Details of the Target

General Information of Target

Target ID LDTP11115
Target Name Leucine zipper putative tumor suppressor 2 (LZTS2)
Gene Name LZTS2
Gene ID 84445
Synonyms
KIAA1813; LAPSER1; Leucine zipper putative tumor suppressor 2; hLZTS2; Protein LAPSER1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MALPSRILLWKLVLLQSSAVLLHSGSSVPAAAGSSVVSESAVSWEAGARAVLRCQSPRMV
WTQDRLHDRQRVLHWDLRGPGGGPARRLLDLYSAGEQRVYEARDRGRLELSASAFDDGNF
SLLIRAVEETDAGLYTCNLHHHYCHLYESLAVRLEVTDGPPATPAYWDGEKEVLAVARGA
PALLTCVNRGHVWTDRHVEEAQQVVHWDRQPPGVPHDRADRLLDLYASGERRAYGPLFLR
DRVAVGADAFERGDFSLRIEPLEVADEGTYSCHLHHHYCGLHERRVFHLTVAEPHAEPPP
RGSPGNGSSHSGAPGPDPTLARGHNVINVIVPESRAHFFQQLGYVLATLLLFILLLVTVL
LAARRRRGGYEYSDQKSGKSKGKDVNLAEFAVAAGDQMLYRSEDIQLDYKNNILKERAEL
AHSPLPAKYIDLDKGFRKENCK
Target Bioclass
Other
Family
LZTS2 family
Subcellular location
Cytoplasm
Function
Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. {|HAMAP-Rule:MF_03026}.
Uniprot ID
Q9BRK4
Ensemble ID
ENST00000370220.1
HGNC ID
HGNC:29381

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 7 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
IPM
 Probe Info  		N.A.  LDD0241  [1]
AHL-Pu-1
 Probe Info  		C376(4.03)  LDD0168  [2]
HPAP
 Probe Info  		3.46  LDD0062  [3]
DBIA
 Probe Info  		C212(0.84); C376(0.74)  LDD0531  [4]
1d-yne
 Probe Info  		N.A.  LDD0357  [5]
AOyne
 Probe Info  		12.70  LDD0443  [6]
NAIA_5
 Probe Info  		C376(0.00); C509(0.00)  LDD2223  [7]
PAL-AfBPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C266
 Probe Info  		8.57  LDD1937  [8]
C269
 Probe Info  		7.16  LDD1939  [8]
C270
 Probe Info  		6.19  LDD1940  [8]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA HEK-293T C376(4.03)  LDD0168  [2]
 LDCM0026  4SU-RNA+native RNA HEK-293T C376(2.48)  LDD0169  [2]
 LDCM0214  AC1 HCT 116 C212(0.84); C376(0.74)  LDD0531  [4]
 LDCM0215  AC10 HCT 116 C212(0.76)  LDD0532  [4]
 LDCM0216  AC100 HCT 116 C355(0.84)  LDD0533  [4]
 LDCM0217  AC101 HCT 116 C355(1.02)  LDD0534  [4]
 LDCM0218  AC102 HCT 116 C355(1.07)  LDD0535  [4]
 LDCM0219  AC103 HCT 116 C355(1.38)  LDD0536  [4]
 LDCM0220  AC104 HCT 116 C355(1.09)  LDD0537  [4]
 LDCM0221  AC105 HCT 116 C355(1.24)  LDD0538  [4]
 LDCM0222  AC106 HCT 116 C355(1.23)  LDD0539  [4]
 LDCM0223  AC107 HCT 116 C355(1.04)  LDD0540  [4]
 LDCM0224  AC108 HCT 116 C355(0.97)  LDD0541  [4]
 LDCM0225  AC109 HCT 116 C355(0.96)  LDD0542  [4]
 LDCM0226  AC11 HCT 116 C212(0.92)  LDD0543  [4]
 LDCM0227  AC110 HCT 116 C355(1.09)  LDD0544  [4]
 LDCM0228  AC111 HCT 116 C355(1.22)  LDD0545  [4]
 LDCM0229  AC112 HCT 116 C355(1.47)  LDD0546  [4]
 LDCM0230  AC113 HCT 116 C355(1.13); C376(0.76)  LDD0547  [4]
 LDCM0231  AC114 HCT 116 C355(1.08); C376(0.82)  LDD0548  [4]
 LDCM0232  AC115 HCT 116 C355(1.04); C376(0.84)  LDD0549  [4]
 LDCM0233  AC116 HCT 116 C355(1.00); C376(0.81)  LDD0550  [4]
 LDCM0234  AC117 HCT 116 C355(1.07); C376(1.02)  LDD0551  [4]
 LDCM0235  AC118 HCT 116 C355(0.98); C376(0.94)  LDD0552  [4]
 LDCM0236  AC119 HCT 116 C355(1.05); C376(0.92)  LDD0553  [4]
 LDCM0237  AC12 HCT 116 C212(0.70)  LDD0554  [4]
 LDCM0238  AC120 HCT 116 C355(0.90); C376(0.75)  LDD0555  [4]
 LDCM0239  AC121 HCT 116 C355(0.98); C376(1.13)  LDD0556  [4]
 LDCM0240  AC122 HCT 116 C355(1.01); C376(0.93)  LDD0557  [4]
 LDCM0241  AC123 HCT 116 C355(1.24); C376(1.43)  LDD0558  [4]
 LDCM0242  AC124 HCT 116 C355(0.93); C376(1.02)  LDD0559  [4]
 LDCM0243  AC125 HCT 116 C355(0.97); C376(0.70)  LDD0560  [4]
 LDCM0244  AC126 HCT 116 C355(1.16); C376(0.94)  LDD0561  [4]
 LDCM0245  AC127 HCT 116 C355(0.93); C376(0.82)  LDD0562  [4]
 LDCM0246  AC128 HCT 116 C212(1.08)  LDD0563  [4]
 LDCM0247  AC129 HCT 116 C212(1.31)  LDD0564  [4]
 LDCM0249  AC130 HCT 116 C212(1.32)  LDD0566  [4]
 LDCM0250  AC131 HCT 116 C212(1.20)  LDD0567  [4]
 LDCM0251  AC132 HCT 116 C212(1.23)  LDD0568  [4]
 LDCM0252  AC133 HCT 116 C212(1.05)  LDD0569  [4]
