Details of the Target

General Information of Target

Target ID LDTP19919
Target Name Programmed cell death protein 2-like (PDCD2L)
Gene Name PDCD2L
Gene ID 84306
Synonyms
Programmed cell death protein 2-like
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAKQKRKVPEVTEKKNKKLKKASAEGPLLGPEAAPSGEGAGSKGEAVLRPGLDAEPELSP
EEQRVLERKLKKERKKEERQRLREAGLVAQHPPARRSGAELALDYLCRWAQKHKNWRFQK
TRQTWLLLHMYDSDKVPDEHFSTLLAYLEGLQGRARELTVQKAEALMRELDEEGSDPPLP
GRAQRIRQVLQLLS
Target Bioclass
Other
Function Over-expression suppresses AP1, CREB, NFAT, and NF-kB transcriptional activation, and delays cell cycle progression at S phase.
Uniprot ID
Q9BRP1
Ensemble ID
ENST00000246535.4
HGNC ID
HGNC:28194

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 16 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
BTD
 Probe Info  		C260(0.76)  LDD2101  [2]
DBIA
 Probe Info  		C100(0.96)  LDD0078  [3]
ATP probe
 Probe Info  		N.A.  LDD0199  [4]
4-Iodoacetamidophenylacetylene
 Probe Info  		C260(0.00); C49(0.00); C100(0.00)  LDD0038  [5]
IA-alkyne
 Probe Info  		C49(0.00); C260(0.00); C100(0.00)  LDD0036  [5]
Lodoacetamide azide
 Probe Info  		C260(0.00); C100(0.00); C49(0.00)  LDD0037  [5]
TFBX
 Probe Info  		N.A.  LDD0027  [6]
WYneN
 Probe Info  		N.A.  LDD0021  [7]
IPM
 Probe Info  		C100(0.00); C85(0.00); C80(0.00)  LDD0005  [7]
Phosphinate-6
 Probe Info  		C85(0.00); C80(0.00)  LDD0018  [8]
Acrolein
 Probe Info  		N.A.  LDD0217  [9]
Methacrolein
 Probe Info  		N.A.  LDD0218  [9]
W1
 Probe Info  		N.A.  LDD0236  [10]
AOyne
 Probe Info  		14.70  LDD0443  [11]
NAIA_5
 Probe Info  		C260(0.00); C49(0.00)  LDD2223  [12]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C260(1.06)  LDD2117  [2]
 LDCM0026  4SU-RNA+native RNA HEK-293T C100(2.45)  LDD0372  [13]
 LDCM0214  AC1 HCT 116 C100(1.05); C260(0.88); C278(0.52); C289(0.63)  LDD0531  [3]
 LDCM0215  AC10 HCT 116 C100(0.87); C260(1.18); C278(0.85); C289(0.85)  LDD0532  [3]
 LDCM0216  AC100 HCT 116 C100(0.87); C260(1.15); C278(0.58); C289(0.58)  LDD0533  [3]
 LDCM0217  AC101 HCT 116 C100(0.89); C260(1.11); C278(0.44); C289(0.44)  LDD0534  [3]
 LDCM0218  AC102 HCT 116 C100(0.89); C260(1.04); C278(0.66); C289(0.66)  LDD0535  [3]
 LDCM0219  AC103 HCT 116 C100(0.88); C260(0.92); C278(0.30); C289(0.30)  LDD0536  [3]
 LDCM0220  AC104 HCT 116 C100(0.98); C260(1.71); C278(0.38); C289(0.38)  LDD0537  [3]
 LDCM0221  AC105 HCT 116 C100(0.92); C260(1.19); C278(0.50); C289(0.50)  LDD0538  [3]
 LDCM0222  AC106 HCT 116 C100(1.00); C260(0.87); C278(0.42); C289(0.42)  LDD0539  [3]
 LDCM0223  AC107 HCT 116 C100(0.93); C260(1.06); C278(0.49); C289(0.48)  LDD0540  [3]
 LDCM0224  AC108 HCT 116 C100(0.86); C260(1.04); C278(0.34); C289(0.30)  LDD0541  [3]
 LDCM0225  AC109 HCT 116 C100(0.99); C260(1.49); C278(0.35); C289(0.34)  LDD0542  [3]
 LDCM0226  AC11 HCT 116 C100(0.75); C260(1.40); C278(0.73); C289(0.73)  LDD0543  [3]
 LDCM0227  AC110 HCT 116 C100(0.95); C260(1.01); C278(0.34); C289(0.39)  LDD0544  [3]
 LDCM0228  AC111 HCT 116 C100(0.95); C260(1.09); C278(0.41); C289(0.46)  LDD0545  [3]
 LDCM0229  AC112 HCT 116 C100(1.07); C260(0.89); C278(0.44); C289(0.63)  LDD0546  [3]
 LDCM0230  AC113 HCT 116 C100(1.04); C260(1.02); C80(1.37); C82(1.29)  LDD0547  [3]
 LDCM0231  AC114 HCT 116 C100(0.99); C260(1.38); C80(0.95); C82(0.98)  LDD0548  [3]
 LDCM0232  AC115 HCT 116 C100(1.02); C260(1.16); C80(0.88); C82(0.98)  LDD0549  [3]
 LDCM0233  AC116 HCT 116 C100(1.05); C260(1.02); C80(0.88); C82(0.98)  LDD0550  [3]
 LDCM0234  AC117 HCT 116 C100(1.01); C260(1.02); C80(0.92); C82(0.93)  LDD0551  [3]
 LDCM0235  AC118 HCT 116 C100(0.93); C260(1.16); C80(1.09); C82(1.11)  LDD0552  [3]
 LDCM0236  AC119 HCT 116 C100(1.05); C260(1.47); C80(1.15); C82(1.04)  LDD0553  [3]
 LDCM0237  AC12 HCT 116 C100(0.74); C260(1.31); C278(1.08); C289(1.08)  LDD0554  [3]
