Details of the Target

General Information of Target

Target ID LDTP08095
Target Name Coiled-coil domain-containing protein R3HCC1L (R3HCC1L)
Gene Name R3HCC1L
Gene ID 27291
Synonyms
C10orf28; GIDRP88; Coiled-coil domain-containing protein R3HCC1L; Growth inhibition and differentiation-related protein 88; Putative mitochondrial space protein 32.1; R3H and coiled-coil domain-containing protein 1-like
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MQQESERCRVRARRPDMALYVPKARRGAVLLKTGDEEESCGSPNSVVKEKQKESSLSQKE
VFKDKPEARRLNINPDRKEHNCREEKKSSTKLRMDTCLQKTNRVCSKRGTTESKEVLSQG
QQQGAPNAGVITNAPLQRHFKPKKVECLEVETTDVTGHERILLSQACLEISEAQVPSKPF
QNVEFCDFSRHEPDGEAFEDKDLEGRIETDTKVLEILYEFPRVFSSVMKPENMIVPIKLS
SDSEIVQQSMQTSDGILNPSSGGITTTSVPGSPDGVFDQTCVDFEVESVGGIANSTGFIL
DQKDTDSIPATMGHISLSESTNDTVSPVMIRECEKNDSTADELHVKHEPPDTAVLAHETH
RDSGFKNVGDITNKACMMDTTGMSCSDHVTVDSPYVVAVRIADETSINTRSFSKFVGMSA
DATPLHVARSGNDTEDFSNPSACSDIYGESISSHFTESTGKLIESLSDCASSLPIKKIAG
SNYNTFLDSELSMLNGTKVLSDSAVGIDLGSTGDTTEALHELRTAEEFKTEEQDDSGSIE
FGVSFPDRESSSMETSIEPKATETSHTEGITAIEESWESMFNDDGDCLDPRLLQEGILMH
IKPENHCSKLSGNTKSRESIQEPRSDYYNHEVPDIDLSDCEFPHVIEIYDFPQEFHTEDL
LRVFCSYQKKGFDIKWVDDTHALGVFSSPITARDALGIKHTMVKIRPLSQATRAAKAKAR
AYAEFLQPAKERPETSAALARRLVISALGVRSKQSKTEREAELKKLQEARERKRLEAKQR
EDIWEGRDQSTV
Target Bioclass
Other
Uniprot ID
Q7Z5L2
Ensemble ID
ENST00000370586.6
HGNC ID
HGNC:23512

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 10 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		12.25  LDD0402  [1]
DA-P3
 Probe Info  		5.85  LDD0180  [2]
AHL-Pu-1
 Probe Info  		C443(2.69)  LDD0170  [3]
DBIA
 Probe Info  		C665(1.77)  LDD0080  [4]
IA-alkyne
 Probe Info  		C40(0.00); C147(0.00)  LDD0165  [5]
NAIA_4
 Probe Info  		N.A.  LDD2226  [6]
NAIA_5
 Probe Info  		C469(0.00); C147(0.00)  LDD2225  [6]
IPM
 Probe Info  		C469(0.00); C97(0.00); C665(0.00); C443(0.00)  LDD2156  [7]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [8]
AOyne
 Probe Info  		15.00  LDD0443  [9]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA DM93 C443(2.69)  LDD0170  [3]
 LDCM0026  4SU-RNA+native RNA DM93 C443(2.71)  LDD0171  [3]
 LDCM0214  AC1 HCT 116 C665(1.22)  LDD0531  [4]
 LDCM0215  AC10 HCT 116 C665(1.41)  LDD0532  [4]
 LDCM0216  AC100 HCT 116 C665(1.15)  LDD0533  [4]
 LDCM0217  AC101 HCT 116 C665(1.06)  LDD0534  [4]