 LDCM0253  AC134 HCT 116 C212(1.22)  LDD0570  [4]
 LDCM0254  AC135 HCT 116 C212(0.88)  LDD0571  [4]
 LDCM0255  AC136 HCT 116 C212(1.17)  LDD0572  [4]
 LDCM0256  AC137 HCT 116 C212(1.05)  LDD0573  [4]
 LDCM0257  AC138 HCT 116 C212(1.51)  LDD0574  [4]
 LDCM0258  AC139 HCT 116 C212(1.41)  LDD0575  [4]
 LDCM0259  AC14 HCT 116 C212(0.89)  LDD0576  [4]
 LDCM0260  AC140 HCT 116 C212(1.10)  LDD0577  [4]
 LDCM0261  AC141 HCT 116 C212(1.04)  LDD0578  [4]
 LDCM0262  AC142 HCT 116 C212(1.07)  LDD0579  [4]
 LDCM0263  AC143 HEK-293T C376(0.95)  LDD0861  [4]
 LDCM0264  AC144 HEK-293T C376(1.15)  LDD0862  [4]
 LDCM0265  AC145 HEK-293T C376(0.93)  LDD0863  [4]
 LDCM0266  AC146 HEK-293T C376(1.62)  LDD0864  [4]
 LDCM0267  AC147 HEK-293T C376(1.74)  LDD0865  [4]
 LDCM0268  AC148 HEK-293T C376(1.05)  LDD0866  [4]
 LDCM0269  AC149 HEK-293T C376(1.14)  LDD0867  [4]
 LDCM0270  AC15 HCT 116 C212(0.63)  LDD0587  [4]
 LDCM0271  AC150 HEK-293T C376(1.18)  LDD0869  [4]
 LDCM0272  AC151 HEK-293T C376(1.56)  LDD0870  [4]
 LDCM0273  AC152 HEK-293T C376(1.10)  LDD0871  [4]
 LDCM0274  AC153 HEK-293T C376(2.00)  LDD0872  [4]
 LDCM0621  AC154 HEK-293T C376(1.00)  LDD2162  [4]
 LDCM0622  AC155 HEK-293T C376(0.94)  LDD2163  [4]
 LDCM0623  AC156 HEK-293T C376(2.11)  LDD2164  [4]
 LDCM0624  AC157 HEK-293T C376(2.65)  LDD2165  [4]
 LDCM0276  AC17 HCT 116 C355(1.03); C376(1.19)  LDD0593  [4]
 LDCM0277  AC18 HCT 116 C355(0.81); C376(1.58)  LDD0594  [4]
 LDCM0278  AC19 HCT 116 C355(1.01); C376(1.27)  LDD0595  [4]
 LDCM0279  AC2 HCT 116 C376(0.82); C212(1.01)  LDD0596  [4]
 LDCM0280  AC20 HCT 116 C376(0.82); C355(1.12)  LDD0597  [4]
 LDCM0281  AC21 HCT 116 C355(0.88); C376(1.10)  LDD0598  [4]
 LDCM0282  AC22 HCT 116 C376(0.91); C355(1.04)  LDD0599  [4]
 LDCM0283  AC23 HCT 116 C355(0.82); C376(0.88)  LDD0600  [4]
 LDCM0284  AC24 HCT 116 C355(1.08); C376(1.36)  LDD0601  [4]
 LDCM0285  AC25 HEK-293T C38(1.04)  LDD1524  [9]
 LDCM0286  AC26 HEK-293T C38(0.87)  LDD1525  [9]
 LDCM0287  AC27 HEK-293T C38(1.06); C212(0.75)  LDD1526  [9]
 LDCM0288  AC28 HEK-293T C38(0.83); C212(0.48)  LDD1527  [9]
 LDCM0289  AC29 HEK-293T C38(1.08)  LDD1528  [9]
 LDCM0290  AC3 HCT 116 C376(0.68); C212(0.82)  LDD0607  [4]
 LDCM0291  AC30 HEK-293T C38(1.06); C509(0.95)  LDD1530  [9]
 LDCM0293  AC32 HEK-293T C38(0.92)  LDD1532  [9]
 LDCM0294  AC33 HEK-293T C38(1.12)  LDD1533  [9]
 LDCM0295  AC34 HEK-293T C38(1.11)  LDD1534  [9]
 LDCM0296  AC35 HCT 116 C376(1.13)  LDD0613  [4]
 LDCM0297  AC36 HCT 116 C376(1.07)  LDD0614  [4]
 LDCM0298  AC37 HCT 116 C376(0.99)  LDD0615  [4]
 LDCM0299  AC38 HCT 116 C376(1.11)  LDD0616  [4]
 LDCM0300  AC39 HCT 116 C376(1.22)  LDD0617  [4]
 LDCM0301  AC4 HCT 116 C376(0.76); C212(0.86)  LDD0618  [4]
 LDCM0302  AC40 HCT 116 C376(1.26)  LDD0619  [4]
 LDCM0303  AC41 HCT 116 C376(1.28)  LDD0620  [4]
 LDCM0304  AC42 HCT 116 C376(1.34)  LDD0621  [4]
 LDCM0305  AC43 HCT 116 C376(1.15)  LDD0622  [4]
 LDCM0306  AC44 HCT 116 C376(1.18)  LDD0623  [4]
 LDCM0307  AC45 HCT 116 C376(1.33)  LDD0624  [4]
 LDCM0308  AC46 HCT 116 C376(1.05)  LDD0625  [4]
 LDCM0309  AC47 HCT 116 C376(1.49)  LDD0626  [4]
 LDCM0310  AC48 HCT 116 C376(2.02)  LDD0627  [4]
 LDCM0311  AC49 HCT 116 C376(2.46)  LDD0628  [4]
 LDCM0312  AC5 HCT 116 C212(0.71); C376(0.99)  LDD0629  [4]
 LDCM0313  AC50 HCT 116 C376(1.58)  LDD0630  [4]
 LDCM0314  AC51 HCT 116 C376(0.95)  LDD0631  [4]
 LDCM0315  AC52 HCT 116 C376(1.21)  LDD0632  [4]
 LDCM0316  AC53 HCT 116 C376(1.84)  LDD0633  [4]
 LDCM0317  AC54 HCT 116 C376(1.78)  LDD0634  [4]
 LDCM0318  AC55 HCT 116 C376(1.83)  LDD0635  [4]
 LDCM0319  AC56 HCT 116 C376(3.54)  LDD0636  [4]
 LDCM0320  AC57 HCT 116 C376(1.50)  LDD0637  [4]
 LDCM0321  AC58 HCT 116 C376(1.35)  LDD0638  [4]
 LDCM0322  AC59 HCT 116 C376(1.47)  LDD0639  [4]
 LDCM0323  AC6 HCT 116 C212(0.93)  LDD0640  [4]
 LDCM0324  AC60 HCT 116 C376(1.51)  LDD0641  [4]