 LDCM0238  AC120 HCT 116 C100(0.93); C260(1.06); C80(1.00); C82(1.03)  LDD0555  [3]
 LDCM0239  AC121 HCT 116 C100(0.90); C260(1.08); C80(1.11); C82(1.10)  LDD0556  [3]
 LDCM0240  AC122 HCT 116 C100(1.17); C260(1.06); C80(0.84); C82(0.82)  LDD0557  [3]
 LDCM0241  AC123 HCT 116 C100(0.88); C260(1.56); C80(1.01); C82(1.11)  LDD0558  [3]
 LDCM0242  AC124 HCT 116 C100(0.90); C260(0.97); C80(1.25); C82(1.17)  LDD0559  [3]
 LDCM0243  AC125 HCT 116 C100(0.93); C260(1.47); C80(1.12); C82(1.10)  LDD0560  [3]
 LDCM0244  AC126 HCT 116 C100(1.00); C260(1.35); C80(0.89); C82(0.98)  LDD0561  [3]
 LDCM0245  AC127 HCT 116 C100(0.97); C260(1.47); C80(0.81); C82(0.84)  LDD0562  [3]
 LDCM0246  AC128 HCT 116 C100(0.90); C80(0.85); C82(0.85); C85(0.87)  LDD0563  [3]
 LDCM0247  AC129 HCT 116 C100(1.06); C80(1.20); C82(1.20); C85(1.18)  LDD0564  [3]
 LDCM0249  AC130 HCT 116 C100(1.09); C80(0.79); C82(0.75); C85(0.80)  LDD0566  [3]
 LDCM0250  AC131 HCT 116 C100(0.99); C80(1.19); C82(1.16); C85(1.20)  LDD0567  [3]
 LDCM0251  AC132 HCT 116 C100(0.99); C80(0.95); C82(1.00); C85(0.97)  LDD0568  [3]
 LDCM0252  AC133 HCT 116 C100(1.09); C80(0.81); C82(0.78); C85(0.79)  LDD0569  [3]
 LDCM0253  AC134 HCT 116 C100(0.96); C80(0.80); C82(0.89); C85(0.86)  LDD0570  [3]
 LDCM0254  AC135 HCT 116 C100(0.98); C80(0.80); C82(0.86); C85(0.84)  LDD0571  [3]
 LDCM0255  AC136 HCT 116 C100(1.01); C80(0.86); C82(0.87); C85(0.87)  LDD0572  [3]
 LDCM0256  AC137 HCT 116 C100(0.95); C80(0.93); C82(1.00); C85(0.95)  LDD0573  [3]
 LDCM0257  AC138 HCT 116 C100(0.86); C80(0.90); C82(0.90); C85(0.91)  LDD0574  [3]
 LDCM0258  AC139 HCT 116 C100(0.96); C80(0.86); C82(0.87); C85(0.89)  LDD0575  [3]
 LDCM0259  AC14 HCT 116 C100(0.66); C260(1.17); C278(0.59); C289(0.59)  LDD0576  [3]
 LDCM0260  AC140 HCT 116 C100(0.98); C80(0.85); C82(0.90); C85(0.89)  LDD0577  [3]
 LDCM0261  AC141 HCT 116 C100(1.13); C80(0.92); C82(0.94); C85(0.94)  LDD0578  [3]
 LDCM0262  AC142 HCT 116 C100(0.98); C80(0.87); C82(0.86); C85(0.86)  LDD0579  [3]
 LDCM0263  AC143 HCT 116 C82(0.89); C80(0.95); C85(0.98); C260(1.02)  LDD0580  [3]
 LDCM0264  AC144 HCT 116 C278(0.44); C289(0.44); C292(0.44); C260(0.87)  LDD0581  [3]
 LDCM0265  AC145 HCT 116 C278(0.49); C289(0.49); C292(0.49); C82(1.12)  LDD0582  [3]
 LDCM0266  AC146 HCT 116 C278(0.31); C289(0.31); C292(0.31); C80(0.88)  LDD0583  [3]
 LDCM0267  AC147 HCT 116 C278(0.48); C289(0.48); C292(0.48); C100(0.91)  LDD0584  [3]
 LDCM0268  AC148 HCT 116 C278(0.26); C289(0.26); C292(0.26); C80(0.96)  LDD0585  [3]
 LDCM0269  AC149 HCT 116 C278(0.33); C289(0.33); C292(0.33); C80(0.67)  LDD0586  [3]
 LDCM0270  AC15 HCT 116 C100(0.68); C82(0.79); C80(0.83); C85(0.84)  LDD0587  [3]
 LDCM0271  AC150 HCT 116 C100(0.86); C80(0.90); C82(1.00); C85(1.03)  LDD0588  [3]
 LDCM0272  AC151 HCT 116 C278(0.68); C289(0.68); C292(0.68); C80(0.74)  LDD0589  [3]
 LDCM0273  AC152 HCT 116 C278(0.41); C289(0.41); C292(0.41); C80(0.86)  LDD0590  [3]
 LDCM0274  AC153 HCT 116 C278(0.25); C289(0.25); C292(0.25); C80(0.83)  LDD0591  [3]
 LDCM0621  AC154 HCT 116 C100(1.13); C260(1.38); C278(0.46); C289(0.46)  LDD2158  [3]
 LDCM0622  AC155 HCT 116 C100(1.23); C260(1.19); C278(0.89); C289(0.89)  LDD2159  [3]
 LDCM0623  AC156 HCT 116 C100(0.99); C260(1.17); C278(1.01); C289(1.01)  LDD2160  [3]
 LDCM0624  AC157 HCT 116 C100(1.13); C260(1.17); C278(1.76); C289(1.76)  LDD2161  [3]
 LDCM0276  AC17 HCT 116 C85(0.84); C80(0.86); C82(1.01); C100(1.04)  LDD0593  [3]
 LDCM0277  AC18 HCT 116 C85(0.71); C80(0.71); C82(0.82); C260(1.09)  LDD0594  [3]
 LDCM0278  AC19 HCT 116 C80(0.93); C85(0.94); C260(0.94); C82(1.09)  LDD0595  [3]
 LDCM0279  AC2 HCT 116 C260(0.74); C292(0.85); C278(0.90); C289(0.95)  LDD0596  [3]
 LDCM0280  AC20 HCT 116 C260(0.93); C100(1.10); C85(1.11); C80(1.11)  LDD0597  [3]