 LDCM0218  AC102 HCT 116 C665(1.21)  LDD0535  [4]
 LDCM0219  AC103 HCT 116 C665(1.43)  LDD0536  [4]
 LDCM0220  AC104 HCT 116 C665(1.70)  LDD0537  [4]
 LDCM0221  AC105 HCT 116 C665(1.26)  LDD0538  [4]
 LDCM0222  AC106 HCT 116 C665(1.79)  LDD0539  [4]
 LDCM0223  AC107 HCT 116 C665(1.36)  LDD0540  [4]
 LDCM0224  AC108 HCT 116 C665(0.99)  LDD0541  [4]
 LDCM0225  AC109 HCT 116 C665(1.03)  LDD0542  [4]
 LDCM0226  AC11 HCT 116 C665(1.51)  LDD0543  [4]
 LDCM0227  AC110 HCT 116 C665(1.10)  LDD0544  [4]
 LDCM0228  AC111 HCT 116 C665(1.16)  LDD0545  [4]
 LDCM0229  AC112 HCT 116 C665(1.34)  LDD0546  [4]
 LDCM0230  AC113 HCT 116 C665(0.99)  LDD0547  [4]
 LDCM0231  AC114 HCT 116 C665(1.20)  LDD0548  [4]
 LDCM0232  AC115 HCT 116 C665(1.39)  LDD0549  [4]
 LDCM0233  AC116 HCT 116 C665(1.35)  LDD0550  [4]
 LDCM0234  AC117 HCT 116 C665(1.28)  LDD0551  [4]
 LDCM0235  AC118 HCT 116 C665(1.14)  LDD0552  [4]
 LDCM0236  AC119 HCT 116 C665(1.36)  LDD0553  [4]
 LDCM0237  AC12 HCT 116 C665(1.21)  LDD0554  [4]
 LDCM0238  AC120 HCT 116 C665(1.47)  LDD0555  [4]
 LDCM0239  AC121 HCT 116 C665(1.03)  LDD0556  [4]
 LDCM0240  AC122 HCT 116 C665(1.03)  LDD0557  [4]
 LDCM0241  AC123 HCT 116 C665(1.19)  LDD0558  [4]
 LDCM0242  AC124 HCT 116 C665(1.02)  LDD0559  [4]
 LDCM0243  AC125 HCT 116 C665(1.12)  LDD0560  [4]
 LDCM0244  AC126 HCT 116 C665(1.32)  LDD0561  [4]
 LDCM0245  AC127 HCT 116 C665(1.36)  LDD0562  [4]
 LDCM0246  AC128 HCT 116 C665(1.07)  LDD0563  [4]
 LDCM0247  AC129 HCT 116 C665(0.69)  LDD0564  [4]
 LDCM0249  AC130 HCT 116 C665(0.97)  LDD0566  [4]
 LDCM0250  AC131 HCT 116 C665(0.76)  LDD0567  [4]
 LDCM0251  AC132 HCT 116 C665(0.69)  LDD0568  [4]
 LDCM0252  AC133 HCT 116 C665(1.01)  LDD0569  [4]
 LDCM0253  AC134 HCT 116 C665(1.08)  LDD0570  [4]
 LDCM0254  AC135 HCT 116 C665(1.15)  LDD0571  [4]
 LDCM0255  AC136 HCT 116 C665(1.07)  LDD0572  [4]
 LDCM0256  AC137 HCT 116 C665(0.73)  LDD0573  [4]
 LDCM0257  AC138 HCT 116 C665(1.02)  LDD0574  [4]
 LDCM0258  AC139 HCT 116 C665(1.07)  LDD0575  [4]
 LDCM0259  AC14 HCT 116 C665(1.42)  LDD0576  [4]
 LDCM0260  AC140 HCT 116 C665(0.96)  LDD0577  [4]
 LDCM0261  AC141 HCT 116 C665(0.91)  LDD0578  [4]
 LDCM0262  AC142 HCT 116 C665(0.77)  LDD0579  [4]
 LDCM0263  AC143 HCT 116 C665(1.19)  LDD0580  [4]
