498(0.90); C501(0.90)  LDD0642  [6]
 LDCM0326  AC62 HCT 116 C715(0.85); C1048(1.01); C675(1.06); C676(1.06)  LDD0643  [6]
 LDCM0327  AC63 HCT 116 C715(0.80); C335(0.94); C339(0.94); C1048(0.99)  LDD0644  [6]
 LDCM0328  AC64 HCT 116 C715(0.73); C335(1.05); C339(1.05); C570(1.07)  LDD0645  [6]
 LDCM0329  AC65 HCT 116 C335(0.67); C339(0.67); C715(0.82); C675(0.96)  LDD0646  [6]
 LDCM0330  AC66 HCT 116 C335(0.66); C339(0.66); C715(0.76); C432(0.97)  LDD0647  [6]
 LDCM0331  AC67 HCT 116 C335(0.78); C339(0.78); C675(0.99); C676(0.99)  LDD0648  [6]
 LDCM0332  AC68 HCT 116 C702(0.81); C706(0.81); C675(0.88); C546(0.89)  LDD0649  [6]
 LDCM0333  AC69 HCT 116 C1059(0.89); C501(0.90); C702(0.90); C706(0.90)  LDD0650  [6]
 LDCM0334  AC7 HCT 116 C715(0.76); C1059(0.95); C656(0.96); C660(0.96)  LDD0651  [6]
 LDCM0335  AC70 HCT 116 C675(0.56); C686(0.68); C450(0.68); C676(0.79)  LDD0652  [6]
 LDCM0336  AC71 HCT 116 C450(0.75); C528(0.79); C432(0.81); C454(0.81)  LDD0653  [6]
 LDCM0337  AC72 HCT 116 C570(0.79); C450(0.80); C743(0.92); C747(0.92)  LDD0654  [6]
 LDCM0338  AC73 HCT 116 C432(1.19); C715(1.24); C436(1.25); C619(1.34)  LDD0655  [6]
 LDCM0339  AC74 HCT 116 C570(0.84); C498(0.89); C702(0.89); C706(0.89)  LDD0656  [6]
 LDCM0340  AC75 HCT 116 C498(0.95); C570(0.95); C501(0.96); C743(1.04)  LDD0657  [6]
 LDCM0341  AC76 HCT 116 C450(0.80); C570(0.87); C501(0.88); C743(0.89)  LDD0658  [6]
 LDCM0342  AC77 HCT 116 C702(0.88); C706(0.88); C450(0.90); C501(0.95)  LDD0659  [6]
 LDCM0343  AC78 HCT 116 C450(0.80); C702(0.85); C706(0.85); C527(0.86)  LDD0660  [6]
 LDCM0344  AC79 HCT 116 C450(0.69); C454(0.83); C432(0.83); C527(0.87)  LDD0661  [6]
 LDCM0345  AC8 HCT 116 C1326(0.84); C570(0.93); C715(0.97); C702(0.99)  LDD0662  [6]
 LDCM0346  AC80 HCT 116 C570(0.84); C450(0.88); C454(0.88); C546(0.93)  LDD0663  [6]
 LDCM0347  AC81 HCT 116 C450(0.80); C528(0.82); C454(0.84); C570(0.90)  LDD0664  [6]
 LDCM0348  AC82 HCT 116 C450(0.83); C570(0.86); C743(0.95); C747(0.95)  LDD0665  [6]
 LDCM0349  AC83 HCT 116 C557(0.70); C501(0.82); C498(1.03); C450(1.04)  LDD0666  [6]
 LDCM0350  AC84 HCT 116 C557(0.67); C501(0.81); C450(0.93); C498(0.98)  LDD0667  [6]
 LDCM0351  AC85 HCT 116 C557(0.66); C450(0.80); C501(0.85); C498(0.93)  LDD0668  [6]
 LDCM0352  AC86 HCT 116 C557(0.66); C450(0.86); C454(0.90); C570(0.93)  LDD0669  [6]
 LDCM0353  AC87 HCT 116 C557(0.70); C706(0.81); C450(0.82); C656(0.86)  LDD0670  [6]
 LDCM0354  AC88 HCT 116 C557(0.63); C450(0.88); C656(0.91); C660(0.91)  LDD0671  [6]
 LDCM0355  AC89 HCT 116 C557(0.84); C450(0.96); C454(0.99); C311(1.01)  LDD0672  [6]
 LDCM0357  AC90 HCT 116 C715(0.54); C335(0.67); C339(0.67); C557(0.71)  LDD0674  [6]
 LDCM0358  AC91 HCT 116 C557(0.63); C311(0.83); C314(0.83); C1197(1.03)  LDD0675  [6]