 LDCM0281  AC21 HCT 116 C100(0.92); C85(0.94); C80(0.97); C82(1.00)  LDD0598  [3]
 LDCM0282  AC22 HCT 116 C80(0.88); C85(0.89); C82(0.94); C260(1.02)  LDD0599  [3]
 LDCM0283  AC23 HCT 116 C80(0.92); C85(0.93); C82(0.96); C260(0.99)  LDD0600  [3]
 LDCM0284  AC24 HCT 116 C100(1.05); C260(1.13); C80(1.22); C85(1.25)  LDD0601  [3]
 LDCM0285  AC25 HCT 116 C82(0.92); C85(0.94); C80(1.01); C260(1.05)  LDD0602  [3]
 LDCM0286  AC26 HCT 116 C82(0.90); C85(0.91); C80(1.02); C100(1.32)  LDD0603  [3]
 LDCM0287  AC27 HCT 116 C82(0.92); C85(0.96); C80(1.07); C100(1.36)  LDD0604  [3]
 LDCM0288  AC28 HCT 116 C85(0.91); C82(0.96); C80(1.05); C260(1.19)  LDD0605  [3]
 LDCM0289  AC29 HCT 116 C85(0.98); C82(0.99); C80(1.11); C260(1.21)  LDD0606  [3]
 LDCM0290  AC3 HCT 116 C292(0.80); C260(0.86); C82(0.90); C278(0.92)  LDD0607  [3]
 LDCM0291  AC30 HCT 116 C85(0.79); C82(0.85); C80(0.87); C260(1.04)  LDD0608  [3]
 LDCM0292  AC31 HCT 116 C82(0.86); C85(0.88); C80(0.97); C260(1.01)  LDD0609  [3]
 LDCM0293  AC32 HCT 116 C85(0.80); C82(0.88); C80(0.93); C260(1.14)  LDD0610  [3]
 LDCM0294  AC33 HCT 116 C85(1.00); C82(1.01); C80(1.05); C260(1.23)  LDD0611  [3]
 LDCM0295  AC34 HCT 116 C85(0.87); C82(0.88); C80(0.89); C260(1.17)  LDD0612  [3]
 LDCM0296  AC35 HCT 116 C100(0.92); C278(1.02); C292(1.02); C82(1.13)  LDD0613  [3]
 LDCM0297  AC36 HCT 116 C100(0.86); C260(0.99); C85(1.28); C278(1.35)  LDD0614  [3]
 LDCM0298  AC37 HCT 116 C100(0.90); C85(1.24); C260(1.24); C82(1.25)  LDD0615  [3]
 LDCM0299  AC38 HCT 116 C100(0.86); C278(1.08); C292(1.08); C85(1.13)  LDD0616  [3]
 LDCM0300  AC39 HCT 116 C100(0.88); C85(1.06); C80(1.08); C82(1.10)  LDD0617  [3]
 LDCM0301  AC4 HCT 116 C292(0.69); C278(0.81); C82(0.98); C260(1.06)  LDD0618  [3]
 LDCM0302  AC40 HCT 116 C85(0.92); C82(1.00); C80(1.01); C100(1.07)  LDD0619  [3]
 LDCM0303  AC41 HCT 116 C100(0.99); C85(1.00); C80(1.04); C82(1.07)  LDD0620  [3]
 LDCM0304  AC42 HCT 116 C100(0.90); C80(0.98); C85(0.98); C82(1.03)  LDD0621  [3]
 LDCM0305  AC43 HCT 116 C85(0.78); C80(0.79); C82(0.82); C278(0.93)  LDD0622  [3]
 LDCM0306  AC44 HCT 116 C100(0.95); C85(1.02); C82(1.03); C80(1.07)  LDD0623  [3]
 LDCM0307  AC45 HCT 116 C278(0.83); C292(0.83); C85(0.89); C82(0.94)  LDD0624  [3]
 LDCM0308  AC46 HCT 116 C80(0.91); C82(0.93); C85(0.97); C100(1.14)  LDD0625  [3]
 LDCM0309  AC47 HCT 116 C82(0.91); C85(0.92); C80(0.96); C100(1.09)  LDD0626  [3]
 LDCM0310  AC48 HCT 116 C85(0.64); C82(0.65); C80(0.72); C278(0.78)  LDD0627  [3]
 LDCM0311  AC49 HCT 116 C85(0.78); C80(0.79); C82(0.81); C260(0.93)  LDD0628  [3]
 LDCM0312  AC5 HCT 116 C292(0.76); C278(0.80); C82(0.81); C260(0.92)  LDD0629  [3]
 LDCM0313  AC50 HCT 116 C85(0.77); C82(0.78); C80(0.81); C260(0.94)  LDD0630  [3]
 LDCM0314  AC51 HCT 116 C100(0.87); C85(0.93); C82(0.96); C80(0.97)  LDD0631  [3]
 LDCM0315  AC52 HCT 116 C80(0.88); C85(0.91); C82(0.94); C260(1.00)  LDD0632  [3]
 LDCM0316  AC53 HCT 116 C80(0.85); C85(0.85); C82(0.85); C260(0.99)  LDD0633  [3]
 LDCM0317  AC54 HCT 116 C85(0.97); C80(1.00); C82(1.02); C260(1.03)  LDD0634  [3]
 LDCM0318  AC55 HCT 116 C80(0.77); C85(0.80); C82(0.80); C278(1.09)  LDD0635  [3]
 LDCM0319  AC56 HCT 116 C85(0.71); C80(0.73); C82(0.75); C278(0.94)  LDD0636  [3]
 LDCM0320  AC57 HCT 116 C278(0.25); C289(0.25); C292(0.25); C85(0.65)  LDD0637  [3]
 LDCM0321  AC58 HCT 116 C278(0.21); C289(0.21); C292(0.21); C85(0.63)  LDD0638  [3]
 LDCM0322  AC59 HCT 116 C278(0.34); C289(0.34); C292(0.34); C85(0.62)  LDD0639  [3]
 LDCM0323  AC6 HCT 116 C100(0.82); C80(0.96); C278(0.98); C289(0.98)  LDD0640  [3]
 LDCM0324  AC60 HCT 116 C278(0.17); C289(0.17); C292(0.17); C85(0.47)  LDD0641  [3]
 LDCM0325  AC61 HCT 116 C278(0.15); C289(0.15); C292(0.15); C85(0.51)  LDD0642  [3]
 LDCM0326  AC62 HCT 116 C278(0.22); C289(0.22); C292(0.22); C85(0.66)  LDD0643  [3]
