General Information of Target

Target ID LDTP07207
Target Name Striatin-interacting protein 1 (STRIP1)
Gene Name STRIP1
Gene ID 85369
Synonyms
FAM40A; KIAA1761; Striatin-interacting protein 1; Protein FAM40A
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MEPAVGGPGPLIVNNKQPQPPPPPPPAAAQPPPGAPRAAAGLLPGGKAREFNRNQRKDSE
GYSESPDLEFEYADTDKWAAELSELYSYTEGPEFLMNRKCFEEDFRIHVTDKKWTELDTN
QHRTHAMRLLDGLEVTAREKRLKVARAILYVAQGTFGECSSEAEVQSWMRYNIFLLLEVG
TFNALVELLNMEIDNSAACSSAVRKPAISLADSTDLRVLLNIMYLIVETVHQECEGDKAE
WRTMRQTFRAELGSPLYNNEPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGG
FEELQSMKAEKRSILGLPPLPEDSIKVIRNMRAASPPASASDLIEQQQKRGRREHKALIK
QDNLDAFNERDPYKADDSREEEEENDDDNSLEGETFPLERDEVMPPPLQHPQTDRLTCPK
GLPWAPKVREKDIEMFLESSRSKFIGYTLGSDTNTVVGLPRPIHESIKTLKQHKYTSIAE
VQAQMEEEYLRSPLSGGEEEVEQVPAETLYQGLLPSLPQYMIALLKILLAAAPTSKAKTD
SINILADVLPEEMPTTVLQSMKLGVDVNRHKEVIVKAISAVLLLLLKHFKLNHVYQFEYM
AQHLVFANCIPLILKFFNQNIMSYITAKNSISVLDYPHCVVHELPELTAESLEAGDSNQF
CWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQ
TKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNA
RRYDRAHSNPDFLPVDNCLQSVLGQRVDLPEDFQMNYDLWLEREVFSKPISWEELLQ
Target Bioclass
Other
Family
STRIP family
Subcellular location
Cytoplasm
Function Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape.
Uniprot ID
Q5VSL9
Ensemble ID
ENST00000369795.8
HGNC ID
HGNC:25916

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
AGS SNV: p.K615E .
CASKI SNV: p.S254C .
HCT15 SNV: p.P319L; p.R673W; p.R772H .
HT1080 SNV: p.Q30H .
JURKAT Deletion: p.P319RfsTer9 Compound 10    Probe Info 
KMCH1 SNV: p.K576E .
MDAMB157 SNV: p.C639R .
MFE319 SNV: p.I544T; p.L672F .
MOLT4 SNV: p.Q409H IA-alkyne    Probe Info 
NCIH661 SNV: p.R146L .
REC1 SNV: p.E811G .
TOV21G SNV: p.A530D .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 19 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info 
15.00  LDD0402  [1]
STPyne
 Probe Info 
K699(10.00)  LDD0277  [2]
Probe 1
 Probe Info 
Y62(54.58); Y373(18.59)  LDD3495  [3]
BTD
 Probe Info 
C100(1.24)  LDD2117  [4]
AHL-Pu-1
 Probe Info 
C798(7.58); C769(3.04)  LDD0168  [5]
DBIA
 Probe Info 
C798(2.42)  LDD0080  [6]
4-Iodoacetamidophenylacetylene
 Probe Info 
C798(0.00); C100(0.00); C234(0.00); C668(0.00)  LDD0038  [7]
IA-alkyne
 Probe Info 
C798(0.00); C100(0.00); C769(0.00); C234(0.00)  LDD0036  [7]
Lodoacetamide azide
 Probe Info 
C798(0.00); C100(0.00); C668(0.00); C234(0.00)  LDD0037  [7]
JW-RF-010
 Probe Info 
N.A.  LDD0026  [8]
NAIA_4
 Probe Info 
C418(0.00); C769(0.00); C798(0.00)  LDD2226  [9]
Compound 10
 Probe Info 
N.A.  LDD2216  [10]
IPM
 Probe Info 
N.A.  LDD0147  [8]
TFBX
 Probe Info 
N.A.  LDD0148  [8]
VSF
 Probe Info 
N.A.  LDD0007  [11]
Acrolein
 Probe Info 
N.A.  LDD0217  [12]
W1
 Probe Info 
N.A.  LDD0236  [13]
AOyne
 Probe Info 
12.30  LDD0443  [14]
NAIA_5
 Probe Info 
C798(0.00); C668(0.00)  LDD2223  [9]
PAL-AfBPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
VE-P
 Probe Info 
N.A.  LDD0396  [15]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C100(1.24)  LDD2117  [4]
 LDCM0025  4SU-RNA HEK-293T C798(7.58); C769(3.04)  LDD0168  [5]
 LDCM0026  4SU-RNA+native RNA HEK-293T C798(2.76); C769(2.85)  LDD0169  [5]
 LDCM0214  AC1 HCT 116 C100(1.36); C639(1.08); C661(1.08); C668(0.86)  LDD0531  [6]
 LDCM0215  AC10 HCT 116 C100(1.37); C639(0.86); C661(0.86); C668(0.79)  LDD0532  [6]
 LDCM0216  AC100 HCT 116 C100(0.32); C668(1.17); C798(0.99)  LDD0533  [6]
 LDCM0217  AC101 HCT 116 C100(0.37); C668(0.89); C798(1.09)  LDD0534  [6]
 LDCM0218  AC102 HCT 116 C100(0.26); C668(0.92); C798(0.99)  LDD0535  [6]
 LDCM0219  AC103 HCT 116 C100(0.23); C668(0.79); C798(1.26)  LDD0536  [6]
