General Information of Experiment

Probe Name C006  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 15 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP02175  Epoxide hydrolase 1 (EPHX1) 15.0
 LDTP08265  N-alpha-acetyltransferase 40 (NAA40) 10.1
 LDTP12628  Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) 9.9
 LDTP06227  Prostaglandin reductase 1 (PTGR1) 9.7
 LDTP15422  Prostaglandin reductase 3 (PTGR3) 8.7
 LDTP02837  Beta-galactosidase (GLB1) 8.5
 LDTP08565  E3 ubiquitin-protein ligase UBR2 (UBR2) 6.4
 LDTP12013  dCTP pyrophosphatase 1 (DCTPP1) 6.3
 LDTP04183  Lanosterol synthase (LSS) 6.3
 LDTP04689  Adenosine kinase (ADK) 6.2
 LDTP01687  Apoptosis-inducing factor 1, mitochondrial (AIFM1) 6.1
 LDTP04712  Puromycin-sensitive aminopeptidase (NPEPPS) 5.9
 LDTP09799  DCN1-like protein 4 (DCUN1D4) 5.3
 LDTP06375  Delta(24)-sterol reductase (DHCR24) 5.1
 LDTP04285  Proteasome subunit beta type-2 (PSMB2) 5.0
Transporter and channel
Click to Show/Hide to Show 10 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP11095  Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) 26.4
 LDTP10958  Sigma non-opioid intracellular receptor 1 (SIGMAR1) 17.8
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 8.2
 LDTP00821  Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) 6.5
 LDTP18153  Major facilitator superfamily domain-containing protein 3 (MFSD3) 6.3
 LDTP07885  Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) 5.7
 LDTP11162  Solute carrier family 25 member 33 (SLC25A33) 5.4
 LDTP02724  Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) 5.4
 LDTP05384  Mitochondrial 2-oxoglutarate/malate carrier protein (SLC25A11) 5.2
 LDTP15948  Transmembrane protein 126A (TMEM126A) 5.2
Other
Click to Show/Hide to Show 3 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP13755  Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) 8.4
 LDTP00105  Protein unc-119 homolog B (UNC119B) 6.3
 LDTP15623  Neuferricin (CYB5D2) 5.4

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587