 LDCM0264  AC144 HCT 116 C665(1.57)  LDD0581  [4]
 LDCM0265  AC145 HCT 116 C665(1.79)  LDD0582  [4]
 LDCM0266  AC146 HCT 116 C665(1.64)  LDD0583  [4]
 LDCM0267  AC147 HCT 116 C665(2.00)  LDD0584  [4]
 LDCM0268  AC148 HCT 116 C665(2.80)  LDD0585  [4]
 LDCM0269  AC149 HCT 116 C665(2.14)  LDD0586  [4]
 LDCM0270  AC15 HCT 116 C665(1.40)  LDD0587  [4]
 LDCM0271  AC150 HCT 116 C665(1.37)  LDD0588  [4]
 LDCM0272  AC151 HCT 116 C665(1.66)  LDD0589  [4]
 LDCM0273  AC152 HCT 116 C665(2.21)  LDD0590  [4]
 LDCM0274  AC153 HCT 116 C665(2.28)  LDD0591  [4]
 LDCM0621  AC154 HCT 116 C665(1.72)  LDD2158  [4]
 LDCM0622  AC155 HCT 116 C665(1.38)  LDD2159  [4]
 LDCM0623  AC156 HCT 116 C665(1.22)  LDD2160  [4]
 LDCM0624  AC157 HCT 116 C665(1.26)  LDD2161  [4]
 LDCM0276  AC17 HEK-293T C186(1.13)  LDD0874  [4]
 LDCM0277  AC18 HEK-293T C186(1.24)  LDD0875  [4]
 LDCM0278  AC19 HEK-293T C186(1.32)  LDD0876  [4]
 LDCM0279  AC2 HCT 116 C665(1.16)  LDD0596  [4]
 LDCM0280  AC20 HEK-293T C186(0.99)  LDD0878  [4]
 LDCM0281  AC21 HEK-293T C186(1.44)  LDD0879  [4]
 LDCM0282  AC22 HEK-293T C186(0.92)  LDD0880  [4]
 LDCM0283  AC23 HEK-293T C186(1.29)  LDD0881  [4]
 LDCM0284  AC24 HEK-293T C186(1.28)  LDD0882  [4]
 LDCM0285  AC25 HEK-293T C186(0.56); C665(0.85)  LDD0883  [4]
 LDCM0286  AC26 HEK-293T C186(0.71); C665(0.86)  LDD0884  [4]
 LDCM0287  AC27 HEK-293T C186(0.77); C665(1.00)  LDD0885  [4]
 LDCM0288  AC28 HEK-293T C186(1.61); C665(0.86)  LDD0886  [4]
 LDCM0289  AC29 HEK-293T C186(0.75); C665(0.92)  LDD0887  [4]
 LDCM0290  AC3 HCT 116 C665(1.20)  LDD0607  [4]
 LDCM0291  AC30 HEK-293T C186(0.75); C665(0.98)  LDD0889  [4]
 LDCM0292  AC31 HEK-293T C186(0.69); C665(0.95)  LDD0890  [4]
 LDCM0293  AC32 HEK-293T C186(0.62); C665(0.89)  LDD0891  [4]
 LDCM0294  AC33 HEK-293T C186(0.71); C665(0.82)  LDD0892  [4]
 LDCM0295  AC34 HEK-293T C186(0.81); C665(1.02)  LDD0893  [4]
 LDCM0296  AC35 HCT 116 C665(0.93)  LDD0613  [4]
 LDCM0297  AC36 HCT 116 C665(1.09)  LDD0614  [4]
 LDCM0298  AC37 HCT 116 C665(1.14)  LDD0615  [4]
 LDCM0299  AC38 HCT 116 C665(0.96)  LDD0616  [4]
 LDCM0300  AC39 HCT 116 C665(0.96)  LDD0617  [4]
 LDCM0301  AC4 HCT 116 C665(1.46)  LDD0618  [4]
 LDCM0302  AC40 HCT 116 C665(1.27)  LDD0619  [4]
 LDCM0303  AC41 HCT 116 C665(1.37)  LDD0620  [4]
 LDCM0304  AC42 HCT 116 C665(1.16)  LDD0621  [4]
