Details of the Target

General Information of Target

Target ID LDTP08771
Target Name Zinc finger protein 687 (ZNF687)
Gene Name ZNF687
Gene ID 57592
Synonyms
KIAA1441; Zinc finger protein 687
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAG
DGPGVPAQASDHGLPPPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGP
HRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPS
APSPTREGALTPPPFPSSFELAQENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSG
SSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASPKVPVCQPLKEEDDDEGPVDKSSPG
SPQSPSSGAEAADEDSNDSPASSSSRPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLA
EGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVA
RKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTAT
GPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLSPPAEAGLALPPTGYRCLECGD
AFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMR
PVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTE
PPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSF
SAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNSIK
SHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQTQQAKLIYKCAMCDTVFTHKP
LLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRLEETAGKGAGGALLT
PKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRRELGSKGLKGGGGGP
GGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIK
RVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRR
QSSDSCSEEPDSTTPPAKSPRGGPGSGGHGPLRYRSSSSTEQSLMMGLRVEDGAQQCLDC
GLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGGDSPLPASGGPL
TCKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Cytoplasm
Function May be involved in transcriptional regulation.
Uniprot ID
Q8N1G0
Ensemble ID
ENST00000324048.9
HGNC ID
HGNC:29277

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
AN3CA Deletion: p.P960LfsTer23 DBIA    Probe Info 
CAL51 Deletion: p.H733MfsTer30
SNV: p.M712T		 DBIA    Probe Info 
DU145 SNV: p.T488I .
FADU SNV: p.G961E .
HCT15 SNV: p.L1215P DBIA    Probe Info 
KMCH1 SNV: p.A699V DBIA    Probe Info 
LNCaP clone FGC Deletion: p.H733MfsTer30 DBIA    Probe Info 
MEWO SNV: p.P194S DBIA    Probe Info 
MFE319 Deletion: p.G153AfsTer38 DBIA    Probe Info 
MOLT4 SNV: p.A55T; p.G1059A IA-alkyne    Probe Info 
NCIH1792 SNV: p.K264N DBIA    Probe Info 
OVK18 Deletion: p.H733MfsTer30 DBIA    Probe Info 
P31FUJ SNV: p.E1131K DBIA    Probe Info 
SBC5 SNV: p.P261S DBIA    Probe Info 
SW1573 SNV: p.C735Y DBIA    Probe Info 
TC71 SNV: p.S469L DBIA    Probe Info 
TOV21G SNV: p.Q610H DBIA    Probe Info 
U2OS SNV: p.F16V .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 9 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
AHL-Pu-1
 Probe Info  		C755(6.13)  LDD0170  [2]
DBIA
 Probe Info  		C707(1.06); C710(1.06); C91(0.99)  LDD0078  [3]
IA-alkyne
 Probe Info  		N.A.  LDD0162  [4]
IPM
 Probe Info  		N.A.  LDD0025  [5]
TFBX
 Probe Info  		C718(0.00); C1028(0.00); C755(0.00)  LDD0148  [5]
VSF
 Probe Info  		N.A.  LDD0007  [6]
Phosphinate-6
 Probe Info  		C1137(0.00); C91(0.00)  LDD0018  [7]
NAIA_5
 Probe Info  		C718(0.00); C755(0.00); C576(0.00)  LDD2223  [8]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA DM93 C755(6.13)  LDD0170  [2]
 LDCM0026  4SU-RNA+native RNA DM93 C672(2.39)  LDD0171  [2]
 LDCM0214  AC1 HCT 116 C1003(1.28); C339(1.14); C563(1.13); C566(1.13)  LDD0531  [3]
 LDCM0215  AC10 HCT 116 C1003(1.03); C535(0.88); C538(0.88); C563(1.11)  LDD0532  [3]
 LDCM0216  AC100 HCT 116 C1003(1.14); C339(0.80); C535(0.90); C538(0.90)  LDD0533  [3]
 LDCM0217  AC101 HCT 116 C1003(1.19); C339(0.88); C535(0.92); C538(0.92)  LDD0534  [3]
 LDCM0218  AC102 HCT 116 C1003(1.02); C339(0.81); C535(0.87); C538(0.87)  LDD0535  [3]
 LDCM0219  AC103 HCT 116 C1003(1.30); C339(1.04); C535(0.81); C538(0.81)  LDD0536  [3]