 LDCM0220  AC104 HCT 116 C100(0.22); C668(0.70); C798(1.03)  LDD0537  [6]
 LDCM0221  AC105 HCT 116 C100(0.28); C668(1.00); C798(1.05)  LDD0538  [6]
 LDCM0222  AC106 HCT 116 C100(0.26); C668(0.83); C798(1.12)  LDD0539  [6]
 LDCM0223  AC107 HCT 116 C100(0.26); C668(0.79); C798(1.12)  LDD0540  [6]
 LDCM0224  AC108 HCT 116 C100(0.58); C668(1.12); C798(0.87)  LDD0541  [6]
 LDCM0225  AC109 HCT 116 C100(0.32); C668(1.04); C798(0.99)  LDD0542  [6]
 LDCM0226  AC11 HCT 116 C100(1.35); C639(0.81); C661(0.81); C668(0.78)  LDD0543  [6]
 LDCM0227  AC110 HCT 116 C100(0.31); C668(0.85); C798(0.96)  LDD0544  [6]
 LDCM0228  AC111 HCT 116 C100(0.42); C668(1.05); C798(1.02)  LDD0545  [6]
 LDCM0229  AC112 HCT 116 C100(0.23); C668(0.62); C798(1.02)  LDD0546  [6]
 LDCM0230  AC113 HCT 116 C100(0.94); C668(1.02); C798(1.03)  LDD0547  [6]
 LDCM0231  AC114 HCT 116 C100(0.93); C668(0.78); C798(1.22)  LDD0548  [6]
 LDCM0232  AC115 HCT 116 C100(0.91); C668(0.73); C798(1.07)  LDD0549  [6]
 LDCM0233  AC116 HCT 116 C100(0.97); C668(0.63); C798(1.19)  LDD0550  [6]
 LDCM0234  AC117 HCT 116 C100(1.04); C668(0.83); C798(1.33)  LDD0551  [6]
 LDCM0235  AC118 HCT 116 C100(1.19); C668(0.85); C798(1.20)  LDD0552  [6]
 LDCM0236  AC119 HCT 116 C100(0.89); C668(0.67); C798(1.37)  LDD0553  [6]
 LDCM0237  AC12 HCT 116 C100(1.76); C639(0.83); C661(0.83); C668(0.87)  LDD0554  [6]
 LDCM0238  AC120 HCT 116 C100(0.82); C668(0.55); C798(1.25)  LDD0555  [6]
 LDCM0239  AC121 HCT 116 C100(1.23); C668(1.11); C798(1.25)  LDD0556  [6]
 LDCM0240  AC122 HCT 116 C100(1.01); C668(0.79); C798(1.06)  LDD0557  [6]
 LDCM0241  AC123 HCT 116 C100(1.30); C668(0.94); C798(1.04)  LDD0558  [6]
 LDCM0242  AC124 HCT 116 C100(1.04); C668(1.03); C798(1.29)  LDD0559  [6]
 LDCM0243  AC125 HCT 116 C100(1.00); C668(0.89); C798(1.26)  LDD0560  [6]
 LDCM0244  AC126 HCT 116 C100(1.17); C668(0.65); C798(1.07)  LDD0561  [6]
 LDCM0245  AC127 HCT 116 C100(1.02); C668(0.70); C798(1.37)  LDD0562  [6]
 LDCM0246  AC128 HCT 116 C100(1.03); C668(0.99); C798(1.23)  LDD0563  [6]
 LDCM0247  AC129 HCT 116 C100(1.40); C668(1.60); C798(0.87)  LDD0564  [6]
 LDCM0249  AC130 HCT 116 C100(1.04); C668(1.12); C798(1.06)  LDD0566  [6]
 LDCM0250  AC131 HCT 116 C100(1.05); C668(1.31); C798(1.17)  LDD0567  [6]
 LDCM0251  AC132 HCT 116 C100(1.26); C668(1.59); C798(1.15)  LDD0568  [6]
 LDCM0252  AC133 HCT 116 C100(0.98); C668(1.17); C798(1.12)  LDD0569  [6]
 LDCM0253  AC134 HCT 116 C100(0.96); C668(1.23); C798(1.21)  LDD0570  [6]
 LDCM0254  AC135 HCT 116 C100(1.14); C668(1.29); C798(1.05)  LDD0571  [6]
 LDCM0255  AC136 HCT 116 C100(0.91); C668(1.05); C798(1.13)  LDD0572  [6]
 LDCM0256  AC137 HCT 116 C100(1.09); C668(1.20); C798(1.04)  LDD0573  [6]
 LDCM0257  AC138 HCT 116 C100(1.05); C668(1.22); C798(1.19)  LDD0574  [6]
 LDCM0258  AC139 HCT 116 C100(1.03); C668(1.22); C798(1.18)  LDD0575  [6]
 LDCM0259  AC14 HCT 116 C100(1.34); C639(0.69); C661(0.69); C668(0.86)  LDD0576  [6]
 LDCM0260  AC140 HCT 116 C100(1.16); C668(1.29); C798(1.29)  LDD0577  [6]
 LDCM0261  AC141 HCT 116 C100(1.01); C668(1.29); C798(1.28)  LDD0578  [6]
 LDCM0262  AC142 HCT 116 C100(1.20); C668(1.48); C798(1.12)  LDD0579  [6]
 LDCM0263  AC143 HCT 116 C668(0.88); C100(0.93); C798(1.12)  LDD0580  [6]
 LDCM0264  AC144 HCT 116 C668(0.51); C100(0.81); C798(1.31)  LDD0581  [6]
 LDCM0265  AC145 HCT 116 C668(0.67); C100(0.98); C798(1.37)  LDD0582  [6]
 LDCM0266  AC146 HCT 116 C668(0.65); C100(0.73); C798(1.18)  LDD0583  [6]
 LDCM0267  AC147 HCT 116 C668(0.41); C100(0.86); C798(1.15)  LDD0584  [6]
 LDCM0268  AC148 HCT 116 C668(0.43); C100(0.78); C798(2.44)  LDD0585  [6]
