General Information of Experiment

Probe Name 2PCA  Probe Info 
Probe concentration 10 uM
Criteria Qualitation: Labeling site identification
In Vivo Experiment Model Model Type Cell lysate
Derived Tissue Peripheral blood
Disease Model Acute monocytic leukemia [ICD-11:2A60]
Model Name Human acute monocytic leukemia cell lysate (THP-1)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 21 Protein Related to This Bioclass
Target ID Target Name Binding Sites
 LDTP05069  Actin, alpha cardiac muscle 1 (ACTC1) K20
 LDTP05069  Actin, alpha cardiac muscle 1 (ACTC1) R314
 LDTP05069  Actin, alpha cardiac muscle 1 (ACTC1) K240
 LDTP05069  Actin, alpha cardiac muscle 1 (ACTC1) R41
 LDTP04876  Actin, cytoplasmic 1 (ACTB) K238
 LDTP04876  Actin, cytoplasmic 1 (ACTB) R312
 LDTP04876  Actin, cytoplasmic 1 (ACTB) R95
 LDTP04876  Actin, cytoplasmic 1 (ACTB) K18
 LDTP04876  Actin, cytoplasmic 1 (ACTB) R39
 LDTP05071  Elongation factor 1-alpha 1 (EEF1A1) R321
 LDTP05071  Elongation factor 1-alpha 1 (EEF1A1) K395
 LDTP05071  Elongation factor 1-alpha 1 (EEF1A1) K219
 LDTP06569  Frataxin, mitochondrial (FXN) K80
 LDTP02038  Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) K117
 LDTP01790  Prothrombin (F2) R383
 LDTP01790  Prothrombin (F2) K599
 LDTP01790  Prothrombin (F2) K559
 LDTP02733  Pyruvate kinase PKM (PKM) K230
 LDTP05074  Tubulin alpha-1B chain (TUBA1B) K352
 LDTP05074  Tubulin alpha-1B chain (TUBA1B) R64
 LDTP05074  Tubulin alpha-1B chain (TUBA1B) R264
Transporter and channel
Click to Show/Hide to Show 5 Protein Related to This Bioclass
Target ID Target Name Binding Sites
 LDTP02262  Heat shock protein HSP 90-beta (HSP90AB1) K481
 LDTP05084  Hemoglobin subunit alpha (HBA1; HBA2) K17
 LDTP05084  Hemoglobin subunit alpha (HBA1; HBA2) R32
 LDTP05084  Hemoglobin subunit alpha (HBA1; HBA2) K41
 LDTP01999  Vitronectin (VTN) R197
Transcription factor
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Sites
 LDTP02343  High mobility group protein B1 (HMGB1) K128
Other
Click to Show/Hide to Show 27 Protein Related to This Bioclass
Target ID Target Name Binding Sites
 LDTP04931  10 kDa heat shock protein, mitochondrial (HSPE1) R20
 LDTP05294  Adenylyl cyclase-associated protein 1 (CAP1) R330
 LDTP05294  Adenylyl cyclase-associated protein 1 (CAP1) K377
 LDTP01963  Albumin (ALB) K286
 LDTP03244  Cofilin-1 (CFL1) K34
 LDTP03573  Coronin-1A (CORO1A) K324
 LDTP01922  Hemoglobin subunit epsilon (HBE1) R31
 LDTP06032  Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) K183
 LDTP03182  Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) K186
 LDTP02494  Histone H1.4 (H1-4) K110
 LDTP02494  Histone H1.4 (H1-4) K85
 LDTP02843  Histone H1.5 (H1-5) K88
 LDTP02843  Histone H1.5 (H1-5) K113
 LDTP02843  Histone H1.5 (H1-5) K66
 LDTP06628  Histone H2B type 2-E (H2BC21) K58
 LDTP06628  Histone H2B type 2-E (H2BC21) R100
 LDTP06628  Histone H2B type 2-E (H2BC21) K109
 LDTP04140  Large ribosomal subunit protein eL29 (RPL29) K92
 LDTP02990  Nucleolin (NCL) K486
 LDTP07634  POTE ankyrin domain family member E (POTEE) K938
 LDTP07634  POTE ankyrin domain family member E (POTEE) K718
 LDTP02218  Profilin-1 (PFN1) K26
 LDTP03775  RNA-binding protein FUS (FUS) K348
 LDTP05015  Small ribosomal subunit protein eS28 (RPS28) R20
 LDTP04970  Small ribosomal subunit protein uS11 (RPS14) K125
 LDTP04249  T-complex protein 1 subunit gamma (CCT3) K248
 LDTP02205  Tubulin beta chain (TUBB) R282

References

1 Unveiling the Multifaceted Capabilities of Endophytic Aspergillus flavus Isolated from Annona squamosa Fruit Peels against Staphylococcus Isolates and HCoV 229E-In Vitro and In Silico Investigations. Pharmaceuticals (Basel). 2024 May 19;17(5):656. doi: 10.3390/ph17050656.
Mass spectrometry data entry: PXD013019