 LDCM0305  AC43 HCT 116 C665(1.29)  LDD0622  [4]
 LDCM0306  AC44 HCT 116 C665(1.38)  LDD0623  [4]
 LDCM0307  AC45 HCT 116 C665(1.28)  LDD0624  [4]
 LDCM0308  AC46 HEK-293T C186(0.98); C665(1.01)  LDD0906  [4]
 LDCM0309  AC47 HEK-293T C186(1.33); C665(1.04)  LDD0907  [4]
 LDCM0310  AC48 HEK-293T C186(1.34); C665(1.07)  LDD0908  [4]
 LDCM0311  AC49 HEK-293T C186(1.25); C665(1.10)  LDD0909  [4]
 LDCM0312  AC5 HCT 116 C665(1.30)  LDD0629  [4]
 LDCM0313  AC50 HEK-293T C186(1.32); C665(1.01)  LDD0911  [4]
 LDCM0314  AC51 HEK-293T C186(1.49); C665(1.08)  LDD0912  [4]
 LDCM0315  AC52 HEK-293T C186(1.58); C665(1.19)  LDD0913  [4]
 LDCM0316  AC53 HEK-293T C186(1.50); C665(1.03)  LDD0914  [4]
 LDCM0317  AC54 HEK-293T C186(1.62); C665(1.18)  LDD0915  [4]
 LDCM0318  AC55 HEK-293T C186(1.45); C665(1.24)  LDD0916  [4]
 LDCM0319  AC56 HEK-293T C186(1.10); C665(1.03)  LDD0917  [4]
 LDCM0320  AC57 HCT 116 C665(1.42)  LDD0637  [4]
 LDCM0321  AC58 HCT 116 C665(1.62)  LDD0638  [4]
 LDCM0322  AC59 HCT 116 C665(1.76)  LDD0639  [4]
 LDCM0323  AC6 HCT 116 C665(1.41)  LDD0640  [4]
 LDCM0324  AC60 HCT 116 C665(1.51)  LDD0641  [4]
 LDCM0325  AC61 HCT 116 C665(1.54)  LDD0642  [4]
 LDCM0326  AC62 HCT 116 C665(1.74)  LDD0643  [4]
 LDCM0327  AC63 HCT 116 C665(1.62)  LDD0644  [4]
 LDCM0328  AC64 HCT 116 C665(2.40)  LDD0645  [4]
 LDCM0329  AC65 HCT 116 C665(1.81)  LDD0646  [4]
 LDCM0330  AC66 HCT 116 C665(1.90)  LDD0647  [4]
 LDCM0331  AC67 HCT 116 C665(2.46)  LDD0648  [4]
 LDCM0332  AC68 HEK-293T C186(1.19)  LDD0930  [4]
 LDCM0333  AC69 HEK-293T C186(1.14)  LDD0931  [4]
 LDCM0334  AC7 HCT 116 C665(1.25)  LDD0651  [4]
 LDCM0335  AC70 HEK-293T C186(1.33)  LDD0933  [4]
 LDCM0336  AC71 HEK-293T C186(1.19)  LDD0934  [4]
 LDCM0337  AC72 HEK-293T C186(1.26)  LDD0935  [4]
 LDCM0338  AC73 HEK-293T C186(1.16)  LDD0936  [4]
 LDCM0339  AC74 HEK-293T C186(1.10)  LDD0937  [4]
 LDCM0340  AC75 HEK-293T C186(0.98)  LDD0938  [4]
 LDCM0341  AC76 HEK-293T C186(1.02)  LDD0939  [4]
 LDCM0342  AC77 HEK-293T C186(1.08)  LDD0940  [4]
 LDCM0343  AC78 HEK-293T C186(1.33)  LDD0941  [4]
 LDCM0344  AC79 HEK-293T C186(1.13)  LDD0942  [4]
 LDCM0345  AC8 HCT 116 C665(1.31)  LDD0662  [4]
 LDCM0346  AC80 HEK-293T C186(0.98)  LDD0944  [4]
 LDCM0347  AC81 HEK-293T C186(1.23)  LDD0945  [4]
