Details of the Target

General Information of Target

Target ID LDTP18116
Target Name PHD finger protein 3 (PHF3)
Gene Name PHF3
Gene ID 23469
Synonyms
KIAA0244; PHD finger protein 3
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGKRAGGGATGATTAAVSTSAGAGLEPAAARSGGPRSAAAGLLGALHLVMTLVVAAARAE
KEAFVQSESIIEVLRFDDGGLLQTETTLGLSSYQQKSISLYRGNCRPIRFEPPMLDFHEQ
PVGMPKMEKVYLHNPSSEETITLVSISATTSHFHASFFQNRKILPGGNTSFDVVFLARVV
GNVENTLFINTSNHGVFTYQVFGVGVPNPYRLRPFLGARVPVNSSFSPIINIHNPHSEPL
QVVEMYSSGGDLHLELPTGQQGGTRKLWEIPPYETKGVMRASFSSREADNHTAFIRIKTN
ASDSTEFIILPVEVEVTTAPGIYSSTEMLDFGTLRTQDLPKVLNLHLLNSGTKDVPITSV
RPTPQNDAITVHFKPITLKASESKYTKVASISFDASKAKKPSQFSGKITVKAKEKSYSKL
EIPYQAEVLDGYLGFDHAATLFHIRDSPADPVERPIYLTNTFSFAILIHDVLLPEEAKTM
FKVHNFSKPVLILPNESGYIFTLLFMPSTSSMHIDNNILLITNASKFHLPVRVYTGFLDY
FVLPPKIEERFIDFGVLSATEASNILFAIINSNPIELAIKSWHIIGDGLSIELVAVERGN
RTTIISSLPEFEKSSLSDQSSVTLASGYFAVFRVKLTAKKLEGIHDGAIQITTDYEILTI
PVKAVIAVGSLTCFPKHVVLPPSFPGKIVHQSLNIMNSFSQKVKIQQIRSLSEDVRFYYK
RLRGNKEDLEPGKKSKIANIYFDPGLQCGDHCYVGLPFLSKSEPKVQPGVAMQEDMWDAD
WDLHQSLFKGWTGIKENSGHRLSAIFEVNTDLQKNIISKITAELSWPSILSSPRHLKFPL
TNTNCSSEEEITLENPADVPVYVQFIPLALYSNPSVFVDKLVSRFNLSKVAKIDLRTLEF
QVFRNSAHPLQSSTGFMEGLSRHLILNLILKPGEKKSVKVKFTPVHNRTVSSLIIVRNNL
TVMDAVMVQGQGTTENLRVAGKLPGPGSSLRFKITEALLKDCTDSLKLREPNFTLKRTFK
VENTGQLQIHIETIEISGYSCEGYGFKVVNCQEFTLSANASRDIIILFTPDFTASRVIRE
LKFITTSGSEFVFILNASLPYHMLATCAEALPRPNWELALYIIISGIMSALFLLVIGTAY
LEAQGIWEPFRRRLSFEASNPPFDVGRPFDLRRIVGISSEGNLNTLSCDPGHSRGFCGAG
GSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRAKNSSSTSSRTSAQAASSQSANKT
SPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHSPLEQHPQPPLPPPVPQPQEPQPER
LSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPKS
KGKGKPLQRKVKPPKKQEEKEKKGKGKPQEDELKDSLADDDSSSTTTETSNPDTEPLLKE
DTEKQKGKQAMPEKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLESKQRRN
LPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQELGNTSSSEGEKDSP
PPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPAAPCPFVARGSY
SSIVNSSSSSDPKIKQPNGSKHKLTKAASLPGKNGNPTFAAVTAGYDKSPGGNGFAKVSS
NKTGFSSSLGISHAPVDSDGSDSSGLWSPVSNPSSPDFTPLNSFSAFGNSFNLTGEVFSK
LGLSRSCNQASQRSWNEFNSGPSYLWESPATDPSPSWPASSGSPTHTATSVLGNTSGLWS
TTPFSSSIWSSNLSSALPFTTPANTLASIGLMGTENSPAPHAPSTSSPADDLGQTYNPWR
IWSPTIGRRSSDPWSNSHFPHEN
Target Bioclass
Other
Uniprot ID
Q92576
Ensemble ID
ENST00000262043.8
HGNC ID
HGNC:8921

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
A3KAW SNV: p.K159R DBIA    Probe Info 
AN3CA Deletion: p.T579HfsTer7 DBIA    Probe Info 
CCK81 Deletion: p.I454_E455del DBIA    Probe Info 
CHL1 SNV: p.D1926Y DBIA    Probe Info 
CORL23 SNV: p.G302C DBIA    Probe Info 
DU145 Deletion: p.V1137Ter DBIA    Probe Info 
EOL1 SNV: p.K513T DBIA    Probe Info 
HCT116 SNV: p.C735Y DBIA    Probe Info 
HCT15 SNV: p.L360I; p.T1781N DBIA    Probe Info 
HEC1B SNV: p.L580S .
