Details of the Target

General Information of Target

Target ID LDTP12068
Target Name Pleckstrin homology domain-containing family F member 2 (PLEKHF2)
Gene Name PLEKHF2
Gene ID 79666
Synonyms
ZFYVE18; Pleckstrin homology domain-containing family F member 2; PH domain-containing family F member 2; Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains; EAPF; PH and FYVE domain-containing protein 2; Phafin-2; Phafin2; Zinc finger FYVE domain-containing protein 18
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAENSVLTSTTGRTSLADSSIFDSKVTEISKENLLIGSTSYVEEEMPQIETRVILVQEAG
KQEELIKALKTIKIMEVPVIKIKESCPGKSDEKLIKSVINMDIKVGFVKMESVEEFEGLD
SPEFENVFVVTDFQDSVFNDLYKADCRVIGPPVVLNCSQKGEPLPFSCRPLYCTSMMNLV
LCFTGFRKKEELVRLVTLVHHMGGVIRKDFNSKVTHLVANCTQGEKFRVAVSLGTPIMKP
EWIYKAWERRNEQDFYAAVDDFRNEFKVPPFQDCILSFLGFSDEEKTNMEEMTEMQGGKY
LPLGDERCTHLVVEENIVKDLPFEPSKKLYVVKQEWFWGSIQMDARAGETMYLYEKANTP
ELKKSVSMLSLNTPNSNRKRRRLKETLAQLSRETDVSPFPPRKRPSAEHSLSIGSLLDIS
NTPESSINYGDTPKSCTKSSKSSTPVPSKQSARWQVAKELYQTESNYVNILATIIQLFQV
PLEEEGQRGGPILAPEEIKTIFGSIPDIFDVHTKIKDDLEDLIVNWDESKSIGDIFLKYS
KDLVKTYPPFVNFFEMSKETIIKCEKQKPRFHAFLKINQAKPECGRQSLVELLIRPVQRL
PSVALLLNDLKKHTADENPDKSTLEKAIGSLKEVMTHINEDKRKTEAQKQIFDVVYEVDG
CPANLLSSHRSLVQRVETISLGEHPCDRGEQVTLFLFNDCLEIARKRHKVIGTFRSPHGQ
TRPPASLKHIHLMPLSQIKKVLDIRETEDCHNAFALLVRPPTEQANVLLSFQMTSDELPK
ENWLKMLCRHVANTICKADAENLIYTADPESFEVNTKDMDSTLSRASRAIKKTSKKVTRA
FSFSKTPKRALRRALMTSHGSVEGRSPSSNDKHVMSRLSSTSSLAGIPSPSLVSLPSFFE
RRSHTLSRSTTHLI
Target Bioclass
Other
Subcellular location
Early endosome membrane
Function May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis.
Uniprot ID
Q9H8W4
Ensemble ID
ENST00000315367.4
HGNC ID
HGNC:20757

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 10 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		13.86  LDD0402  [1]
DBIA
 Probe Info  		C183(1.15); C186(1.15); C178(1.02)  LDD0078  [2]
ATP probe
 Probe Info  		K44(0.00); K107(0.00); K76(0.00)  LDD0199  [3]
4-Iodoacetamidophenylacetylene
 Probe Info  		C129(0.00); C21(0.00); C158(0.00)  LDD0038  [4]
IA-alkyne
 Probe Info  		C129(0.00); C158(0.00); C21(0.00)  LDD0036  [4]
Lodoacetamide azide
 Probe Info  		C129(0.00); C21(0.00); C158(0.00)  LDD0037  [4]
JW-RF-010
 Probe Info  		N.A.  LDD0026  [5]
IPM
 Probe Info  		N.A.  LDD2156  [6]
TFBX
 Probe Info  		N.A.  LDD0148  [5]
NAIA_5
 Probe Info  		C21(0.00); C129(0.00)  LDD2223  [7]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0026  4SU-RNA+native RNA HEK-293T C158(2.67)  LDD0372  [8]
 LDCM0214  AC1 HCT 116 C178(0.91); C183(0.88); C186(0.88); C207(1.04)  LDD0531  [2]
 LDCM0215  AC10 HCT 116 C178(1.04); C183(1.10); C186(1.13); C204(1.35)  LDD0532  [2]
 LDCM0216  AC100 HCT 116 C158(0.84); C178(0.96); C183(1.06); C186(1.02)  LDD0533  [2]
 LDCM0217  AC101 HCT 116 C158(0.83); C178(0.92); C183(0.95); C186(0.92)  LDD0534  [2]
 LDCM0218  AC102 HCT 116 C158(0.96); C178(0.90); C183(0.93); C186(0.91)  LDD0535  [2]
 LDCM0219  AC103 HCT 116 C158(1.03); C178(1.04); C183(1.23); C186(1.16)  LDD0536  [2]
 LDCM0220  AC104 HCT 116 C158(0.86); C178(0.92); C183(1.01); C186(0.96)  LDD0537  [2]
 LDCM0221  AC105 HCT 116 C158(0.92); C178(0.99); C183(1.09); C186(1.06)  LDD0538  [2]
 LDCM0222  AC106 HCT 116 C158(0.96); C178(1.08); C183(1.20); C186(1.17)  LDD0539  [2]
 LDCM0223  AC107 HCT 116 C158(0.75); C178(0.89); C183(1.12); C186(1.10)  LDD0540  [2]
 LDCM0224  AC108 HCT 116 C158(0.99); C178(0.93); C183(0.95); C186(0.96)  LDD0541  [2]
 LDCM0225  AC109 HCT 116 C158(0.96); C178(0.74); C183(0.81); C186(0.80)  LDD0542  [2]
 LDCM0226  AC11 HCT 116 C178(1.07); C183(1.12); C186(1.14); C204(1.35)  LDD0543  [2]
 LDCM0227  AC110 HCT 116 C158(1.03); C178(0.81); C183(0.87); C186(0.88)  LDD0544  [2]
 LDCM0228  AC111 HCT 116 C158(1.02); C178(0.91); C183(0.92); C186(0.89)  LDD0545  [2]
 LDCM0229  AC112 HCT 116 C158(0.83); C178(0.89); C183(1.05); C186(1.03)  LDD0546  [2]
 LDCM0230  AC113 HCT 116 C158(0.99); C178(0.95); C183(0.92); C186(0.94)  LDD0547  [2]
 LDCM0231  AC114 HCT 116 C158(1.07); C178(1.06); C183(1.08); C186(1.05)  LDD0548  [2]
 LDCM0232  AC115 HCT 116 C158(0.99); C178(1.02); C183(1.17); C186(1.14)  LDD0549  [2]
 LDCM0233  AC116 HCT 116 C158(0.78); C178(1.45); C183(1.08); C186(1.25)  LDD0550  [2]
 LDCM0234  AC117 HCT 116 C158(0.96); C178(1.16); C183(0.99); C186(1.05)  LDD0551  [2]
 LDCM0235  AC118 HCT 116 C158(1.08); C178(1.05); C183(0.94); C186(0.99)  LDD0552  [2]
 LDCM0236  AC119 HCT 116 C158(0.88); C178(1.19); C183(1.21); C186(1.24)  LDD0553  [2]
 LDCM0237  AC12 HCT 116 C178(1.09); C183(1.00); C186(1.04); C204(1.12)  LDD0554  [2]
 LDCM0238  AC120 HCT 116 C158(1.03); C178(0.81); C183(0.94); C186(0.91)  LDD0555  [2]
 LDCM0239  AC121 HCT 116 C158(0.90); C178(1.01); C183(1.06); C186(1.01)  LDD0556  [2]