 LDCM0348  AC82 HEK-293T C186(1.08)  LDD0946  [4]
 LDCM0349  AC83 HCT 116 C665(1.68)  LDD0666  [4]
 LDCM0350  AC84 HCT 116 C665(1.64)  LDD0667  [4]
 LDCM0351  AC85 HCT 116 C665(1.40)  LDD0668  [4]
 LDCM0352  AC86 HCT 116 C665(1.36)  LDD0669  [4]
 LDCM0353  AC87 HCT 116 C665(1.28)  LDD0670  [4]
 LDCM0354  AC88 HCT 116 C665(1.30)  LDD0671  [4]
 LDCM0355  AC89 HCT 116 C665(1.46)  LDD0672  [4]
 LDCM0357  AC90 HCT 116 C665(1.12)  LDD0674  [4]
 LDCM0358  AC91 HCT 116 C665(1.61)  LDD0675  [4]
 LDCM0359  AC92 HCT 116 C665(1.35)  LDD0676  [4]
 LDCM0360  AC93 HCT 116 C665(1.14)  LDD0677  [4]
 LDCM0361  AC94 HCT 116 C665(1.24)  LDD0678  [4]
 LDCM0362  AC95 HCT 116 C665(1.29)  LDD0679  [4]
 LDCM0363  AC96 HCT 116 C665(1.25)  LDD0680  [4]
 LDCM0364  AC97 HCT 116 C665(1.52)  LDD0681  [4]
 LDCM0365  AC98 HCT 116 C665(1.94)  LDD0682  [4]
 LDCM0366  AC99 HCT 116 C665(1.05)  LDD0683  [4]
 LDCM0248  AKOS034007472 HCT 116 C665(1.25)  LDD0565  [4]
 LDCM0356  AKOS034007680 HCT 116 C665(1.26)  LDD0673  [4]
 LDCM0275  AKOS034007705 HCT 116 C665(1.99)  LDD0592  [4]
 LDCM0632  CL-Sc Hep-G2 C147(20.00)  LDD2227  [6]
 LDCM0367  CL1 HCT 116 C665(0.93)  LDD0684  [4]
 LDCM0368  CL10 HCT 116 C665(0.81)  LDD0685  [4]
 LDCM0369  CL100 HCT 116 C665(1.05)  LDD0686  [4]
 LDCM0370  CL101 HCT 116 C665(1.49)  LDD0687  [4]
 LDCM0371  CL102 HCT 116 C665(1.14)  LDD0688  [4]
 LDCM0372  CL103 HCT 116 C665(1.12)  LDD0689  [4]
 LDCM0373  CL104 HCT 116 C665(1.27)  LDD0690  [4]
 LDCM0374  CL105 HEK-293T C186(0.95)  LDD0972  [4]
 LDCM0375  CL106 HEK-293T C186(0.87)  LDD0973  [4]
 LDCM0376  CL107 HEK-293T C186(1.28)  LDD0974  [4]
 LDCM0377  CL108 HEK-293T C186(1.15)  LDD0975  [4]
 LDCM0378  CL109 HEK-293T C186(1.06)  LDD0976  [4]
 LDCM0379  CL11 HCT 116 C665(0.90)  LDD0696  [4]
 LDCM0380  CL110 HEK-293T C186(1.29)  LDD0978  [4]
 LDCM0381  CL111 HEK-293T C186(1.24)  LDD0979  [4]
 LDCM0382  CL112 HEK-293T C186(0.78); C665(0.89)  LDD0980  [4]
 LDCM0383  CL113 HEK-293T C186(0.85); C665(0.90)  LDD0981  [4]
 LDCM0384  CL114 HEK-293T C186(0.73); C665(0.84)  LDD0982  [4]
 LDCM0385  CL115 HEK-293T C186(0.78); C665(1.00)  LDD0983  [4]
 LDCM0386  CL116 HEK-293T C186(0.78); C665(0.91)  LDD0984  [4]
 LDCM0387  CL117 HCT 116 C665(0.98)  LDD0704  [4]
 LDCM0388  CL118 HCT 116 C665(1.01)  LDD0705  [4]