 LDCM0220  AC104 HCT 116 C1003(1.44); C339(0.73); C535(0.91); C538(0.91)  LDD0537  [3]
 LDCM0221  AC105 HCT 116 C1003(1.20); C339(1.13); C535(0.89); C538(0.89)  LDD0538  [3]
 LDCM0222  AC106 HCT 116 C1003(1.21); C339(1.06); C535(0.83); C538(0.83)  LDD0539  [3]
 LDCM0223  AC107 HCT 116 C1003(1.26); C339(1.08); C535(0.84); C538(0.84)  LDD0540  [3]
 LDCM0224  AC108 HCT 116 C1003(0.96); C339(0.87); C535(0.87); C538(0.87)  LDD0541  [3]
 LDCM0225  AC109 HCT 116 C1003(0.98); C339(0.82); C535(0.95); C538(0.95)  LDD0542  [3]
 LDCM0226  AC11 HCT 116 C1003(1.36); C535(0.88); C538(0.88); C563(1.24)  LDD0543  [3]
 LDCM0227  AC110 HCT 116 C1003(0.97); C339(0.78); C535(0.89); C538(0.89)  LDD0544  [3]
 LDCM0228  AC111 HCT 116 C1003(0.97); C339(0.72); C535(0.84); C538(0.84)  LDD0545  [3]
 LDCM0229  AC112 HCT 116 C1003(1.13); C339(0.70); C535(0.81); C538(0.81)  LDD0546  [3]
 LDCM0230  AC113 HCT 116 C1003(1.13); C339(0.68); C535(0.99); C538(0.99)  LDD0547  [3]
 LDCM0231  AC114 HCT 116 C1003(1.01); C339(1.22); C535(0.86); C538(0.86)  LDD0548  [3]
 LDCM0232  AC115 HCT 116 C1003(0.94); C339(1.12); C535(0.96); C538(0.96)  LDD0549  [3]
 LDCM0233  AC116 HCT 116 C1003(1.14); C339(1.08); C535(0.90); C538(0.90)  LDD0550  [3]
 LDCM0234  AC117 HCT 116 C1003(0.91); C339(1.02); C535(0.91); C538(0.91)  LDD0551  [3]
 LDCM0235  AC118 HCT 116 C1003(1.06); C339(0.88); C535(0.97); C538(0.97)  LDD0552  [3]
 LDCM0236  AC119 HCT 116 C1003(0.81); C339(1.02); C535(0.92); C538(0.92)  LDD0553  [3]
 LDCM0237  AC12 HCT 116 C1003(1.13); C535(0.90); C538(0.90); C563(1.16)  LDD0554  [3]
 LDCM0238  AC120 HCT 116 C1003(0.79); C339(1.07); C535(0.90); C538(0.90)  LDD0555  [3]
 LDCM0239  AC121 HCT 116 C1003(0.64); C339(0.81); C535(1.00); C538(1.00)  LDD0556  [3]
 LDCM0240  AC122 HCT 116 C1003(0.82); C339(0.94); C535(1.16); C538(1.16)  LDD0557  [3]
 LDCM0241  AC123 HCT 116 C1003(0.73); C339(0.74); C535(1.05); C538(1.05)  LDD0558  [3]
 LDCM0242  AC124 HCT 116 C1003(0.82); C339(0.87); C535(0.99); C538(0.99)  LDD0559  [3]
 LDCM0243  AC125 HCT 116 C1003(0.79); C339(1.00); C535(1.02); C538(1.02)  LDD0560  [3]
 LDCM0244  AC126 HCT 116 C1003(0.90); C339(1.10); C535(0.91); C538(0.91)  LDD0561  [3]
 LDCM0245  AC127 HCT 116 C1003(0.91); C339(0.88); C535(0.91); C538(0.91)  LDD0562  [3]
 LDCM0246  AC128 HCT 116 C339(0.23); C535(1.14); C538(1.14); C563(1.16)  LDD0563  [3]
 LDCM0247  AC129 HCT 116 C339(0.25); C535(1.04); C538(1.04); C563(1.04)  LDD0564  [3]
 LDCM0249  AC130 HCT 116 C339(0.34); C535(0.87); C538(0.87); C563(1.12)  LDD0566  [3]
 LDCM0250  AC131 HCT 116 C339(0.22); C535(1.18); C538(1.18); C563(1.11)  LDD0567  [3]
 LDCM0251  AC132 HCT 116 C339(0.22); C535(1.17); C538(1.17); C563(1.16)  LDD0568  [3]
 LDCM0252  AC133 HCT 116 C339(0.27); C535(0.99); C538(0.99); C563(1.13)  LDD0569  [3]
 LDCM0253  AC134 HCT 116 C339(0.28); C535(0.92); C538(0.92); C563(1.15)  LDD0570  [3]
 LDCM0254  AC135 HCT 116 C339(0.35); C535(1.24); C538(1.24); C563(1.22)  LDD0571  [3]
 LDCM0255  AC136 HCT 116 C339(0.26); C535(0.99); C538(0.99); C563(1.08)  LDD0572  [3]
 LDCM0256  AC137 HCT 116 C339(0.20); C535(0.83); C538(0.83); C563(1.15)  LDD0573  [3]
 LDCM0257  AC138 HCT 116 C339(0.23); C535(0.85); C538(0.85); C563(1.16)  LDD0574  [3]
 LDCM0258  AC139 HCT 116 C339(0.30); C535(0.98); C538(0.98); C563(1.00)  LDD0575  [3]
 LDCM0259  AC14 HCT 116 C1003(0.87); C535(1.02); C538(1.02); C563(1.04)  LDD0576  [3]
 LDCM0260  AC140 HCT 116 C339(0.38); C535(0.90); C538(0.90); C563(1.14)  LDD0577  [3]
 LDCM0261  AC141 HCT 116 C339(0.31); C535(0.79); C538(0.79); C563(1.16)  LDD0578  [3]
 LDCM0262  AC142 HCT 116 C339(0.28); C535(0.93); C538(0.93); C563(1.42)  LDD0579  [3]
 LDCM0263  AC143 HCT 116 C339(0.83); C563(0.95); C566(0.95); C1003(0.98)  LDD0580  [3]
 LDCM0264  AC144 HCT 116 C563(0.82); C566(0.82); C707(0.91); C766(0.94)  LDD0581  [3]