 LDCM0269  AC149 HCT 116 C668(0.44); C100(0.68); C798(2.14)  LDD0586  [6]
 LDCM0270  AC15 HCT 116 C639(0.71); C661(0.71); C668(0.72); C769(1.18)  LDD0587  [6]
 LDCM0271  AC150 HCT 116 C668(0.81); C100(0.86); C798(0.93)  LDD0588  [6]
 LDCM0272  AC151 HCT 116 C668(0.77); C100(0.82); C798(0.88)  LDD0589  [6]
 LDCM0273  AC152 HCT 116 C668(0.40); C100(0.65); C798(1.17)  LDD0590  [6]
 LDCM0274  AC153 HCT 116 C668(0.48); C100(0.68); C798(2.09)  LDD0591  [6]
 LDCM0621  AC154 HCT 116 C100(0.84); C668(0.52); C798(1.09)  LDD2158  [6]
 LDCM0622  AC155 HCT 116 C100(0.81); C668(0.45); C798(1.33)  LDD2159  [6]
 LDCM0623  AC156 HCT 116 C100(0.90); C668(0.77); C798(0.95)  LDD2160  [6]
 LDCM0624  AC157 HCT 116 C100(0.93); C668(1.01); C798(0.90)  LDD2161  [6]
 LDCM0276  AC17 HCT 116 C668(0.85); C100(0.91); C798(1.09); C769(1.11)  LDD0593  [6]
 LDCM0277  AC18 HCT 116 C668(0.55); C100(0.75); C798(1.65); C769(2.66)  LDD0594  [6]
 LDCM0278  AC19 HCT 116 C668(0.70); C100(0.82); C798(0.98); C769(1.40)  LDD0595  [6]
 LDCM0279  AC2 HCT 116 C668(0.92); C639(1.08); C661(1.08); C798(1.09)  LDD0596  [6]
 LDCM0280  AC20 HCT 116 C668(0.82); C100(0.87); C798(1.01); C769(1.15)  LDD0597  [6]
 LDCM0281  AC21 HCT 116 C668(0.65); C100(0.83); C798(1.13); C769(1.80)  LDD0598  [6]
 LDCM0282  AC22 HCT 116 C668(0.93); C100(1.05); C798(1.06); C769(1.14)  LDD0599  [6]
 LDCM0283  AC23 HCT 116 C668(0.87); C100(0.90); C798(1.04); C769(1.37)  LDD0600  [6]
 LDCM0284  AC24 HCT 116 C100(0.93); C798(0.98); C668(1.03); C769(1.21)  LDD0601  [6]
 LDCM0285  AC25 HCT 116 C668(0.75); C100(1.02); C798(1.31)  LDD0602  [6]
 LDCM0286  AC26 HCT 116 C668(0.61); C100(0.87); C798(1.37)  LDD0603  [6]
 LDCM0287  AC27 HCT 116 C668(0.59); C100(0.83); C798(1.33)  LDD0604  [6]
 LDCM0288  AC28 HCT 116 C668(0.51); C100(0.80); C798(1.37)  LDD0605  [6]
 LDCM0289  AC29 HCT 116 C668(0.62); C100(0.97); C798(1.42)  LDD0606  [6]
 LDCM0290  AC3 HCT 116 C668(0.98); C639(1.12); C661(1.12); C798(1.13)  LDD0607  [6]
 LDCM0291  AC30 HCT 116 C668(0.59); C100(0.85); C798(1.34)  LDD0608  [6]
 LDCM0292  AC31 HCT 116 C668(0.55); C100(0.79); C798(1.19)  LDD0609  [6]
 LDCM0293  AC32 HCT 116 C668(0.45); C100(0.77); C798(1.59)  LDD0610  [6]
 LDCM0294  AC33 HCT 116 C668(0.49); C100(0.76); C798(1.61)  LDD0611  [6]
 LDCM0295  AC34 HCT 116 C668(0.44); C100(0.71); C798(1.37)  LDD0612  [6]
 LDCM0296  AC35 HCT 116 C798(0.99); C100(1.12); C668(1.25)  LDD0613  [6]
 LDCM0297  AC36 HCT 116 C100(1.15); C798(1.34); C668(1.38)  LDD0614  [6]
 LDCM0298  AC37 HCT 116 C100(1.14); C798(1.28); C668(1.51)  LDD0615  [6]
 LDCM0299  AC38 HCT 116 C668(1.13); C798(1.21); C100(1.22)  LDD0616  [6]
 LDCM0300  AC39 HCT 116 C668(1.03); C100(1.06); C798(1.47)  LDD0617  [6]
 LDCM0301  AC4 HCT 116 C639(0.86); C661(0.86); C668(0.91); C798(1.23)  LDD0618  [6]
 LDCM0302  AC40 HCT 116 C100(0.93); C668(1.04); C798(1.30)  LDD0619  [6]
 LDCM0303  AC41 HCT 116 C100(1.00); C798(1.06); C668(1.30)  LDD0620  [6]
 LDCM0304  AC42 HCT 116 C100(0.98); C798(1.05); C668(1.07)  LDD0621  [6]
 LDCM0305  AC43 HCT 116 C798(1.04); C100(1.05); C668(1.30)  LDD0622  [6]
 LDCM0306  AC44 HCT 116 C100(1.09); C668(1.24); C798(1.34)  LDD0623  [6]
 LDCM0307  AC45 HCT 116 C100(0.97); C668(1.06); C798(1.39)  LDD0624  [6]
 LDCM0308  AC46 HCT 116 C668(0.86); C100(1.03); C798(1.16); C769(1.66)  LDD0625  [6]
 LDCM0309  AC47 HCT 116 C769(0.73); C668(0.82); C100(0.99); C798(1.01)  LDD0626  [6]
 LDCM0310  AC48 HCT 116 C798(0.74); C668(0.83); C769(0.84); C100(1.09)  LDD0627  [6]
 LDCM0311  AC49 HCT 116 C668(0.75); C100(0.79); C769(0.81); C798(0.85)  LDD0628  [6]