 LDCM0240  AC122 HCT 116 C158(0.91); C178(1.23); C183(1.21); C186(1.22)  LDD0557  [2]
 LDCM0241  AC123 HCT 116 C158(0.89); C178(0.97); C183(0.94); C186(0.96)  LDD0558  [2]
 LDCM0242  AC124 HCT 116 C158(0.80); C178(1.11); C183(0.98); C186(1.03)  LDD0559  [2]
 LDCM0243  AC125 HCT 116 C158(1.09); C178(1.20); C183(1.21); C186(1.20)  LDD0560  [2]
 LDCM0244  AC126 HCT 116 C158(0.94); C178(1.39); C183(1.19); C186(1.25)  LDD0561  [2]
 LDCM0245  AC127 HCT 116 C158(0.76); C178(1.34); C183(1.17); C186(1.24)  LDD0562  [2]
 LDCM0246  AC128 HCT 116 C178(0.83); C183(0.85); C186(1.01); C21(0.69)  LDD0563  [2]
 LDCM0247  AC129 HCT 116 C178(0.64); C183(0.74); C186(0.83); C21(1.31)  LDD0564  [2]
 LDCM0249  AC130 HCT 116 C178(0.92); C183(0.85); C186(1.08); C21(1.13)  LDD0566  [2]
 LDCM0250  AC131 HCT 116 C178(0.97); C183(0.70); C186(1.00); C21(0.99)  LDD0567  [2]
 LDCM0251  AC132 HCT 116 C178(0.67); C183(0.69); C186(0.80); C21(0.80)  LDD0568  [2]
 LDCM0252  AC133 HCT 116 C178(0.62); C183(0.87); C186(0.88); C21(1.21)  LDD0569  [2]
 LDCM0253  AC134 HCT 116 C178(0.67); C183(0.78); C186(0.84); C21(1.30)  LDD0570  [2]
 LDCM0254  AC135 HCT 116 C178(1.00); C183(0.84); C186(1.11); C21(1.15)  LDD0571  [2]
 LDCM0255  AC136 HCT 116 C178(0.56); C183(0.73); C186(0.73); C21(0.86)  LDD0572  [2]
 LDCM0256  AC137 HCT 116 C178(0.55); C183(0.67); C186(0.69); C21(0.86)  LDD0573  [2]
 LDCM0257  AC138 HCT 116 C178(0.68); C183(0.85); C186(0.89); C21(1.28)  LDD0574  [2]
 LDCM0258  AC139 HCT 116 C178(0.92); C183(0.82); C186(1.01); C21(0.94)  LDD0575  [2]
 LDCM0259  AC14 HCT 116 C178(1.04); C183(1.06); C186(1.09); C204(1.24)  LDD0576  [2]
 LDCM0260  AC140 HCT 116 C178(0.86); C183(0.87); C186(1.02); C21(0.94)  LDD0577  [2]
 LDCM0261  AC141 HCT 116 C178(0.93); C183(0.87); C186(1.06); C21(1.37)  LDD0578  [2]
 LDCM0262  AC142 HCT 116 C178(0.76); C183(0.80); C186(0.91); C21(0.86)  LDD0579  [2]
 LDCM0263  AC143 HCT 116 C178(0.89); C186(1.05); C183(1.05); C204(1.10)  LDD0580  [2]
 LDCM0264  AC144 HCT 116 C178(1.26); C204(1.58); C219(1.58); C183(1.72)  LDD0581  [2]
 LDCM0265  AC145 HCT 116 C178(1.04); C186(1.15); C183(1.16); C204(1.36)  LDD0582  [2]
 LDCM0266  AC146 HCT 116 C178(0.99); C183(1.22); C186(1.23); C204(1.93)  LDD0583  [2]
 LDCM0267  AC147 HCT 116 C204(0.97); C219(0.97); C178(1.09); C183(1.49)  LDD0584  [2]
 LDCM0268  AC148 HCT 116 C178(1.30); C186(1.59); C183(1.70); C204(1.71)  LDD0585  [2]
 LDCM0269  AC149 HCT 116 C178(1.19); C183(1.41); C186(1.44); C204(1.85)  LDD0586  [2]
 LDCM0270  AC15 HCT 116 C21(0.96); C207(1.04); C178(1.05); C183(1.09)  LDD0587  [2]
 LDCM0271  AC150 HCT 116 C178(1.01); C204(1.22); C219(1.22); C186(1.32)  LDD0588  [2]
 LDCM0272  AC151 HCT 116 C204(1.05); C219(1.05); C178(1.07); C186(1.23)  LDD0589  [2]
 LDCM0273  AC152 HCT 116 C178(1.21); C183(1.27); C186(1.27); C204(1.62)  LDD0590  [2]
 LDCM0274  AC153 HCT 116 C178(1.33); C204(1.62); C219(1.62); C186(1.85)  LDD0591  [2]
 LDCM0621  AC154 HCT 116 C178(1.17); C183(1.40); C186(1.40); C204(1.55)  LDD2158  [2]
 LDCM0622  AC155 HCT 116 C178(1.17); C183(1.35); C186(1.35); C204(1.57)  LDD2159  [2]
 LDCM0623  AC156 HCT 116 C178(1.00); C183(1.20); C186(1.22); C204(1.41)  LDD2160  [2]
 LDCM0624  AC157 HCT 116 C178(0.98); C183(1.19); C186(1.17); C204(1.48)  LDD2161  [2]
 LDCM0276  AC17 HCT 116 C178(0.79); C183(0.82); C186(0.82); C21(1.09)  LDD0593  [2]
 LDCM0277  AC18 HCT 116 C178(0.85); C183(0.85); C186(0.85); C21(0.99)  LDD0594  [2]
 LDCM0278  AC19 HCT 116 C178(0.87); C183(0.88); C186(0.88); C21(1.43)  LDD0595  [2]
 LDCM0279  AC2 HCT 116 C21(0.93); C183(1.00); C186(1.00); C207(1.06)  LDD0596  [2]
 LDCM0280  AC20 HCT 116 C178(0.73); C183(0.76); C186(0.76); C21(1.08)  LDD0597  [2]
 LDCM0281  AC21 HCT 116 C178(0.88); C183(0.92); C186(0.92); C21(1.03)  LDD0598  [2]
 LDCM0282  AC22 HCT 116 C178(0.72); C183(0.82); C186(0.82); C21(1.50)  LDD0599  [2]
 LDCM0283  AC23 HCT 116 C178(0.73); C183(0.75); C186(0.75); C21(0.96)  LDD0600  [2]
 LDCM0284  AC24 HCT 116 C178(0.75); C183(0.78); C186(0.78); C21(1.01)  LDD0601  [2]
 LDCM0285  AC25 HCT 116 C21(0.90); C178(1.28); C186(1.30); C183(1.66)  LDD0602  [2]
 LDCM0286  AC26 HCT 116 C21(0.83); C178(1.34); C186(1.41); C183(1.79)  LDD0603  [2]
 LDCM0287  AC27 HCT 116 C21(0.83); C178(1.50); C186(1.51); C183(1.95)  LDD0604  [2]
 LDCM0288  AC28 HCT 116 C21(0.84); C178(1.47); C186(1.56); C183(2.19)  LDD0605  [2]
 LDCM0289  AC29 HCT 116 C21(0.97); C186(1.42); C178(1.50); C183(1.98)  LDD0606  [2]
 LDCM0290  AC3 HCT 116 C178(0.83); C207(0.85); C219(0.85); C183(0.93)  LDD0607  [2]
 LDCM0291  AC30 HCT 116 C21(0.94); C186(1.58); C178(1.61); C183(2.11)  LDD0608  [2]