 LDCM0265  AC145 HCT 116 C339(0.71); C563(0.74); C566(0.74); C766(0.92)  LDD0582  [3]
 LDCM0266  AC146 HCT 116 C563(0.80); C566(0.80); C339(0.86); C710(0.87)  LDD0583  [3]
 LDCM0267  AC147 HCT 116 C339(0.67); C563(0.72); C566(0.72); C766(0.89)  LDD0584  [3]
 LDCM0268  AC148 HCT 116 C339(0.76); C563(0.79); C566(0.79); C766(0.82)  LDD0585  [3]
 LDCM0269  AC149 HCT 116 C339(0.65); C766(0.94); C769(0.94); C563(0.94)  LDD0586  [3]
 LDCM0270  AC15 HCT 116 C829(0.74); C832(0.74); C566(0.84); C535(0.84)  LDD0587  [3]
 LDCM0271  AC150 HCT 116 C563(0.68); C566(0.68); C535(0.81); C538(0.81)  LDD0588  [3]
 LDCM0272  AC151 HCT 116 C563(0.83); C566(0.83); C535(0.88); C538(0.88)  LDD0589  [3]
 LDCM0273  AC152 HCT 116 C339(0.57); C563(0.74); C566(0.74); C710(0.84)  LDD0590  [3]
 LDCM0274  AC153 HCT 116 C339(0.49); C563(0.92); C566(0.92); C766(0.96)  LDD0591  [3]
 LDCM0621  AC154 HCT 116 C1003(1.04); C339(0.50); C535(1.04); C538(1.04)  LDD2158  [3]
 LDCM0622  AC155 HCT 116 C1003(1.01); C339(0.60); C535(1.07); C538(1.07)  LDD2159  [3]
 LDCM0623  AC156 HCT 116 C1003(1.07); C339(0.45); C535(1.03); C538(1.03)  LDD2160  [3]
 LDCM0624  AC157 HCT 116 C1003(1.06); C339(0.44); C535(0.97); C538(0.97)  LDD2161  [3]
 LDCM0276  AC17 HCT 116 C339(0.73); C829(0.82); C832(0.82); C735(0.87)  LDD0593  [3]
 LDCM0277  AC18 HCT 116 C339(0.68); C829(0.81); C832(0.81); C735(0.84)  LDD0594  [3]
 LDCM0278  AC19 HCT 116 C339(0.62); C829(0.81); C832(0.81); C1003(0.85)  LDD0595  [3]
 LDCM0279  AC2 HCT 116 C594(0.88); C563(0.93); C566(0.93); C735(1.17)  LDD0596  [3]
 LDCM0280  AC20 HCT 116 C339(0.64); C566(0.73); C594(0.74); C563(0.76)  LDD0597  [3]
 LDCM0281  AC21 HCT 116 C339(0.54); C594(0.84); C829(0.84); C832(0.84)  LDD0598  [3]
 LDCM0282  AC22 HCT 116 C339(0.54); C566(0.76); C829(0.79); C832(0.79)  LDD0599  [3]
 LDCM0283  AC23 HCT 116 C339(0.49); C566(0.72); C563(0.73); C829(0.80)  LDD0600  [3]
 LDCM0284  AC24 HCT 116 C339(0.65); C829(0.70); C832(0.70); C566(0.73)  LDD0601  [3]
 LDCM0285  AC25 HCT 116 C535(0.54); C538(0.54); C563(0.72); C566(0.72)  LDD0602  [3]
 LDCM0286  AC26 HCT 116 C563(0.83); C566(0.83); C535(0.92); C538(0.92)  LDD0603  [3]
 LDCM0287  AC27 HCT 116 C535(0.43); C538(0.43); C563(0.72); C566(0.72)  LDD0604  [3]
 LDCM0288  AC28 HCT 116 C535(0.41); C538(0.41); C563(0.92); C566(0.92)  LDD0605  [3]
 LDCM0289  AC29 HCT 116 C535(0.62); C538(0.62); C563(0.69); C566(0.69)  LDD0606  [3]
 LDCM0290  AC3 HCT 116 C594(0.91); C1003(1.21); C735(1.22); C738(1.22)  LDD0607  [3]
 LDCM0291  AC30 HCT 116 C535(0.66); C538(0.66); C563(0.68); C566(0.68)  LDD0608  [3]
 LDCM0292  AC31 HCT 116 C535(0.72); C538(0.72); C563(0.83); C566(0.83)  LDD0609  [3]
 LDCM0293  AC32 HCT 116 C535(0.65); C538(0.65); C563(0.75); C566(0.75)  LDD0610  [3]
 LDCM0294  AC33 HCT 116 C535(0.44); C538(0.44); C563(0.58); C566(0.58)  LDD0611  [3]
 LDCM0295  AC34 HCT 116 C563(0.44); C566(0.44); C535(0.44); C538(0.44)  LDD0612  [3]
 LDCM0296  AC35 HCT 116 C735(0.76); C738(0.76); C594(0.84); C1003(1.00)  LDD0613  [3]
 LDCM0297  AC36 HCT 116 C594(0.96); C735(0.97); C738(0.97); C829(0.97)  LDD0614  [3]
 LDCM0298  AC37 HCT 116 C563(0.94); C566(0.94); C1003(0.96); C735(0.98)  LDD0615  [3]
 LDCM0299  AC38 HCT 116 C829(0.86); C832(0.86); C594(0.91); C735(1.01)  LDD0616  [3]
 LDCM0300  AC39 HCT 116 C735(0.76); C738(0.76); C829(0.94); C832(0.94)  LDD0617  [3]
 LDCM0301  AC4 HCT 116 C563(0.89); C566(0.89); C594(0.99); C1003(1.17)  LDD0618  [3]
 LDCM0302  AC40 HCT 116 C535(0.90); C538(0.90); C829(0.96); C832(0.96)  LDD0619  [3]
 LDCM0303  AC41 HCT 116 C735(0.86); C738(0.86); C535(0.89); C538(0.89)  LDD0620  [3]
 LDCM0304  AC42 HCT 116 C535(0.90); C538(0.90); C735(0.92); C738(0.92)  LDD0621  [3]
 LDCM0305  AC43 HCT 116 C563(0.97); C566(0.97); C735(0.98); C738(0.98)  LDD0622  [3]
