Details of the Target

General Information of Target

Target ID LDTP06883
Target Name Fibronectin type III domain-containing protein 3B (FNDC3B)
Gene Name FNDC3B
Gene ID 64778
Synonyms
FAD104; NS5ABP37; Fibronectin type III domain-containing protein 3B; Factor for adipocyte differentiation 104; HCV NS5A-binding protein 37
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MYVTMMMTDQIPLELPPLLNGEVAMMPHLVNGDAAQQVILVQVNPGETFTIRAEDGTLQC
IQGPAEVPMMSPNGSIPPIHVPPGYISQVIEDSTGVRRVVVTPQSPECYPPSYPSAMSPT
HHLPPYLTHHPHFIHNSHTAYYPPVTGPGDMPPQFFPQHHLPHTIYGEQEIIPFYGMSTY
ITREDQYSKPPHKKLKDRQIDRQNRLNSPPSSIYKSSCTTVYNGYGKGHSGGSGGGGSGS
GPGIKKTERRARSSPKSNDSDLQEYELEVKRVQDILSGIEKPQVSNIQARAVVLSWAPPV
GLSCGPHSGLSFPYSYEVALSDKGRDGKYKIIYSGEELECNLKDLRPATDYHVRVYAMYN
SVKGSCSEPVSFTTHSCAPECPFPPKLAHRSKSSLTLQWKAPIDNGSKITNYLLEWDEGK
RNSGFRQCFFGSQKHCKLTKLCPAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSA
PRLVRAGITWVTLQWSKPEGCSPEEVITYTLEIQEDENDNLFHPKYTGEDLTCTVKNLKR
STQYKFRLTASNTEGKSCPSEVLVCTTSPDRPGPPTRPLVKGPVTSHGFSVKWDPPKDNG
GSEILKYLLEITDGNSEANQWEVAYSGSATEYTFTHLKPGTLYKLRACCISTGGHSQCSE
SLPVRTLSIAPGQCRPPRVLGRPKHKEVHLEWDVPASESGCEVSEYSVEMTEPEDVASEV
YHGPELECTVGNLLPGTVYRFRVRALNDGGYGPYSDVSEITTAAGPPGQCKAPCISCTPD
GCVLVGWESPDSSGADISEYRLEWGEDEESLELIYHGTDTRFEIRDLLPAAQYCCRLQAF
NQAGAGPYSELVLCQTPASAPDPVSTLCVLEEEPLDAYPDSPSACLVLNWEEPCNNGSEI
LAYTIDLGDTSITVGNTTMHVMKDLLPETTYRIRIQAINEIGAGPFSQFIKAKTRPLPPL
PPRLECAAAGPQSLKLKWGDSNSKTHAAEDIVYTLQLEDRNKRFISIYRGPSHTYKVQRL
TEFTCYSFRIQAASEAGEGPFSETYTFSTTKSVPPTIKAPRVTQLEGNSCEILWETVPSM
KGDPVNYILQVLVGRESEYKQVYKGEEATFQISGLQTNTDYRFRVCACRRCLDTSQELSG
AFSPSAAFVLQRSEVMLTGDMGSLDDPKMKSMMPTDEQFAAIIVLGFATLSILFAFILQY
FLMK
Target Bioclass
Enzyme
Family
FNDC3 family
Subcellular location
Membrane
Function May be a positive regulator of adipogenesis.
Uniprot ID
Q53EP0
Ensemble ID
ENST00000336824.8
HGNC ID
HGNC:24670