 LDCM0327  AC63 HCT 116 C278(0.18); C289(0.18); C292(0.18); C85(0.54)  LDD0644  [3]
 LDCM0328  AC64 HCT 116 C278(0.21); C289(0.21); C292(0.21); C85(0.54)  LDD0645  [3]
 LDCM0329  AC65 HCT 116 C278(0.22); C289(0.22); C292(0.22); C85(0.59)  LDD0646  [3]
 LDCM0330  AC66 HCT 116 C278(0.21); C289(0.21); C292(0.21); C80(0.61)  LDD0647  [3]
 LDCM0331  AC67 HCT 116 C278(0.13); C289(0.13); C292(0.13); C85(0.46)  LDD0648  [3]
 LDCM0332  AC68 HCT 116 C82(0.85); C100(0.89); C85(0.90); C80(1.03)  LDD0649  [3]
 LDCM0333  AC69 HCT 116 C100(0.78); C260(0.85); C82(1.06); C85(1.12)  LDD0650  [3]
 LDCM0334  AC7 HCT 116 C80(0.77); C82(0.79); C85(0.79); C100(0.90)  LDD0651  [3]
 LDCM0335  AC70 HCT 116 C82(0.92); C260(0.93); C100(0.98); C85(1.01)  LDD0652  [3]
 LDCM0336  AC71 HCT 116 C100(0.83); C260(0.99); C82(1.03); C85(1.09)  LDD0653  [3]
 LDCM0337  AC72 HCT 116 C82(0.78); C85(0.86); C100(0.90); C80(0.98)  LDD0654  [3]
 LDCM0338  AC73 HCT 116 C82(0.84); C100(0.89); C85(0.89); C80(1.15)  LDD0655  [3]
 LDCM0339  AC74 HCT 116 C100(0.77); C82(1.03); C85(1.07); C260(1.08)  LDD0656  [3]
 LDCM0340  AC75 HCT 116 C260(0.88); C82(0.91); C85(0.97); C100(0.98)  LDD0657  [3]
 LDCM0341  AC76 HCT 116 C100(0.82); C82(0.95); C85(1.00); C80(1.12)  LDD0658  [3]
 LDCM0342  AC77 HCT 116 C82(0.89); C100(0.89); C85(0.96); C260(1.06)  LDD0659  [3]
 LDCM0343  AC78 HCT 116 C82(0.88); C100(0.90); C85(0.94); C260(1.01)  LDD0660  [3]
 LDCM0344  AC79 HCT 116 C260(0.93); C100(1.00); C82(1.15); C85(1.20)  LDD0661  [3]
 LDCM0345  AC8 HCT 116 C80(0.74); C82(0.76); C85(0.77); C100(0.90)  LDD0662  [3]
 LDCM0346  AC80 HCT 116 C100(0.91); C260(0.92); C80(0.96); C82(0.99)  LDD0663  [3]
 LDCM0347  AC81 HCT 116 C100(0.84); C82(0.98); C85(1.05); C260(1.20)  LDD0664  [3]
 LDCM0348  AC82 HCT 116 C100(0.84); C82(0.90); C85(0.96); C260(1.03)  LDD0665  [3]
 LDCM0349  AC83 HCT 116 C278(0.48); C289(0.48); C292(0.48); C80(0.57)  LDD0666  [3]
 LDCM0350  AC84 HCT 116 C278(0.59); C289(0.59); C292(0.59); C80(0.62)  LDD0667  [3]
 LDCM0351  AC85 HCT 116 C278(0.52); C289(0.52); C292(0.52); C80(0.61)  LDD0668  [3]
 LDCM0352  AC86 HCT 116 C260(0.79); C80(0.93); C85(0.94); C278(1.00)  LDD0669  [3]
 LDCM0353  AC87 HCT 116 C260(0.80); C80(0.81); C85(0.85); C82(0.87)  LDD0670  [3]
 LDCM0354  AC88 HCT 116 C260(0.88); C278(0.97); C289(0.97); C292(0.97)  LDD0671  [3]
 LDCM0355  AC89 HCT 116 C80(0.69); C85(0.70); C278(0.70); C289(0.70)  LDD0672  [3]
 LDCM0357  AC90 HCT 116 C260(0.81); C80(1.14); C85(1.16); C82(1.19)  LDD0674  [3]
 LDCM0358  AC91 HCT 116 C278(0.62); C289(0.62); C292(0.62); C80(0.72)  LDD0675  [3]
 LDCM0359  AC92 HCT 116 C278(0.64); C289(0.64); C292(0.64); C80(0.71)  LDD0676  [3]
 LDCM0360  AC93 HCT 116 C80(0.77); C260(0.78); C85(0.79); C278(0.79)  LDD0677  [3]
 LDCM0361  AC94 HCT 116 C278(0.62); C289(0.62); C292(0.62); C85(0.72)  LDD0678  [3]
 LDCM0362  AC95 HCT 116 C278(0.44); C289(0.44); C292(0.44); C80(0.60)  LDD0679  [3]
 LDCM0363  AC96 HCT 116 C278(0.61); C289(0.61); C292(0.61); C85(0.79)  LDD0680  [3]
 LDCM0364  AC97 HCT 116 C80(0.69); C85(0.73); C82(0.85); C260(0.86)  LDD0681  [3]
 LDCM0365  AC98 HCT 116 C278(0.12); C289(0.12); C292(0.12); C85(0.44)  LDD0682  [3]
 LDCM0366  AC99 HCT 116 C278(0.78); C289(0.78); C292(0.78); C80(0.88)  LDD0683  [3]
 LDCM0248  AKOS034007472 HCT 116 C100(0.73); C260(1.10); C278(1.37); C289(1.37)  LDD0565  [3]
 LDCM0356  AKOS034007680 HCT 116 C100(0.72); C82(0.84); C80(0.85); C85(0.85)  LDD0673  [3]
 LDCM0275  AKOS034007705 HCT 116 C278(0.62); C289(0.62); C80(0.64); C82(0.66)  LDD0592  [3]
 LDCM0156  Aniline NCI-H1299 13.29  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C100(0.96)  LDD0078  [3]
 LDCM0630  CCW28-3 231MFP C278(1.48)  LDD2214  [14]
 LDCM0108  Chloroacetamide HeLa C260(0.00); C100(0.00)  LDD0222  [9]
 LDCM0367  CL1 HCT 116 C292(0.80); C278(0.95); C289(0.96); C260(0.99)  LDD0684  [3]