 LDCM0306  AC44 HCT 116 C829(0.87); C832(0.87); C535(0.97); C538(0.97)  LDD0623  [3]
 LDCM0307  AC45 HCT 116 C829(0.71); C832(0.71); C535(0.93); C538(0.93)  LDD0624  [3]
 LDCM0308  AC46 HCT 116 C566(0.78); C707(1.03); C710(1.03); C594(1.07)  LDD0625  [3]
 LDCM0309  AC47 HCT 116 C707(0.56); C710(0.56); C566(0.87); C594(0.97)  LDD0626  [3]
 LDCM0310  AC48 HCT 116 C707(0.35); C710(0.35); C594(0.89); C566(0.96)  LDD0627  [3]
 LDCM0311  AC49 HCT 116 C566(0.61); C535(0.89); C538(0.89); C707(0.91)  LDD0628  [3]
 LDCM0312  AC5 HCT 116 C594(0.96); C563(1.08); C566(1.08); C735(1.18)  LDD0629  [3]
 LDCM0313  AC50 HCT 116 C566(0.80); C535(0.87); C538(0.87); C594(1.04)  LDD0630  [3]
 LDCM0314  AC51 HCT 116 C707(0.55); C710(0.55); C566(0.56); C535(1.04)  LDD0631  [3]
 LDCM0315  AC52 HCT 116 C707(0.43); C710(0.43); C566(0.70); C535(0.81)  LDD0632  [3]
 LDCM0316  AC53 HCT 116 C566(0.71); C535(0.90); C538(0.90); C707(0.91)  LDD0633  [3]
 LDCM0317  AC54 HCT 116 C566(0.80); C535(0.87); C538(0.87); C594(0.99)  LDD0634  [3]
 LDCM0318  AC55 HCT 116 C707(0.63); C710(0.63); C566(0.80); C535(0.91)  LDD0635  [3]
 LDCM0319  AC56 HCT 116 C566(0.68); C594(0.93); C1003(0.96); C535(1.12)  LDD0636  [3]
 LDCM0320  AC57 HCT 116 C829(0.56); C832(0.56); C535(0.67); C538(0.67)  LDD0637  [3]
 LDCM0321  AC58 HCT 116 C829(0.55); C832(0.55); C535(0.67); C538(0.67)  LDD0638  [3]
 LDCM0322  AC59 HCT 116 C829(0.49); C832(0.49); C535(0.68); C538(0.68)  LDD0639  [3]
 LDCM0323  AC6 HCT 116 C535(0.86); C538(0.86); C829(0.90); C832(0.90)  LDD0640  [3]
 LDCM0324  AC60 HCT 116 C829(0.50); C832(0.50); C535(0.80); C538(0.80)  LDD0641  [3]
 LDCM0325  AC61 HCT 116 C829(0.86); C832(0.86); C1003(0.91); C594(1.00)  LDD0642  [3]
 LDCM0326  AC62 HCT 116 C829(0.38); C832(0.38); C535(0.67); C538(0.67)  LDD0643  [3]
 LDCM0327  AC63 HCT 116 C535(0.73); C538(0.73); C594(0.85); C829(0.91)  LDD0644  [3]
 LDCM0328  AC64 HCT 116 C829(0.63); C832(0.63); C535(0.67); C538(0.67)  LDD0645  [3]
 LDCM0329  AC65 HCT 116 C535(0.60); C538(0.60); C594(1.04); C566(1.08)  LDD0646  [3]
 LDCM0330  AC66 HCT 116 C829(0.58); C832(0.58); C535(0.63); C538(0.63)  LDD0647  [3]
 LDCM0331  AC67 HCT 116 C535(0.53); C538(0.53); C829(0.70); C832(0.70)  LDD0648  [3]
 LDCM0332  AC68 HCT 116 C829(0.77); C832(0.77); C339(0.89); C707(0.91)  LDD0649  [3]
 LDCM0333  AC69 HCT 116 C829(0.73); C832(0.73); C594(0.92); C707(0.93)  LDD0650  [3]
 LDCM0334  AC7 HCT 116 C594(0.85); C829(0.88); C832(0.88); C1003(0.95)  LDD0651  [3]
 LDCM0335  AC70 HCT 116 C829(0.59); C832(0.59); C535(0.80); C538(0.80)  LDD0652  [3]
 LDCM0336  AC71 HCT 116 C829(0.78); C832(0.78); C707(0.83); C710(0.83)  LDD0653  [3]
 LDCM0337  AC72 HCT 116 C829(0.75); C832(0.75); C535(0.86); C538(0.86)  LDD0654  [3]
 LDCM0338  AC73 HCT 116 C829(0.75); C832(0.75); C766(0.92); C769(0.92)  LDD0655  [3]
 LDCM0339  AC74 HCT 116 C829(0.81); C832(0.81); C535(1.04); C538(1.04)  LDD0656  [3]
 LDCM0340  AC75 HCT 116 C829(0.67); C832(0.67); C766(0.86); C769(0.86)  LDD0657  [3]
 LDCM0341  AC76 HCT 116 C829(0.70); C832(0.70); C535(0.95); C538(0.95)  LDD0658  [3]
 LDCM0342  AC77 HCT 116 C829(0.81); C832(0.81); C707(0.95); C710(0.95)  LDD0659  [3]
 LDCM0343  AC78 HCT 116 C829(0.72); C832(0.72); C707(0.87); C710(0.87)  LDD0660  [3]
 LDCM0344  AC79 HCT 116 C829(0.66); C832(0.66); C535(0.83); C538(0.83)  LDD0661  [3]
 LDCM0345  AC8 HCT 116 C735(0.77); C738(0.77); C829(0.81); C832(0.81)  LDD0662  [3]
 LDCM0346  AC80 HCT 116 C829(0.65); C832(0.65); C535(0.86); C538(0.86)  LDD0663  [3]
 LDCM0347  AC81 HCT 116 C829(0.69); C832(0.69); C735(0.89); C738(0.89)  LDD0664  [3]
 LDCM0348  AC82 HCT 116 C829(0.60); C832(0.60); C766(0.95); C769(0.95)  LDD0665  [3]
 LDCM0349  AC83 HCT 116 C563(0.60); C566(0.60); C766(0.73); C769(0.73)  LDD0666  [3]