HT115 SNV: p.R202Q; p.R673H DBIA    Probe Info 
KARPAS299 SNV: p.K668R DBIA    Probe Info 
KASUMI2 SNV: p.L1239P DBIA    Probe Info 
KYM1 SNV: p.I1261M DBIA    Probe Info 
LNCaP clone FGC Insertion: p.R971SfsTer6 DBIA    Probe Info 
MDST8 SNV: p.R971L DBIA    Probe Info 
MEWO SNV: p.P1776S
Substitution: p.Q446Ter		 DBIA    Probe Info 
MFE296 SNV: p.I1035V DBIA    Probe Info 
NCIH661 SNV: p.P176S IA-alkyne    Probe Info 
NUGC3 SNV: p.P12H DBIA    Probe Info 
RL952 SNV: p.R202Q DBIA    Probe Info 
SKOV3 SNV: p.L1573Ter DBIA    Probe Info 
SNU1 SNV: p.G758D DBIA    Probe Info 
SUPT1 SNV: p.R1891Q DBIA    Probe Info 
SW1573 SNV: p.R737T DBIA    Probe Info 
TOV21G Insertion: p.V1137SfsTer15
SNV: p.R971W		 DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 25 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
STPyne
 Probe Info  		K1002(2.78); K1931(4.91); K936(6.35); K961(10.00)  LDD0277  [2]
BTD
 Probe Info  		C561(0.80)  LDD2099  [3]
Sulforaphane-probe2
 Probe Info  		2.11  LDD0160  [4]
AHL-Pu-1
 Probe Info  		C885(2.06); C441(7.34)  LDD0168  [5]
DBIA
 Probe Info  		C561(1.12); C402(1.11); C1616(1.06); C885(1.05)  LDD0078  [6]
4-Iodoacetamidophenylacetylene
 Probe Info  		C885(0.00); C735(0.00); C1709(0.00); C627(0.00)  LDD0038  [7]
IA-alkyne
 Probe Info  		C186(0.00); C735(0.00); C561(0.00); C276(0.00)  LDD0036  [7]
Lodoacetamide azide
 Probe Info  		C276(0.00); C402(0.00); C1709(0.00); C885(0.00)  LDD0037  [7]
NAIA_4
 Probe Info  		C276(0.00); C402(0.00); C802(0.00); C885(0.00)  LDD2226  [8]
NAIA_5
 Probe Info  		C1631(0.00); C1771(0.00); C276(0.00); C402(0.00)  LDD2224  [8]
TFBX
 Probe Info  		C1771(0.00); C1270(0.00)  LDD0027  [9]
WYneO
 Probe Info  		N.A.  LDD0022  [10]
1d-yne
 Probe Info  		N.A.  LDD0356  [11]
Compound 10
 Probe Info  		C1709(0.00); C561(0.00); C885(0.00)  LDD2216  [12]
Compound 11
 Probe Info  		C1709(0.00); C885(0.00)  LDD2213  [12]
ENE
 Probe Info  		N.A.  LDD0006  [10]
IPM
 Probe Info  		C350(0.00); C1709(0.00); C1702(0.00); C885(0.00)  LDD0005  [10]
VSF
 Probe Info  		C276(0.00); C1709(0.00); C1631(0.00)  LDD0007  [10]
Phosphinate-6
 Probe Info  		C186(0.00); C561(0.00); C1358(0.00); C1771(0.00)  LDD0018  [13]
Acrolein
 Probe Info  		C1709(0.00); C885(0.00)  LDD0217  [14]
Crotonaldehyde
 Probe Info  		N.A.  LDD0219  [14]
Methacrolein
 Probe Info  		C885(0.00); C606(0.00); C1709(0.00)  LDD0218  [14]
W1
 Probe Info  		C402(0.00); C561(0.00); C735(0.00)  LDD0236  [15]
AOyne
 Probe Info  		15.00  LDD0443  [16]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C1270(1.17); C561(0.92)  LDD2117  [3]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C606(1.23)  LDD2152  [3]
 LDCM0025  4SU-RNA HEK-293T C885(2.06); C441(7.34)  LDD0168  [5]
 LDCM0026  4SU-RNA+native RNA HEK-293T C885(2.59); C186(2.33)  LDD0169  [5]
 LDCM0214  AC1 HCT 116 C240(0.76); C255(0.76); C366(1.14); C373(1.14)  LDD0531  [6]
 LDCM0215  AC10 HCT 116 C240(1.07); C255(1.07); C366(0.99); C373(0.99)  LDD0532  [6]
 LDCM0216  AC100 HCT 116 C402(1.46); C738(0.73); C746(0.73)  LDD0533  [6]
 LDCM0217  AC101 HCT 116 C402(1.19); C738(0.89); C746(0.89)  LDD0534  [6]
 LDCM0218  AC102 HCT 116 C402(1.26); C738(0.83); C746(0.83)  LDD0535  [6]
 LDCM0219  AC103 HCT 116 C402(1.39); C738(1.04); C746(1.04)  LDD0536  [6]
 LDCM0220  AC104 HCT 116 C402(1.14); C738(0.85); C746(0.85)  LDD0537  [6]
 LDCM0221  AC105 HCT 116 C402(1.47); C738(1.14); C746(1.14)  LDD0538  [6]
 LDCM0222  AC106 HCT 116 C402(1.54); C738(1.12); C746(1.12)  LDD0539  [6]
 LDCM0223  AC107 HCT 116 C402(1.38); C738(0.81); C746(1.00)  LDD0540  [6]
 LDCM0224  AC108 HCT 116 C402(1.52); C738(0.53); C746(0.63)  LDD0541  [6]
 LDCM0225  AC109 HCT 116 C402(1.14); C738(0.45); C746(0.79)  LDD0542  [6]
 LDCM0226  AC11 HCT 116 C240(1.19); C255(1.19); C366(1.16); C373(1.16)  LDD0543  [6]
 LDCM0227  AC110 HCT 116 C402(1.29); C738(0.62); C746(0.76)  LDD0544  [6]
 LDCM0228  AC111 HCT 116 C402(1.44); C738(0.55); C746(0.74)  LDD0545  [6]
 LDCM0229  AC112 HCT 116 C402(1.38); C738(0.76); C746(0.85)  LDD0546  [6]
 LDCM0230  AC113 HCT 116 C1709(0.79); C240(1.04); C255(0.90); C262(0.76)  LDD0547  [6]
 LDCM0231  AC114 HCT 116 C1709(0.81); C240(1.19); C255(1.21); C262(1.18)  LDD0548  [6]
 LDCM0232  AC115 HCT 116 C1709(0.83); C240(1.50); C255(1.43); C262(0.91)  LDD0549  [6]
 LDCM0233  AC116 HCT 116 C1709(0.93); C240(1.71); C255(1.34); C262(0.98)  LDD0550  [6]
 LDCM0234  AC117 HCT 116 C1709(1.14); C240(1.08); C255(1.19); C262(0.98)  LDD0551  [6]