 LDCM0312  AC5 HCT 116 C668(0.91); C798(1.28); C639(1.37); C661(1.37)  LDD0629  [6]
 LDCM0313  AC50 HCT 116 C668(0.83); C100(0.87); C798(1.23); C769(1.25)  LDD0630  [6]
 LDCM0314  AC51 HCT 116 C798(0.74); C100(1.08); C668(1.10); C769(1.21)  LDD0631  [6]
 LDCM0315  AC52 HCT 116 C798(0.81); C668(0.84); C769(0.86); C100(0.96)  LDD0632  [6]
 LDCM0316  AC53 HCT 116 C769(0.77); C100(0.82); C668(0.95); C798(1.30)  LDD0633  [6]
 LDCM0317  AC54 HCT 116 C798(0.81); C668(0.84); C769(0.89); C100(0.95)  LDD0634  [6]
 LDCM0318  AC55 HCT 116 C769(0.76); C798(0.87); C100(0.92); C668(0.96)  LDD0635  [6]
 LDCM0319  AC56 HCT 116 C769(0.70); C100(0.96); C668(1.03); C798(1.84)  LDD0636  [6]
 LDCM0320  AC57 HCT 116 C668(0.79); C100(0.91); C798(0.95)  LDD0637  [6]
 LDCM0321  AC58 HCT 116 C668(0.78); C100(0.94); C798(1.20)  LDD0638  [6]
 LDCM0322  AC59 HCT 116 C100(0.72); C668(0.77); C798(1.31)  LDD0639  [6]
 LDCM0323  AC6 HCT 116 C668(0.73); C639(0.82); C661(0.82); C100(1.18)  LDD0640  [6]
 LDCM0324  AC60 HCT 116 C100(0.70); C668(0.71); C798(1.25)  LDD0641  [6]
 LDCM0325  AC61 HCT 116 C100(0.65); C668(0.74); C798(0.93)  LDD0642  [6]
 LDCM0326  AC62 HCT 116 C100(0.75); C668(0.81); C798(1.54)  LDD0643  [6]
 LDCM0327  AC63 HCT 116 C668(0.70); C100(0.75); C798(1.28)  LDD0644  [6]
 LDCM0328  AC64 HCT 116 C668(0.78); C100(0.83); C798(1.22)  LDD0645  [6]
 LDCM0329  AC65 HCT 116 C668(0.83); C100(0.88); C798(1.13)  LDD0646  [6]
 LDCM0330  AC66 HCT 116 C668(0.83); C100(0.86); C798(1.03)  LDD0647  [6]
 LDCM0331  AC67 HCT 116 C100(0.67); C668(0.74); C798(1.22)  LDD0648  [6]
 LDCM0332  AC68 HCT 116 C100(0.78); C769(0.84); C668(0.91); C798(1.09)  LDD0649  [6]
 LDCM0333  AC69 HCT 116 C639(0.43); C661(0.43); C769(0.75); C668(0.84)  LDD0650  [6]
 LDCM0334  AC7 HCT 116 C639(0.82); C661(0.82); C668(0.84); C798(1.41)  LDD0651  [6]
 LDCM0335  AC70 HCT 116 C639(0.55); C661(0.55); C668(0.75); C769(0.86)  LDD0652  [6]
 LDCM0336  AC71 HCT 116 C639(0.76); C661(0.76); C668(0.97); C769(0.98)  LDD0653  [6]
 LDCM0337  AC72 HCT 116 C639(0.47); C661(0.47); C668(0.83); C100(0.98)  LDD0654  [6]
 LDCM0338  AC73 HCT 116 C639(0.67); C661(0.67); C668(0.97); C100(0.97)  LDD0655  [6]
 LDCM0339  AC74 HCT 116 C639(0.76); C661(0.76); C769(0.88); C668(1.00)  LDD0656  [6]
 LDCM0340  AC75 HCT 116 C639(0.70); C661(0.70); C100(0.91); C668(1.03)  LDD0657  [6]
 LDCM0341  AC76 HCT 116 C639(0.71); C661(0.71); C668(0.91); C100(1.13)  LDD0658  [6]
 LDCM0342  AC77 HCT 116 C639(0.86); C661(0.86); C769(0.90); C100(0.93)  LDD0659  [6]
 LDCM0343  AC78 HCT 116 C639(0.79); C661(0.79); C668(0.84); C769(1.02)  LDD0660  [6]
 LDCM0344  AC79 HCT 116 C639(0.41); C661(0.41); C100(0.76); C769(0.88)  LDD0661  [6]
 LDCM0345  AC8 HCT 116 C639(0.65); C661(0.65); C668(0.72); C769(1.21)  LDD0662  [6]
 LDCM0346  AC80 HCT 116 C639(0.58); C661(0.58); C668(0.94); C769(1.22)  LDD0663  [6]
 LDCM0347  AC81 HCT 116 C668(0.77); C639(0.77); C661(0.77); C100(0.92)  LDD0664  [6]
 LDCM0348  AC82 HCT 116 C639(0.64); C661(0.64); C668(1.03); C769(1.07)  LDD0665  [6]
 LDCM0349  AC83 HCT 116 C668(0.56); C100(0.63); C639(0.89); C661(0.89)  LDD0666  [6]
 LDCM0350  AC84 HCT 116 C668(0.49); C100(0.64); C639(0.76); C661(0.76)  LDD0667  [6]
 LDCM0351  AC85 HCT 116 C668(0.56); C100(0.74); C769(1.18); C639(1.22)  LDD0668  [6]
 LDCM0352  AC86 HCT 116 C668(0.63); C100(0.72); C769(1.08); C798(1.20)  LDD0669  [6]
 LDCM0353  AC87 HCT 116 C668(0.72); C100(0.84); C798(0.99); C639(1.00)  LDD0670  [6]
 LDCM0354  AC88 HCT 116 C668(0.71); C100(0.79); C769(0.92); C798(1.19)  LDD0671  [6]
 LDCM0355  AC89 HCT 116 C100(0.63); C668(0.65); C639(0.99); C661(0.99)  LDD0672  [6]