 LDCM0350  AC84 HCT 116 C563(0.70); C566(0.70); C766(0.81); C769(0.81)  LDD0667  [3]
 LDCM0351  AC85 HCT 116 C563(0.70); C566(0.70); C535(0.88); C538(0.88)  LDD0668  [3]
 LDCM0352  AC86 HCT 116 C563(0.67); C566(0.67); C535(0.72); C538(0.72)  LDD0669  [3]
 LDCM0353  AC87 HCT 116 C339(0.82); C766(0.93); C769(0.93); C594(0.99)  LDD0670  [3]
 LDCM0354  AC88 HCT 116 C563(0.70); C566(0.70); C766(0.75); C769(0.75)  LDD0671  [3]
 LDCM0355  AC89 HCT 116 C563(0.61); C566(0.61); C339(0.82); C535(0.86)  LDD0672  [3]
 LDCM0357  AC90 HCT 116 C563(0.70); C566(0.70); C339(0.95); C535(0.98)  LDD0674  [3]
 LDCM0358  AC91 HCT 116 C563(0.60); C566(0.60); C766(0.70); C769(0.70)  LDD0675  [3]
 LDCM0359  AC92 HCT 116 C563(0.60); C566(0.60); C766(0.74); C769(0.74)  LDD0676  [3]
 LDCM0360  AC93 HCT 116 C563(0.66); C566(0.66); C766(0.78); C769(0.78)  LDD0677  [3]
 LDCM0361  AC94 HCT 116 C339(0.65); C563(0.66); C566(0.66); C766(0.74)  LDD0678  [3]
 LDCM0362  AC95 HCT 116 C563(0.74); C566(0.74); C339(0.87); C735(0.99)  LDD0679  [3]
 LDCM0363  AC96 HCT 116 C339(0.69); C563(0.74); C566(0.74); C766(0.86)  LDD0680  [3]
 LDCM0364  AC97 HCT 116 C563(0.62); C566(0.62); C766(0.78); C769(0.78)  LDD0681  [3]
 LDCM0365  AC98 HCT 116 C707(0.58); C710(0.58); C535(0.85); C538(0.85)  LDD0682  [3]
 LDCM0366  AC99 HCT 116 C707(0.46); C710(0.46); C535(0.84); C538(0.84)  LDD0683  [3]
 LDCM0248  AKOS034007472 HCT 116 C1003(1.06); C535(1.02); C538(1.02); C563(1.11)  LDD0565  [3]
 LDCM0356  AKOS034007680 HCT 116 C829(0.80); C832(0.80); C594(0.84); C535(0.92)  LDD0673  [3]
 LDCM0275  AKOS034007705 HCT 116 C829(0.73); C832(0.73); C566(0.87); C535(0.89)  LDD0592  [3]
 LDCM0156  Aniline NCI-H1299 11.45  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C707(1.06); C710(1.06); C91(0.99)  LDD0078  [3]
 LDCM0102  BDHI 8 Jurkat C1003(8.80)  LDD0204  [9]
 LDCM0632  CL-Sc Hep-G2 C91(20.00)  LDD2227  [8]
 LDCM0367  CL1 HCT 116 C535(0.53); C538(0.53); C735(0.73); C738(0.73)  LDD0684  [3]
 LDCM0368  CL10 HCT 116 C535(0.55); C538(0.55); C1003(0.82); C829(0.88)  LDD0685  [3]
 LDCM0369  CL100 HCT 116 C594(0.91); C563(0.95); C566(0.95); C1003(1.12)  LDD0686  [3]
 LDCM0370  CL101 HCT 116 C829(0.74); C832(0.74); C594(0.89); C1003(0.93)  LDD0687  [3]
 LDCM0371  CL102 HCT 116 C829(0.68); C832(0.68); C594(0.90); C1003(0.95)  LDD0688  [3]
 LDCM0372  CL103 HCT 116 C829(0.71); C832(0.71); C594(0.82); C535(0.97)  LDD0689  [3]
 LDCM0373  CL104 HCT 116 C829(0.79); C832(0.79); C594(0.88); C535(0.92)  LDD0690  [3]
 LDCM0374  CL105 HCT 116 C339(0.51); C829(0.80); C832(0.80); C566(0.85)  LDD0691  [3]
 LDCM0375  CL106 HCT 116 C339(0.57); C566(0.82); C594(0.82); C829(0.91)  LDD0692  [3]
 LDCM0376  CL107 HCT 116 C339(0.48); C829(0.73); C832(0.73); C566(0.76)  LDD0693  [3]
 LDCM0377  CL108 HCT 116 C339(0.55); C566(0.59); C563(0.77); C735(0.86)  LDD0694  [3]
 LDCM0378  CL109 HCT 116 C829(0.65); C832(0.65); C566(0.79); C735(0.87)  LDD0695  [3]
 LDCM0379  CL11 HCT 116 C535(0.65); C538(0.65); C735(0.74); C738(0.74)  LDD0696  [3]
 LDCM0380  CL110 HCT 116 C339(0.53); C566(0.79); C829(0.84); C832(0.84)  LDD0697  [3]
 LDCM0381  CL111 HCT 116 C339(0.51); C735(0.81); C738(0.81); C829(0.83)  LDD0698  [3]
 LDCM0382  CL112 HCT 116 C535(0.50); C538(0.50); C563(0.66); C566(0.66)  LDD0699  [3]
 LDCM0383  CL113 HCT 116 C535(0.41); C538(0.41); C563(0.50); C566(0.50)  LDD0700  [3]
 LDCM0384  CL114 HCT 116 C535(0.44); C538(0.44); C563(0.52); C566(0.52)  LDD0701  [3]
 LDCM0385  CL115 HCT 116 C535(0.42); C538(0.42); C563(0.61); C566(0.61)  LDD0702  [3]
 LDCM0386  CL116 HCT 116 C563(0.59); C566(0.59); C535(0.68); C538(0.68)  LDD0703  [3]
 LDCM0387  CL117 HCT 116 C829(0.65); C832(0.65); C535(0.99); C538(0.99)  LDD0704  [3]
 LDCM0388  CL118 HCT 116 C735(0.90); C738(0.90); C535(0.94); C538(0.94)  LDD0705  [3]