 LDCM0235  AC118 HCT 116 C1709(1.03); C240(1.00); C255(0.98); C262(0.83)  LDD0552  [6]
 LDCM0236  AC119 HCT 116 C1709(0.87); C240(1.17); C255(0.98); C262(1.34)  LDD0553  [6]
 LDCM0237  AC12 HCT 116 C240(0.96); C255(0.96); C366(1.02); C373(1.02)  LDD0554  [6]
 LDCM0238  AC120 HCT 116 C1709(0.74); C240(1.43); C255(1.35); C262(1.24)  LDD0555  [6]
 LDCM0239  AC121 HCT 116 C1709(1.08); C240(1.07); C255(1.01); C262(0.84)  LDD0556  [6]
 LDCM0240  AC122 HCT 116 C1709(0.85); C240(1.07); C255(1.14); C262(1.20)  LDD0557  [6]
 LDCM0241  AC123 HCT 116 C1709(1.19); C240(0.96); C255(0.96); C262(1.13)  LDD0558  [6]
 LDCM0242  AC124 HCT 116 C1709(0.92); C240(1.02); C255(0.86); C262(1.16)  LDD0559  [6]
 LDCM0243  AC125 HCT 116 C1709(0.92); C240(1.11); C255(1.32); C262(1.09)  LDD0560  [6]
 LDCM0244  AC126 HCT 116 C1709(0.88); C240(1.73); C255(1.37); C262(0.77)  LDD0561  [6]
 LDCM0245  AC127 HCT 116 C1709(0.84); C240(1.48); C255(1.12); C262(0.76)  LDD0562  [6]
 LDCM0246  AC128 HCT 116 C240(1.09); C255(1.30); C262(0.86); C561(0.55)  LDD0563  [6]
 LDCM0247  AC129 HCT 116 C240(1.00); C255(1.18); C262(0.70); C561(0.63)  LDD0564  [6]
 LDCM0249  AC130 HCT 116 C240(0.92); C255(0.99); C262(0.79); C561(0.68)  LDD0566  [6]
 LDCM0250  AC131 HCT 116 C240(1.03); C255(1.19); C262(0.79); C561(0.73)  LDD0567  [6]
 LDCM0251  AC132 HCT 116 C240(0.71); C255(0.70); C262(0.57); C561(0.77)  LDD0568  [6]
 LDCM0252  AC133 HCT 116 C240(0.83); C255(0.91); C262(0.71); C561(0.63)  LDD0569  [6]
 LDCM0253  AC134 HCT 116 C240(0.98); C255(1.03); C262(0.85); C561(0.69)  LDD0570  [6]
 LDCM0254  AC135 HCT 116 C240(0.74); C255(0.74); C262(0.62); C561(0.76)  LDD0571  [6]
 LDCM0255  AC136 HCT 116 C240(0.88); C255(0.86); C262(0.76); C561(0.64)  LDD0572  [6]
 LDCM0256  AC137 HCT 116 C240(0.80); C255(0.87); C262(0.73); C561(0.69)  LDD0573  [6]
 LDCM0257  AC138 HCT 116 C240(0.76); C255(0.73); C262(0.70); C561(0.90)  LDD0574  [6]
 LDCM0258  AC139 HCT 116 C240(0.85); C255(0.83); C262(0.80); C561(1.00)  LDD0575  [6]
 LDCM0259  AC14 HCT 116 C240(0.85); C255(0.85); C366(1.04); C373(1.04)  LDD0576  [6]
 LDCM0260  AC140 HCT 116 C240(0.92); C255(0.95); C262(0.77); C561(0.98)  LDD0577  [6]
 LDCM0261  AC141 HCT 116 C240(0.94); C255(0.90); C262(0.85); C561(0.85)  LDD0578  [6]
 LDCM0262  AC142 HCT 116 C240(0.73); C255(0.68); C262(0.74); C561(0.72)  LDD0579  [6]
 LDCM0263  AC143 HCT 116 C262(0.85); C735(0.96); C240(0.98); C255(0.98)  LDD0580  [6]
 LDCM0264  AC144 HCT 116 C735(1.18); C262(1.25); C1709(1.45); C240(1.48)  LDD0581  [6]
 LDCM0265  AC145 HCT 116 C262(1.07); C735(1.09); C1709(1.12); C240(1.16)  LDD0582  [6]
 LDCM0266  AC146 HCT 116 C735(0.95); C262(1.19); C240(1.27); C255(1.27)  LDD0583  [6]
 LDCM0267  AC147 HCT 116 C735(0.93); C262(1.15); C1709(1.25); C240(1.33)  LDD0584  [6]
 LDCM0268  AC148 HCT 116 C735(1.02); C262(1.37); C1709(1.63); C240(1.77)  LDD0585  [6]
 LDCM0269  AC149 HCT 116 C735(0.83); C262(1.23); C240(1.54); C255(1.54)  LDD0586  [6]
 LDCM0270  AC15 HCT 116 C738(0.96); C746(0.96); C402(1.05); C240(1.22)  LDD0587  [6]
 LDCM0271  AC150 HCT 116 C262(0.79); C240(0.95); C255(0.95); C735(1.01)  LDD0588  [6]
 LDCM0272  AC151 HCT 116 C735(1.05); C262(1.14); C240(1.19); C255(1.19)  LDD0589  [6]
 LDCM0273  AC152 HCT 116 C735(0.94); C738(1.20); C746(1.20); C262(1.26)  LDD0590  [6]
 LDCM0274  AC153 HCT 116 C735(1.26); C262(1.65); C738(1.91); C746(1.91)  LDD0591  [6]
 LDCM0621  AC154 HCT 116 C1709(1.61); C240(1.40); C255(1.40); C262(1.20)  LDD2158  [6]
 LDCM0622  AC155 HCT 116 C1709(1.75); C240(1.55); C255(1.55); C262(1.33)  LDD2159  [6]
 LDCM0623  AC156 HCT 116 C1709(1.42); C240(1.24); C255(1.24); C262(1.03)  LDD2160  [6]
 LDCM0624  AC157 HCT 116 C1709(1.57); C240(1.61); C255(1.61); C262(1.47)  LDD2161  [6]
 LDCM0276  AC17 HCT 116 C1709(0.57); C561(0.81); C402(0.91); C738(1.03)  LDD0593  [6]
 LDCM0277  AC18 HCT 116 C1709(0.69); C561(0.92); C738(1.01); C746(1.01)  LDD0594  [6]
 LDCM0278  AC19 HCT 116 C1709(0.61); C561(0.76); C402(1.11); C240(1.38)  LDD0595  [6]
 LDCM0279  AC2 HCT 116 C561(0.79); C240(0.92); C255(0.92); C735(0.93)  LDD0596  [6]
 LDCM0280  AC20 HCT 116 C1709(0.64); C402(1.05); C738(1.19); C746(1.19)  LDD0597  [6]
 LDCM0281  AC21 HCT 116 C1709(0.47); C561(0.74); C402(1.22); C738(1.41)  LDD0598  [6]
 LDCM0282  AC22 HCT 116 C1709(0.48); C240(1.07); C255(1.07); C402(1.13)  LDD0599  [6]
 LDCM0283  AC23 HCT 116 C1709(0.44); C561(0.73); C402(0.93); C738(1.11)  LDD0600  [6]
 LDCM0284  AC24 HCT 116 C1709(0.48); C402(1.06); C738(1.16); C746(1.16)  LDD0601  [6]