 LDCM0292  AC31 HCT 116 C21(0.92); C186(1.35); C178(1.45); C183(1.57)  LDD0609  [2]
 LDCM0293  AC32 HCT 116 C21(0.84); C186(1.47); C178(1.49); C183(1.71)  LDD0610  [2]
 LDCM0294  AC33 HCT 116 C21(0.93); C186(1.70); C178(1.70); C183(2.41)  LDD0611  [2]
 LDCM0295  AC34 HCT 116 C21(0.78); C178(1.54); C186(1.65); C183(2.32)  LDD0612  [2]
 LDCM0296  AC35 HCT 116 C158(0.89); C186(0.90); C183(0.92); C178(0.94)  LDD0613  [2]
 LDCM0297  AC36 HCT 116 C186(1.01); C183(1.04); C178(1.05); C21(1.08)  LDD0614  [2]
 LDCM0298  AC37 HCT 116 C158(0.84); C129(1.08); C21(1.09); C186(1.15)  LDD0615  [2]
 LDCM0299  AC38 HCT 116 C158(0.83); C21(0.96); C186(1.03); C183(1.03)  LDD0616  [2]
 LDCM0300  AC39 HCT 116 C21(1.06); C183(1.13); C186(1.17); C178(1.22)  LDD0617  [2]
 LDCM0301  AC4 HCT 116 C178(0.80); C207(0.83); C219(0.83); C183(0.89)  LDD0618  [2]
 LDCM0302  AC40 HCT 116 C21(1.02); C158(1.16); C183(1.16); C186(1.23)  LDD0619  [2]
 LDCM0303  AC41 HCT 116 C158(0.91); C183(1.01); C186(1.02); C21(1.03)  LDD0620  [2]
 LDCM0304  AC42 HCT 116 C158(0.73); C183(1.03); C186(1.04); C178(1.06)  LDD0621  [2]
 LDCM0305  AC43 HCT 116 C158(0.83); C183(1.13); C186(1.16); C129(1.17)  LDD0622  [2]
 LDCM0306  AC44 HCT 116 C158(0.85); C21(1.08); C183(1.14); C186(1.15)  LDD0623  [2]
 LDCM0307  AC45 HCT 116 C158(0.82); C21(0.91); C129(1.10); C183(1.21)  LDD0624  [2]
 LDCM0308  AC46 HCT 116 C129(0.86); C183(0.96); C186(0.96); C178(0.98)  LDD0625  [2]
 LDCM0309  AC47 HCT 116 C21(0.88); C129(0.91); C183(0.94); C186(0.94)  LDD0626  [2]
 LDCM0310  AC48 HCT 116 C183(0.97); C186(0.97); C21(0.98); C129(0.98)  LDD0627  [2]
 LDCM0311  AC49 HCT 116 C129(0.80); C21(0.87); C183(1.11); C186(1.11)  LDD0628  [2]
 LDCM0312  AC5 HCT 116 C178(0.85); C207(0.88); C219(0.88); C183(0.90)  LDD0629  [2]
 LDCM0313  AC50 HCT 116 C129(0.83); C21(0.87); C178(1.03); C183(1.09)  LDD0630  [2]
 LDCM0314  AC51 HCT 116 C183(0.86); C186(0.86); C178(0.90); C129(0.92)  LDD0631  [2]
 LDCM0315  AC52 HCT 116 C21(0.94); C183(0.99); C186(0.99); C129(1.04)  LDD0632  [2]
 LDCM0316  AC53 HCT 116 C21(0.86); C129(0.88); C183(1.01); C186(1.01)  LDD0633  [2]
 LDCM0317  AC54 HCT 116 C129(0.83); C21(1.01); C183(1.18); C186(1.18)  LDD0634  [2]
 LDCM0318  AC55 HCT 116 C129(0.76); C21(0.98); C183(1.11); C186(1.11)  LDD0635  [2]
 LDCM0319  AC56 HCT 116 C129(0.74); C219(0.78); C21(1.02); C183(1.25)  LDD0636  [2]
 LDCM0320  AC57 HCT 116 C158(0.69); C21(0.99); C178(1.07); C186(1.12)  LDD0637  [2]
 LDCM0321  AC58 HCT 116 C183(1.00); C186(1.10); C158(1.15); C178(1.19)  LDD0638  [2]
 LDCM0322  AC59 HCT 116 C178(0.99); C186(1.07); C183(1.09); C158(1.27)  LDD0639  [2]
 LDCM0323  AC6 HCT 116 C21(0.84); C207(0.85); C219(0.87); C204(0.90)  LDD0640  [2]
 LDCM0324  AC60 HCT 116 C204(0.82); C219(0.82); C21(1.00); C158(1.05)  LDD0641  [2]
 LDCM0325  AC61 HCT 116 C178(0.94); C204(0.95); C219(0.95); C158(0.97)  LDD0642  [2]
 LDCM0326  AC62 HCT 116 C158(1.00); C178(1.12); C186(1.20); C183(1.24)  LDD0643  [2]
 LDCM0327  AC63 HCT 116 C183(1.08); C158(1.09); C178(1.11); C186(1.13)  LDD0644  [2]
 LDCM0328  AC64 HCT 116 C158(1.04); C204(1.07); C219(1.07); C178(1.15)  LDD0645  [2]
 LDCM0329  AC65 HCT 116 C204(0.75); C219(0.75); C186(0.84); C183(0.84)  LDD0646  [2]
 LDCM0330  AC66 HCT 116 C183(0.74); C186(0.76); C178(0.77); C158(0.90)  LDD0647  [2]
 LDCM0331  AC67 HCT 116 C204(0.79); C219(0.79); C183(0.82); C186(0.84)  LDD0648  [2]
 LDCM0332  AC68 HCT 116 C21(0.98); C204(1.00); C219(1.00); C183(1.75)  LDD0649  [2]
 LDCM0333  AC69 HCT 116 C21(1.03); C204(1.18); C219(1.18); C178(1.89)  LDD0650  [2]
 LDCM0334  AC7 HCT 116 C207(0.53); C219(0.67); C204(0.81); C178(0.90)  LDD0651  [2]
 LDCM0335  AC70 HCT 116 C204(1.01); C219(1.01); C21(1.07); C178(1.76)  LDD0652  [2]
 LDCM0336  AC71 HCT 116 C204(0.87); C219(0.87); C21(1.05); C183(1.62)  LDD0653  [2]
 LDCM0337  AC72 HCT 116 C21(1.09); C204(1.43); C219(1.43); C183(1.56)  LDD0654  [2]
 LDCM0338  AC73 HCT 116 C21(0.99); C204(1.31); C219(1.31); C178(1.86)  LDD0655  [2]
 LDCM0339  AC74 HCT 116 C21(1.15); C204(1.27); C219(1.27); C178(1.52)  LDD0656  [2]
 LDCM0340  AC75 HCT 116 C21(1.04); C204(1.27); C219(1.27); C178(1.79)  LDD0657  [2]
 LDCM0341  AC76 HCT 116 C21(1.02); C204(1.29); C219(1.29); C178(1.61)  LDD0658  [2]
 LDCM0342  AC77 HCT 116 C21(0.98); C204(1.24); C219(1.24); C178(1.87)  LDD0659  [2]
 LDCM0343  AC78 HCT 116 C21(1.03); C183(1.40); C186(1.40); C204(1.42)  LDD0660  [2]
 LDCM0344  AC79 HCT 116 C204(0.99); C219(0.99); C21(1.13); C183(1.60)  LDD0661  [2]
 LDCM0345  AC8 HCT 116 C207(0.57); C219(0.71); C21(0.84); C204(0.85)  LDD0662  [2]
 LDCM0346  AC80 HCT 116 C21(1.11); C204(1.41); C219(1.41); C178(1.82)  LDD0663  [2]
 LDCM0347  AC81 HCT 116 C204(0.81); C219(0.81); C21(1.21); C183(1.60)  LDD0664  [2]