 LDCM0389  CL119 HCT 116 C735(0.87); C738(0.87); C829(0.91); C832(0.91)  LDD0706  [3]
 LDCM0390  CL12 HCT 116 C1003(0.77); C535(0.84); C538(0.84); C563(0.91)  LDD0707  [3]
 LDCM0391  CL120 HCT 116 C735(0.79); C738(0.79); C829(0.79); C832(0.79)  LDD0708  [3]
 LDCM0392  CL121 HCT 116 C707(0.73); C710(0.73); C566(0.89); C1003(1.11)  LDD0709  [3]
 LDCM0393  CL122 HCT 116 C566(0.70); C535(0.86); C538(0.86); C707(0.92)  LDD0710  [3]
 LDCM0394  CL123 HCT 116 C707(0.50); C710(0.50); C566(0.67); C535(0.86)  LDD0711  [3]
 LDCM0395  CL124 HCT 116 C707(0.54); C710(0.54); C566(0.80); C535(0.85)  LDD0712  [3]
 LDCM0396  CL125 HCT 116 C735(0.79); C738(0.79); C829(0.82); C832(0.82)  LDD0713  [3]
 LDCM0397  CL126 HCT 116 C829(0.43); C832(0.43); C566(0.93); C594(0.95)  LDD0714  [3]
 LDCM0398  CL127 HCT 116 C829(0.35); C832(0.35); C535(0.71); C538(0.71)  LDD0715  [3]
 LDCM0399  CL128 HCT 116 C829(0.59); C832(0.59); C535(0.76); C538(0.76)  LDD0716  [3]
 LDCM0400  CL13 HCT 116 C1003(0.80); C535(0.89); C538(0.89); C563(0.98)  LDD0717  [3]
 LDCM0401  CL14 HCT 116 C535(0.73); C538(0.73); C1003(0.82); C563(0.93)  LDD0718  [3]
 LDCM0402  CL15 HCT 116 C829(0.84); C832(0.84); C1003(0.97); C735(1.00)  LDD0719  [3]
 LDCM0403  CL16 HCT 116 C339(0.94); C1003(1.02); C563(1.04); C566(1.04)  LDD0720  [3]
 LDCM0404  CL17 HCT 116 C563(0.84); C566(0.84); C707(0.92); C710(0.92)  LDD0721  [3]
 LDCM0405  CL18 HCT 116 C594(1.09); C563(1.12); C566(1.12); C829(1.31)  LDD0722  [3]
 LDCM0406  CL19 HCT 116 C563(0.98); C566(0.98); C594(0.98); C1003(1.02)  LDD0723  [3]
 LDCM0407  CL2 HCT 116 C735(0.63); C738(0.63); C594(0.80); C1003(0.88)  LDD0724  [3]
 LDCM0408  CL20 HCT 116 C563(1.03); C566(1.03); C594(1.15); C735(1.19)  LDD0725  [3]
 LDCM0409  CL21 HCT 116 C563(1.01); C566(1.01); C707(1.06); C710(1.06)  LDD0726  [3]
 LDCM0410  CL22 HCT 116 C594(1.00); C707(1.07); C710(1.07); C1003(1.09)  LDD0727  [3]
 LDCM0411  CL23 HCT 116 C1003(0.76); C563(0.93); C566(0.93); C594(1.21)  LDD0728  [3]
 LDCM0412  CL24 HCT 116 C1003(0.89); C563(0.87); C566(0.87); C594(1.05)  LDD0729  [3]
 LDCM0413  CL25 HCT 116 C1003(0.79); C563(1.01); C566(1.01); C594(1.31)  LDD0730  [3]
 LDCM0414  CL26 HCT 116 C1003(1.14); C563(0.98); C566(0.98); C594(1.06)  LDD0731  [3]
 LDCM0415  CL27 HCT 116 C1003(0.79); C563(1.01); C566(1.01); C594(1.13)  LDD0732  [3]
 LDCM0416  CL28 HCT 116 C1003(0.81); C563(1.02); C566(1.02); C594(1.20)  LDD0733  [3]
 LDCM0417  CL29 HCT 116 C1003(0.74); C563(0.95); C566(0.95); C594(1.12)  LDD0734  [3]
 LDCM0418  CL3 HCT 116 C1003(0.82); C339(1.41); C535(0.98); C538(0.98)  LDD0735  [3]
 LDCM0419  CL30 HCT 116 C1003(0.96); C563(1.10); C566(1.10); C594(1.48)  LDD0736  [3]
 LDCM0420  CL31 HCT 116 C1003(1.15); C535(0.80); C538(0.80); C563(0.75)  LDD0737  [3]
 LDCM0421  CL32 HCT 116 C1003(1.01); C339(1.27); C535(1.01); C538(1.01)  LDD0738  [3]
 LDCM0422  CL33 HCT 116 C1003(1.02); C339(1.20); C535(0.84); C538(0.84)  LDD0739  [3]
 LDCM0423  CL34 HCT 116 C1003(0.95); C339(1.07); C535(0.81); C538(0.81)  LDD0740  [3]
 LDCM0424  CL35 HCT 116 C1003(1.01); C339(1.17); C535(0.77); C538(0.77)  LDD0741  [3]
 LDCM0425  CL36 HCT 116 C1003(1.00); C339(0.91); C535(0.70); C538(0.70)  LDD0742  [3]
 LDCM0426  CL37 HCT 116 C1003(0.97); C339(1.12); C535(0.78); C538(0.78)  LDD0743  [3]
 LDCM0428  CL39 HCT 116 C1003(0.96); C339(1.13); C535(0.73); C538(0.73)  LDD0745  [3]
 LDCM0429  CL4 HCT 116 C1003(0.74); C339(0.99); C535(0.58); C538(0.58)  LDD0746  [3]
 LDCM0430  CL40 HCT 116 C1003(1.00); C339(0.90); C535(0.74); C538(0.74)  LDD0747  [3]
 LDCM0431  CL41 HCT 116 C1003(0.96); C339(0.87); C535(0.79); C538(0.79)  LDD0748  [3]
 LDCM0432  CL42 HCT 116 C1003(0.83); C339(0.76); C535(0.83); C538(0.83)  LDD0749  [3]
 LDCM0433  CL43 HCT 116 C1003(0.88); C339(1.02); C535(0.72); C538(0.72)  LDD0750  [3]