 LDCM0368  CL10 HCT 116 C289(0.32); C292(0.32); C278(0.58); C80(0.75)  LDD0685  [3]
 LDCM0369  CL100 HCT 116 C292(0.60); C278(0.67); C260(0.77); C289(0.87)  LDD0686  [3]
 LDCM0370  CL101 HCT 116 C278(0.69); C289(0.69); C100(0.82); C82(0.83)  LDD0687  [3]
 LDCM0371  CL102 HCT 116 C100(0.79); C278(0.95); C289(0.95); C260(1.00)  LDD0688  [3]
 LDCM0372  CL103 HCT 116 C100(0.75); C82(1.01); C80(1.08); C85(1.11)  LDD0689  [3]
 LDCM0373  CL104 HCT 116 C100(0.70); C82(0.84); C80(0.89); C85(0.91)  LDD0690  [3]
 LDCM0374  CL105 HCT 116 C100(0.89); C85(0.93); C260(0.95); C80(0.95)  LDD0691  [3]
 LDCM0375  CL106 HCT 116 C80(0.58); C85(0.59); C82(0.86); C260(0.88)  LDD0692  [3]
 LDCM0376  CL107 HCT 116 C80(0.63); C85(0.66); C82(0.88); C260(1.01)  LDD0693  [3]
 LDCM0377  CL108 HCT 116 C80(0.72); C85(0.73); C100(0.97); C82(1.05)  LDD0694  [3]
 LDCM0378  CL109 HCT 116 C80(0.74); C85(0.77); C260(0.96); C82(1.00)  LDD0695  [3]
 LDCM0379  CL11 HCT 116 C289(0.35); C292(0.35); C278(0.47); C80(0.75)  LDD0696  [3]
 LDCM0380  CL110 HCT 116 C100(0.88); C80(0.89); C85(0.90); C260(1.00)  LDD0697  [3]
 LDCM0381  CL111 HCT 116 C80(0.79); C85(0.81); C82(0.92); C260(1.00)  LDD0698  [3]
 LDCM0382  CL112 HCT 116 C82(1.01); C85(1.04); C260(1.10); C80(1.15)  LDD0699  [3]
 LDCM0383  CL113 HCT 116 C82(0.86); C85(0.88); C80(0.98); C260(1.11)  LDD0700  [3]
 LDCM0384  CL114 HCT 116 C85(1.06); C82(1.11); C100(1.14); C80(1.15)  LDD0701  [3]
 LDCM0385  CL115 HCT 116 C82(1.00); C85(1.02); C80(1.02); C260(1.29)  LDD0702  [3]
 LDCM0386  CL116 HCT 116 C85(0.87); C82(0.87); C80(0.89); C260(1.21)  LDD0703  [3]
 LDCM0387  CL117 HCT 116 C278(0.79); C292(0.79); C80(0.79); C85(0.96)  LDD0704  [3]
 LDCM0388  CL118 HCT 116 C100(0.93); C85(1.07); C278(1.12); C292(1.12)  LDD0705  [3]
 LDCM0389  CL119 HCT 116 C278(0.85); C292(0.85); C85(0.94); C100(0.99)  LDD0706  [3]
 LDCM0390  CL12 HCT 116 C292(0.41); C289(0.44); C278(0.53); C80(0.82)  LDD0707  [3]
 LDCM0391  CL120 HCT 116 C85(0.93); C100(1.01); C82(1.02); C80(1.04)  LDD0708  [3]
 LDCM0392  CL121 HCT 116 C260(1.04); C278(1.08); C292(1.08); C80(1.35)  LDD0709  [3]
 LDCM0393  CL122 HCT 116 C80(0.75); C82(0.78); C85(0.79); C260(0.87)  LDD0710  [3]
 LDCM0394  CL123 HCT 116 C100(1.01); C260(1.02); C85(1.05); C82(1.08)  LDD0711  [3]
 LDCM0395  CL124 HCT 116 C85(0.89); C80(0.89); C82(0.94); C260(1.02)  LDD0712  [3]
 LDCM0396  CL125 HCT 116 C278(0.50); C289(0.50); C292(0.50); C100(0.96)  LDD0713  [3]
 LDCM0397  CL126 HCT 116 C278(0.48); C289(0.48); C292(0.48); C80(0.94)  LDD0714  [3]
 LDCM0398  CL127 HCT 116 C278(0.42); C289(0.42); C292(0.42); C85(0.80)  LDD0715  [3]
 LDCM0399  CL128 HCT 116 C278(0.35); C289(0.35); C292(0.35); C85(0.70)  LDD0716  [3]
 LDCM0400  CL13 HCT 116 C289(0.27); C292(0.27); C278(0.43); C80(0.69)  LDD0717  [3]
 LDCM0401  CL14 HCT 116 C289(0.62); C292(0.64); C278(0.72); C100(0.91)  LDD0718  [3]
 LDCM0402  CL15 HCT 116 C292(0.29); C289(0.29); C278(0.45); C100(0.85)  LDD0719  [3]
 LDCM0403  CL16 HCT 116 C289(0.68); C85(0.85); C292(0.86); C80(0.89)  LDD0720  [3]
 LDCM0404  CL17 HCT 116 C289(0.51); C292(0.53); C278(0.55); C260(0.70)  LDD0721  [3]
 LDCM0405  CL18 HCT 116 C289(0.23); C292(0.30); C278(0.34); C80(0.46)  LDD0722  [3]
 LDCM0406  CL19 HCT 116 C289(0.36); C292(0.42); C278(0.48); C85(0.68)  LDD0723  [3]
 LDCM0407  CL2 HCT 116 C292(0.76); C278(0.77); C289(0.85); C100(0.98)  LDD0724  [3]
 LDCM0408  CL20 HCT 116 C289(0.57); C85(0.64); C292(0.64); C278(0.71)  LDD0725  [3]
 LDCM0409  CL21 HCT 116 C289(0.39); C292(0.45); C278(0.52); C260(0.67)  LDD0726  [3]
 LDCM0410  CL22 HCT 116 C289(0.34); C292(0.39); C278(0.44); C80(0.62)  LDD0727  [3]
 LDCM0411  CL23 HCT 116 C289(0.53); C292(0.66); C80(0.69); C85(0.74)  LDD0728  [3]
 LDCM0412  CL24 HCT 116 C289(0.42); C292(0.46); C278(0.50); C80(0.67)  LDD0729  [3]