 LDCM0348  AC82 HCT 116 C21(1.31); C204(1.60); C219(1.60); C183(1.70)  LDD0665  [2]
 LDCM0349  AC83 HCT 116 C158(1.12); C183(1.16); C178(1.38); C186(1.47)  LDD0666  [2]
 LDCM0350  AC84 HCT 116 C158(1.03); C183(1.20); C178(1.21); C186(1.32)  LDD0667  [2]
 LDCM0351  AC85 HCT 116 C178(0.98); C158(1.05); C186(1.09); C183(1.25)  LDD0668  [2]
 LDCM0352  AC86 HCT 116 C158(1.05); C178(1.06); C186(1.10); C183(1.12)  LDD0669  [2]
 LDCM0353  AC87 HCT 116 C158(1.02); C183(1.06); C178(1.09); C186(1.15)  LDD0670  [2]
 LDCM0354  AC88 HCT 116 C158(0.81); C178(0.97); C183(1.02); C186(1.03)  LDD0671  [2]
 LDCM0355  AC89 HCT 116 C158(1.06); C183(1.14); C178(1.24); C186(1.31)  LDD0672  [2]
 LDCM0357  AC90 HCT 116 C158(0.84); C178(0.86); C186(0.92); C183(1.20)  LDD0674  [2]
 LDCM0358  AC91 HCT 116 C183(1.08); C158(1.19); C178(1.27); C186(1.30)  LDD0675  [2]
 LDCM0359  AC92 HCT 116 C158(0.98); C183(1.08); C178(1.09); C186(1.18)  LDD0676  [2]
 LDCM0360  AC93 HCT 116 C178(0.85); C158(0.87); C186(0.94); C183(1.06)  LDD0677  [2]
 LDCM0361  AC94 HCT 116 C178(0.94); C186(0.99); C183(1.11); C158(1.12)  LDD0678  [2]
 LDCM0362  AC95 HCT 116 C158(0.82); C178(1.04); C186(1.10); C183(1.10)  LDD0679  [2]
 LDCM0363  AC96 HCT 116 C183(1.02); C158(1.03); C178(1.17); C186(1.21)  LDD0680  [2]
 LDCM0364  AC97 HCT 116 C178(1.14); C186(1.17); C183(1.27); C158(1.34)  LDD0681  [2]
 LDCM0365  AC98 HCT 116 C178(1.02); C158(1.07); C186(1.37); C183(1.53)  LDD0682  [2]
 LDCM0366  AC99 HCT 116 C204(0.67); C219(0.67); C158(0.79); C186(0.86)  LDD0683  [2]
 LDCM0248  AKOS034007472 HCT 116 C178(0.98); C183(1.05); C186(1.03); C204(1.10)  LDD0565  [2]
 LDCM0356  AKOS034007680 HCT 116 C207(0.51); C219(0.76); C204(1.01); C183(1.04)  LDD0673  [2]
 LDCM0275  AKOS034007705 HCT 116 C21(0.92); C207(1.20); C219(1.25); C204(1.30)  LDD0592  [2]
 LDCM0156  Aniline NCI-H1299 8.95  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C183(1.15); C186(1.15); C178(1.02)  LDD0078  [2]
 LDCM0632  CL-Sc Hep-G2 C21(20.00)  LDD2227  [7]
 LDCM0367  CL1 HCT 116 C207(0.75); C219(0.77); C183(0.83); C204(0.84)  LDD0684  [2]
 LDCM0368  CL10 HCT 116 C183(0.99); C21(0.99); C186(1.00); C178(1.03)  LDD0685  [2]
 LDCM0369  CL100 HCT 116 C178(0.89); C183(0.91); C186(0.91); C21(0.96)  LDD0686  [2]
 LDCM0370  CL101 HCT 116 C207(0.68); C219(0.91); C21(0.95); C186(1.06)  LDD0687  [2]
 LDCM0371  CL102 HCT 116 C207(0.81); C183(0.90); C186(0.93); C178(0.95)  LDD0688  [2]
 LDCM0372  CL103 HCT 116 C207(0.68); C219(0.77); C204(0.86); C183(0.94)  LDD0689  [2]
 LDCM0373  CL104 HCT 116 C207(0.73); C21(0.97); C219(0.99); C178(1.01)  LDD0690  [2]
 LDCM0374  CL105 HCT 116 C178(0.89); C183(0.93); C186(0.93); C21(1.54)  LDD0691  [2]
 LDCM0375  CL106 HCT 116 C178(0.83); C183(0.89); C186(0.89); C21(1.06)  LDD0692  [2]
 LDCM0376  CL107 HCT 116 C178(0.82); C183(0.93); C186(0.93); C21(1.36)  LDD0693  [2]
 LDCM0377  CL108 HCT 116 C178(0.82); C183(0.90); C186(0.90); C21(1.18)  LDD0694  [2]
 LDCM0378  CL109 HCT 116 C178(0.86); C183(0.92); C186(0.92); C21(1.17)  LDD0695  [2]
 LDCM0379  CL11 HCT 116 C183(1.08); C207(1.09); C186(1.09); C178(1.10)  LDD0696  [2]
 LDCM0380  CL110 HCT 116 C178(0.88); C183(0.91); C186(0.91); C21(1.10)  LDD0697  [2]
 LDCM0381  CL111 HCT 116 C178(0.84); C183(0.86); C186(0.86); C21(1.08)  LDD0698  [2]
 LDCM0382  CL112 HCT 116 C21(0.75); C178(1.07); C186(1.08); C183(1.27)  LDD0699  [2]
 LDCM0383  CL113 HCT 116 C21(0.80); C178(1.30); C186(1.35); C183(1.71)  LDD0700  [2]
 LDCM0384  CL114 HCT 116 C21(0.82); C178(1.24); C186(1.30); C183(1.78)  LDD0701  [2]
 LDCM0385  CL115 HCT 116 C21(0.81); C186(1.61); C178(1.84); C183(2.19)  LDD0702  [2]
 LDCM0386  CL116 HCT 116 C21(0.98); C186(1.54); C178(1.60); C183(2.14)  LDD0703  [2]
 LDCM0387  CL117 HCT 116 C158(0.88); C21(0.93); C129(1.28); C183(1.33)  LDD0704  [2]
 LDCM0388  CL118 HCT 116 C158(0.70); C21(1.06); C183(1.06); C186(1.13)  LDD0705  [2]
 LDCM0389  CL119 HCT 116 C158(0.91); C186(1.06); C21(1.09); C178(1.10)  LDD0706  [2]
 LDCM0390  CL12 HCT 116 C219(1.06); C207(1.06); C204(1.12); C183(1.15)  LDD0707  [2]
 LDCM0391  CL120 HCT 116 C158(0.85); C183(1.15); C129(1.15); C21(1.17)  LDD0708  [2]
 LDCM0392  CL121 HCT 116 C129(0.92); C219(1.03); C21(1.48); C183(2.76)  LDD0709  [2]
 LDCM0393  CL122 HCT 116 C21(0.91); C129(0.94); C219(0.95); C183(0.97)  LDD0710  [2]
 LDCM0394  CL123 HCT 116 C219(0.80); C129(0.86); C21(0.89); C183(0.95)  LDD0711  [2]
 LDCM0395  CL124 HCT 116 C219(0.73); C21(0.84); C129(0.85); C183(1.04)  LDD0712  [2]
 LDCM0396  CL125 HCT 116 C183(0.95); C186(0.95); C178(0.96); C158(0.97)  LDD0713  [2]
 LDCM0397  CL126 HCT 116 C158(0.90); C183(0.94); C186(1.01); C21(1.03)  LDD0714  [2]