 LDCM0434  CL44 HCT 116 C1003(1.03); C339(1.05); C535(0.80); C538(0.80)  LDD0751  [3]
 LDCM0435  CL45 HCT 116 C1003(1.21); C339(0.92); C535(0.79); C538(0.79)  LDD0752  [3]
 LDCM0436  CL46 HCT 116 C1003(1.08); C339(0.66); C594(1.03); C707(0.76)  LDD0753  [3]
 LDCM0437  CL47 HCT 116 C1003(0.82); C339(0.94); C594(1.04); C707(0.88)  LDD0754  [3]
 LDCM0438  CL48 HCT 116 C1003(0.99); C339(0.64); C594(0.99); C707(1.24)  LDD0755  [3]
 LDCM0439  CL49 HCT 116 C1003(1.03); C339(0.90); C594(1.10); C707(0.97)  LDD0756  [3]
 LDCM0440  CL5 HCT 116 C1003(0.90); C339(1.16); C535(0.82); C538(0.82)  LDD0757  [3]
 LDCM0441  CL50 HCT 116 C1003(1.02); C339(0.53); C594(0.97); C707(0.88)  LDD0758  [3]
 LDCM0442  CL51 HCT 116 C1003(0.93); C339(0.50); C594(1.04); C707(0.95)  LDD0759  [3]
 LDCM0443  CL52 HCT 116 C1003(1.14); C339(0.55); C594(0.94); C707(0.85)  LDD0760  [3]
 LDCM0444  CL53 HCT 116 C1003(0.99); C339(0.42); C594(1.11); C707(1.10)  LDD0761  [3]
 LDCM0445  CL54 HCT 116 C1003(0.98); C339(0.48); C594(0.98); C707(0.96)  LDD0762  [3]
 LDCM0446  CL55 HCT 116 C1003(0.84); C339(0.49); C594(0.99); C707(1.07)  LDD0763  [3]
 LDCM0447  CL56 HCT 116 C1003(1.04); C339(0.46); C594(0.96); C707(1.14)  LDD0764  [3]
 LDCM0448  CL57 HCT 116 C1003(0.91); C339(0.38); C594(1.05); C707(0.95)  LDD0765  [3]
 LDCM0449  CL58 HCT 116 C1003(1.05); C339(0.58); C594(1.03); C707(0.89)  LDD0766  [3]
 LDCM0450  CL59 HCT 116 C1003(1.04); C339(0.54); C594(1.02); C707(0.97)  LDD0767  [3]
 LDCM0451  CL6 HCT 116 C1003(0.97); C339(1.13); C535(0.92); C538(0.92)  LDD0768  [3]
 LDCM0452  CL60 HCT 116 C1003(1.06); C339(0.61); C594(1.08); C707(1.16)  LDD0769  [3]
 LDCM0453  CL61 HCT 116 C1003(1.36); C339(0.95); C535(0.89); C538(0.89)  LDD0770  [3]
 LDCM0454  CL62 HCT 116 C1003(0.96); C339(1.21); C535(0.95); C538(0.95)  LDD0771  [3]
 LDCM0455  CL63 HCT 116 C1003(1.07); C339(1.33); C535(0.92); C538(0.92)  LDD0772  [3]
 LDCM0456  CL64 HCT 116 C1003(1.46); C339(0.89); C535(0.93); C538(0.93)  LDD0773  [3]
 LDCM0457  CL65 HCT 116 C1003(1.16); C339(1.06); C535(0.93); C538(0.93)  LDD0774  [3]
 LDCM0458  CL66 HCT 116 C1003(1.60); C339(1.14); C535(0.92); C538(0.92)  LDD0775  [3]
 LDCM0459  CL67 HCT 116 C1003(1.25); C339(1.12); C535(1.06); C538(1.06)  LDD0776  [3]
 LDCM0460  CL68 HCT 116 C1003(0.94); C339(1.00); C535(0.90); C538(0.90)  LDD0777  [3]
 LDCM0461  CL69 HCT 116 C1003(0.92); C339(1.09); C535(1.26); C538(1.26)  LDD0778  [3]
 LDCM0462  CL7 HCT 116 C1003(0.99); C339(1.17); C535(1.06); C538(1.06)  LDD0779  [3]
 LDCM0463  CL70 HCT 116 C1003(1.17); C339(0.89); C535(1.08); C538(1.08)  LDD0780  [3]
 LDCM0464  CL71 HCT 116 C1003(1.22); C339(0.88); C535(0.88); C538(0.88)  LDD0781  [3]
 LDCM0465  CL72 HCT 116 C1003(1.39); C339(1.01); C535(1.01); C538(1.01)  LDD0782  [3]
 LDCM0466  CL73 HCT 116 C1003(1.11); C339(1.02); C535(0.88); C538(0.88)  LDD0783  [3]
 LDCM0467  CL74 HCT 116 C1003(1.06); C339(1.27); C535(0.91); C538(0.91)  LDD0784  [3]
 LDCM0469  CL76 HCT 116 C1003(1.10); C339(0.76); C563(1.04); C566(1.04)  LDD0786  [3]
 LDCM0470  CL77 HCT 116 C1003(1.14); C339(0.89); C563(0.89); C566(0.89)  LDD0787  [3]
 LDCM0471  CL78 HCT 116 C1003(1.15); C339(0.81); C563(0.85); C566(0.85)  LDD0788  [3]
 LDCM0472  CL79 HCT 116 C1003(1.17); C339(0.95); C563(0.76); C566(0.76)  LDD0789  [3]
 LDCM0473  CL8 HCT 116 C1003(1.05); C339(1.24); C535(0.62); C538(0.62)  LDD0790  [3]
 LDCM0474  CL80 HCT 116 C1003(1.39); C339(0.90); C563(0.93); C566(0.93)  LDD0791  [3]
 LDCM0475  CL81 HCT 116 C1003(1.26); C339(0.69); C563(0.81); C566(0.81)  LDD0792  [3]
 LDCM0476  CL82 HCT 116 C1003(1.21); C339(0.78); C563(0.86); C566(0.86)  LDD0793  [3]
 LDCM0477  CL83 HCT 116 C1003(1.10); C339(0.84); C563(0.82); C566(0.82)  LDD0794  [3]
 LDCM0478  CL84 HCT 116 C1003(1.70); C339(0.89); C563(0.79); C566(0.79)  LDD0795  [3]