 LDCM0357  AC90 HCT 116 C798(0.81); C769(1.09); C668(1.26); C100(1.38)  LDD0674  [6]
 LDCM0358  AC91 HCT 116 C668(0.54); C100(0.73); C639(1.01); C661(1.01)  LDD0675  [6]
 LDCM0359  AC92 HCT 116 C668(0.52); C100(0.72); C639(1.11); C661(1.11)  LDD0676  [6]
 LDCM0360  AC93 HCT 116 C668(0.54); C100(0.68); C639(0.91); C661(0.91)  LDD0677  [6]
 LDCM0361  AC94 HCT 116 C668(0.56); C639(0.67); C661(0.67); C100(0.80)  LDD0678  [6]
 LDCM0362  AC95 HCT 116 C668(0.65); C100(0.76); C769(0.92); C639(1.03)  LDD0679  [6]
 LDCM0363  AC96 HCT 116 C668(0.52); C100(0.85); C639(1.05); C661(1.05)  LDD0680  [6]
 LDCM0364  AC97 HCT 116 C668(0.50); C100(0.59); C639(0.85); C661(0.85)  LDD0681  [6]
 LDCM0365  AC98 HCT 116 C100(0.24); C668(0.66); C798(1.34)  LDD0682  [6]
 LDCM0366  AC99 HCT 116 C100(0.37); C798(1.03); C668(1.28)  LDD0683  [6]
 LDCM0248  AKOS034007472 HCT 116 C100(1.59); C639(1.25); C661(1.25); C668(0.98)  LDD0565  [6]
 LDCM0356  AKOS034007680 HCT 116 C639(0.84); C661(0.84); C668(0.86); C100(1.23)  LDD0673  [6]
 LDCM0275  AKOS034007705 HCT 116 C639(0.61); C661(0.61); C668(0.64); C100(1.46)  LDD0592  [6]
 LDCM0630  CCW28-3 231MFP C798(1.26)  LDD2214  [16]
 LDCM0632  CL-Sc Hep-G2 C798(1.03)  LDD2227  [9]
 LDCM0367  CL1 HCT 116 C639(0.82); C661(0.82); C668(1.05); C798(1.11)  LDD0684  [6]
 LDCM0368  CL10 HCT 116 C639(0.70); C661(0.70); C798(0.86); C668(1.00)  LDD0685  [6]
 LDCM0369  CL100 HCT 116 C668(0.88); C639(0.96); C661(0.96); C798(1.06)  LDD0686  [6]
 LDCM0370  CL101 HCT 116 C668(0.74); C639(0.83); C661(0.83); C100(1.17)  LDD0687  [6]
 LDCM0371  CL102 HCT 116 C668(0.89); C639(0.93); C661(0.93); C798(1.06)  LDD0688  [6]
 LDCM0372  CL103 HCT 116 C639(0.86); C661(0.86); C668(1.01); C798(1.12)  LDD0689  [6]
 LDCM0373  CL104 HCT 116 C668(0.91); C639(1.06); C661(1.06); C798(1.10)  LDD0690  [6]
 LDCM0374  CL105 HCT 116 C668(0.65); C100(0.76); C798(1.19); C769(1.71)  LDD0691  [6]
 LDCM0375  CL106 HCT 116 C668(0.50); C100(0.76); C798(1.48); C769(1.73)  LDD0692  [6]
 LDCM0376  CL107 HCT 116 C668(0.60); C100(0.77); C798(1.51); C769(1.83)  LDD0693  [6]
 LDCM0377  CL108 HCT 116 C668(0.55); C100(0.84); C798(1.49); C769(2.37)  LDD0694  [6]
 LDCM0378  CL109 HCT 116 C668(0.67); C100(0.69); C798(1.29); C769(1.31)  LDD0695  [6]
 LDCM0379  CL11 HCT 116 C639(0.86); C661(0.86); C668(0.94); C798(0.95)  LDD0696  [6]
 LDCM0380  CL110 HCT 116 C668(0.61); C100(0.80); C798(1.22); C769(1.86)  LDD0697  [6]
 LDCM0381  CL111 HCT 116 C668(0.65); C100(0.67); C798(1.05); C769(1.84)  LDD0698  [6]
 LDCM0382  CL112 HCT 116 C668(0.77); C100(0.90); C798(0.92)  LDD0699  [6]
 LDCM0383  CL113 HCT 116 C668(0.45); C100(0.75); C798(1.73)  LDD0700  [6]
 LDCM0384  CL114 HCT 116 C668(0.74); C100(0.81); C798(1.04)  LDD0701  [6]
 LDCM0385  CL115 HCT 116 C668(0.55); C100(0.80); C798(1.37)  LDD0702  [6]
 LDCM0386  CL116 HCT 116 C668(0.62); C100(0.94); C798(1.48)  LDD0703  [6]
 LDCM0387  CL117 HCT 116 C100(1.01); C668(1.42); C798(2.04)  LDD0704  [6]
 LDCM0388  CL118 HCT 116 C100(1.05); C668(1.20); C798(1.35)  LDD0705  [6]
 LDCM0389  CL119 HCT 116 C100(0.94); C668(0.95); C798(1.85)  LDD0706  [6]
 LDCM0390  CL12 HCT 116 C639(0.78); C661(0.78); C798(0.95); C668(1.09)  LDD0707  [6]
 LDCM0391  CL120 HCT 116 C798(1.04); C100(1.21); C668(1.39)  LDD0708  [6]
 LDCM0392  CL121 HCT 116 C100(0.84); C769(0.88); C668(0.99); C798(1.43)  LDD0709  [6]
 LDCM0393  CL122 HCT 116 C769(0.62); C668(0.78); C100(0.89); C798(0.90)  LDD0710  [6]
 LDCM0394  CL123 HCT 116 C100(0.80); C668(0.86); C798(1.13); C769(2.48)  LDD0711  [6]
 LDCM0395  CL124 HCT 116 C668(0.87); C769(0.98); C100(1.00); C798(1.25)  LDD0712  [6]