 LDCM0285  AC25 HCT 116 C240(1.01); C255(1.01)  LDD0602  [6]
 LDCM0286  AC26 HCT 116 C240(1.12); C255(1.12)  LDD0603  [6]
 LDCM0287  AC27 HCT 116 C240(1.25); C255(1.25)  LDD0604  [6]
 LDCM0288  AC28 HCT 116 C240(1.27); C255(1.27)  LDD0605  [6]
 LDCM0289  AC29 HCT 116 C240(1.19); C255(1.19)  LDD0606  [6]
 LDCM0290  AC3 HCT 116 C240(0.75); C255(0.75); C561(0.94); C735(1.07)  LDD0607  [6]
 LDCM0291  AC30 HCT 116 C240(1.29); C255(1.29)  LDD0608  [6]
 LDCM0292  AC31 HCT 116 C240(1.21); C255(1.21)  LDD0609  [6]
 LDCM0293  AC32 HCT 116 C240(1.30); C255(1.30)  LDD0610  [6]
 LDCM0294  AC33 HCT 116 C240(1.32); C255(1.32)  LDD0611  [6]
 LDCM0295  AC34 HCT 116 C240(1.45); C255(1.45)  LDD0612  [6]
 LDCM0296  AC35 HCT 116 C738(0.68); C746(0.68); C561(0.73); C240(0.91)  LDD0613  [6]
 LDCM0297  AC36 HCT 116 C240(0.85); C255(0.85); C738(0.87); C746(0.87)  LDD0614  [6]
 LDCM0298  AC37 HCT 116 C561(0.52); C402(0.80); C240(0.83); C255(0.83)  LDD0615  [6]
 LDCM0299  AC38 HCT 116 C561(0.56); C240(0.97); C255(0.97); C738(1.00)  LDD0616  [6]
 LDCM0300  AC39 HCT 116 C561(0.64); C240(0.98); C255(0.98); C738(1.07)  LDD0617  [6]
 LDCM0301  AC4 HCT 116 C561(0.56); C240(0.67); C255(0.67); C735(1.04)  LDD0618  [6]
 LDCM0302  AC40 HCT 116 C561(0.96); C402(1.05); C240(1.08); C255(1.08)  LDD0619  [6]
 LDCM0303  AC41 HCT 116 C561(0.67); C240(0.71); C255(0.71); C738(0.82)  LDD0620  [6]
 LDCM0304  AC42 HCT 116 C561(0.76); C240(0.83); C255(0.83); C738(0.91)  LDD0621  [6]
 LDCM0305  AC43 HCT 116 C240(0.80); C255(0.80); C561(0.88); C738(0.89)  LDD0622  [6]
 LDCM0306  AC44 HCT 116 C240(0.65); C255(0.65); C402(0.93); C738(1.03)  LDD0623  [6]
 LDCM0307  AC45 HCT 116 C402(0.85); C561(0.89); C240(1.13); C255(1.13)  LDD0624  [6]
 LDCM0308  AC46 HCT 116 C240(0.68); C255(0.68); C402(1.37)  LDD0625  [6]
 LDCM0309  AC47 HCT 116 C240(0.71); C255(0.71); C402(0.98)  LDD0626  [6]
 LDCM0310  AC48 HCT 116 C240(0.74); C255(0.74); C402(1.07)  LDD0627  [6]
 LDCM0311  AC49 HCT 116 C240(1.08); C255(1.08); C402(1.18)  LDD0628  [6]
 LDCM0312  AC5 HCT 116 C561(0.41); C240(0.67); C255(0.67); C735(0.83)  LDD0629  [6]
 LDCM0313  AC50 HCT 116 C240(0.75); C255(0.75); C402(1.11)  LDD0630  [6]
 LDCM0314  AC51 HCT 116 C240(0.89); C255(0.89); C402(0.96)  LDD0631  [6]
 LDCM0315  AC52 HCT 116 C240(0.90); C255(0.90); C402(1.10)  LDD0632  [6]
 LDCM0316  AC53 HCT 116 C240(0.73); C255(0.73); C402(0.79)  LDD0633  [6]
 LDCM0317  AC54 HCT 116 C240(0.83); C255(0.83); C402(0.98)  LDD0634  [6]
 LDCM0318  AC55 HCT 116 C240(0.70); C255(0.70); C402(0.85)  LDD0635  [6]
 LDCM0319  AC56 HCT 116 C240(0.77); C255(0.77); C402(0.93)  LDD0636  [6]
 LDCM0320  AC57 HCT 116 C240(0.74); C255(0.74); C402(0.83); C769(1.59)  LDD0637  [6]
 LDCM0321  AC58 HCT 116 C240(0.62); C255(0.62); C402(0.80); C769(1.51)  LDD0638  [6]
 LDCM0322  AC59 HCT 116 C240(0.57); C255(0.57); C402(0.85); C769(1.47)  LDD0639  [6]
 LDCM0323  AC6 HCT 116 C240(1.04); C255(1.04); C402(1.05); C366(1.25)  LDD0640  [6]
 LDCM0324  AC60 HCT 116 C240(0.64); C255(0.64); C402(1.00); C769(1.58)  LDD0641  [6]
 LDCM0325  AC61 HCT 116 C402(0.77); C240(0.79); C255(0.79); C769(1.29)  LDD0642  [6]
 LDCM0326  AC62 HCT 116 C240(0.61); C255(0.61); C402(0.85); C561(1.81)  LDD0643  [6]
 LDCM0327  AC63 HCT 116 C240(0.57); C255(0.57); C402(0.81); C769(1.33)  LDD0644  [6]
 LDCM0328  AC64 HCT 116 C240(0.53); C255(0.53); C402(0.79); C769(1.53)  LDD0645  [6]
 LDCM0329  AC65 HCT 116 C240(0.80); C255(0.80); C402(0.88); C769(0.99)  LDD0646  [6]
 LDCM0330  AC66 HCT 116 C402(0.79); C240(0.79); C255(0.79); C769(0.86)  LDD0647  [6]
 LDCM0331  AC67 HCT 116 C240(0.58); C255(0.58); C769(0.84); C770(0.84)  LDD0648  [6]
 LDCM0332  AC68 HCT 116 C561(0.88); C402(0.92); C240(0.93); C255(0.93)  LDD0649  [6]
 LDCM0333  AC69 HCT 116 C561(0.65); C240(0.86); C255(0.86); C402(0.90)  LDD0650  [6]
 LDCM0334  AC7 HCT 116 C240(0.74); C255(0.74); C366(0.78); C373(0.78)  LDD0651  [6]
 LDCM0335  AC70 HCT 116 C561(0.78); C402(0.99); C240(0.99); C255(0.99)  LDD0652  [6]
 LDCM0336  AC71 HCT 116 C240(0.77); C255(0.77); C769(0.79); C770(0.79)  LDD0653  [6]
 LDCM0337  AC72 HCT 116 C240(0.91); C255(0.91); C561(0.98); C769(1.01)  LDD0654  [6]
 LDCM0338  AC73 HCT 116 C366(0.94); C373(0.94); C561(1.01); C402(1.10)  LDD0655  [6]
 LDCM0339  AC74 HCT 116 C366(0.82); C373(0.82); C561(0.91); C402(0.97)  LDD0656  [6]
 LDCM0340  AC75 HCT 116 C561(0.82); C402(1.11); C240(1.30); C255(1.30)  LDD0657  [6]