 LDCM0325  AC61 HCT 116 C376(1.17)  LDD0642  [4]
 LDCM0326  AC62 HCT 116 C376(1.32)  LDD0643  [4]
 LDCM0327  AC63 HCT 116 C376(1.49)  LDD0644  [4]
 LDCM0328  AC64 HCT 116 C376(1.39)  LDD0645  [4]
 LDCM0329  AC65 HCT 116 C376(1.33)  LDD0646  [4]
 LDCM0330  AC66 HCT 116 C376(1.54)  LDD0647  [4]
 LDCM0331  AC67 HCT 116 C376(1.58)  LDD0648  [4]
 LDCM0332  AC68 HCT 116 C355(0.75); C376(0.93)  LDD0649  [4]
 LDCM0333  AC69 HCT 116 C355(0.69); C376(0.88)  LDD0650  [4]
 LDCM0334  AC7 HCT 116 C212(0.53)  LDD0651  [4]
 LDCM0335  AC70 HCT 116 C376(0.93); C355(1.00)  LDD0652  [4]
 LDCM0336  AC71 HCT 116 C376(0.91); C355(0.94)  LDD0653  [4]
 LDCM0337  AC72 HCT 116 C355(0.90); C376(1.11)  LDD0654  [4]
 LDCM0338  AC73 HCT 116 C355(1.16); C376(1.32)  LDD0655  [4]
 LDCM0339  AC74 HCT 116 C355(1.06); C376(1.30)  LDD0656  [4]
 LDCM0340  AC75 HCT 116 C355(1.22); C376(1.56)  LDD0657  [4]
 LDCM0341  AC76 HCT 116 C355(0.88); C376(1.22)  LDD0658  [4]
 LDCM0342  AC77 HCT 116 C355(0.86); C376(0.97)  LDD0659  [4]
 LDCM0343  AC78 HCT 116 C376(1.05); C355(1.22)  LDD0660  [4]
 LDCM0344  AC79 HCT 116 C355(1.01); C376(1.07)  LDD0661  [4]
 LDCM0345  AC8 HCT 116 C212(0.89)  LDD0662  [4]
 LDCM0346  AC80 HCT 116 C376(1.11); C355(1.31)  LDD0663  [4]
 LDCM0347  AC81 HCT 116 C355(0.87); C376(1.02)  LDD0664  [4]
 LDCM0348  AC82 HCT 116 C355(1.28); C376(1.61)  LDD0665  [4]
 LDCM0349  AC83 HCT 116 C355(0.87); C212(1.79); C376(1.86)  LDD0666  [4]
 LDCM0350  AC84 HCT 116 C355(0.90); C212(1.68); C376(1.80)  LDD0667  [4]
 LDCM0351  AC85 HCT 116 C355(0.95); C376(1.35); C212(1.59)  LDD0668  [4]
 LDCM0352  AC86 HCT 116 C355(1.04); C212(1.43); C376(1.46)  LDD0669  [4]
 LDCM0353  AC87 HCT 116 C355(0.87); C376(0.91); C212(1.31)  LDD0670  [4]
 LDCM0354  AC88 HCT 116 C355(0.82); C376(1.02); C212(1.57)  LDD0671  [4]
 LDCM0355  AC89 HCT 116 C355(1.16); C376(1.45); C212(2.47)  LDD0672  [4]
 LDCM0357  AC90 HCT 116 C355(0.90); C376(1.22); C212(1.24)  LDD0674  [4]
 LDCM0358  AC91 HCT 116 C355(1.23); C212(1.37); C376(1.62)  LDD0675  [4]
 LDCM0359  AC92 HCT 116 C355(1.34); C212(1.51); C376(1.75)  LDD0676  [4]
 LDCM0360  AC93 HCT 116 C355(0.73); C376(1.03); C212(1.08)  LDD0677  [4]
 LDCM0361  AC94 HCT 116 C355(1.03); C376(1.28); C212(1.78)  LDD0678  [4]
 LDCM0362  AC95 HCT 116 C355(0.81); C376(1.09); C212(1.24)  LDD0679  [4]
 LDCM0363  AC96 HCT 116 C355(1.07); C212(1.46); C376(1.67)  LDD0680  [4]
 LDCM0364  AC97 HCT 116 C355(0.97); C212(1.33); C376(1.80)  LDD0681  [4]
 LDCM0365  AC98 HCT 116 C355(1.16)  LDD0682  [4]
 LDCM0366  AC99 HCT 116 C355(1.01)  LDD0683  [4]
 LDCM0248  AKOS034007472 HCT 116 C212(0.72)  LDD0565  [4]
 LDCM0356  AKOS034007680 HCT 116 C212(0.86)  LDD0673  [4]
 LDCM0275  AKOS034007705 HCT 116 C212(0.63)  LDD0592  [4]
 LDCM0367  CL1 HCT 116 C355(0.82); C376(1.18); C212(1.29)  LDD0684  [4]
 LDCM0368  CL10 HCT 116 C355(0.68); C212(1.24); C376(1.29)  LDD0685  [4]
 LDCM0369  CL100 HCT 116 C376(0.64); C212(0.95)  LDD0686  [4]
 LDCM0370  CL101 HCT 116 C212(0.87)  LDD0687  [4]
 LDCM0371  CL102 HCT 116 C212(0.80)  LDD0688  [4]
 LDCM0372  CL103 HCT 116 C212(0.74)  LDD0689  [4]
 LDCM0373  CL104 HCT 116 C212(0.67)  LDD0690  [4]
 LDCM0374  CL105 HCT 116 C355(0.90); C376(1.29)  LDD0691  [4]
 LDCM0375  CL106 HCT 116 C376(0.75); C355(0.76)  LDD0692  [4]
 LDCM0376  CL107 HCT 116 C376(0.88); C355(1.00)  LDD0693  [4]
 LDCM0377  CL108 HCT 116 C376(0.75); C355(0.90)  LDD0694  [4]
 LDCM0378  CL109 HCT 116 C355(0.80); C376(1.21)  LDD0695  [4]
 LDCM0379  CL11 HCT 116 C355(0.78); C212(1.08); C376(1.78)  LDD0696  [4]
 LDCM0380  CL110 HCT 116 C355(0.89); C376(1.06)  LDD0697  [4]
 LDCM0381  CL111 HCT 116 C376(0.80); C355(1.08)  LDD0698  [4]
 LDCM0382  CL112 HEK-293T C38(0.91)  LDD1586  [9]
 LDCM0383  CL113 HEK-293T C38(0.98)  LDD1587  [9]
 LDCM0384  CL114 HEK-293T C38(0.98)  LDD1588  [9]
 LDCM0385  CL115 HEK-293T C38(1.14)  LDD1589  [9]