 LDCM0413  CL25 HCT 116 C100(1.00); C260(0.67); C278(0.57); C289(0.45)  LDD0730  [3]
 LDCM0414  CL26 HCT 116 C100(0.91); C260(0.92); C278(0.69); C289(0.50)  LDD0731  [3]
 LDCM0415  CL27 HCT 116 C100(1.22); C260(0.82); C278(0.70); C289(0.55)  LDD0732  [3]
 LDCM0416  CL28 HCT 116 C100(1.18); C260(0.66); C278(0.46); C289(0.38)  LDD0733  [3]
 LDCM0417  CL29 HCT 116 C100(1.33); C260(0.96); C278(0.55); C289(0.43)  LDD0734  [3]
 LDCM0418  CL3 HCT 116 C100(0.88); C260(0.95); C278(0.73); C289(0.66)  LDD0735  [3]
 LDCM0419  CL30 HCT 116 C100(1.23); C260(0.66); C278(0.56); C289(0.52)  LDD0736  [3]
 LDCM0420  CL31 HCT 116 C100(0.97); C260(0.98); C80(0.98); C82(1.13)  LDD0737  [3]
 LDCM0421  CL32 HCT 116 C100(1.13); C260(1.14); C80(0.59); C82(0.94)  LDD0738  [3]
 LDCM0422  CL33 HCT 116 C100(1.12); C260(1.72); C80(0.87); C82(1.34)  LDD0739  [3]
 LDCM0423  CL34 HCT 116 C100(1.00); C260(1.98); C80(0.73); C82(1.32)  LDD0740  [3]
 LDCM0424  CL35 HCT 116 C100(1.26); C260(1.37); C80(0.77); C82(1.30)  LDD0741  [3]
 LDCM0425  CL36 HCT 116 C100(1.11); C260(1.08); C80(0.82); C82(1.15)  LDD0742  [3]
 LDCM0426  CL37 HCT 116 C100(1.16); C260(1.83); C80(0.74); C82(1.12)  LDD0743  [3]
 LDCM0428  CL39 HCT 116 C100(1.12); C260(1.13); C80(0.91); C82(1.17)  LDD0745  [3]
 LDCM0429  CL4 HCT 116 C100(1.03); C260(1.02); C278(0.67); C289(0.63)  LDD0746  [3]
 LDCM0430  CL40 HCT 116 C100(0.99); C260(1.07); C80(0.81); C82(1.15)  LDD0747  [3]
 LDCM0431  CL41 HCT 116 C100(1.06); C260(1.05); C80(0.88); C82(1.23)  LDD0748  [3]
 LDCM0432  CL42 HCT 116 C100(0.91); C260(1.10); C80(0.88); C82(1.66)  LDD0749  [3]
 LDCM0433  CL43 HCT 116 C100(1.06); C260(1.83); C80(0.68); C82(1.19)  LDD0750  [3]
 LDCM0434  CL44 HCT 116 C100(1.10); C260(1.16); C80(0.75); C82(1.10)  LDD0751  [3]
 LDCM0435  CL45 HCT 116 C100(1.09); C260(1.12); C80(0.77); C82(1.10)  LDD0752  [3]
 LDCM0436  CL46 HCT 116 C100(1.46); C278(1.06); C289(1.48); C292(1.48)  LDD0753  [3]
 LDCM0437  CL47 HCT 116 C100(1.00); C278(1.24); C289(1.65); C292(1.65)  LDD0754  [3]
 LDCM0438  CL48 HCT 116 C100(1.10); C278(1.61); C289(2.52); C292(2.52)  LDD0755  [3]
 LDCM0439  CL49 HCT 116 C100(1.03); C278(1.27); C289(1.11); C292(1.11)  LDD0756  [3]
 LDCM0440  CL5 HCT 116 C100(0.87); C260(0.95); C278(0.60); C289(0.58)  LDD0757  [3]
 LDCM0441  CL50 HCT 116 C100(0.94); C278(1.37); C289(1.99); C292(1.99)  LDD0758  [3]
 LDCM0442  CL51 HCT 116 C100(1.18); C278(1.22); C289(1.71); C292(1.71)  LDD0759  [3]
 LDCM0443  CL52 HCT 116 C100(1.36); C278(1.17); C289(1.58); C292(1.58)  LDD0760  [3]
 LDCM0444  CL53 HCT 116 C100(0.99); C278(1.41); C289(2.09); C292(2.09)  LDD0761  [3]
 LDCM0445  CL54 HCT 116 C100(1.26); C278(1.05); C289(1.33); C292(1.33)  LDD0762  [3]
 LDCM0446  CL55 HCT 116 C100(1.22); C278(1.37); C289(1.95); C292(1.95)  LDD0763  [3]
 LDCM0447  CL56 HCT 116 C100(1.16); C278(1.08); C289(1.04); C292(1.04)  LDD0764  [3]
 LDCM0448  CL57 HCT 116 C100(0.88); C278(1.34); C289(1.33); C292(1.33)  LDD0765  [3]
 LDCM0449  CL58 HCT 116 C100(1.10); C278(1.38); C289(1.67); C292(1.67)  LDD0766  [3]
 LDCM0450  CL59 HCT 116 C100(1.01); C278(0.95); C289(1.20); C292(1.20)  LDD0767  [3]
 LDCM0451  CL6 HCT 116 C100(0.87); C260(0.82); C278(0.43); C289(0.31)  LDD0768  [3]
 LDCM0452  CL60 HCT 116 C100(1.19); C278(1.35); C289(1.55); C292(1.55)  LDD0769  [3]
 LDCM0453  CL61 HCT 116 C100(0.93); C260(0.88); C278(0.80); C289(0.72)  LDD0770  [3]
 LDCM0454  CL62 HCT 116 C100(1.16); C260(1.13); C278(1.08); C289(0.84)  LDD0771  [3]
 LDCM0455  CL63 HCT 116 C100(1.22); C260(0.73); C278(0.81); C289(0.83)  LDD0772  [3]
 LDCM0456  CL64 HCT 116 C100(1.19); C260(0.68); C278(0.96); C289(0.61)  LDD0773  [3]
 LDCM0457  CL65 HCT 116 C100(0.98); C260(0.82); C278(0.78); C289(0.72)  LDD0774  [3]
 LDCM0458  CL66 HCT 116 C100(1.32); C260(0.88); C278(0.67); C289(0.44)  LDD0775  [3]