 LDCM0341  AC76 HCT 116 C561(0.85); C402(0.93); C240(0.97); C255(0.97)  LDD0658  [6]
 LDCM0342  AC77 HCT 116 C561(0.87); C402(0.93); C366(0.95); C373(0.95)  LDD0659  [6]
 LDCM0343  AC78 HCT 116 C561(0.86); C240(0.87); C255(0.87); C769(0.98)  LDD0660  [6]
 LDCM0344  AC79 HCT 116 C561(0.76); C769(0.78); C770(0.78); C738(0.89)  LDD0661  [6]
 LDCM0345  AC8 HCT 116 C738(0.72); C746(0.72); C366(0.92); C373(0.92)  LDD0662  [6]
 LDCM0346  AC80 HCT 116 C561(0.94); C402(1.02); C240(1.03); C255(1.03)  LDD0663  [6]
 LDCM0347  AC81 HCT 116 C738(0.72); C746(0.72); C769(0.73); C770(0.73)  LDD0664  [6]
 LDCM0348  AC82 HCT 116 C561(0.79); C402(0.97); C366(1.16); C373(1.16)  LDD0665  [6]
 LDCM0349  AC83 HCT 116 C738(1.12); C746(1.12); C402(1.18); C1709(1.39)  LDD0666  [6]
 LDCM0350  AC84 HCT 116 C1709(1.02); C738(1.10); C746(1.10); C402(1.23)  LDD0667  [6]
 LDCM0351  AC85 HCT 116 C1709(0.91); C240(1.17); C255(1.17); C402(1.20)  LDD0668  [6]
 LDCM0352  AC86 HCT 116 C1709(1.17); C240(1.23); C255(1.23); C738(1.27)  LDD0669  [6]
 LDCM0353  AC87 HCT 116 C1709(0.92); C738(0.97); C746(0.97); C402(1.16)  LDD0670  [6]
 LDCM0354  AC88 HCT 116 C738(0.97); C746(0.97); C1709(1.17); C402(1.29)  LDD0671  [6]
 LDCM0355  AC89 HCT 116 C738(1.17); C746(1.17); C1709(1.26); C402(1.32)  LDD0672  [6]
 LDCM0357  AC90 HCT 116 C240(1.11); C255(1.11); C738(1.20); C746(1.20)  LDD0674  [6]
 LDCM0358  AC91 HCT 116 C1709(1.08); C402(1.13); C738(1.28); C746(1.28)  LDD0675  [6]
 LDCM0359  AC92 HCT 116 C1709(1.06); C402(1.11); C738(1.28); C746(1.28)  LDD0676  [6]
 LDCM0360  AC93 HCT 116 C1709(1.00); C738(1.03); C746(1.03); C402(1.18)  LDD0677  [6]
 LDCM0361  AC94 HCT 116 C1709(0.69); C769(1.09); C770(1.09); C402(1.21)  LDD0678  [6]
 LDCM0362  AC95 HCT 116 C1709(1.06); C738(1.15); C746(1.15); C402(1.37)  LDD0679  [6]
 LDCM0363  AC96 HCT 116 C1709(0.72); C402(1.17); C738(1.36); C746(1.36)  LDD0680  [6]
 LDCM0364  AC97 HCT 116 C1709(1.16); C769(1.28); C770(1.28); C738(1.49)  LDD0681  [6]
 LDCM0365  AC98 HCT 116 C738(1.33); C746(1.33); C402(1.43)  LDD0682  [6]
 LDCM0366  AC99 HCT 116 C738(0.61); C746(0.61); C402(1.36)  LDD0683  [6]
 LDCM0248  AKOS034007472 HCT 116 C240(1.08); C255(1.08); C366(1.30); C373(1.30)  LDD0565  [6]
 LDCM0356  AKOS034007680 HCT 116 C402(0.87); C240(0.88); C255(0.88); C738(0.93)  LDD0673  [6]
 LDCM0275  AKOS034007705 HCT 116 C735(1.34); C402(1.41); C366(1.59); C373(1.59)  LDD0592  [6]
 LDCM0156  Aniline NCI-H1299 11.61  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C561(1.12); C402(1.11); C1616(1.06); C885(1.05)  LDD0078  [6]
 LDCM0108  Chloroacetamide HeLa C1709(0.00); C885(0.00)  LDD0222  [14]
 LDCM0632  CL-Sc Hep-G2 C627(0.90); C843(0.58)  LDD2227  [8]
 LDCM0367  CL1 HCT 116 C735(0.73); C366(0.73); C373(0.73); C561(0.80)  LDD0684  [6]
 LDCM0368  CL10 HCT 116 C561(0.75); C1709(0.93); C735(0.94); C402(0.99)  LDD0685  [6]
 LDCM0369  CL100 HCT 116 C561(0.51); C240(0.73); C255(0.73); C735(0.98)  LDD0686  [6]
 LDCM0370  CL101 HCT 116 C240(1.02); C255(1.02); C402(1.05); C738(1.31)  LDD0687  [6]
 LDCM0371  CL102 HCT 116 C366(0.92); C373(0.92); C240(0.99); C255(0.99)  LDD0688  [6]
 LDCM0372  CL103 HCT 116 C366(0.79); C373(0.79); C402(0.95); C738(1.07)  LDD0689  [6]
 LDCM0373  CL104 HCT 116 C240(0.93); C255(0.93); C402(0.96); C738(1.08)  LDD0690  [6]
 LDCM0374  CL105 HCT 116 C1709(0.49); C561(0.72); C402(0.94); C240(1.20)  LDD0691  [6]
 LDCM0375  CL106 HCT 116 C1709(0.48); C561(0.52); C402(1.19); C240(1.42)  LDD0692  [6]
 LDCM0376  CL107 HCT 116 C1709(0.56); C561(0.66); C402(1.28); C240(1.32)  LDD0693  [6]
 LDCM0377  CL108 HCT 116 C1709(0.43); C561(0.61); C402(1.11); C738(1.19)  LDD0694  [6]
 LDCM0378  CL109 HCT 116 C1709(0.67); C402(0.99); C561(1.00); C738(1.45)  LDD0695  [6]
 LDCM0379  CL11 HCT 116 C561(0.71); C1709(0.79); C402(0.88); C735(0.95)  LDD0696  [6]
 LDCM0380  CL110 HCT 116 C1709(0.41); C561(0.69); C402(1.10); C738(1.55)  LDD0697  [6]
 LDCM0381  CL111 HCT 116 C1709(0.47); C561(0.80); C402(1.04); C738(1.05)  LDD0698  [6]
 LDCM0382  CL112 HCT 116 C240(1.44); C255(1.44)  LDD0699  [6]
 LDCM0383  CL113 HCT 116 C240(1.46); C255(1.46)  LDD0700  [6]
 LDCM0384  CL114 HCT 116 C240(1.38); C255(1.38)  LDD0701  [6]
 LDCM0385  CL115 HCT 116 C240(1.31); C255(1.31)  LDD0702  [6]
 LDCM0386  CL116 HCT 116 C240(0.99); C255(0.99)  LDD0703  [6]
 LDCM0387  CL117 HCT 116 C402(1.14); C561(1.20); C240(1.42); C255(1.42)  LDD0704  [6]
 LDCM0388  CL118 HCT 116 C240(0.89); C255(0.89); C561(1.01); C738(1.09)  LDD0705  [6]
