Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name JN939;JN942;JN945;JN938;JN940;JN849  Probe Info 
Probe concentration all probe:10 uM
Criteria Qualitation: Labeling site identification
In Vivo Experiment Model Model Type Living cell
Derived Tissue Adrenal
Disease Model Neuroblastoma [ICD-11:2D50]
Model Name Human neuroblastoma cells (SK-N-SH)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 28 Protein Related to This Bioclass
Target ID Target Name Binding Sites
 LDTP12551  1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (AGPAT3) A194
 LDTP04876  Actin, cytoplasmic 1 (ACTB) V96
 LDTP04876  Actin, cytoplasmic 1 (ACTB) A97
 LDTP04876  Actin, cytoplasmic 1 (ACTB) E100
 LDTP07830  E3 ubiquitin-protein ligase UBR3 (UBR3) E1730
 LDTP07830  E3 ubiquitin-protein ligase UBR3 (UBR3) G1732
 LDTP03849  Electron transfer flavoprotein subunit beta (ETFB) G33
 LDTP03849  Electron transfer flavoprotein subunit beta (ETFB) V34
 LDTP02534  Endoplasmic reticulum chaperone BiP (HSPA5) V465
 LDTP02534  Endoplasmic reticulum chaperone BiP (HSPA5) Y466
 LDTP02534  Endoplasmic reticulum chaperone BiP (HSPA5) E467
 LDTP09396  Minor histocompatibility antigen H13 (HM13) N62
 LDTP09396  Minor histocompatibility antigen H13 (HM13) A63
 LDTP09396  Minor histocompatibility antigen H13 (HM13) S64
 LDTP09396  Minor histocompatibility antigen H13 (HM13) D65
 LDTP03765  Myosin-10 (MYH10) V774
 LDTP03765  Myosin-10 (MYH10) L775
 LDTP03912  Trifunctional enzyme subunit alpha, mitochondrial (HADHA) A338
 LDTP03912  Trifunctional enzyme subunit alpha, mitochondrial (HADHA) L339
 LDTP03912  Trifunctional enzyme subunit alpha, mitochondrial (HADHA) G341
 LDTP03912  Trifunctional enzyme subunit alpha, mitochondrial (HADHA) L342
 LDTP03912  Trifunctional enzyme subunit alpha, mitochondrial (HADHA) L348
 LDTP03912  Trifunctional enzyme subunit alpha, mitochondrial (HADHA) K350
 LDTP03912  Trifunctional enzyme subunit alpha, mitochondrial (HADHA) M340
 LDTP01368  Triple functional domain protein (TRIO) Q1815
 LDTP13720  Ubiquitin carboxyl-terminal hydrolase 24 (USP24) A811
 LDTP12099  Ubiquitin carboxyl-terminal hydrolase 42 (USP42) E1248
 LDTP12099  Ubiquitin carboxyl-terminal hydrolase 42 (USP42) D1249
Transporter and channel
Click to Show/Hide to Show 6 Protein Related to This Bioclass
Target ID Target Name Binding Sites
 LDTP06034  Lysosome membrane protein 2 (SCARB2) V140
 LDTP06034  Lysosome membrane protein 2 (SCARB2) I144
 LDTP06034  Lysosome membrane protein 2 (SCARB2) H150
 LDTP13174  Mitochondrial dicarboxylate carrier (SLC25A10) Q94
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) V164
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) V171
Transcription factor
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Sites
 LDTP06081  Zinc finger MYM-type protein 3 (ZMYM3) T310
 LDTP06081  Zinc finger MYM-type protein 3 (ZMYM3) C311
 LDTP06081  Zinc finger MYM-type protein 3 (ZMYM3) C314
Other
Click to Show/Hide to Show 54 Protein Related to This Bioclass
Target ID Target Name Binding Sites
 LDTP02913  Desmin (DES) E387
 LDTP02913  Desmin (DES) Y388
 LDTP02913  Desmin (DES) Q389
 LDTP02913  Desmin (DES) K395
 LDTP02913  Desmin (DES) N393
 LDTP02913  Desmin (DES) V394
 LDTP13014  Dynein axonemal heavy chain 2 (DNAH2) D1485
 LDTP08448  ELKS/Rab6-interacting/CAST family member 1 (ERC1) Q470
 LDTP08448  ELKS/Rab6-interacting/CAST family member 1 (ERC1) Q473
 LDTP08448  ELKS/Rab6-interacting/CAST family member 1 (ERC1) E474
 LDTP08448  ELKS/Rab6-interacting/CAST family member 1 (ERC1) L475
 LDTP08448  ELKS/Rab6-interacting/CAST family member 1 (ERC1) R477
 LDTP02734  Endoplasmin (HSP90B1) A664
 LDTP02734  Endoplasmin (HSP90B1) L494
 LDTP02734  Endoplasmin (HSP90B1) G495
 LDTP02710  Glial fibrillary acidic protein (GFAP) G301
 LDTP02710  Glial fibrillary acidic protein (GFAP) T302
 LDTP11000  Histone H2B type 1-M (H2BC14) E114
 LDTP05004  Histone H4 (H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16) V71
 LDTP05004  Histone H4 (H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16) D69
 LDTP02164  Nucleophosmin (NPM1) S88
 LDTP02164  Nucleophosmin (NPM1) Q84
 LDTP02164  Nucleophosmin (NPM1) G91
 LDTP02164  Nucleophosmin (NPM1) V33
 LDTP04684  Nucleosome assembly protein 1-like 1 (NAP1L1) E97
 LDTP04684  Nucleosome assembly protein 1-like 1 (NAP1L1) F95
 LDTP14342  POTE ankyrin domain family member F (POTEF) A722
 LDTP14342  POTE ankyrin domain family member F (POTEF) D724
 LDTP10924  Prohibitin-2 (PHB2) F41
 LDTP10924  Prohibitin-2 (PHB2) S39
 LDTP12412  Reticulon-4 (RTN4) L1168
 LDTP12412  Reticulon-4 (RTN4) Y1091
 LDTP12412  Reticulon-4 (RTN4) N1093
 LDTP12412  Reticulon-4 (RTN4) V1099
 LDTP12412  Reticulon-4 (RTN4) N1100
 LDTP12412  Reticulon-4 (RTN4) C1101
 LDTP12412  Reticulon-4 (RTN4) T1102
 LDTP12412  Reticulon-4 (RTN4) I1103
 LDTP12412  Reticulon-4 (RTN4) L1096
 LDTP08738  Tetratricopeptide repeat protein 5 (TTC5) D45
 LDTP02297  Vimentin (VIM) E198
 LDTP02297  Vimentin (VIM) E346
 LDTP02297  Vimentin (VIM) V353
 LDTP02297  Vimentin (VIM) I130
 LDTP02297  Vimentin (VIM) L132
 LDTP02297  Vimentin (VIM) F233
 LDTP02297  Vimentin (VIM) L234
 LDTP02297  Vimentin (VIM) I369
 LDTP02297  Vimentin (VIM) L365
 LDTP02297  Vimentin (VIM) D367
 LDTP02297  Vimentin (VIM) E368
 LDTP02297  Vimentin (VIM) K373
 LDTP02297  Vimentin (VIM) N283
 LDTP02297  Vimentin (VIM) E286

References

1 Labeling Preferences of Diazirines with Protein Biomolecules. J Am Chem Soc. 2021 May 5;143(17):6691-6700. doi: 10.1021/jacs.1c02509. Epub 2021 Apr 20.
Mass spectrometry data entry: PXD025140