 LDCM0459  CL67 HCT 116 C100(1.10); C260(0.76); C278(0.76); C289(0.61)  LDD0776  [3]
 LDCM0460  CL68 HCT 116 C100(1.24); C260(0.44); C278(0.55); C289(0.37)  LDD0777  [3]
 LDCM0461  CL69 HCT 116 C100(0.96); C260(0.43); C278(0.46); C289(0.36)  LDD0778  [3]
 LDCM0462  CL7 HCT 116 C100(1.00); C260(0.85); C278(0.50); C289(0.37)  LDD0779  [3]
 LDCM0463  CL70 HCT 116 C100(1.07); C260(0.75); C278(0.62); C289(0.65)  LDD0780  [3]
 LDCM0464  CL71 HCT 116 C100(1.17); C260(0.67); C278(1.01); C289(0.89)  LDD0781  [3]
 LDCM0465  CL72 HCT 116 C100(0.95); C260(1.07); C278(1.28); C289(0.89)  LDD0782  [3]
 LDCM0466  CL73 HCT 116 C100(1.12); C260(0.78); C278(0.77); C289(0.58)  LDD0783  [3]
 LDCM0467  CL74 HCT 116 C100(1.02); C260(0.74); C278(0.90); C289(0.64)  LDD0784  [3]
 LDCM0469  CL76 HCT 116 C100(0.92); C260(0.94); C278(0.57); C289(0.65)  LDD0786  [3]
 LDCM0470  CL77 HCT 116 C100(0.86); C260(0.99); C278(0.81); C289(0.83)  LDD0787  [3]
 LDCM0471  CL78 HCT 116 C100(0.95); C260(1.06); C278(1.04); C289(1.09)  LDD0788  [3]
 LDCM0472  CL79 HCT 116 C100(0.98); C260(0.99); C278(0.65); C289(0.69)  LDD0789  [3]
 LDCM0473  CL8 HCT 116 C100(0.87); C260(0.87); C278(0.53); C289(0.43)  LDD0790  [3]
 LDCM0474  CL80 HCT 116 C100(0.97); C260(0.72); C278(0.42); C289(0.40)  LDD0791  [3]
 LDCM0475  CL81 HCT 116 C100(0.93); C260(1.04); C278(0.89); C289(0.99)  LDD0792  [3]
 LDCM0476  CL82 HCT 116 C100(0.92); C260(0.93); C278(0.55); C289(0.48)  LDD0793  [3]
 LDCM0477  CL83 HCT 116 C100(0.95); C260(0.88); C278(0.69); C289(0.59)  LDD0794  [3]
 LDCM0478  CL84 HCT 116 C100(0.96); C260(0.90); C278(0.56); C289(0.52)  LDD0795  [3]
 LDCM0479  CL85 HCT 116 C100(0.97); C260(1.08); C278(1.07); C289(0.92)  LDD0796  [3]
 LDCM0480  CL86 HCT 116 C100(0.89); C260(1.12); C278(1.07); C289(0.93)  LDD0797  [3]
 LDCM0481  CL87 HCT 116 C100(0.97); C260(1.24); C278(0.77); C289(0.86)  LDD0798  [3]
 LDCM0482  CL88 HCT 116 C100(0.91); C260(0.81); C278(0.67); C289(0.70)  LDD0799  [3]
 LDCM0483  CL89 HCT 116 C100(0.97); C260(0.83); C278(0.51); C289(0.44)  LDD0800  [3]
 LDCM0484  CL9 HCT 116 C100(0.98); C260(1.07); C278(0.62); C289(0.49)  LDD0801  [3]
 LDCM0485  CL90 HCT 116 C100(0.91); C260(1.32); C278(1.06); C289(0.96)  LDD0802  [3]
 LDCM0486  CL91 HCT 116 C100(1.16); C260(0.79); C278(0.88); C289(1.25)  LDD0803  [3]
 LDCM0487  CL92 HCT 116 C100(1.07); C260(0.82); C278(0.78); C289(0.97)  LDD0804  [3]
 LDCM0488  CL93 HCT 116 C100(1.06); C260(1.14); C278(0.96); C289(0.91)  LDD0805  [3]
 LDCM0489  CL94 HCT 116 C100(1.14); C260(0.69); C278(0.84); C289(1.03)  LDD0806  [3]
 LDCM0490  CL95 HCT 116 C100(1.11); C260(0.89); C278(0.88); C289(0.94)  LDD0807  [3]
 LDCM0491  CL96 HCT 116 C100(1.42); C260(0.95); C278(0.85); C289(0.93)  LDD0808  [3]
 LDCM0492  CL97 HCT 116 C100(1.16); C260(0.79); C278(0.78); C289(0.84)  LDD0809  [3]
 LDCM0493  CL98 HCT 116 C100(1.26); C260(0.88); C278(1.09); C289(1.30)  LDD0810  [3]
 LDCM0494  CL99 HCT 116 C100(1.22); C260(0.83); C278(0.70); C289(0.76)  LDD0811  [3]
 LDCM0495  E2913 HEK-293T C100(1.22); C278(1.00); C82(1.23)  LDD1698  [15]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C260(1.27); C100(1.19)  LDD1702  [2]
 LDCM0625  F8 Ramos C100(1.31); C49(1.42); C260(0.75)  LDD2187  [16]
 LDCM0572  Fragment10 Ramos C100(0.64); C49(0.39); C260(0.18)  LDD2189  [16]
 LDCM0573  Fragment11 Ramos C100(6.05); C49(0.87); C260(0.31)  LDD2190  [16]
 LDCM0574  Fragment12 Ramos C100(1.18); C49(0.26); C260(0.21)  LDD2191  [16]
 LDCM0575  Fragment13 Ramos C100(0.98); C49(0.82); C260(1.17)  LDD2192  [16]
 LDCM0576  Fragment14 Ramos C100(0.52); C49(0.57); C260(0.70)  LDD2193  [16]
 LDCM0579  Fragment20 Ramos C100(0.52); C49(0.31); C260(0.16)  LDD2194  [16]
 LDCM0580  Fragment21 Ramos C100(1.05); C49(0.70)  LDD2195  [16]
 LDCM0582  Fragment23 Ramos C100(1.31); C49(0.07); C260(0.39)  LDD2196  [16]