 LDCM0389  CL119 HCT 116 C561(0.69); C240(0.87); C255(0.87); C738(0.90)  LDD0706  [6]
 LDCM0390  CL12 HCT 116 C735(0.96); C561(0.99); C1709(1.04); C402(1.05)  LDD0707  [6]
 LDCM0391  CL120 HCT 116 C240(0.73); C255(0.73); C561(0.92); C738(1.04)  LDD0708  [6]
 LDCM0392  CL121 HCT 116 C240(0.78); C255(0.78); C402(1.03)  LDD0709  [6]
 LDCM0393  CL122 HCT 116 C402(0.81); C240(0.93); C255(0.93)  LDD0710  [6]
 LDCM0394  CL123 HCT 116 C240(0.65); C255(0.65); C402(0.70)  LDD0711  [6]
 LDCM0395  CL124 HCT 116 C240(0.84); C255(0.84); C402(0.89)  LDD0712  [6]
 LDCM0396  CL125 HCT 116 C240(0.71); C255(0.71); C402(0.95); C561(0.99)  LDD0713  [6]
 LDCM0397  CL126 HCT 116 C240(0.52); C255(0.52); C402(0.81); C769(1.09)  LDD0714  [6]
 LDCM0398  CL127 HCT 116 C240(0.58); C255(0.58); C402(0.92); C561(1.18)  LDD0715  [6]
 LDCM0399  CL128 HCT 116 C240(0.61); C255(0.61); C402(0.77); C769(1.84)  LDD0716  [6]
 LDCM0400  CL13 HCT 116 C402(0.79); C561(0.83); C1709(0.85); C735(0.85)  LDD0717  [6]
 LDCM0401  CL14 HCT 116 C735(0.73); C402(0.92); C1709(1.00); C561(1.04)  LDD0718  [6]
 LDCM0402  CL15 HCT 116 C561(0.64); C402(0.69); C735(0.74); C1709(0.86)  LDD0719  [6]
 LDCM0403  CL16 HCT 116 C366(0.94); C373(0.94); C561(1.04); C402(1.06)  LDD0720  [6]
 LDCM0404  CL17 HCT 116 C366(0.91); C373(0.91); C769(0.95); C770(0.95)  LDD0721  [6]
 LDCM0405  CL18 HCT 116 C769(0.83); C770(0.83); C402(1.04); C1709(1.29)  LDD0722  [6]
 LDCM0406  CL19 HCT 116 C769(1.06); C770(1.06); C402(1.19); C561(1.30)  LDD0723  [6]
 LDCM0407  CL2 HCT 116 C561(0.72); C366(0.86); C373(0.86); C402(0.90)  LDD0724  [6]
 LDCM0408  CL20 HCT 116 C769(0.95); C770(0.95); C366(1.26); C373(1.26)  LDD0725  [6]
 LDCM0409  CL21 HCT 116 C769(0.78); C770(0.78); C402(1.12); C561(1.57)  LDD0726  [6]
 LDCM0410  CL22 HCT 116 C402(0.93); C769(1.26); C770(1.26); C1709(2.42)  LDD0727  [6]
 LDCM0411  CL23 HCT 116 C402(1.09); C769(1.13); C770(1.13); C366(1.26)  LDD0728  [6]
 LDCM0412  CL24 HCT 116 C402(1.02); C769(1.08); C770(1.08); C1709(1.79)  LDD0729  [6]
 LDCM0413  CL25 HCT 116 C1709(1.63); C366(1.40); C373(1.40); C402(0.96)  LDD0730  [6]
 LDCM0414  CL26 HCT 116 C1709(1.34); C366(1.35); C373(1.35); C402(0.94)  LDD0731  [6]
 LDCM0415  CL27 HCT 116 C1709(1.82); C366(1.17); C373(1.17); C402(1.03)  LDD0732  [6]
 LDCM0416  CL28 HCT 116 C1709(1.41); C366(1.14); C373(1.14); C402(1.19)  LDD0733  [6]
 LDCM0417  CL29 HCT 116 C1709(1.70); C366(1.49); C373(1.49); C402(1.46)  LDD0734  [6]
 LDCM0418  CL3 HCT 116 C1709(1.06); C240(1.02); C255(1.02); C366(0.83)  LDD0735  [6]
 LDCM0419  CL30 HCT 116 C1709(1.23); C366(1.25); C373(1.25); C402(1.16)  LDD0736  [6]
 LDCM0420  CL31 HCT 116 C1709(0.76); C240(0.73); C255(0.73); C402(1.05)  LDD0737  [6]
 LDCM0421  CL32 HCT 116 C1709(0.81); C240(0.75); C255(0.75); C402(0.90)  LDD0738  [6]
 LDCM0422  CL33 HCT 116 C1709(0.92); C240(0.81); C255(0.81); C402(0.85)  LDD0739  [6]
 LDCM0423  CL34 HCT 116 C1709(1.30); C240(0.86); C255(0.86); C402(0.75)  LDD0740  [6]
 LDCM0424  CL35 HCT 116 C1709(0.93); C240(0.95); C255(0.95); C402(0.83)  LDD0741  [6]
 LDCM0425  CL36 HCT 116 C1709(0.98); C240(1.11); C255(1.11); C402(0.67)  LDD0742  [6]
 LDCM0426  CL37 HCT 116 C1709(1.00); C240(0.91); C255(0.91); C402(0.83)  LDD0743  [6]
 LDCM0428  CL39 HCT 116 C1709(0.97); C240(0.93); C255(0.93); C402(0.99)  LDD0745  [6]
 LDCM0429  CL4 HCT 116 C1709(0.91); C240(1.19); C255(1.19); C366(0.93)  LDD0746  [6]
 LDCM0430  CL40 HCT 116 C1709(0.74); C240(0.73); C255(0.73); C402(0.78)  LDD0747  [6]
 LDCM0431  CL41 HCT 116 C1709(1.21); C240(1.33); C255(1.33); C402(0.83)  LDD0748  [6]
 LDCM0432  CL42 HCT 116 C1709(0.78); C240(0.79); C255(0.79); C402(0.73)  LDD0749  [6]
 LDCM0433  CL43 HCT 116 C1709(0.87); C240(0.86); C255(0.86); C402(0.87)  LDD0750  [6]
 LDCM0434  CL44 HCT 116 C1709(0.83); C240(0.80); C255(0.80); C402(0.77)  LDD0751  [6]
 LDCM0435  CL45 HCT 116 C1709(1.04); C240(0.67); C255(0.67); C402(0.72)  LDD0752  [6]
 LDCM0436  CL46 HCT 116 C240(1.06); C262(1.06); C402(1.22); C561(0.95)  LDD0753  [6]
 LDCM0437  CL47 HCT 116 C240(0.97); C262(0.97); C402(1.08); C561(0.75)  LDD0754  [6]
 LDCM0438  CL48 HCT 116 C240(1.18); C262(1.18); C402(1.02); C561(0.94)  LDD0755  [6]
 LDCM0439  CL49 HCT 116 C240(0.92); C262(0.92); C402(1.00); C561(1.47)  LDD0756  [6]
 LDCM0440  CL5 HCT 116 C1709(1.03); C240(1.18); C255(1.18); C366(1.17)  LDD0757  [6]
 LDCM0441  CL50 HCT 116 C240(1.09); C262(1.09); C402(0.95); C561(1.49)  LDD0758  [6]
 LDCM0442  CL51 HCT 116 C240(1.16); C262(1.16); C402(1.10); C561(1.01)  LDD0759  [6]