 LDCM0396  CL125 HCT 116 C100(0.93); C668(0.94); C798(0.95)  LDD0713  [6]
 LDCM0397  CL126 HCT 116 C100(0.79); C798(0.84); C668(0.87)  LDD0714  [6]
 LDCM0398  CL127 HCT 116 C100(0.80); C668(0.84); C798(0.94)  LDD0715  [6]
 LDCM0399  CL128 HCT 116 C668(0.81); C100(0.86); C798(1.12)  LDD0716  [6]
 LDCM0400  CL13 HCT 116 C639(0.64); C661(0.64); C798(0.92); C668(1.04)  LDD0717  [6]
 LDCM0401  CL14 HCT 116 C798(0.94); C639(1.04); C661(1.04); C668(1.07)  LDD0718  [6]
 LDCM0402  CL15 HCT 116 C639(0.66); C661(0.66); C798(0.96); C668(0.98)  LDD0719  [6]
 LDCM0403  CL16 HCT 116 C100(0.94); C798(1.15); C769(1.16)  LDD0720  [6]
 LDCM0404  CL17 HCT 116 C798(1.10); C100(1.18); C769(1.52)  LDD0721  [6]
 LDCM0405  CL18 HCT 116 C100(1.02); C798(1.09); C769(1.91)  LDD0722  [6]
 LDCM0406  CL19 HCT 116 C100(1.01); C798(1.02); C769(1.22)  LDD0723  [6]
 LDCM0407  CL2 HCT 116 C639(0.85); C661(0.85); C798(0.93); C668(1.02)  LDD0724  [6]
 LDCM0408  CL20 HCT 116 C100(1.03); C769(1.10); C798(1.22)  LDD0725  [6]
 LDCM0409  CL21 HCT 116 C100(1.18); C798(1.26); C769(1.40)  LDD0726  [6]
 LDCM0410  CL22 HCT 116 C100(1.17); C798(1.57); C769(1.83)  LDD0727  [6]
 LDCM0411  CL23 HCT 116 C100(0.82); C769(1.11); C798(1.38)  LDD0728  [6]
 LDCM0412  CL24 HCT 116 C100(1.03); C769(1.60); C798(1.30)  LDD0729  [6]
 LDCM0413  CL25 HCT 116 C100(1.01); C769(1.66); C798(1.39)  LDD0730  [6]
 LDCM0414  CL26 HCT 116 C100(0.98); C769(1.46); C798(1.21)  LDD0731  [6]
 LDCM0415  CL27 HCT 116 C100(0.91); C769(1.24); C798(1.25)  LDD0732  [6]
 LDCM0416  CL28 HCT 116 C100(1.05); C769(1.49); C798(1.27)  LDD0733  [6]
 LDCM0417  CL29 HCT 116 C100(1.01); C769(1.01); C798(1.19)  LDD0734  [6]
 LDCM0418  CL3 HCT 116 C100(1.35); C639(1.22); C661(1.22); C668(0.96)  LDD0735  [6]
 LDCM0419  CL30 HCT 116 C100(1.05); C769(0.93); C798(1.14)  LDD0736  [6]
 LDCM0420  CL31 HCT 116 C100(0.87); C668(0.89); C798(1.34)  LDD0737  [6]
 LDCM0421  CL32 HCT 116 C100(0.78); C668(0.71); C798(1.20)  LDD0738  [6]
 LDCM0422  CL33 HCT 116 C100(0.76); C668(0.73); C798(1.18)  LDD0739  [6]
 LDCM0423  CL34 HCT 116 C100(0.71); C668(0.68); C798(1.37)  LDD0740  [6]
 LDCM0424  CL35 HCT 116 C100(0.77); C668(0.72); C798(1.44)  LDD0741  [6]
 LDCM0425  CL36 HCT 116 C100(0.78); C668(0.79); C798(1.23)  LDD0742  [6]
 LDCM0426  CL37 HCT 116 C100(0.95); C668(0.75); C798(1.19)  LDD0743  [6]
 LDCM0428  CL39 HCT 116 C100(0.86); C668(0.80); C798(1.22)  LDD0745  [6]
 LDCM0429  CL4 HCT 116 C100(1.26); C639(0.97); C661(0.97); C668(1.03)  LDD0746  [6]
 LDCM0430  CL40 HCT 116 C100(0.83); C668(0.82); C798(1.27)  LDD0747  [6]
 LDCM0431  CL41 HCT 116 C100(0.76); C668(0.86); C798(1.01)  LDD0748  [6]
 LDCM0432  CL42 HCT 116 C100(0.85); C668(0.85); C798(1.13)  LDD0749  [6]
 LDCM0433  CL43 HCT 116 C100(0.82); C668(0.80); C798(1.17)  LDD0750  [6]
 LDCM0434  CL44 HCT 116 C100(0.89); C668(0.67); C798(1.11)  LDD0751  [6]
 LDCM0435  CL45 HCT 116 C100(0.91); C668(0.80); C798(0.97)  LDD0752  [6]
 LDCM0436  CL46 HCT 116 C100(1.31); C668(1.27); C769(1.09); C798(0.81)  LDD0753  [6]
 LDCM0437  CL47 HCT 116 C100(1.23); C668(1.20); C769(1.45); C798(0.83)  LDD0754  [6]
 LDCM0438  CL48 HCT 116 C100(1.40); C668(1.36); C769(1.43); C798(0.80)  LDD0755  [6]
 LDCM0439  CL49 HCT 116 C100(1.21); C668(1.14); C769(1.29); C798(0.99)  LDD0756  [6]
 LDCM0440  CL5 HCT 116 C100(1.33); C639(0.83); C661(0.83); C668(1.05)  LDD0757  [6]
 LDCM0441  CL50 HCT 116 C100(1.30); C668(1.35); C769(1.23); C798(1.01)  LDD0758  [6]
 LDCM0442  CL51 HCT 116 C100(1.42); C668(1.32); C769(2.05); C798(0.86)  LDD0759  [6]