 LDCM0389  CL119 HCT 116 C665(0.95)  LDD0706  [4]
 LDCM0390  CL12 HCT 116 C665(0.73)  LDD0707  [4]
 LDCM0391  CL120 HCT 116 C665(1.12)  LDD0708  [4]
 LDCM0392  CL121 HEK-293T C186(1.30); C665(1.15)  LDD0990  [4]
 LDCM0393  CL122 HEK-293T C186(1.09); C665(1.06)  LDD0991  [4]
 LDCM0394  CL123 HEK-293T C186(1.23); C665(1.52)  LDD0992  [4]
 LDCM0395  CL124 HEK-293T C186(1.31); C665(1.11)  LDD0993  [4]
 LDCM0396  CL125 HCT 116 C665(1.10)  LDD0713  [4]
 LDCM0397  CL126 HCT 116 C665(1.07)  LDD0714  [4]
 LDCM0398  CL127 HCT 116 C665(1.17)  LDD0715  [4]
 LDCM0399  CL128 HCT 116 C665(2.01)  LDD0716  [4]
 LDCM0400  CL13 HCT 116 C665(0.79)  LDD0717  [4]
 LDCM0401  CL14 HCT 116 C665(0.83)  LDD0718  [4]
 LDCM0402  CL15 HCT 116 C665(0.70)  LDD0719  [4]
 LDCM0403  CL16 HEK-293T C186(1.05)  LDD1001  [4]
 LDCM0404  CL17 HEK-293T C186(1.13)  LDD1002  [4]
 LDCM0405  CL18 HEK-293T C186(1.10)  LDD1003  [4]
 LDCM0406  CL19 HEK-293T C186(0.92)  LDD1004  [4]
 LDCM0407  CL2 HCT 116 C665(1.00)  LDD0724  [4]
 LDCM0408  CL20 HEK-293T C186(1.28)  LDD1006  [4]
 LDCM0409  CL21 HEK-293T C186(0.88)  LDD1007  [4]
 LDCM0410  CL22 HEK-293T C186(0.94)  LDD1008  [4]
 LDCM0411  CL23 HEK-293T C186(1.09)  LDD1009  [4]
 LDCM0412  CL24 HEK-293T C186(1.18)  LDD1010  [4]
 LDCM0413  CL25 HEK-293T C186(1.13)  LDD1011  [4]
 LDCM0414  CL26 HEK-293T C186(1.09)  LDD1012  [4]
 LDCM0415  CL27 HEK-293T C186(1.29)  LDD1013  [4]
 LDCM0416  CL28 HEK-293T C186(1.23)  LDD1014  [4]
 LDCM0417  CL29 HEK-293T C186(1.17)  LDD1015  [4]
 LDCM0418  CL3 HCT 116 C665(0.69)  LDD0735  [4]
 LDCM0419  CL30 HEK-293T C186(0.98)  LDD1017  [4]
 LDCM0420  CL31 HCT 116 C665(0.88)  LDD0737  [4]
 LDCM0421  CL32 HCT 116 C665(0.92)  LDD0738  [4]
 LDCM0422  CL33 HCT 116 C665(0.87)  LDD0739  [4]
 LDCM0423  CL34 HCT 116 C665(1.07)  LDD0740  [4]
 LDCM0424  CL35 HCT 116 C665(1.05)  LDD0741  [4]
 LDCM0425  CL36 HCT 116 C665(0.96)  LDD0742  [4]
 LDCM0426  CL37 HCT 116 C665(0.99)  LDD0743  [4]
 LDCM0428  CL39 HCT 116 C665(0.85)  LDD0745  [4]
 LDCM0429  CL4 HCT 116 C665(1.03)  LDD0746  [4]
 LDCM0430  CL40 HCT 116 C665(0.85)  LDD0747  [4]
 LDCM0431  CL41 HCT 116 C665(0.92)  LDD0748  [4]
 LDCM0432  CL42 HCT 116 C665(0.85)  LDD0749  [4]
 LDCM0433  CL43 HCT 116 C665(0.86)  LDD0750  [4]
 LDCM0434  CL44 HCT 116 C665(0.86)  LDD0751  [4]