 LDCM0479  CL85 HCT 116 C1003(1.37); C339(0.88); C563(0.74); C566(0.74)  LDD0796  [3]
 LDCM0480  CL86 HCT 116 C1003(1.31); C339(0.70); C563(0.98); C566(0.98)  LDD0797  [3]
 LDCM0481  CL87 HCT 116 C1003(1.65); C339(0.84); C563(0.93); C566(0.93)  LDD0798  [3]
 LDCM0482  CL88 HCT 116 C1003(1.20); C339(1.08); C563(0.93); C566(0.93)  LDD0799  [3]
 LDCM0483  CL89 HCT 116 C1003(1.27); C339(1.10); C563(0.99); C566(0.99)  LDD0800  [3]
 LDCM0484  CL9 HCT 116 C1003(0.93); C339(1.32); C535(0.82); C538(0.82)  LDD0801  [3]
 LDCM0485  CL90 HCT 116 C1003(1.10); C339(0.72); C563(0.82); C566(0.82)  LDD0802  [3]
 LDCM0486  CL91 HCT 116 C1003(1.42); C339(0.96); C563(1.07); C566(1.07)  LDD0803  [3]
 LDCM0487  CL92 HCT 116 C1003(1.11); C339(0.73); C563(0.78); C566(0.78)  LDD0804  [3]
 LDCM0488  CL93 HCT 116 C1003(1.28); C339(1.20); C563(0.99); C566(0.99)  LDD0805  [3]
 LDCM0489  CL94 HCT 116 C1003(1.51); C339(1.27); C563(0.71); C566(0.71)  LDD0806  [3]
 LDCM0490  CL95 HCT 116 C1003(1.16); C339(1.02); C563(0.71); C566(0.71)  LDD0807  [3]
 LDCM0491  CL96 HCT 116 C1003(1.57); C339(1.09); C563(1.08); C566(1.08)  LDD0808  [3]
 LDCM0492  CL97 HCT 116 C1003(1.60); C339(1.08); C563(1.04); C566(1.04)  LDD0809  [3]
 LDCM0493  CL98 HCT 116 C1003(1.30); C339(1.20); C563(0.96); C566(0.96)  LDD0810  [3]
 LDCM0494  CL99 HCT 116 C1003(1.34); C339(1.45); C563(0.88); C566(0.88)  LDD0811  [3]
 LDCM0634  CY-0357 Hep-G2 C91(0.73)  LDD2228  [8]
 LDCM0495  E2913 HEK-293T C339(1.15); C755(0.99); C1003(0.93); C91(0.98)  LDD1698  [10]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C339(2.19)  LDD1702  [11]
 LDCM0573  Fragment11 Ramos C91(0.04)  LDD2190  [12]
 LDCM0575  Fragment13 Ramos C91(0.65)  LDD2192  [12]
 LDCM0576  Fragment14 Ramos C91(3.45)  LDD2193  [12]
 LDCM0578  Fragment27 Ramos C91(0.67)  LDD2197  [12]
 LDCM0586  Fragment28 Ramos C91(0.34)  LDD2198  [12]
 LDCM0589  Fragment31 Ramos C91(0.43)  LDD2200  [12]
 LDCM0468  Fragment33 HCT 116 C1003(1.30); C339(1.16); C535(0.85); C538(0.85)  LDD0785  [3]
 LDCM0566  Fragment4 Ramos C91(1.32)  LDD2184  [12]
 LDCM0427  Fragment51 HCT 116 C1003(0.82); C339(1.06); C535(0.83); C538(0.83)  LDD0744  [3]
 LDCM0610  Fragment52 Ramos C91(1.28)  LDD2204  [12]
 LDCM0614  Fragment56 Ramos C91(0.53)  LDD2205  [12]
 LDCM0569  Fragment7 Ramos C91(1.27)  LDD2186  [12]
 LDCM0022  KB02 HCT 116 C672(3.90); C735(2.10); C738(2.10); C535(2.13)  LDD0080  [3]
 LDCM0023  KB03 HCT 116 C672(2.09); C735(1.87); C738(1.87); C535(2.58)  LDD0081  [3]
 LDCM0024  KB05 HCT 116 C672(2.73); C735(2.18); C738(2.18); C535(2.18)  LDD0082  [3]
 LDCM0131  RA190 MM1.R C91(0.93)  LDD0304  [13]
 LDCM0021  THZ1 HCT 116 C339(1.49); C707(1.17); C710(1.17); C563(1.36)  LDD2173  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Testis-specific Y-encoded-like protein 2 (TSPYL2) Nucleosome assembly protein (NAP) family Q9H2G4

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
3 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
4 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
5 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
6 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
7 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
8 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
9 Covalent Inhibition by a Natural Product-Inspired Latent Electrophile. J Am Chem Soc. 2023 May 24;145(20):11097-11109. doi: 10.1021/jacs.3c00598. Epub 2023 May 15.
10 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
11 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
12 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
13 Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190. Cell Chem Biol. 2020 Nov 19;27(11):1371-1382.e6. doi: 10.1016/j.chembiol.2020.08.007. Epub 2020 Aug 27.