 LDCM0443  CL52 HCT 116 C240(1.25); C262(1.25); C402(1.10); C561(1.00)  LDD0760  [6]
 LDCM0444  CL53 HCT 116 C240(1.00); C262(1.00); C402(0.94); C561(1.15)  LDD0761  [6]
 LDCM0445  CL54 HCT 116 C240(0.92); C262(0.92); C402(0.96); C561(0.87)  LDD0762  [6]
 LDCM0446  CL55 HCT 116 C240(1.04); C262(1.04); C402(1.06); C561(1.11)  LDD0763  [6]
 LDCM0447  CL56 HCT 116 C240(1.03); C262(1.03); C402(1.03); C561(1.04)  LDD0764  [6]
 LDCM0448  CL57 HCT 116 C240(0.99); C262(0.99); C402(0.96); C561(1.16)  LDD0765  [6]
 LDCM0449  CL58 HCT 116 C240(1.02); C262(1.02); C402(1.12); C561(0.92)  LDD0766  [6]
 LDCM0450  CL59 HCT 116 C240(0.92); C262(0.92); C402(1.04); C561(1.19)  LDD0767  [6]
 LDCM0451  CL6 HCT 116 C1709(1.14); C240(1.20); C255(1.20); C366(0.85)  LDD0768  [6]
 LDCM0452  CL60 HCT 116 C240(0.92); C262(0.92); C402(1.07); C561(1.25)  LDD0769  [6]
 LDCM0453  CL61 HCT 116 C240(0.70); C255(0.75); C262(0.81); C366(1.07)  LDD0770  [6]
 LDCM0454  CL62 HCT 116 C240(0.64); C255(0.74); C262(0.83); C366(0.85)  LDD0771  [6]
 LDCM0455  CL63 HCT 116 C240(0.71); C255(0.74); C262(0.78); C366(1.52)  LDD0772  [6]
 LDCM0456  CL64 HCT 116 C240(0.78); C255(0.85); C262(0.92); C366(1.19)  LDD0773  [6]
 LDCM0457  CL65 HCT 116 C240(0.69); C255(0.73); C262(0.78); C366(0.98)  LDD0774  [6]
 LDCM0458  CL66 HCT 116 C240(0.63); C255(0.69); C262(0.75); C366(1.17)  LDD0775  [6]
 LDCM0459  CL67 HCT 116 C240(0.78); C255(0.84); C262(0.90); C366(1.20)  LDD0776  [6]
 LDCM0460  CL68 HCT 116 C240(0.75); C255(0.77); C262(0.80); C366(0.95)  LDD0777  [6]
 LDCM0461  CL69 HCT 116 C240(0.70); C255(0.71); C262(0.73); C366(0.85)  LDD0778  [6]
 LDCM0462  CL7 HCT 116 C1709(0.84); C240(1.13); C255(1.13); C366(1.12)  LDD0779  [6]
 LDCM0463  CL70 HCT 116 C240(0.81); C255(0.83); C262(0.84); C366(1.04)  LDD0780  [6]
 LDCM0464  CL71 HCT 116 C240(0.84); C255(0.90); C262(0.95); C366(1.35)  LDD0781  [6]
 LDCM0465  CL72 HCT 116 C240(1.13); C255(1.11); C262(1.09); C366(1.13)  LDD0782  [6]
 LDCM0466  CL73 HCT 116 C240(0.76); C255(0.89); C262(1.03); C366(1.04)  LDD0783  [6]
 LDCM0467  CL74 HCT 116 C240(0.89); C255(1.00); C262(1.10); C366(1.42)  LDD0784  [6]
 LDCM0469  CL76 HCT 116 C1709(0.71); C240(1.00); C255(1.00); C402(1.02)  LDD0786  [6]
 LDCM0470  CL77 HCT 116 C1709(0.76); C240(0.93); C255(0.93); C402(0.95)  LDD0787  [6]
 LDCM0471  CL78 HCT 116 C1709(1.01); C240(0.88); C255(0.88); C402(0.99)  LDD0788  [6]
 LDCM0472  CL79 HCT 116 C1709(1.00); C240(1.02); C255(1.02); C402(1.05)  LDD0789  [6]
 LDCM0473  CL8 HCT 116 C1709(0.95); C240(1.00); C255(1.00); C366(1.07)  LDD0790  [6]
 LDCM0474  CL80 HCT 116 C1709(0.86); C240(0.71); C255(0.71); C402(0.90)  LDD0791  [6]
 LDCM0475  CL81 HCT 116 C1709(0.90); C240(0.98); C255(0.98); C402(0.99)  LDD0792  [6]
 LDCM0476  CL82 HCT 116 C1709(0.77); C240(0.74); C255(0.74); C402(0.92)  LDD0793  [6]
 LDCM0477  CL83 HCT 116 C1709(0.97); C240(0.65); C255(0.65); C402(1.03)  LDD0794  [6]
 LDCM0478  CL84 HCT 116 C1709(0.95); C240(0.95); C255(0.95); C402(1.08)  LDD0795  [6]
 LDCM0479  CL85 HCT 116 C1709(0.93); C240(0.87); C255(0.87); C402(1.23)  LDD0796  [6]
 LDCM0480  CL86 HCT 116 C1709(0.87); C240(0.64); C255(0.64); C402(1.02)  LDD0797  [6]
 LDCM0481  CL87 HCT 116 C1709(0.76); C240(0.64); C255(0.64); C402(1.25)  LDD0798  [6]
 LDCM0482  CL88 HCT 116 C1709(0.88); C240(0.76); C255(0.76); C402(1.09)  LDD0799  [6]
 LDCM0483  CL89 HCT 116 C1709(1.05); C240(0.75); C255(0.75); C402(0.95)  LDD0800  [6]
 LDCM0484  CL9 HCT 116 C1709(0.90); C240(0.89); C255(0.89); C366(0.96)  LDD0801  [6]
 LDCM0485  CL90 HCT 116 C1709(0.68); C240(0.69); C255(0.69); C402(0.87)  LDD0802  [6]
 LDCM0486  CL91 HCT 116 C240(1.10); C255(1.10); C366(1.18); C373(1.18)  LDD0803  [6]
 LDCM0487  CL92 HCT 116 C240(1.38); C255(1.38); C366(1.03); C373(1.03)  LDD0804  [6]
 LDCM0488  CL93 HCT 116 C240(1.14); C255(1.14); C366(0.97); C373(0.97)  LDD0805  [6]
 LDCM0489  CL94 HCT 116 C240(1.14); C255(1.14); C366(1.39); C373(1.39)  LDD0806  [6]
 LDCM0490  CL95 HCT 116 C240(1.02); C255(1.02); C366(1.15); C373(1.15)  LDD0807  [6]
 LDCM0491  CL96 HCT 116 C240(1.08); C255(1.08); C366(1.75); C373(1.75)  LDD0808  [6]
 LDCM0492  CL97 HCT 116 C240(0.99); C255(0.99); C366(1.17); C373(1.17)  LDD0809  [6]
 LDCM0493  CL98 HCT 116 C240(0.88); C255(0.88); C366(1.12); C373(1.12)  LDD0810  [6]
 LDCM0494  CL99 HCT 116 C240(0.85); C255(0.85); C366(1.15); C373(1.15)  LDD0811  [6]