 LDCM0435  CL45 HCT 116 C665(0.83)  LDD0752  [4]
 LDCM0436  CL46 HEK-293T C186(0.99)  LDD1034  [4]
 LDCM0437  CL47 HEK-293T C186(1.15)  LDD1035  [4]
 LDCM0438  CL48 HEK-293T C186(1.08)  LDD1036  [4]
 LDCM0439  CL49 HEK-293T C186(1.17)  LDD1037  [4]
 LDCM0440  CL5 HCT 116 C665(0.89)  LDD0757  [4]
 LDCM0441  CL50 HEK-293T C186(1.21)  LDD1039  [4]
 LDCM0442  CL51 HEK-293T C186(1.23)  LDD1040  [4]
 LDCM0443  CL52 HEK-293T C186(0.93)  LDD1041  [4]
 LDCM0444  CL53 HEK-293T C186(0.85)  LDD1042  [4]
 LDCM0445  CL54 HEK-293T C186(1.12)  LDD1043  [4]
 LDCM0446  CL55 HEK-293T C186(0.98)  LDD1044  [4]
 LDCM0447  CL56 HEK-293T C186(1.25)  LDD1045  [4]
 LDCM0448  CL57 HEK-293T C186(1.11)  LDD1046  [4]
 LDCM0449  CL58 HEK-293T C186(1.15)  LDD1047  [4]
 LDCM0450  CL59 HEK-293T C186(1.12)  LDD1048  [4]
 LDCM0451  CL6 HCT 116 C665(1.02)  LDD0768  [4]
 LDCM0452  CL60 HEK-293T C186(1.29)  LDD1050  [4]
 LDCM0453  CL61 HEK-293T C186(1.00); C665(0.96)  LDD1051  [4]
 LDCM0454  CL62 HEK-293T C186(1.12); C665(1.11)  LDD1052  [4]
 LDCM0455  CL63 HEK-293T C186(0.85); C665(1.08)  LDD1053  [4]
 LDCM0456  CL64 HEK-293T C186(1.10); C665(1.27)  LDD1054  [4]
 LDCM0457  CL65 HEK-293T C186(0.82); C665(1.14)  LDD1055  [4]
 LDCM0458  CL66 HEK-293T C186(0.90); C665(1.09)  LDD1056  [4]
 LDCM0459  CL67 HEK-293T C186(0.98); C665(1.31)  LDD1057  [4]
 LDCM0460  CL68 HEK-293T C186(1.01); C665(1.27)  LDD1058  [4]
 LDCM0461  CL69 HEK-293T C186(1.23); C665(1.12)  LDD1059  [4]
 LDCM0462  CL7 HCT 116 C665(1.00)  LDD0779  [4]
 LDCM0463  CL70 HEK-293T C186(1.10); C665(1.09)  LDD1061  [4]
 LDCM0464  CL71 HEK-293T C186(1.12); C665(1.22)  LDD1062  [4]
 LDCM0465  CL72 HEK-293T C186(1.11); C665(1.10)  LDD1063  [4]
 LDCM0466  CL73 HEK-293T C186(1.14); C665(1.10)  LDD1064  [4]
 LDCM0467  CL74 HEK-293T C186(1.09); C665(1.03)  LDD1065  [4]
 LDCM0469  CL76 HCT 116 C665(1.10)  LDD0786  [4]
 LDCM0470  CL77 HCT 116 C665(1.07)  LDD0787  [4]
 LDCM0471  CL78 HCT 116 C665(0.96)  LDD0788  [4]
 LDCM0472  CL79 HCT 116 C665(1.23)  LDD0789  [4]
 LDCM0473  CL8 HCT 116 C665(0.82)  LDD0790  [4]
 LDCM0474  CL80 HCT 116 C665(1.07)  LDD0791  [4]
 LDCM0475  CL81 HCT 116 C665(1.11)  LDD0792  [4]
 LDCM0476  CL82 HCT 116 C665(0.93)  LDD0793  [4]
 LDCM0477  CL83 HCT 116 C665(1.09)  LDD0794  [4]
 LDCM0478  CL84 HCT 116 C665(1.12)  LDD0795  [4]