 LDCM0359  AC92 HCT 116 C557(0.75); C311(0.76); C314(0.76); C501(0.98)  LDD0676  [6]
 LDCM0360  AC93 HCT 116 C311(0.72); C314(0.72); C557(0.74); C1197(0.85)  LDD0677  [6]
 LDCM0361  AC94 HCT 116 C311(0.67); C314(0.67); C557(0.77); C450(0.81)  LDD0678  [6]
 LDCM0362  AC95 HCT 116 C557(0.67); C311(0.81); C314(0.81); C450(0.82)  LDD0679  [6]
 LDCM0363  AC96 HCT 116 C311(0.72); C314(0.72); C557(0.74); C450(0.87)  LDD0680  [6]
 LDCM0364  AC97 HCT 116 C557(0.79); C311(0.86); C314(0.86); C1197(0.89)  LDD0681  [6]
 LDCM0365  AC98 HCT 116 C1197(0.97); C702(0.97); C706(1.03); C498(1.07)  LDD0682  [6]
 LDCM0366  AC99 HCT 116 C528(0.57); C702(0.75); C335(0.75); C339(0.75)  LDD0683  [6]
 LDCM0248  AKOS034007472 HCT 116 C436(1.17); C619(1.01); C620(1.05); C715(0.61)  LDD0565  [6]
 LDCM0356  AKOS034007680 HCT 116 C715(0.61); C656(0.79); C660(0.79); C619(0.99)  LDD0673  [6]
 LDCM0275  AKOS034007705 HCT 116 C570(0.96); C715(0.97); C574(0.99); C1326(1.01)  LDD0592  [6]
 LDCM0156  Aniline NCI-H1299 N.A.  LDD0405  [2]
 LDCM0020  ARS-1620 HCC44 C335(1.25); C339(1.25); C498(1.30); C501(1.30)  LDD2171  [6]
 LDCM0632  CL-Sc Hep-G2 C835(20.00); C1326(1.53)  LDD2227  [9]
 LDCM0367  CL1 HCT 116 C1197(0.97); C524(0.97); C527(0.97); C528(0.97)  LDD0684  [6]
 LDCM0368  CL10 HCT 116 C715(0.29); C574(0.77); C1197(0.80); C570(0.84)  LDD0685  [6]
 LDCM0369  CL100 HCT 116 C546(0.79); C549(0.79); C715(0.80); C636(0.81)  LDD0686  [6]
 LDCM0370  CL101 HCT 116 C715(0.79); C620(1.02); C619(1.02); C436(1.03)  LDD0687  [6]
 LDCM0371  CL102 HCT 116 C715(0.51); C656(0.70); C660(0.70); C1059(0.87)  LDD0688  [6]
 LDCM0372  CL103 HCT 116 C715(0.39); C1326(0.68); C656(0.84); C660(0.84)  LDD0689  [6]
 LDCM0373  CL104 HCT 116 C1326(0.68); C715(0.84); C451(0.92); C743(0.92)  LDD0690  [6]
 LDCM0374  CL105 HCT 116 C1197(0.79); C715(0.81); C450(0.86); C501(0.90)  LDD0691  [6]
 LDCM0375  CL106 HCT 116 C450(0.79); C1197(0.90); C715(0.90); C743(1.01)  LDD0692  [6]
 LDCM0376  CL107 HCT 116 C1197(0.81); C450(0.86); C715(0.89); C743(0.97)  LDD0693  [6]
 LDCM0377  CL108 HCT 116 C715(0.71); C450(0.87); C1197(0.97); C574(1.02)  LDD0694  [6]
 LDCM0378  CL109 HCT 116 C1197(0.77); C715(0.86); C450(0.87); C574(0.94)  LDD0695  [6]
 LDCM0379  CL11 HCT 116 C715(0.42); C1197(0.93); C450(0.98); C451(0.98)  LDD0696  [6]
 LDCM0380  CL110 HCT 116 C715(0.71); C1197(0.80); C450(0.87); C454(1.02)  LDD0697  [6]
 LDCM0381  CL111 HCT 116 C1197(0.73); C619(0.83); C450(0.85); C743(0.88)  LDD0698  [6]
 LDCM0382  CL112 HCT 116 C450(0.70); C702(0.86); C1059(0.88); C619(0.89)  LDD0699  [6]
 LDCM0383  CL113 HCT 116 C450(0.89); C743(0.94); C747(0.94); C1197(0.95)  LDD0700  [6]
 LDCM0384  CL114 HCT 116 C450(0.80); C574(0.87); C619(0.91); C743(0.93)  LDD0701  [6]
 LDCM0385  CL115 HCT 116 C450(0.77); C743(0.89); C747(0.89); C1197(0.95)  LDD0702  [6]