 LDCM0386  CL116 HEK-293T C38(1.08)  LDD1590  [9]
 LDCM0387  CL117 HCT 116 C376(1.75)  LDD0704  [4]
 LDCM0388  CL118 HCT 116 C376(1.24)  LDD0705  [4]
 LDCM0389  CL119 HCT 116 C376(1.73)  LDD0706  [4]
 LDCM0390  CL12 HCT 116 C355(0.81); C212(1.73); C376(2.14)  LDD0707  [4]
 LDCM0391  CL120 HCT 116 C376(1.25)  LDD0708  [4]
 LDCM0392  CL121 HCT 116 C376(1.15)  LDD0709  [4]
 LDCM0393  CL122 HCT 116 C376(1.61)  LDD0710  [4]
 LDCM0394  CL123 HCT 116 C376(2.03)  LDD0711  [4]
 LDCM0395  CL124 HCT 116 C376(1.74)  LDD0712  [4]
 LDCM0396  CL125 HCT 116 C376(1.59)  LDD0713  [4]
 LDCM0397  CL126 HCT 116 C376(1.67)  LDD0714  [4]
 LDCM0398  CL127 HCT 116 C376(1.03)  LDD0715  [4]
 LDCM0399  CL128 HCT 116 C376(1.16)  LDD0716  [4]
 LDCM0400  CL13 HCT 116 C355(1.04); C212(1.25); C376(1.27)  LDD0717  [4]
 LDCM0401  CL14 HCT 116 C355(0.80); C212(1.47); C376(1.48)  LDD0718  [4]
 LDCM0402  CL15 HCT 116 C355(0.83); C212(1.42); C376(1.88)  LDD0719  [4]
 LDCM0403  CL16 HCT 116 C376(1.19)  LDD0720  [4]
 LDCM0404  CL17 HCT 116 C376(1.03); C355(1.13)  LDD0721  [4]
 LDCM0405  CL18 HCT 116 C355(0.99); C376(1.28)  LDD0722  [4]
 LDCM0406  CL19 HCT 116 C355(1.02); C376(1.28)  LDD0723  [4]
 LDCM0407  CL2 HCT 116 C355(0.72); C212(1.03); C376(1.25)  LDD0724  [4]
 LDCM0408  CL20 HCT 116 C355(1.17); C376(1.24)  LDD0725  [4]
 LDCM0409  CL21 HCT 116 C355(0.99); C376(1.27)  LDD0726  [4]
 LDCM0410  CL22 HCT 116 C355(0.78); C376(2.20)  LDD0727  [4]
 LDCM0411  CL23 HCT 116 C355(0.91); C376(1.24)  LDD0728  [4]
 LDCM0412  CL24 HCT 116 C355(0.95); C376(1.65)  LDD0729  [4]
 LDCM0413  CL25 HCT 116 C355(0.94); C376(1.56)  LDD0730  [4]
 LDCM0414  CL26 HCT 116 C355(0.88); C376(1.10)  LDD0731  [4]
 LDCM0415  CL27 HCT 116 C355(1.07); C376(1.66)  LDD0732  [4]
 LDCM0416  CL28 HCT 116 C355(1.05); C376(1.82)  LDD0733  [4]
 LDCM0417  CL29 HCT 116 C355(1.20); C376(1.45)  LDD0734  [4]
 LDCM0418  CL3 HCT 116 C212(1.28); C355(0.66); C376(1.05)  LDD0735  [4]
 LDCM0419  CL30 HCT 116 C355(1.02); C376(1.17)  LDD0736  [4]
 LDCM0420  CL31 HCT 116 C355(1.09)  LDD0737  [4]
 LDCM0421  CL32 PaTu 8988t C376(2.97)  LDD1300  [4]
 LDCM0422  CL33 PaTu 8988t C376(1.54)  LDD1301  [4]
 LDCM0423  CL34 PaTu 8988t C376(1.96)  LDD1302  [4]
 LDCM0424  CL35 PaTu 8988t C376(2.11)  LDD1303  [4]
 LDCM0425  CL36 PaTu 8988t C376(4.14)  LDD1304  [4]
 LDCM0426  CL37 PaTu 8988t C376(1.41)  LDD1305  [4]
 LDCM0428  CL39 PaTu 8988t C376(2.02)  LDD1307  [4]
 LDCM0429  CL4 HCT 116 C212(1.05); C355(0.83); C376(1.41)  LDD0746  [4]
 LDCM0430  CL40 PaTu 8988t C376(1.51)  LDD1309  [4]
 LDCM0431  CL41 PaTu 8988t C376(1.43)  LDD1310  [4]
 LDCM0432  CL42 PaTu 8988t C376(1.15)  LDD1311  [4]
 LDCM0433  CL43 PaTu 8988t C376(1.39)  LDD1312  [4]
 LDCM0434  CL44 PaTu 8988t C376(1.38)  LDD1313  [4]
 LDCM0435  CL45 PaTu 8988t C376(2.26)  LDD1314  [4]
 LDCM0436  CL46 HCT 116 C376(1.42)  LDD0753  [4]
 LDCM0437  CL47 HCT 116 C376(1.34)  LDD0754  [4]
 LDCM0438  CL48 HCT 116 C376(1.16)  LDD0755  [4]
 LDCM0439  CL49 HCT 116 C376(0.85)  LDD0756  [4]
 LDCM0440  CL5 HCT 116 C212(1.09); C355(0.76); C376(1.07)  LDD0757  [4]
 LDCM0441  CL50 HCT 116 C376(1.14)  LDD0758  [4]
 LDCM0442  CL51 HCT 116 C376(1.23)  LDD0759  [4]
 LDCM0443  CL52 HCT 116 C376(1.25)  LDD0760  [4]
 LDCM0444  CL53 HCT 116 C376(1.02)  LDD0761  [4]
 LDCM0445  CL54 HCT 116 C376(1.33)  LDD0762  [4]
 LDCM0446  CL55 HCT 116 C376(0.96)  LDD0763  [4]
 LDCM0447  CL56 HCT 116 C376(1.07)  LDD0764  [4]
 LDCM0448  CL57 HCT 116 C376(1.11)  LDD0765  [4]
 LDCM0449  CL58 HCT 116 C376(0.95)  LDD0766  [4]
 LDCM0450  CL59 HCT 116 C376(1.11)  LDD0767  [4]
 LDCM0451  CL6 HCT 116 C212(1.34); C355(1.03); C376(1.86)  LDD0768  [4]
 LDCM0452  CL60 HCT 116 C376(1.22)  LDD0769  [4]
 LDCM0453  CL61 HCT 116 C376(1.00)  LDD0770  [4]
 LDCM0454  CL62 HCT 116 C376(1.29)  LDD0771  [4]
 LDCM0455  CL63 HCT 116 C376(1.35)  LDD0772  [4]