 LDCM0495  E2913 HEK-293T C606(1.06); C627(1.37); C885(0.91); C1709(0.98)  LDD1698  [17]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C561(1.11); C606(1.06); C1771(0.97)  LDD1702  [3]
 LDCM0625  F8 Ramos C885(1.36)  LDD2187  [18]
 LDCM0572  Fragment10 Ramos C885(1.73)  LDD2189  [18]
 LDCM0573  Fragment11 Ramos C885(15.73); C1673(20.00)  LDD2190  [18]
 LDCM0574  Fragment12 Ramos C885(0.65); C1673(0.76)  LDD2191  [18]
 LDCM0575  Fragment13 Ramos C885(0.97); C402(1.70); C1673(0.75)  LDD2192  [18]
 LDCM0576  Fragment14 Ramos C885(0.93); C1673(0.97)  LDD2193  [18]
 LDCM0579  Fragment20 Ramos C885(0.60)  LDD2194  [18]
 LDCM0580  Fragment21 Ramos C885(0.99); C402(1.52); C1673(0.93)  LDD2195  [18]
 LDCM0582  Fragment23 Ramos C885(0.56); C1673(1.35)  LDD2196  [18]
 LDCM0578  Fragment27 Ramos C885(0.96); C402(1.48); C1673(1.00)  LDD2197  [18]
 LDCM0586  Fragment28 Ramos C885(1.36); C1673(2.43)  LDD2198  [18]
 LDCM0588  Fragment30 Ramos C885(1.12); C402(1.60); C1673(1.34)  LDD2199  [18]
 LDCM0589  Fragment31 Ramos C885(0.82); C402(1.34); C1673(0.82)  LDD2200  [18]
 LDCM0590  Fragment32 Ramos C885(1.03); C402(1.27)  LDD2201  [18]
 LDCM0468  Fragment33 HCT 116 C240(0.70); C255(0.75); C262(0.80); C366(1.28)  LDD0785  [6]
 LDCM0596  Fragment38 Ramos C885(0.96); C402(1.29); C1673(0.74)  LDD2203  [18]
 LDCM0566  Fragment4 Ramos C885(0.82)  LDD2184  [18]
 LDCM0427  Fragment51 HCT 116 C1709(0.83); C240(1.05); C255(1.05); C402(0.86)  LDD0744  [6]
 LDCM0610  Fragment52 Ramos C885(1.20)  LDD2204  [18]
 LDCM0614  Fragment56 Ramos C885(1.18); C402(2.42); C1673(1.75)  LDD2205  [18]
 LDCM0569  Fragment7 Ramos C885(0.92)  LDD2186  [18]
 LDCM0571  Fragment9 Ramos C885(0.92); C1673(1.02)  LDD2188  [18]
 LDCM0022  KB02 HCT 116 C240(7.54); C262(7.54); C255(7.54); C1616(2.11)  LDD0080  [6]
 LDCM0023  KB03 HCT 116 C240(2.40); C262(2.40); C255(2.40); C1616(1.27)  LDD0081  [6]
 LDCM0024  KB05 HCT 116 C240(3.54); C262(3.54); C255(3.54); C1616(1.88)  LDD0082  [6]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C561(0.80)  LDD2099  [3]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C561(0.57)  LDD2100  [3]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C561(1.24)  LDD2107  [3]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C561(1.04)  LDD2109  [3]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C606(1.51)  LDD2119  [3]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C561(0.58)  LDD2125  [3]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C606(1.04)  LDD2129  [3]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C561(1.13)  LDD2136  [3]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C1270(0.83); C561(0.95)  LDD2137  [3]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C606(1.06); C561(1.03)  LDD2140  [3]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C561(0.64); C885(0.44)  LDD2141  [3]
 LDCM0003  Sulforaphane MDA-MB-231 2.11  LDD0160  [4]
 LDCM0021  THZ1 HCT 116 C366(1.19); C373(1.19); C738(1.17); C746(1.17)  LDD2173  [6]

References

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2 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
3 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
4 Competition-based, quantitative chemical proteomics in breast cancer cells identifies new target profiles for sulforaphane. Chem Commun (Camb). 2017 May 4;53(37):5182-5185. doi: 10.1039/c6cc08797c.
Mass spectrometry data entry: PXD006279
5 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
6 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
7 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
8 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
9 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
10 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
11 Tunable Amine-Reactive Electrophiles for Selective Profiling of Lysine. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202112107. doi: 10.1002/anie.202112107. Epub 2021 Dec 16.
12 Multiplexed CuAAC Suzuki-Miyaura Labeling for Tandem Activity-Based Chemoproteomic Profiling. Anal Chem. 2021 Feb 2;93(4):2610-2618. doi: 10.1021/acs.analchem.0c04726. Epub 2021 Jan 20.
Mass spectrometry data entry: PXD022279
13 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
14 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
15 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
16 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
17 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
18 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578