 LDCM0398  CL127 HCT 116 C204(0.70); C219(0.70); C178(0.94); C183(0.95)  LDD0715  [2]
 LDCM0399  CL128 HCT 116 C158(0.80); C183(1.17); C186(1.18); C178(1.21)  LDD0716  [2]
 LDCM0400  CL13 HCT 116 C207(0.98); C219(1.00); C21(1.04); C204(1.07)  LDD0717  [2]
 LDCM0401  CL14 HCT 116 C207(0.82); C219(0.84); C204(0.90); C186(1.02)  LDD0718  [2]
 LDCM0402  CL15 HCT 116 C21(1.02); C219(1.02); C207(1.05); C186(1.08)  LDD0719  [2]
 LDCM0403  CL16 HCT 116 C21(0.94); C186(1.17); C183(1.17); C204(1.24)  LDD0720  [2]
 LDCM0404  CL17 HCT 116 C21(0.88); C158(0.93); C183(0.99); C186(1.00)  LDD0721  [2]
 LDCM0405  CL18 HCT 116 C158(0.90); C21(0.99); C186(1.14); C183(1.16)  LDD0722  [2]
 LDCM0406  CL19 HCT 116 C158(0.97); C183(1.11); C186(1.12); C21(1.12)  LDD0723  [2]
 LDCM0407  CL2 HCT 116 C207(0.75); C219(0.77); C204(0.89); C183(0.92)  LDD0724  [2]
 LDCM0408  CL20 HCT 116 C21(1.09); C158(1.20); C186(1.28); C183(1.29)  LDD0725  [2]
 LDCM0409  CL21 HCT 116 C158(0.86); C21(1.04); C183(1.28); C186(1.29)  LDD0726  [2]
 LDCM0410  CL22 HCT 116 C21(0.97); C158(1.20); C178(1.41); C183(1.42)  LDD0727  [2]
 LDCM0411  CL23 HCT 116 C21(1.09); C186(1.24); C183(1.26); C178(1.34)  LDD0728  [2]
 LDCM0412  CL24 HCT 116 C158(0.95); C21(1.01); C186(1.46); C183(1.47)  LDD0729  [2]
 LDCM0413  CL25 HCT 116 C158(0.80); C178(1.40); C183(1.32); C186(1.31)  LDD0730  [2]
 LDCM0414  CL26 HCT 116 C158(0.96); C178(1.43); C183(1.28); C186(1.29)  LDD0731  [2]
 LDCM0415  CL27 HCT 116 C158(1.06); C178(1.39); C183(1.31); C186(1.31)  LDD0732  [2]
 LDCM0416  CL28 HCT 116 C158(0.82); C178(1.71); C183(1.52); C186(1.51)  LDD0733  [2]
 LDCM0417  CL29 HCT 116 C158(1.15); C178(1.47); C183(1.38); C186(1.36)  LDD0734  [2]
 LDCM0418  CL3 HCT 116 C178(1.03); C183(0.96); C186(0.99); C204(0.99)  LDD0735  [2]
 LDCM0419  CL30 HCT 116 C158(0.82); C178(1.45); C183(1.34); C186(1.33)  LDD0736  [2]
 LDCM0420  CL31 HCT 116 C129(1.13); C158(0.86); C178(0.91); C183(1.00)  LDD0737  [2]
 LDCM0421  CL32 HCT 116 C129(0.78); C178(0.87); C183(0.98); C186(0.94)  LDD0738  [2]
 LDCM0422  CL33 HCT 116 C129(1.04); C178(0.76); C183(0.81); C186(0.82)  LDD0739  [2]
 LDCM0423  CL34 HCT 116 C129(1.82); C178(0.89); C183(0.98); C186(0.98)  LDD0740  [2]
 LDCM0424  CL35 HCT 116 C129(1.75); C178(1.06); C183(1.11); C186(1.11)  LDD0741  [2]
 LDCM0425  CL36 HCT 116 C129(1.28); C178(0.93); C183(0.94); C186(0.99)  LDD0742  [2]
 LDCM0426  CL37 HCT 116 C129(1.36); C178(1.11); C183(1.10); C186(1.17)  LDD0743  [2]
 LDCM0428  CL39 HCT 116 C129(1.38); C178(0.94); C183(1.03); C186(1.06)  LDD0745  [2]
 LDCM0429  CL4 HCT 116 C178(1.05); C183(1.06); C186(1.03); C204(0.98)  LDD0746  [2]
 LDCM0430  CL40 HCT 116 C129(1.27); C178(1.11); C183(1.16); C186(1.17)  LDD0747  [2]
 LDCM0431  CL41 HCT 116 C129(1.30); C178(0.98); C183(1.04); C186(1.06)  LDD0748  [2]
 LDCM0432  CL42 HCT 116 C129(1.25); C178(1.09); C183(1.12); C186(1.19)  LDD0749  [2]
 LDCM0433  CL43 HCT 116 C129(1.47); C178(1.02); C183(1.09); C186(1.13)  LDD0750  [2]
 LDCM0434  CL44 HCT 116 C129(1.23); C178(1.06); C183(1.09); C186(1.14)  LDD0751  [2]
 LDCM0435  CL45 HCT 116 C129(1.47); C178(1.04); C183(1.13); C186(1.14)  LDD0752  [2]
 LDCM0436  CL46 HCT 116 C178(0.92); C183(0.87); C186(0.94); C207(1.16)  LDD0753  [2]
 LDCM0437  CL47 HCT 116 C178(0.95); C183(0.93); C186(0.97); C207(1.09)  LDD0754  [2]
 LDCM0438  CL48 HCT 116 C178(0.99); C183(0.99); C186(1.03); C207(1.50)  LDD0755  [2]
 LDCM0439  CL49 HCT 116 C178(0.93); C183(0.91); C186(0.96); C207(1.32)  LDD0756  [2]
 LDCM0440  CL5 HCT 116 C178(0.99); C183(0.95); C186(0.97); C204(0.97)  LDD0757  [2]
 LDCM0441  CL50 HCT 116 C178(0.87); C183(0.88); C186(0.90); C207(0.56)  LDD0758  [2]
 LDCM0442  CL51 HCT 116 C178(1.00); C183(1.02); C186(1.03); C207(0.94)  LDD0759  [2]
 LDCM0443  CL52 HCT 116 C178(1.13); C183(1.12); C186(1.12); C207(0.91)  LDD0760  [2]
 LDCM0444  CL53 HCT 116 C178(0.85); C183(0.93); C186(0.89); C207(1.07)  LDD0761  [2]
 LDCM0445  CL54 HCT 116 C178(1.02); C183(1.01); C186(1.02); C207(0.89)  LDD0762  [2]
 LDCM0446  CL55 HCT 116 C178(0.91); C183(0.94); C186(0.94); C207(0.93)  LDD0763  [2]
 LDCM0447  CL56 HCT 116 C178(1.01); C183(1.00); C186(1.04); C207(1.30)  LDD0764  [2]
 LDCM0448  CL57 HCT 116 C178(1.00); C183(1.01); C186(1.03); C207(1.22)  LDD0765  [2]
 LDCM0449  CL58 HCT 116 C178(0.93); C183(0.93); C186(0.94); C207(3.17)  LDD0766  [2]
 LDCM0450  CL59 HCT 116 C178(0.95); C183(0.92); C186(0.95); C207(1.77)  LDD0767  [2]
 LDCM0451  CL6 HCT 116 C178(0.98); C183(0.90); C186(0.96); C204(0.98)  LDD0768  [2]
 LDCM0452  CL60 HCT 116 C178(0.94); C183(0.94); C186(0.95); C207(1.03)  LDD0769  [2]
 LDCM0453  CL61 HCT 116 C129(0.78); C178(0.84); C183(0.95); C186(0.96)  LDD0770  [2]