 LDCM0479  CL85 HCT 116 C665(1.31)  LDD0796  [4]
 LDCM0480  CL86 HCT 116 C665(0.98)  LDD0797  [4]
 LDCM0481  CL87 HCT 116 C665(1.03)  LDD0798  [4]
 LDCM0482  CL88 HCT 116 C665(1.10)  LDD0799  [4]
 LDCM0483  CL89 HCT 116 C665(0.97)  LDD0800  [4]
 LDCM0484  CL9 HCT 116 C665(0.83)  LDD0801  [4]
 LDCM0485  CL90 HCT 116 C665(1.17)  LDD0802  [4]
 LDCM0486  CL91 HCT 116 C665(1.02)  LDD0803  [4]
 LDCM0487  CL92 HCT 116 C665(1.31)  LDD0804  [4]
 LDCM0488  CL93 HCT 116 C665(1.20)  LDD0805  [4]
 LDCM0489  CL94 HCT 116 C665(1.41)  LDD0806  [4]
 LDCM0490  CL95 HCT 116 C665(1.29)  LDD0807  [4]
 LDCM0491  CL96 HCT 116 C665(1.03)  LDD0808  [4]
 LDCM0492  CL97 HCT 116 C665(1.19)  LDD0809  [4]
 LDCM0493  CL98 HCT 116 C665(1.27)  LDD0810  [4]
 LDCM0494  CL99 HCT 116 C665(1.11)  LDD0811  [4]
 LDCM0028  Dobutamine HEK-293T 5.85  LDD0180  [2]
 LDCM0495  E2913 HEK-293T C469(1.01)  LDD1698  [10]
 LDCM0576  Fragment14 Ramos C469(0.80)  LDD2193  [11]
 LDCM0468  Fragment33 HEK-293T C186(0.86); C665(1.20)  LDD1066  [4]
 LDCM0427  Fragment51 HCT 116 C665(1.17)  LDD0744  [4]
 LDCM0569  Fragment7 Ramos C469(1.30)  LDD2186  [11]
 LDCM0022  KB02 HCT 116 C665(1.77)  LDD0080  [4]
 LDCM0023  KB03 HCT 116 C665(1.48)  LDD0081  [4]
 LDCM0024  KB05 HCT 116 C665(1.87)  LDD0082  [4]
 LDCM0030  Luteolin HEK-293T 5.51  LDD0182  [2]
 LDCM0032  Oleacein HEK-293T 7.29  LDD0184  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Coiled-coil domain-containing protein 103 (CCDC103) CCDC103/PR46b family Q8IW40

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 A chemical probe unravels the reactive proteome of health-associated catechols. Chem Sci. 2023 Jul 22;14(32):8635-8643. doi: 10.1039/d3sc00888f. eCollection 2023 Aug 16.
Mass spectrometry data entry: PXD043348
3 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
4 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
5 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
6 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
7 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
8 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
9 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
10 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
11 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578