 LDCM0578  Fragment27 Ramos C100(1.00); C49(0.66); C260(1.08)  LDD2197  [16]
 LDCM0586  Fragment28 Ramos C100(0.65); C49(0.85); C260(0.24)  LDD2198  [16]
 LDCM0588  Fragment30 Ramos C100(1.53); C49(0.83); C260(0.79)  LDD2199  [16]
 LDCM0589  Fragment31 Ramos C100(1.32); C49(0.62); C260(0.81)  LDD2200  [16]
 LDCM0590  Fragment32 Ramos C100(3.04); C49(0.11); C260(0.18)  LDD2201  [16]
 LDCM0468  Fragment33 HCT 116 C100(1.02); C260(0.93); C278(0.84); C289(0.56)  LDD0785  [3]
 LDCM0596  Fragment38 Ramos C100(0.83); C49(0.57); C260(0.89)  LDD2203  [16]
 LDCM0566  Fragment4 Ramos C100(1.02); C49(0.91); C260(0.63)  LDD2184  [16]
 LDCM0427  Fragment51 HCT 116 C100(0.99); C260(1.44); C80(0.75); C82(1.50)  LDD0744  [3]
 LDCM0610  Fragment52 Ramos C100(1.02); C49(0.81); C260(0.50)  LDD2204  [16]
 LDCM0614  Fragment56 Ramos C100(1.47); C49(0.82)  LDD2205  [16]
 LDCM0569  Fragment7 Ramos C100(0.68); C49(0.51); C260(0.55)  LDD2186  [16]
 LDCM0571  Fragment9 Ramos C100(0.63); C49(0.41); C260(0.17)  LDD2188  [16]
 LDCM0022  KB02 HCT 116 C82(4.55); C278(1.35)  LDD0080  [3]
 LDCM0023  KB03 HCT 116 C82(1.65); C278(1.51)  LDD0081  [3]
 LDCM0024  KB05 HCT 116 C82(1.89); C278(1.55)  LDD0082  [3]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C260(0.76)  LDD2101  [2]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C260(1.23)  LDD2107  [2]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C260(0.59)  LDD2109  [2]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C260(1.10)  LDD2111  [2]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C260(0.48)  LDD2115  [2]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C260(0.84)  LDD2123  [2]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C260(0.78)  LDD2125  [2]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C260(1.04)  LDD2127  [2]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C260(1.01)  LDD2129  [2]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C260(0.78)  LDD2135  [2]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C260(1.39)  LDD2136  [2]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C260(1.03)  LDD2137  [2]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C260(0.89)  LDD2140  [2]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C260(0.81)  LDD2146  [2]
 LDCM0627  NUDT7-COV-1 HEK-293T C100(0.95); C100(0.49); C82(0.36)  LDD2206  [17]
 LDCM0628  OTUB2-COV-1 HEK-293T C82(0.78); C100(0.75)  LDD2207  [17]
 LDCM0131  RA190 MM1.R C260(1.46); C278(1.27)  LDD0304  [18]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Integrin beta-1-binding protein 2 (ITGB1BP2) . Q9UKP3

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
3 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
4 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
5 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
6 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
7 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
8 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
9 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
10 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
11 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
12 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
13 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
14 Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications. ACS Chem Biol. 2019 Nov 15;14(11):2430-2440. doi: 10.1021/acschembio.8b01083. Epub 2019 May 13.
15 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
16 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
17 Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening. J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22.
18 Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190. Cell Chem Biol. 2020 Nov 19;27(11):1371-1382.e6. doi: 10.1016/j.chembiol.2020.08.007. Epub 2020 Aug 27.