 LDCM0454  CL62 HCT 116 C129(0.96); C178(0.79); C183(0.90); C186(0.86)  LDD0771  [2]
 LDCM0455  CL63 HCT 116 C129(0.96); C178(0.86); C183(0.99); C186(0.93)  LDD0772  [2]
 LDCM0456  CL64 HCT 116 C129(0.93); C178(0.95); C183(1.07); C186(1.03)  LDD0773  [2]
 LDCM0457  CL65 HCT 116 C129(0.93); C178(0.83); C183(0.88); C186(0.85)  LDD0774  [2]
 LDCM0458  CL66 HCT 116 C129(0.94); C178(1.02); C183(1.10); C186(1.03)  LDD0775  [2]
 LDCM0459  CL67 HCT 116 C129(0.85); C178(0.99); C183(1.07); C186(1.03)  LDD0776  [2]
 LDCM0460  CL68 HCT 116 C129(0.98); C178(0.89); C183(1.05); C186(0.99)  LDD0777  [2]
 LDCM0461  CL69 HCT 116 C129(0.78); C178(0.89); C183(0.99); C186(0.96)  LDD0778  [2]
 LDCM0462  CL7 HCT 116 C178(1.15); C183(1.12); C186(1.12); C204(1.15)  LDD0779  [2]
 LDCM0463  CL70 HCT 116 C129(0.78); C178(1.01); C183(1.01); C186(1.05)  LDD0780  [2]
 LDCM0464  CL71 HCT 116 C129(0.85); C178(0.83); C183(1.03); C186(0.96)  LDD0781  [2]
 LDCM0465  CL72 HCT 116 C129(1.16); C178(1.03); C183(1.04); C186(1.03)  LDD0782  [2]
 LDCM0466  CL73 HCT 116 C129(0.76); C178(0.86); C183(0.97); C186(0.92)  LDD0783  [2]
 LDCM0467  CL74 HCT 116 C129(0.84); C178(0.92); C183(1.09); C186(1.03)  LDD0784  [2]
 LDCM0469  CL76 HCT 116 C178(1.08); C183(0.98); C186(1.17); C204(1.72)  LDD0786  [2]
 LDCM0470  CL77 HCT 116 C178(0.88); C183(0.84); C186(0.90); C204(1.21)  LDD0787  [2]
 LDCM0471  CL78 HCT 116 C178(1.10); C183(1.01); C186(1.09); C204(1.64)  LDD0788  [2]
 LDCM0472  CL79 HCT 116 C178(1.09); C183(1.10); C186(1.17); C204(1.36)  LDD0789  [2]
 LDCM0473  CL8 HCT 116 C178(1.03); C183(1.01); C186(1.04); C204(1.17)  LDD0790  [2]
 LDCM0474  CL80 HCT 116 C178(0.99); C183(1.01); C186(1.05); C204(1.12)  LDD0791  [2]
 LDCM0475  CL81 HCT 116 C178(0.99); C183(1.06); C186(1.14); C204(1.26)  LDD0792  [2]
 LDCM0476  CL82 HCT 116 C178(1.21); C183(1.02); C186(1.27); C204(1.64)  LDD0793  [2]
 LDCM0477  CL83 HCT 116 C178(1.09); C183(1.01); C186(1.12); C204(1.18)  LDD0794  [2]
 LDCM0478  CL84 HCT 116 C178(1.06); C183(1.03); C186(1.11); C204(1.80)  LDD0795  [2]
 LDCM0479  CL85 HCT 116 C178(0.93); C183(1.15); C186(1.12); C204(1.01)  LDD0796  [2]
 LDCM0480  CL86 HCT 116 C178(0.81); C183(1.02); C186(0.95); C204(0.86)  LDD0797  [2]
 LDCM0481  CL87 HCT 116 C178(0.96); C183(1.12); C186(1.15); C204(1.06)  LDD0798  [2]
 LDCM0482  CL88 HCT 116 C178(1.07); C183(1.21); C186(1.32); C204(1.52)  LDD0799  [2]
 LDCM0483  CL89 HCT 116 C178(1.15); C183(1.15); C186(1.27); C204(1.96)  LDD0800  [2]
 LDCM0484  CL9 HCT 116 C178(1.06); C183(0.97); C186(1.05); C204(0.96)  LDD0801  [2]
 LDCM0485  CL90 HCT 116 C178(0.76); C183(0.75); C186(0.81); C204(1.12)  LDD0802  [2]
 LDCM0486  CL91 HCT 116 C178(0.77); C183(1.03); C186(1.03); C207(1.00)  LDD0803  [2]
 LDCM0487  CL92 HCT 116 C178(0.87); C183(0.94); C186(0.94); C207(1.07)  LDD0804  [2]
 LDCM0488  CL93 HCT 116 C178(0.71); C183(0.91); C186(0.91); C207(0.94)  LDD0805  [2]
 LDCM0489  CL94 HCT 116 C178(0.94); C183(0.98); C186(0.98); C207(1.03)  LDD0806  [2]
 LDCM0490  CL95 HCT 116 C178(0.68); C183(0.91); C186(0.91); C207(0.88)  LDD0807  [2]
 LDCM0491  CL96 HCT 116 C178(0.91); C183(0.94); C186(0.94); C207(1.37)  LDD0808  [2]
 LDCM0492  CL97 HCT 116 C178(0.92); C183(0.84); C186(0.84); C207(1.11)  LDD0809  [2]
 LDCM0493  CL98 HCT 116 C178(0.96); C183(0.93); C186(0.93); C207(1.01)  LDD0810  [2]
 LDCM0494  CL99 HCT 116 C178(1.08); C183(0.90); C186(0.90); C207(1.09)  LDD0811  [2]
 LDCM0495  E2913 HEK-293T C158(0.86); C219(1.06)  LDD1698  [9]
 LDCM0625  F8 Ramos C129(0.85); C158(0.79)  LDD2187  [10]
 LDCM0572  Fragment10 Ramos C129(0.45); C158(0.78)  LDD2189  [10]
 LDCM0573  Fragment11 Ramos C129(0.30)  LDD2190  [10]
 LDCM0574  Fragment12 Ramos C129(0.69); C158(0.86)  LDD2191  [10]
 LDCM0575  Fragment13 Ramos C129(0.93); C158(0.96)  LDD2192  [10]
 LDCM0576  Fragment14 Ramos C129(0.67); C158(0.48)  LDD2193  [10]
 LDCM0579  Fragment20 Ramos C129(0.60); C158(0.91)  LDD2194  [10]
 LDCM0580  Fragment21 Ramos C129(0.99); C158(0.98)  LDD2195  [10]
 LDCM0582  Fragment23 Ramos C129(0.95); C158(1.34)  LDD2196  [10]
 LDCM0578  Fragment27 Ramos C129(0.94); C158(1.13)  LDD2197  [10]
 LDCM0586  Fragment28 Ramos C129(0.52); C158(0.60)  LDD2198  [10]
 LDCM0588  Fragment30 Ramos C129(1.10); C158(1.16)  LDD2199  [10]
 LDCM0589  Fragment31 Ramos C129(1.04); C158(1.09)  LDD2200  [10]
 LDCM0590  Fragment32 Ramos C129(0.33); C158(0.86)  LDD2201  [10]
 LDCM0468  Fragment33 HCT 116 C129(0.78); C178(0.97); C183(1.09); C186(1.05)  LDD0785  [2]
 LDCM0596  Fragment38 Ramos C129(0.96); C158(0.98)  LDD2203  [10]
 LDCM0566  Fragment4 Ramos C129(0.77); C158(0.52)  LDD2184  [10]
 LDCM0427  Fragment51 HCT 116 C129(1.41); C178(1.24); C183(1.33); C186(1.34)  LDD0744  [2]