 LDCM0456  CL64 HCT 116 C376(1.25)  LDD0773  [4]
 LDCM0457  CL65 HCT 116 C376(1.07)  LDD0774  [4]
 LDCM0458  CL66 HCT 116 C376(1.22)  LDD0775  [4]
 LDCM0459  CL67 HCT 116 C376(1.13)  LDD0776  [4]
 LDCM0460  CL68 HCT 116 C376(1.22)  LDD0777  [4]
 LDCM0461  CL69 HCT 116 C376(1.57)  LDD0778  [4]
 LDCM0462  CL7 HCT 116 C212(1.47); C355(0.90); C376(1.13)  LDD0779  [4]
 LDCM0463  CL70 HCT 116 C376(0.96)  LDD0780  [4]
 LDCM0464  CL71 HCT 116 C376(1.11)  LDD0781  [4]
 LDCM0465  CL72 HCT 116 C376(1.12)  LDD0782  [4]
 LDCM0466  CL73 HCT 116 C376(1.26)  LDD0783  [4]
 LDCM0467  CL74 HCT 116 C376(1.22)  LDD0784  [4]
 LDCM0469  CL76 HCT 116 C376(0.63)  LDD0786  [4]
 LDCM0470  CL77 HCT 116 C376(0.55)  LDD0787  [4]
 LDCM0471  CL78 HCT 116 C376(0.53)  LDD0788  [4]
 LDCM0472  CL79 HCT 116 C376(0.72)  LDD0789  [4]
 LDCM0473  CL8 HCT 116 C212(1.22); C355(0.75); C376(2.52)  LDD0790  [4]
 LDCM0474  CL80 HCT 116 C376(0.61)  LDD0791  [4]
 LDCM0475  CL81 HCT 116 C376(0.56)  LDD0792  [4]
 LDCM0476  CL82 HCT 116 C376(0.69)  LDD0793  [4]
 LDCM0477  CL83 HCT 116 C376(0.83)  LDD0794  [4]
 LDCM0478  CL84 HCT 116 C376(0.69)  LDD0795  [4]
 LDCM0479  CL85 HCT 116 C376(0.56)  LDD0796  [4]
 LDCM0480  CL86 HCT 116 C376(0.62)  LDD0797  [4]
 LDCM0481  CL87 HCT 116 C376(0.69)  LDD0798  [4]
 LDCM0482  CL88 HCT 116 C376(0.48)  LDD0799  [4]
 LDCM0483  CL89 HCT 116 C376(0.64)  LDD0800  [4]
 LDCM0484  CL9 HCT 116 C212(1.32); C355(1.03); C376(1.48)  LDD0801  [4]
 LDCM0485  CL90 HCT 116 C376(0.59)  LDD0802  [4]
 LDCM0486  CL91 HCT 116 C212(0.79); C376(1.07)  LDD0803  [4]
 LDCM0487  CL92 HCT 116 C212(0.79); C376(0.80)  LDD0804  [4]
 LDCM0488  CL93 HCT 116 C212(0.72); C376(0.96)  LDD0805  [4]
 LDCM0489  CL94 HCT 116 C212(0.91); C376(0.83)  LDD0806  [4]
 LDCM0490  CL95 HCT 116 C212(1.17); C376(0.67)  LDD0807  [4]
 LDCM0491  CL96 HCT 116 C212(0.79); C376(0.71)  LDD0808  [4]
 LDCM0492  CL97 HCT 116 C212(0.78); C376(0.93)  LDD0809  [4]
 LDCM0493  CL98 HCT 116 C212(0.96); C376(1.01)  LDD0810  [4]
 LDCM0494  CL99 HCT 116 C212(0.88); C376(1.21)  LDD0811  [4]
 LDCM0495  E2913 HEK-293T C38(1.29)  LDD1698  [9]
 LDCM0468  Fragment33 HCT 116 C376(1.09)  LDD0785  [4]
 LDCM0427  Fragment51 PaTu 8988t C376(1.51)  LDD1306  [4]
 LDCM0022  KB02 AGS C444(2.88)  LDD2263  [10]
 LDCM0023  KB03 MDA-MB-231 C38(1.46)  LDD1701  [11]
 LDCM0024  KB05 NCI-N87 C444(2.57)  LDD3364  [10]
 LDCM0014  Panhematin HEK-293T 3.46  LDD0062  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 45 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
5'-AMP-activated protein kinase subunit beta-2 (PRKAB2) 5'-AMP-activated protein kinase beta subunit family O43741
Paraplegin (SPG7) AAA ATPase family; Peptidase M41 family Q9UQ90
Cell division cycle protein 23 homolog (CDC23) APC8/CDC23 family Q9UJX2
DNA-directed RNA polymerases I and III subunit RPAC1 (POLR1C) Archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family O15160
60 kDa heat shock protein, mitochondrial (HSPD1) Chaperonin (HSP60) family P10809
Histone-lysine N-methyltransferase SUV39H1 (SUV39H1) Histone-lysine methyltransferase family O43463
Glutamine--tRNA ligase (QARS1) Class-I aminoacyl-tRNA synthetase family P47897
Thioredoxin-like protein 4A (TXNL4A) DIM1 family P83876
Peroxisomal bifunctional enzyme (EHHADH) Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase family Q08426
Glycerate kinase (GLYCTK) Glycerate kinase type-2 family Q8IVS8
ATP-dependent RNA helicase SUPV3L1, mitochondrial (SUPV3L1) Helicase family Q8IYB8
Protein mab-21-like 3 (MAB21L3) Mab-21 family Q8N8X9
Histone acetyltransferase KAT5 (KAT5) MYST (SAS/MOZ) family Q92993
Protein N-terminal glutamine amidohydrolase (NTAQ1) NTAQ1 family Q96HA8
Minor histocompatibility antigen H13 (HM13) Peptidase A22B family Q8TCT9
Ubiquitin carboxyl-terminal hydrolase 2 (USP2) Peptidase C19 family O75604