 LDCM0386  CL116 HCT 116 C527(0.90); C1059(0.92); C574(0.95); C450(0.98)  LDD0703  [6]
 LDCM0387  CL117 HCT 116 C743(1.08); C747(1.08); C686(1.10); C1197(1.14)  LDD0704  [6]
 LDCM0388  CL118 HCT 116 C686(0.83); C715(0.88); C675(0.92); C1059(0.94)  LDD0705  [6]
 LDCM0389  CL119 HCT 116 C715(0.94); C676(0.98); C675(0.98); C686(0.98)  LDD0706  [6]
 LDCM0390  CL12 HCT 116 C715(0.23); C574(0.73); C570(0.77); C1197(0.93)  LDD0707  [6]
 LDCM0391  CL120 HCT 116 C686(0.68); C546(0.79); C549(0.79); C675(0.87)  LDD0708  [6]
 LDCM0392  CL121 HCT 116 C1059(0.75); C676(0.76); C686(0.76); C570(0.78)  LDD0709  [6]
 LDCM0393  CL122 HCT 116 C570(0.75); C574(0.75); C454(0.77); C450(0.83)  LDD0710  [6]
 LDCM0394  CL123 HCT 116 C570(0.75); C574(0.75); C454(0.85); C498(0.93)  LDD0711  [6]
 LDCM0395  CL124 HCT 116 C570(0.64); C574(0.64); C498(0.86); C546(0.91)  LDD0712  [6]
 LDCM0396  CL125 HCT 116 C335(0.71); C339(0.71); C743(0.79); C747(0.79)  LDD0713  [6]
 LDCM0397  CL126 HCT 116 C656(1.07); C660(1.07); C1048(1.14); C675(1.15)  LDD0714  [6]
 LDCM0398  CL127 HCT 116 C715(0.81); C498(0.83); C501(0.83); C432(0.90)  LDD0715  [6]
 LDCM0399  CL128 HCT 116 C743(0.86); C747(0.86); C570(0.86); C574(0.86)  LDD0716  [6]
 LDCM0400  CL13 HCT 116 C570(0.75); C574(0.79); C1197(0.84); C715(0.86)  LDD0717  [6]
 LDCM0401  CL14 HCT 116 C715(0.72); C1197(0.91); C570(0.92); C574(0.92)  LDD0718  [6]
 LDCM0402  CL15 HCT 116 C1197(0.82); C570(0.92); C574(0.93); C450(1.07)  LDD0719  [6]
 LDCM0403  CL16 HCT 116 C715(0.65); C743(0.74); C747(0.74); C675(0.79)  LDD0720  [6]
 LDCM0404  CL17 HCT 116 C498(0.83); C675(0.84); C676(0.84); C501(0.86)  LDD0721  [6]
 LDCM0405  CL18 HCT 116 C715(0.77); C675(0.89); C676(0.89); C1197(0.90)  LDD0722  [6]
 LDCM0406  CL19 HCT 116 C675(0.72); C676(0.72); C498(0.88); C524(0.92)  LDD0723  [6]
 LDCM0407  CL2 HCT 116 C524(0.84); C527(0.84); C528(0.84); C702(0.87)  LDD0724  [6]
 LDCM0408  CL20 HCT 116 C675(0.72); C676(0.72); C1197(0.91); C715(0.95)  LDD0725  [6]
 LDCM0409  CL21 HCT 116 C675(0.74); C676(0.74); C498(0.78); C715(0.80)  LDD0726  [6]
 LDCM0410  CL22 HCT 116 C675(0.75); C676(0.75); C498(0.91); C524(0.92)  LDD0727  [6]
 LDCM0411  CL23 HCT 116 C498(0.93); C1197(0.93); C715(0.96); C1048(0.99)  LDD0728  [6]
 LDCM0412  CL24 HCT 116 C715(0.73); C432(1.68); C436(1.68); C619(1.82)  LDD0729  [6]
 LDCM0413  CL25 HCT 116 C432(1.56); C436(1.56); C619(1.71); C620(1.71)  LDD0730  [6]
 LDCM0414  CL26 HCT 116 C432(1.43); C436(1.43); C619(1.39); C620(1.39)  LDD0731  [6]
 LDCM0415  CL27 HCT 116 C432(1.36); C436(1.36); C619(1.71); C620(1.71)  LDD0732  [6]
 LDCM0416  CL28 HCT 116 C432(1.56); C436(1.56); C619(1.58); C620(1.58)  LDD0733  [6]
 LDCM0417  CL29 HCT 116 C432(1.41); C436(1.41); C619(1.80); C620(1.80)  LDD0734  [6]
 LDCM0418  CL3 HCT 116 C432(1.29); C436(1.27); C619(0.87); C620(0.87)  LDD0735  [6]