 LDCM0610  Fragment52 Ramos C129(1.17); C158(1.33)  LDD2204  [10]
 LDCM0614  Fragment56 Ramos C129(1.20); C158(1.08)  LDD2205  [10]
 LDCM0569  Fragment7 Ramos C129(0.46); C158(0.59)  LDD2186  [10]
 LDCM0571  Fragment9 Ramos C129(0.49); C158(1.07)  LDD2188  [10]
 LDCM0022  KB02 HCT 116 C204(2.23); C207(2.75); C183(2.00); C186(2.00)  LDD0080  [2]
 LDCM0023  KB03 HCT 116 C204(1.85); C207(2.00); C183(1.57); C186(1.57)  LDD0081  [2]
 LDCM0024  KB05 HCT 116 C204(2.63); C207(2.45); C183(1.57); C186(1.57)  LDD0082  [2]
 LDCM0021  THZ1 HCT 116 C204(1.43); C207(1.43); C219(1.43); C178(1.29)  LDD2173  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 35 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
5'-3' exoribonuclease 2 (XRN2) 5'-3' exonuclease family Q9H0D6
5'-AMP-activated protein kinase subunit gamma-1 (PRKAG1) 5'-AMP-activated protein kinase gamma subunit family P54619
ATP-binding cassette sub-family G member 4 (ABCG4) ABCG family Q9H172
N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) (ACY3) AspA/AstE family Q96HD9
Histone-lysine N-methyltransferase NSD2 (NSD2) Histone-lysine methyltransferase family O96028
NADH dehydrogenase 1 alpha subcomplex subunit 5 (NDUFA5) Complex I NDUFA5 subunit family Q16718
Probable E3 ubiquitin-protein ligase DTX2 (DTX2) Deltex family Q86UW9
Probable palmitoyltransferase ZDHHC24 (ZDHHC24) DHHC palmitoyltransferase family Q6UX98
Thioredoxin-like protein 4B (TXNL4B) DIM1 family Q9NX01
Methylthioribose-1-phosphate isomerase (MRI1) EIF-2B alpha/beta/delta subunits family Q9BV20
Fumarylacetoacetase (FAH) FAH family P16930
Phosphopantothenoylcysteine decarboxylase (PPCDC) HFCD (homooligomeric flavin containing Cys decarboxylase) superfamily Q96CD2
Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] (NUDT2) Nudix hydrolase family P50583
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial (PDK4) PDK/BCKDK protein kinase family Q16654
AMSH-like protease (STAMBPL1) Peptidase M67C family Q96FJ0
Dual specificity mitogen-activated protein kinase kinase 1 (MAP2K1) STE Ser/Thr protein kinase family Q02750
Serine/threonine-protein kinase 3 (STK3) STE Ser/Thr protein kinase family Q13188
Dual specificity protein phosphatase 4 (DUSP4) Protein-tyrosine phosphatase family Q13115
Tyrosine-protein phosphatase non-receptor type 3 (PTPN3) Protein-tyrosine phosphatase family P26045
Ribulose-phosphate 3-epimerase (RPE) Ribulose-phosphate 3-epimerase family Q96AT9
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 (RPAP2) RPAP2 family Q8IXW5
Ras-related protein Rab-28 (RAB28) Rab family P51157
GTP-binding protein GEM (GEM) RGK family P55040
Chromatin-remodeling ATPase INO80 (INO80) SNF2/RAD54 helicase family Q9ULG1
TNF receptor-associated factor 6 (TRAF6) TNF receptor-associated factor family Q9Y4K3
GTP-binding protein 2 (GTPBP2) Classic translation factor GTPase family Q9BX10
Septin-2 (SEPTIN2) Septin GTPase family Q15019
Septin-6 (SEPTIN6) Septin GTPase family Q14141
E3 ubiquitin-protein ligase TRIM22 (TRIM22) TRIM/RBCC family Q8IYM9
Probable tRNA(His) guanylyltransferase (THG1L) TRNA(His) guanylyltransferase family Q9NWX6
Ubiquitin-conjugating enzyme E2 Z (UBE2Z) Ubiquitin-conjugating enzyme family Q9H832
UTP--glucose-1-phosphate uridylyltransferase (UGP2) UDPGP type 1 family Q16851
Ceramide kinase (CERK) . Q8TCT0
FAD-linked sulfhydryl oxidase ALR (GFER) . P55789
SET-binding protein (SETBP1) . Q9Y6X0
Transporter and channel
Click To Hide/Show 9 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Anoctamin-9 (ANO9) Anoctamin family A1A5B4
Cytochrome c oxidase subunit 5B, mitochondrial (COX5B) Cytochrome c oxidase subunit 5B family P10606
P2X purinoceptor 7 (P2RX7) P2X receptor family Q99572
Prenylated Rab acceptor protein 1 (RABAC1) PRA1 family Q9UI14
Protein S100-A1 (S100A1) S-100 family P23297
Voltage-gated potassium channel subunit beta-3 (KCNAB3) Shaker potassium channel beta subunit family O43448
Translocating chain-associated membrane protein 1-like 1 (TRAM1L1) TRAM family Q8N609
TP53-regulated inhibitor of apoptosis 1 (TRIAP1) TRIAP1/MDM35 family O43715
SEC14-like protein 4 (SEC14L4) . Q9UDX3
Transcription factor
Click To Hide/Show 11 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
BarH-like 2 homeobox protein (BARHL2) BAR homeobox family Q9NY43
Doublesex- and mab-3-related transcription factor 3 (DMRT3) DMRT family Q9NQL9
Zinc finger protein 165 (ZNF165) Krueppel C2H2-type zinc-finger protein family P49910
Zinc finger protein 398 (ZNF398) Krueppel C2H2-type zinc-finger protein family Q8TD17
Zinc finger protein 439 (ZNF439) Krueppel C2H2-type zinc-finger protein family Q8NDP4
Protein max (MAX) MAX family P61244