Ubiquitin thioesterase OTUB2 (OTUB2) Peptidase C65 family Q96DC9
Proteasome subunit alpha type-1 (PSMA1) Peptidase T1A family P25786
Testis-specific serine/threonine-protein kinase 2 (TSSK2) CAMK Ser/Thr protein kinase family Q96PF2
Testis-specific serine/threonine-protein kinase 3 (TSSK3) CAMK Ser/Thr protein kinase family Q96PN8
5'-AMP-activated protein kinase catalytic subunit alpha-2 (PRKAA2) CAMK Ser/Thr protein kinase family P54646
Casein kinase I isoform delta (CSNK1D) CK1 Ser/Thr protein kinase family P48730
Cyclin-dependent kinase 18 (CDK18) CMGC Ser/Thr protein kinase family Q07002
Cyclin-dependent kinase-like 3 (CDKL3) CMGC Ser/Thr protein kinase family Q8IVW4
Mitogen-activated protein kinase 1 (MAPK1) CMGC Ser/Thr protein kinase family P28482
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) CMGC Ser/Thr protein kinase family Q13627
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (DYRK1B) CMGC Ser/Thr protein kinase family Q9Y463
Dual specificity tyrosine-phosphorylation-regulated kinase 2 (DYRK2) CMGC Ser/Thr protein kinase family Q92630
Serine/threonine-protein kinase Nek6 (NEK6) NEK Ser/Thr protein kinase family Q9HC98
Proto-oncogene serine/threonine-protein kinase mos (MOS) Ser/Thr protein kinase family P00540
Tyrosine-protein kinase Lck (LCK) Tyr protein kinase family P06239
Dual specificity protein phosphatase 4 (DUSP4) Protein-tyrosine phosphatase family Q13115
Exosome complex component RRP46 (EXOSC5) RNase PH family Q9NQT4
GTP-binding protein GEM (GEM) RGK family P55040
Ras-related C3 botulinum toxin substrate 1 (RAC1) Rho family P63000
Kinesin-like protein KIFC3 (KIFC3) Kinesin family Q9BVG8
Guanine nucleotide-binding protein-like 3-like protein (GNL3L) TRAFAC class YlqF/YawG GTPase family Q9NVN8
Tripartite motif-containing protein 42 (TRIM42) TRIM/RBCC family Q8IWZ5
Apoptosis-enhancing nuclease (AEN) . Q8WTP8
DCN1-like protein 1 (DCUN1D1) . Q96GG9
E3 ubiquitin-protein ligase FANCL (FANCL) . Q9NW38
E3 ubiquitin-protein ligase NRDP1 (RNF41) . Q9H4P4
Germ cell-less protein-like 2 (GMCL2) . Q8NEA9
Tripartite motif-containing protein 29 (TRIM29) . Q14134
Ubiquitin-associated and SH3 domain-containing protein B (UBASH3B) . Q8TF42
Transporter and channel
Click To Hide/Show 9 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Metal transporter CNNM3 (CNNM3) ACDP family Q8NE01
AP-1 complex subunit mu-1 (AP1M1) Adaptor complexes medium subunit family Q9BXS5
Cation channel sperm-associated protein 1 (CATSPER1) Cation channel sperm-associated (TC 1.A.1.19) family Q8NEC5
Importin subunit alpha-1 (KPNA2) Importin alpha family P52292
ADP/ATP translocase 3 (SLC25A6) Mitochondrial carrier (TC 2.A.29) family P12236
Nuclear cap-binding protein subunit 2 (NCBP2) RRM NCBP2 family P52298
Sorting nexin-31 (SNX31) Sorting nexin family Q8N9S9
SH3 and cysteine-rich domain-containing protein (STAC) . Q99469
Sodium channel modifier 1 (SCNM1) . Q9BWG6
Transcription factor
Click To Hide/Show 23 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Homeobox protein Hox-B9 (HOXB9) Abd-B homeobox family P17482
REST corepressor 3 (RCOR3) CoREST family Q9P2K3
Vascular endothelial zinc finger 1 (VEZF1) Krueppel C2H2-type zinc-finger protein family Q14119
Zinc finger protein 124 (ZNF124) Krueppel C2H2-type zinc-finger protein family Q15973
Zinc finger protein 20 (ZNF20) Krueppel C2H2-type zinc-finger protein family P17024
Zinc finger protein 417 (ZNF417) Krueppel C2H2-type zinc-finger protein family Q8TAU3
Zinc finger protein 490 (ZNF490) Krueppel C2H2-type zinc-finger protein family Q9ULM2
Zinc finger protein 572 (ZNF572) Krueppel C2H2-type zinc-finger protein family Q7Z3I7
Zinc finger protein 648 (ZNF648) Krueppel C2H2-type zinc-finger protein family Q5T619
Zinc finger protein with KRAB and SCAN domains 3 (ZKSCAN3) Krueppel C2H2-type zinc-finger protein family Q9BRR0
PHD finger protein 1 (PHF1) Polycomblike family O43189