 LDCM0443  CL52 HCT 116 C100(1.41); C668(1.38); C769(1.42); C798(0.91)  LDD0760  [6]
 LDCM0444  CL53 HCT 116 C100(1.38); C668(1.31); C769(1.34); C798(0.83)  LDD0761  [6]
 LDCM0445  CL54 HCT 116 C100(1.24); C668(1.33); C769(1.16); C798(0.79)  LDD0762  [6]
 LDCM0446  CL55 HCT 116 C100(1.53); C668(1.35); C769(0.89); C798(0.81)  LDD0763  [6]
 LDCM0447  CL56 HCT 116 C100(1.10); C668(1.06); C769(1.25); C798(0.98)  LDD0764  [6]
 LDCM0448  CL57 HCT 116 C100(1.41); C668(1.29); C769(1.18); C798(0.84)  LDD0765  [6]
 LDCM0449  CL58 HCT 116 C100(1.40); C668(1.25); C769(1.14); C798(0.85)  LDD0766  [6]
 LDCM0450  CL59 HCT 116 C100(1.25); C668(1.14); C769(1.21); C798(1.05)  LDD0767  [6]
 LDCM0451  CL6 HCT 116 C100(1.11); C639(0.91); C661(0.91); C668(0.92)  LDD0768  [6]
 LDCM0452  CL60 HCT 116 C100(1.04); C668(1.02); C769(1.18); C798(0.93)  LDD0769  [6]
 LDCM0453  CL61 HCT 116 C100(1.03); C668(0.97)  LDD0770  [6]
 LDCM0454  CL62 HCT 116 C100(1.02); C668(0.94)  LDD0771  [6]
 LDCM0455  CL63 HCT 116 C100(1.01); C668(0.87)  LDD0772  [6]
 LDCM0456  CL64 HCT 116 C100(0.90); C668(0.75)  LDD0773  [6]
 LDCM0457  CL65 HCT 116 C100(0.94); C668(0.89)  LDD0774  [6]
 LDCM0458  CL66 HCT 116 C100(0.79); C668(0.80)  LDD0775  [6]
 LDCM0459  CL67 HCT 116 C100(0.85); C668(0.69)  LDD0776  [6]
 LDCM0460  CL68 HCT 116 C100(0.75); C668(0.83)  LDD0777  [6]
 LDCM0461  CL69 HCT 116 C100(0.85); C668(0.76)  LDD0778  [6]
 LDCM0462  CL7 HCT 116 C100(1.28); C639(1.07); C661(1.07); C668(1.12)  LDD0779  [6]
 LDCM0463  CL70 HCT 116 C100(0.83); C668(0.81)  LDD0780  [6]
 LDCM0464  CL71 HCT 116 C100(0.83); C668(0.78)  LDD0781  [6]
 LDCM0465  CL72 HCT 116 C100(0.96); C668(0.81)  LDD0782  [6]
 LDCM0466  CL73 HCT 116 C100(0.97); C668(0.76)  LDD0783  [6]
 LDCM0467  CL74 HCT 116 C100(0.82); C668(0.80)  LDD0784  [6]
 LDCM0469  CL76 HCT 116 C100(1.00); C668(0.87); C769(0.86)  LDD0786  [6]
 LDCM0470  CL77 HCT 116 C100(0.96); C668(0.96); C769(0.94)  LDD0787  [6]
 LDCM0471  CL78 HCT 116 C100(0.96); C668(0.95); C769(0.83)  LDD0788  [6]
 LDCM0472  CL79 HCT 116 C100(1.18); C668(0.78); C769(1.02)  LDD0789  [6]
 LDCM0473  CL8 HCT 116 C100(0.87); C639(1.04); C661(1.04); C668(0.94)  LDD0790  [6]
 LDCM0474  CL80 HCT 116 C100(1.09); C668(0.86); C769(1.09)  LDD0791  [6]
 LDCM0475  CL81 HCT 116 C100(1.25); C668(0.92); C769(0.92)  LDD0792  [6]
 LDCM0476  CL82 HCT 116 C100(1.32); C668(0.92); C769(0.80)  LDD0793  [6]
 LDCM0477  CL83 HCT 116 C100(1.15); C668(0.86); C769(1.22)  LDD0794  [6]
 LDCM0478  CL84 HCT 116 C100(1.04); C668(0.98); C769(0.97)  LDD0795  [6]
 LDCM0479  CL85 HCT 116 C100(0.93); C668(0.89); C769(0.97)  LDD0796  [6]
 LDCM0480  CL86 HCT 116 C100(1.02); C668(0.93); C769(0.82)  LDD0797  [6]
 LDCM0481  CL87 HCT 116 C100(1.27); C668(0.87); C769(0.94)  LDD0798  [6]
 LDCM0482  CL88 HCT 116 C100(1.29); C668(0.88); C769(0.76)  LDD0799  [6]
 LDCM0483  CL89 HCT 116 C100(1.09); C668(1.10); C769(0.74)  LDD0800  [6]
 LDCM0484  CL9 HCT 116 C100(1.20); C639(0.87); C661(0.87); C668(0.98)  LDD0801  [6]
 LDCM0485  CL90 HCT 116 C100(1.08); C668(1.21); C769(1.61)  LDD0802  [6]
 LDCM0486  CL91 HCT 116 C100(0.93); C639(1.18); C661(1.18); C668(0.82)  LDD0803  [6]
 LDCM0487  CL92 HCT 116 C100(1.08); C639(1.09); C661(1.09); C668(0.85)  LDD0804  [6]
 LDCM0488  CL93 HCT 116 C100(1.29); C639(1.36); C661(1.36); C668(1.01)  LDD0805  [6]
 LDCM0489  CL94 HCT 116 C100(1.04); C639(1.08); C661(1.08); C668(0.91)  LDD0806  [6]
 LDCM0490  CL95 HCT 116 C100(1.10); C639(1.01); C661(1.01); C668(0.82)  LDD0807  [6]
 LDCM0491  CL96 HCT 116 C100(1.13); C639(1.12); C661(1.12); C668(0.93)  LDD0808  [6]
 LDCM0492  CL97 HCT 116 C100(1.01); C639(1.04); C661(1.04); C668(0.79)  LDD0809  [6]