Retinoic acid receptor alpha (RARA) Nuclear hormone receptor family P10276
Transcriptional repressor protein YY1 (YY1) YY transcription factor family P25490
THAP domain-containing protein 10 (THAP10) . Q9P2Z0
Zinc finger and BTB domain-containing protein 6 (ZBTB6) . Q15916
Zinc finger protein 581 (ZNF581) . Q9P0T4
GPCR
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Chemokine XC receptor 1 (XCR1) G-protein coupled receptor 1 family P46094
Other
Click To Hide/Show 60 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
BCAS3 microtubule associated cell migration factor (BCAS3) BCAS3 family Q9H6U6
Beta-crystallin A3 (CRYBA1) Beta/gamma-crystallin family P05813
Biogenesis of lysosome-related organelles complex 1 subunit 6 (BLOC1S6) BLOC1S6 family Q9UL45
cAMP-dependent protein kinase type I-alpha regulatory subunit (PRKAR1A) CAMP-dependent kinase regulatory chain family P10644
Coiled-coil domain-containing protein 25 (CCDC25) CCDC25 family Q86WR0
Cysteine-rich hydrophobic domain-containing protein 2 (CHIC2) CHIC family Q9UKJ5
Dedicator of cytokinesis protein 2 (DOCK2) DOCK family Q92608
Dedicator of cytokinesis protein 3 (DOCK3) DOCK family Q8IZD9
Chromatin modification-related protein MEAF6 (MEAF6) EAF6 family Q9HAF1
Eukaryotic translation initiation factor 3 subunit C (EIF3C) EIF-3 subunit C family Q99613
Small ribosomal subunit protein eS21 (RPS21) Eukaryotic ribosomal protein eS21 family P63220
F-box/WD repeat-containing protein 5 (FBXW5) FBXW5 family Q969U6
Heme-binding protein 2 (HEBP2) HEBP family Q9Y5Z4
Fibroblast growth factor 13 (FGF13) Heparin-binding growth factors family Q92913
KH domain-containing protein 3 (KHDC3L) KHDC1 family Q587J8
Keratin-associated protein 10-10 (KRTAP10-10) KRTAP type 10 family P60014
Keratin-associated protein 5-4 (KRTAP5-4) KRTAP type 5 family Q6L8H1
Protein LDOC1 (LDOC1) LDOC1 family O95751
Microfibrillar-associated protein 1 (MFAP1) MFAP1 family P55081
Nucleoplasmin-2 (NPM2) Nucleoplasmin family Q86SE8
Protein kinase C and casein kinase substrate in neurons protein 1 (PACSIN1) PACSIN family Q9BY11
Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) PI3K p85 subunit family Q92569
R-spondin-2 (RSPO2) R-spondin family Q6UXX9
Protein reprimo (RPRM) Reprimo family Q9NS64
Protein S100-A13 (S100A13) S-100 family Q99584
Sclerostin (SOST) Sclerostin family Q9BQB4
Heat shock protein beta-7 (HSPB7) Small heat shock protein (HSP20) family Q9UBY9
Pre-mRNA-splicing factor SPF27 (BCAS2) SPF27 family O75934
Synaptotagmin-16 (SYT16) Synaptotagmin family Q17RD7
Dynein axonemal assembly factor 11 (DNAAF11) TilB family Q86X45
Tumor necrosis factor alpha-induced protein 8 (TNFAIP8) TNFAIP8 family O95379
Tumor necrosis factor alpha-induced protein 8-like protein 1 (TNFAIP8L1) TNFAIP8 family Q8WVP5
Trafficking protein particle complex subunit 3 (TRAPPC3) TRAPP small subunits family O43617
Tetratricopeptide repeat protein 9C (TTC9C) TTC9 family Q8N5M4
Vasculin (GPBP1) Vasculin family Q86WP2
Protein YIF1A (YIF1A) YIF1 family O95070
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) . Q13155
Arf-GAP with dual PH domain-containing protein 1 (ADAP1) . O75689
Bromodomain-containing protein 7 (BRD7) . Q9NPI1
Centrosomal protein of 44 kDa (CEP44) . Q9C0F1
Chromobox protein homolog 8 (CBX8) . Q9HC52
Coiled-coil domain-containing protein 146 (CCDC146) . Q8IYE0
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 (CHCHD2) . Q9Y6H1
Complement C3 (C3) . P01024
DAZ-associated protein 2 (DAZAP2) . Q15038
F-box only protein 28 (FBXO28) . Q9NVF7
FERM domain-containing protein 8 (FRMD8) . Q9BZ67
GRAM domain-containing protein 4 (GRAMD4) . Q6IC98
Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3) . Q96JM7
MAP3K12-binding inhibitory protein 1 (MBIP) . Q9NS73
Midnolin (MIDN) . Q504T8
Multiple myeloma tumor-associated protein 2 (MMTAG2) . Q9BU76
p21-activated protein kinase-interacting protein 1 (PAK1IP1) . Q9NWT1
Phostensin (PPP1R18) . Q6NYC8
Regulator of G-protein signaling 10 (RGS10) . O43665
Spondin-2 (SPON2) . Q9BUD6
Sterile alpha motif domain-containing protein 11 (SAMD11) . Q96NU1
Telethonin (TCAP) . O15273
Tubulin-specific chaperone cofactor E-like protein (TBCEL) . Q5QJ74
Uncharacterized protein KCNJ5-AS1 (KCNJ5-AS1) . Q8TAV5

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
4 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
5 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
6 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
7 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
8 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
9 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
10 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578