 LDCM0419  CL30 HCT 116 C432(1.26); C436(1.26); C619(1.43); C620(1.43)  LDD0736  [6]
 LDCM0420  CL31 HCT 116 C432(1.00); C436(1.00); C619(0.83); C620(0.90)  LDD0737  [6]
 LDCM0421  CL32 HCT 116 C432(1.08); C436(1.08); C619(1.21); C620(1.12)  LDD0738  [6]
 LDCM0422  CL33 HCT 116 C432(1.26); C436(1.26); C619(1.49); C620(1.36)  LDD0739  [6]
 LDCM0423  CL34 HCT 116 C432(1.17); C436(1.17); C619(0.90); C620(1.06)  LDD0740  [6]
 LDCM0424  CL35 HCT 116 C432(1.26); C436(1.26); C619(1.15); C620(1.01)  LDD0741  [6]
 LDCM0425  CL36 HCT 116 C432(1.07); C436(1.07); C619(0.83); C620(0.92)  LDD0742  [6]
 LDCM0426  CL37 HCT 116 C432(1.21); C436(1.21); C619(0.96); C620(1.00)  LDD0743  [6]
 LDCM0428  CL39 HCT 116 C432(1.45); C436(1.45); C619(1.17); C620(1.14)  LDD0745  [6]
 LDCM0429  CL4 HCT 116 C432(1.23); C436(1.27); C619(1.18); C620(1.18)  LDD0746  [6]
 LDCM0430  CL40 HCT 116 C432(1.27); C436(1.27); C619(1.34); C620(1.28)  LDD0747  [6]
 LDCM0431  CL41 HCT 116 C432(1.09); C436(1.09); C619(0.92); C620(0.96)  LDD0748  [6]
 LDCM0432  CL42 HCT 116 C432(1.57); C436(1.57); C619(0.80); C620(0.89)  LDD0749  [6]
 LDCM0433  CL43 HCT 116 C432(1.42); C436(1.42); C619(1.05); C620(1.10)  LDD0750  [6]
 LDCM0434  CL44 HCT 116 C432(1.26); C436(1.26); C619(1.15); C620(1.15)  LDD0751  [6]
 LDCM0435  CL45 HCT 116 C432(1.49); C436(1.49); C619(1.09); C620(1.05)  LDD0752  [6]
 LDCM0436  CL46 HCT 116 C432(0.92); C436(1.01); C619(1.00); C620(1.00)  LDD0753  [6]
 LDCM0437  CL47 HCT 116 C432(0.95); C436(0.97); C619(1.06); C620(1.06)  LDD0754  [6]
 LDCM0438  CL48 HCT 116 C432(0.91); C436(0.92); C619(1.08); C620(1.08)  LDD0755  [6]
 LDCM0439  CL49 HCT 116 C432(0.85); C436(0.91); C619(0.89); C620(0.89)  LDD0756  [6]
 LDCM0440  CL5 HCT 116 C432(1.30); C436(1.36); C619(0.99); C620(0.99)  LDD0757  [6]
 LDCM0441  CL50 HCT 116 C432(0.81); C436(0.91); C619(0.97); C620(0.97)  LDD0758  [6]
 LDCM0442  CL51 HCT 116 C432(0.83); C436(0.94); C619(0.77); C620(0.77)  LDD0759  [6]
 LDCM0443  CL52 HCT 116 C432(0.88); C436(0.94); C619(1.01); C620(1.01)  LDD0760  [6]
 LDCM0444  CL53 HCT 116 C432(0.83); C436(0.84); C619(1.34); C620(1.34)  LDD0761  [6]
 LDCM0445  CL54 HCT 116 C432(1.01); C436(1.06); C619(0.98); C620(0.98)  LDD0762  [6]
 LDCM0446  CL55 HCT 116 C432(0.95); C436(0.94); C619(0.97); C620(0.97)  LDD0763  [6]
 LDCM0447  CL56 HCT 116 C432(1.06); C436(1.07); C619(1.03); C620(1.03)  LDD0764  [6]
 LDCM0448  CL57 HCT 116 C432(0.85); C436(0.92); C619(1.13); C620(1.13)  LDD0765  [6]
 LDCM0449  CL58 HCT 116 C432(0.92); C436(0.96); C619(1.12); C620(1.12)  LDD0766  [6]
 LDCM0450  CL59 HCT 116 C432(0.96); C436(0.97); C619(1.00); C620(1.00)  LDD0767  [6]
 LDCM0451  CL6 HCT 116 C432(1.21); C436(1.24); C619(1.03); C620(1.03)  LDD0768  [6]