PHD finger protein 19 (PHF19) Polycomblike family Q5T6S3
Krueppel-like factor 11 (KLF11) Sp1 C2H2-type zinc-finger protein family O14901
Metastasis-associated protein MTA1 (MTA1) . Q13330
THAP domain-containing protein 10 (THAP10) . Q9P2Z0
THAP domain-containing protein 7 (THAP7) . Q9BT49
Transcriptional enhancer factor TEF-3 (TEAD4) . Q15561
Upstream stimulatory factor 2 (USF2) . Q15853
Zinc finger and BTB domain-containing protein 25 (ZBTB25) . P24278
Zinc finger CCCH-type with G patch domain-containing protein (ZGPAT) . Q8N5A5
Zinc finger protein 408 (ZNF408) . Q9H9D4
Zinc finger protein 426 (ZNF426) . Q9BUY5
Zinc finger protein 581 (ZNF581) . Q9P0T4
Immunoglobulin
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Intercellular adhesion molecule 5 (ICAM5) ICAM family Q9UMF0
Other
Click To Hide/Show 100 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Atos homolog protein B (ATOSB) ATOS family Q7L5A3
ATP synthase mitochondrial F1 complex assembly factor 2 (ATPAF2) ATP12 family Q8N5M1
Plakophilin-4 (PKP4) Beta-catenin family Q99569
Protein BEX2 (BEX2) BEX family Q9BXY8
Bystin (BYSL) Bystin family Q13895
Cyclin-dependent kinase inhibitor 1 (CDKN1A) CDI family P38936
Cilia- and flagella-associated protein 206 (CFAP206) CFAP206 family Q8IYR0
Cysteine-rich hydrophobic domain-containing protein 2 (CHIC2) CHIC family Q9UKJ5
CWF19-like protein 2 (CWF19L2) CWF19 family Q2TBE0
Cyclin-C (CCNC) Cyclin family P24863
Cyclin-K (CCNK) Cyclin family O75909
Cyclin-G1 (CCNG1) Cyclin family P51959
Eukaryotic translation initiation factor 3 subunit D (EIF3D) EIF-3 subunit D family O15371
Activator of basal transcription 1 (ABT1) ESF2/ABP1 family Q9ULW3
Eukaryotic translation initiation factor 4E type 2 (EIF4E2) Eukaryotic initiation factor 4E family O60573
Protein FAM124B (FAM124B) FAM124 family Q9H5Z6
Protein FAM161A (FAM161A) FAM161 family Q3B820
Protein FAM221B (FAM221B) FAM221 family A6H8Z2
Protein FAM50B (FAM50B) FAM50 family Q9Y247
Protein FAM74A4/A6 (FAM74A4; FAM74A6) FAM74 family Q5TZK3
Protein FAM90A1 (FAM90A1) FAM90 family Q86YD7
Protein fem-1 homolog C (FEM1C) Fem-1 family Q96JP0
Inactive peptidyl-prolyl cis-trans isomerase FKBP6 (FKBP6) FKBP6 family O75344
Protein FRG1 (FRG1) FRG1 family Q14331
PDZ domain-containing protein GIPC2 (GIPC2) GIPC family Q8TF65
Protein DGCR6L (DGCR6L) Gonadal family Q9BY27
Growth factor receptor-bound protein 2 (GRB2) GRB2/sem-5/DRK family P62993
Fibroblast growth factor 12 (FGF12) Heparin-binding growth factors family P61328
Homer protein homolog 2 (HOMER2) Homer family Q9NSB8
Axonemal dynein light intermediate polypeptide 1 (DNALI1) Inner dynein arm light chain family O14645
Kazrin (KAZN) Kazrin family Q674X7
Protein MEMO1 (MEMO1) MEMO1 family Q9Y316
MICOS complex subunit MIC19 (CHCHD3) MICOS complex subunit Mic19 family Q9NX63
Large ribosomal subunit protein mL64 (GADD45GIP1) Mitochondrion-specific ribosomal protein mL64 family Q8TAE8
Myozenin-1 (MYOZ1) Myozenin family Q9NP98
60S ribosome subunit biogenesis protein NIP7 homolog (NIP7) NIP7 family Q9Y221
Pre-mRNA-splicing factor 18 (PRPF18) PRP18 family Q99633
U4/U6 small nuclear ribonucleoprotein Prp31 (PRPF31) PRP31 family Q8WWY3
Rho GTPase-activating protein 32 (ARHGAP32) PX domain-containing GAP family A7KAX9
RNA guanine-N7 methyltransferase activating subunit (RAMAC) RAM family Q9BTL3
DNA repair protein RAD51 homolog 4 (RAD51D) RecA family O75771
Ras and Rab interactor 1 (RIN1) RIN (Ras interaction/interference) family Q13671
RNA-binding protein 15 (RBM15) RRM Spen family Q96T37
Shiftless antiviral inhibitor of ribosomal frameshifting protein (SHFL) SHFL family Q9NUL5
Pre-mRNA-splicing factor SLU7 (SLU7) SLU7 family O95391
Biglycan (BGN) Small leucine-rich proteoglycan (SLRP) family P21810
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 (SMARCD1) SMARCD family Q96GM5