 LDCM0493  CL98 HCT 116 C100(1.07); C639(0.94); C661(0.94); C668(0.82)  LDD0810  [6]
 LDCM0494  CL99 HCT 116 C100(1.15); C639(0.99); C661(0.99); C668(0.85)  LDD0811  [6]
 LDCM0495  E2913 HEK-293T C274(1.23); C100(1.18); C769(0.86); C668(1.09)  LDD1698  [17]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C668(2.51)  LDD1702  [4]
 LDCM0625  F8 Ramos C798(1.14)  LDD2187  [18]
 LDCM0572  Fragment10 Ramos C798(0.69)  LDD2189  [18]
 LDCM0574  Fragment12 Ramos C798(0.67)  LDD2191  [18]
 LDCM0575  Fragment13 Ramos C798(0.67)  LDD2192  [18]
 LDCM0576  Fragment14 Ramos C798(1.05)  LDD2193  [18]
 LDCM0579  Fragment20 Ramos C798(0.55)  LDD2194  [18]
 LDCM0580  Fragment21 Ramos C798(0.74)  LDD2195  [18]
 LDCM0582  Fragment23 Ramos C798(1.01)  LDD2196  [18]
 LDCM0578  Fragment27 Ramos C798(0.77)  LDD2197  [18]
 LDCM0586  Fragment28 Ramos C798(0.91)  LDD2198  [18]
 LDCM0588  Fragment30 Ramos C798(1.68)  LDD2199  [18]
 LDCM0589  Fragment31 Ramos C798(0.70)  LDD2200  [18]
 LDCM0590  Fragment32 Ramos C798(0.65)  LDD2201  [18]
 LDCM0468  Fragment33 HCT 116 C100(0.83); C668(0.78)  LDD0785  [6]
 LDCM0596  Fragment38 Ramos C798(0.49)  LDD2203  [18]
 LDCM0566  Fragment4 Ramos C798(0.86)  LDD2184  [18]
 LDCM0427  Fragment51 HCT 116 C100(0.85); C668(0.95); C798(1.02)  LDD0744  [6]
 LDCM0610  Fragment52 Ramos C798(0.75)  LDD2204  [18]
 LDCM0614  Fragment56 Ramos C798(0.72)  LDD2205  [18]
 LDCM0569  Fragment7 Ramos C798(0.80)  LDD2186  [18]
 LDCM0571  Fragment9 Ramos C798(0.67)  LDD2188  [18]
 LDCM0022  KB02 HCT 116 C798(2.42)  LDD0080  [6]
 LDCM0023  KB03 HCT 116 C798(2.45)  LDD0081  [6]
 LDCM0024  KB05 HCT 116 C798(3.32)  LDD0082  [6]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C100(2.07)  LDD2125  [4]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C100(1.68)  LDD2137  [4]
 LDCM0627  NUDT7-COV-1 HEK-293T C798(1.05)  LDD2206  [19]
 LDCM0628  OTUB2-COV-1 HEK-293T C798(0.67)  LDD2207  [19]
 LDCM0131  RA190 MM1.R C798(1.92)  LDD0304  [20]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PPP2CA) PPP phosphatase family P67775
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PPP2CB) PPP phosphatase family P62714
Serine/threonine-protein kinase 24 (STK24) STE Ser/Thr protein kinase family Q9Y6E0
Serine/threonine-protein kinase 26 (STK26) STE Ser/Thr protein kinase family Q9P289
Other
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
CTTNBP2 N-terminal-like protein (CTTNBP2NL) . Q9P2B4
TRAF3-interacting JNK-activating modulator (TRAF3IP3) . Q9Y228

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
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Mass spectrometry data entry: PXD028270
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Mass spectrometry data entry: PXD039908 , PXD029761
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Mass spectrometry data entry: PXD044625
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Mass spectrometry data entry: PXD028853
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Mass spectrometry data entry: PXD029255
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Mass spectrometry data entry: PXD041264
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Mass spectrometry data entry: PXD022279
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Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
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Mass spectrometry data entry: PXD044402
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Mass spectrometry data entry: PXD027578
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