 LDCM0452  CL60 HCT 116 C432(0.91); C436(0.97); C619(1.01); C620(1.01)  LDD0769  [6]
 LDCM0453  CL61 HCT 116 C432(0.98); C436(0.93); C619(0.82); C620(0.82)  LDD0770  [6]
 LDCM0454  CL62 HCT 116 C432(0.99); C436(0.95); C619(0.84); C620(0.84)  LDD0771  [6]
 LDCM0455  CL63 HCT 116 C432(1.08); C436(1.03); C619(0.88); C620(0.88)  LDD0772  [6]
 LDCM0456  CL64 HCT 116 C432(1.25); C436(1.18); C619(0.92); C620(0.92)  LDD0773  [6]
 LDCM0457  CL65 HCT 116 C432(0.99); C436(0.95); C619(0.85); C620(0.85)  LDD0774  [6]
 LDCM0458  CL66 HCT 116 C432(1.43); C436(1.38); C619(1.08); C620(1.08)  LDD0775  [6]
 LDCM0459  CL67 HCT 116 C432(1.43); C436(1.32); C619(0.97); C620(0.97)  LDD0776  [6]
 LDCM0460  CL68 HCT 116 C432(1.18); C436(1.12); C619(1.23); C620(1.23)  LDD0777  [6]
 LDCM0461  CL69 HCT 116 C432(1.11); C436(1.04); C619(1.22); C620(1.22)  LDD0778  [6]
 LDCM0462  CL7 HCT 116 C432(1.42); C436(1.52); C619(1.16); C620(1.16)  LDD0779  [6]
 LDCM0463  CL70 HCT 116 C432(1.14); C436(1.09); C619(0.92); C620(0.92)  LDD0780  [6]
 LDCM0464  CL71 HCT 116 C432(1.13); C436(1.08); C619(0.84); C620(0.84)  LDD0781  [6]
 LDCM0465  CL72 HCT 116 C432(1.09); C436(1.01); C619(0.89); C620(0.89)  LDD0782  [6]
 LDCM0466  CL73 HCT 116 C432(1.06); C436(1.03); C619(0.95); C620(0.95)  LDD0783  [6]
 LDCM0467  CL74 HCT 116 C432(1.13); C436(1.06); C619(1.02); C620(1.02)  LDD0784  [6]
 LDCM0469  CL76 HCT 116 C432(0.93); C436(0.93); C619(1.35); C620(1.35)  LDD0786  [6]
 LDCM0470  CL77 HCT 116 C432(0.82); C436(0.82); C619(0.98); C620(0.98)  LDD0787  [6]
 LDCM0471  CL78 HCT 116 C432(1.01); C436(1.01); C619(1.25); C620(1.25)  LDD0788  [6]
 LDCM0472  CL79 HCT 116 C432(0.95); C436(0.95); C619(1.31); C620(1.31)  LDD0789  [6]
 LDCM0473  CL8 HCT 116 C432(1.74); C436(2.18); C619(1.43); C620(1.43)  LDD0790  [6]
 LDCM0474  CL80 HCT 116 C432(0.91); C436(0.91); C619(1.05); C620(1.05)  LDD0791  [6]
 LDCM0475  CL81 HCT 116 C432(0.84); C436(0.84); C619(0.99); C620(0.99)  LDD0792  [6]
 LDCM0476  CL82 HCT 116 C432(0.79); C436(0.79); C619(1.35); C620(1.35)  LDD0793  [6]
 LDCM0477  CL83 HCT 116 C432(1.04); C436(1.04); C619(1.30); C620(1.30)  LDD0794  [6]
 LDCM0478  CL84 HCT 116 C432(1.03); C436(1.03); C619(1.39); C620(1.39)  LDD0795  [6]
 LDCM0479  CL85 HCT 116 C432(1.20); C436(1.20); C619(1.25); C620(1.25)  LDD0796  [6]
 LDCM0480  CL86 HCT 116 C432(1.08); C436(1.08); C619(1.17); C620(1.17)  LDD0797  [6]
 LDCM0481  CL87 HCT 116 C432(1.08); C436(1.08); C619(1.15); C620(1.15)  LDD0798  [6]
 LDCM0482  CL88 HCT 116 C432(1.03); C436(1.03); C619(1.84); C620(1.84)  LDD0799  [6]
 LDCM0483  CL89 HCT 116 C432(1.04); C436(1.04); C619(2.13); C620(2.13)  LDD0800  [6]
 LDCM0484  CL9 HCT 116 C432(1.25); C436(1.33); C619(1.06); C620(1.06)  LDD0801  [6]
 LDCM0485  CL90 HCT 116 C432(1.09); C436(1.09); C619(2.02); C620(2.02)  LDD0802  [6]