SNW domain-containing protein 1 (SNW1) SNW family Q13573
Spermatogenesis-associated protein 2 (SPATA2) SPATA2 family Q9UM82
Spermatogenesis-associated protein 24 (SPATA24) SPATA24 family Q86W54
Speriolin-like protein (SPATC1L) Speriolin family Q9H0A9
Synaptotagmin-17 (SYT17) Synaptotagmin family Q9BSW7
Trichoplein keratin filament-binding protein (TCHP) TCHP family Q9BT92
Transcription elongation factor A protein 2 (TCEA2) TFS-II family Q15560
Translin-associated protein X (TSNAX) Translin family Q99598
Centrosomal protein CEP57L1 (CEP57L1) Translokin family Q8IYX8
UPF0488 protein C8orf33 (C8orf33) UPF0488 family Q9H7E9
AFG2-interacting ribosome maturation factor (AIRIM) . Q9NX04
Armadillo repeat-containing protein 7 (ARMC7) . Q9H6L4
Bromo adjacent homology domain-containing 1 protein (BAHD1) . Q8TBE0
Calcium-binding protein 5 (CABP5) . Q9NP86
CAP-Gly domain-containing linker protein 4 (CLIP4) . Q8N3C7
Caspase recruitment domain-containing protein 9 (CARD9) . Q9H257
Cation channel sperm-associated targeting subunit tau (C2CD6) . Q53TS8
Chromobox protein homolog 8 (CBX8) . Q9HC52
Cytoplasmic protein NCK2 (NCK2) . O43639
Factor associated with metabolism and energy (CCDC198) . Q9NVL8
FERM domain-containing protein 6 (FRMD6) . Q96NE9
Fibronectin type III domain-containing protein 11 (FNDC11) . Q9BVV2
G patch domain and ankyrin repeat-containing protein 1 (GPANK1) . O95872
G patch domain-containing protein 2-like (GPATCH2L) . Q9NWQ4
GRIP and coiled-coil domain-containing protein 1 (GCC1) . Q96CN9
INO80 complex subunit B (INO80B) . Q9C086
IQ domain-containing protein N (IQCN) . Q9H0B3
LIM and SH3 domain protein 1 (LASP1) . Q14847
Melanoma-associated antigen B4 (MAGEB4) . O15481
MORN repeat-containing protein 3 (MORN3) . Q6PF18
Mortality factor 4-like protein 1 (MORF4L1) . Q9UBU8
Mortality factor 4-like protein 2 (MORF4L2) . Q15014
Nebulette (NEBL) . O76041
Phostensin (PPP1R18) . Q6NYC8
Pleckstrin homology domain-containing family N member 1 (PLEKHN1) . Q494U1
Polyglutamine-binding protein 1 (PQBP1) . O60828
Proline-rich protein 35 (PRR35) . P0CG20
Protein lin-37 homolog (LIN37) . Q96GY3
Putative ankyrin repeat domain-containing protein 26-like 1 (ANKRD36BP1) . Q96IX9
Putative Wilms tumor upstream neighbor 1 gene protein (WT1-AS) . Q06250
RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 (RHNO1) . Q9BSD3
Receptor-transporting protein 5 (RTP5) . Q14D33
Rhombotin-1 (LMO1) . P25800
Rhombotin-2 (LMO2) . P25791
RNA-binding protein 41 (RBM41) . Q96IZ5
SH2 domain-containing protein 4A (SH2D4A) . Q9H788
SH3 domain-containing kinase-binding protein 1 (SH3KBP1) . Q96B97
Small integral membrane protein 3 (SMIM3) . Q9BZL3
TBC1 domain family member 7 (TBC1D7) . Q9P0N9
Tetratricopeptide repeat protein 23 (TTC23) . Q5W5X9
TNFAIP3-interacting protein 3 (TNIP3) . Q96KP6
Zinc finger matrin-type protein 2 (ZMAT2) . Q96NC0
Zinc finger MYND domain-containing protein 19 (ZMYND19) . Q96E35

References

1 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
2 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
3 A Chemical Proteomic Map of Heme-Protein Interactions. J Am Chem Soc. 2022 Aug 24;144(33):15013-15019. doi: 10.1021/jacs.2c06104. Epub 2022 Aug 12.
Mass spectrometry data entry: PXD034651
4 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
5 Tunable Amine-Reactive Electrophiles for Selective Profiling of Lysine. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202112107. doi: 10.1002/anie.202112107. Epub 2021 Dec 16.
6 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
7 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
8 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
9 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
10 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
11 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761