 LDCM0486  CL91 HCT 116 C436(1.36); C619(1.15); C620(1.15); C715(1.06)  LDD0803  [6]
 LDCM0487  CL92 HCT 116 C436(1.13); C619(0.91); C620(0.91); C715(1.05)  LDD0804  [6]
 LDCM0488  CL93 HCT 116 C436(1.20); C619(0.97); C620(0.97); C715(0.56)  LDD0805  [6]
 LDCM0489  CL94 HCT 116 C436(1.65); C619(1.17); C620(1.17); C715(0.71)  LDD0806  [6]
 LDCM0490  CL95 HCT 116 C436(1.47); C619(1.32); C620(1.32); C715(0.70)  LDD0807  [6]
 LDCM0491  CL96 HCT 116 C436(1.57); C619(1.14); C620(1.14); C715(0.82)  LDD0808  [6]
 LDCM0492  CL97 HCT 116 C436(1.34); C619(1.14); C620(1.14); C715(0.83)  LDD0809  [6]
 LDCM0493  CL98 HCT 116 C436(1.07); C619(0.98); C620(0.98); C715(0.73)  LDD0810  [6]
 LDCM0494  CL99 HCT 116 C436(1.22); C619(1.03); C620(1.03); C715(0.76)  LDD0811  [6]
 LDCM0033  Curcusone1d MCF-7 4.81  LDD0188  [4]
 LDCM0495  E2913 HEK-293T C557(0.98); C1197(0.95); C1326(0.79); C1106(1.02)  LDD1698  [13]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C633(1.85); C636(1.14); C480(1.01); C484(0.98)  LDD1702  [14]
 LDCM0468  Fragment33 HCT 116 C432(1.26); C436(1.20); C619(1.12); C620(1.12)  LDD0785  [6]
 LDCM0427  Fragment51 HCT 116 C432(1.96); C436(1.96); C619(0.93); C620(0.86)  LDD0744  [6]
 LDCM0022  KB02 HCT 116 C1059(2.08); C1048(2.92); C451(3.09); C715(1.62)  LDD0080  [6]
 LDCM0023  KB03 HCT 116 C1059(2.11); C1048(2.68); C451(3.67); C715(1.10)  LDD0081  [6]
 LDCM0024  KB05 HCT 116 C1059(3.40); C1048(3.28); C451(2.96); C715(2.16)  LDD0082  [6]
 LDCM0021  THZ1 HCT 116 C335(1.25); C339(1.25); C498(1.30); C501(1.30)  LDD2173  [6]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Histone acetyltransferase KAT5 (KAT5) MYST (SAS/MOZ) family Q92993
Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
14-3-3 protein gamma (YWHAG) 14-3-3 family P61981

References

1 Labeling Preferences of Diazirines with Protein Biomolecules. J Am Chem Soc. 2021 May 5;143(17):6691-6700. doi: 10.1021/jacs.1c02509. Epub 2021 Apr 20.
Mass spectrometry data entry: PXD025140
2 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
3 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
4 Total Synthesis and Target Identification of the Curcusone Diterpenes. J Am Chem Soc. 2021 Mar 24;143(11):4379-4386. doi: 10.1021/jacs.1c00557. Epub 2021 Mar 11.
5 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
6 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
7 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
8 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
9 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
10 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
11 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
12 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
13 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
14 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761