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
CCK81 SNV: p.L15P DBIA    Probe Info 
HCC1395 SNV: p.P927S DBIA    Probe Info 
HCT15 SNV: p.P583T DBIA    Probe Info 
HT3 SNV: p.H587Y DBIA    Probe Info 
IM95 Insertion: p.T1056HfsTer16 DBIA    Probe Info 
Ishikawa (Heraklio) 02 ER SNV: p.A291V DBIA    Probe Info 
MDST8 SNV: p.E892K DBIA    Probe Info 
NCIH1299 Insertion: p.W495FfsTer9 .
NCIH2286 SNV: p.Q476L DBIA    Probe Info 
P31FUJ Insertion: p.Y447VfsTer17 DBIA    Probe Info 
SNU478 SNV: p.H229R; p.A845S DBIA    Probe Info 
SUPT1 SNV: p.L784S .
SW756 SNV: p.E499Q DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 15 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
STPyne
 Probe Info  		K1016(1.19); K420(7.69); K536(5.26); K951(5.16)  LDD0277  [2]
BTD
 Probe Info  		C966(0.28)  LDD1700  [3]
Sulforaphane-probe2
 Probe Info  		1.60  LDD0160  [4]
AHL-Pu-1
 Probe Info  		C304(2.32); C1025(2.34)  LDD0171  [5]
DBIA
 Probe Info  		C558(1.45); C366(1.12); C377(1.12); C565(1.10)  LDD0078  [6]
IA-alkyne
 Probe Info  		C218(0.00); C442(0.00)  LDD0162  [7]
NAIA_4
 Probe Info  		N.A.  LDD2226  [8]
IPM
 Probe Info  		C1131(0.00); C533(0.00); C218(0.00); C1025(0.00)  LDD0147  [9]
TFBX
 Probe Info  		C835(0.00); C1131(0.00); C442(0.00); C218(0.00)  LDD0148  [9]
Phosphinate-6
 Probe Info  		C381(0.00); C442(0.00)  LDD0018  [10]
Acrolein
 Probe Info  		C533(0.00); C649(0.00); C658(0.00)  LDD0217  [11]
Methacrolein
 Probe Info  		C533(0.00); C966(0.00); C658(0.00)  LDD0218  [11]
W1
 Probe Info  		N.A.  LDD0236  [12]
NAIA_5
 Probe Info  		N.A.  LDD2223  [8]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C649(0.60)  LDD2142  [3]
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C649(1.05)  LDD2112  [3]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C674(1.13)  LDD2117  [3]
 LDCM0026  4SU-RNA+native RNA DM93 C304(2.32); C1025(2.34)  LDD0171  [5]
 LDCM0214  AC1 HCT 116 C428(1.14); C442(1.04); C558(1.55); C565(1.55)  LDD0531  [6]
 LDCM0215  AC10 HCT 116 C366(0.75); C1025(1.35); C218(1.06); C377(0.75)  LDD0532  [6]
 LDCM0216  AC100 HCT 116 C366(0.90); C218(0.95); C377(0.90); C381(0.69)  LDD0533  [6]
 LDCM0217  AC101 HCT 116 C366(1.01); C218(1.20); C377(1.01); C381(0.61)  LDD0534  [6]
 LDCM0218  AC102 HCT 116 C366(0.99); C218(0.98); C377(0.99); C381(0.71)  LDD0535  [6]
 LDCM0219  AC103 HCT 116 C366(1.15); C218(1.11); C377(1.15); C381(0.68)  LDD0536  [6]
 LDCM0220  AC104 HCT 116 C366(0.98); C218(0.99); C377(0.98); C381(0.82)  LDD0537  [6]
 LDCM0221  AC105 HCT 116 C366(0.94); C218(1.35); C377(0.94); C381(0.62)  LDD0538  [6]
 LDCM0222  AC106 HCT 116 C366(0.98); C218(1.27); C377(0.98); C381(0.60)  LDD0539  [6]
 LDCM0223  AC107 HCT 116 C366(0.91); C218(1.01); C377(0.91); C381(0.58)  LDD0540  [6]
 LDCM0224  AC108 HCT 116 C366(0.96); C218(1.09); C377(0.96); C381(0.54)  LDD0541  [6]
 LDCM0225  AC109 HCT 116 C366(0.90); C218(0.93); C377(0.90); C381(0.66)  LDD0542  [6]
 LDCM0226  AC11 HCT 116 C366(1.16); C1025(1.65); C218(1.21); C377(1.16)  LDD0543  [6]
 LDCM0227  AC110 HCT 116 C366(1.17); C218(1.32); C377(1.17); C381(0.78)  LDD0544  [6]
 LDCM0228  AC111 HCT 116 C366(1.06); C218(1.27); C377(1.06); C381(0.78)  LDD0545  [6]
 LDCM0229  AC112 HCT 116 C366(1.25); C218(1.22); C377(1.25); C381(0.65)  LDD0546  [6]
 LDCM0230  AC113 HCT 116 C366(0.95); C1025(0.97); C218(0.94); C377(0.95)  LDD0547  [6]
 LDCM0231  AC114 HCT 116 C366(0.92); C1025(0.89); C218(0.94); C377(0.92)  LDD0548  [6]
 LDCM0232  AC115 HCT 116 C366(0.99); C1025(0.95); C218(0.87); C377(0.99)  LDD0549  [6]
 LDCM0233  AC116 HCT 116 C366(0.96); C1025(0.98); C218(1.22); C377(0.96)  LDD0550  [6]
 LDCM0234  AC117 HCT 116 C366(0.95); C1025(1.07); C218(0.81); C377(0.95)  LDD0551  [6]
 LDCM0235  AC118 HCT 116 C366(0.90); C1025(1.00); C218(0.79); C377(0.90)  LDD0552  [6]
 LDCM0236  AC119 HCT 116 C366(0.98); C1025(0.82); C218(0.83); C377(0.98)  LDD0553  [6]
 LDCM0237  AC12 HCT 116 C366(0.85); C1025(0.93); C218(0.97); C377(0.85)  LDD0554  [6]
 LDCM0238  AC120 HCT 116 C366(1.17); C1025(0.90); C218(0.80); C377(1.17)  LDD0555  [6]
 LDCM0239  AC121 HCT 116 C366(0.88); C1025(1.02); C218(1.05); C377(0.88)  LDD0556  [6]
 LDCM0240  AC122 HCT 116 C366(0.94); C1025(1.18); C218(0.90); C377(0.94)  LDD0557  [6]
 LDCM0241  AC123 HCT 116 C366(0.97); C1025(0.92); C218(0.72); C377(0.97)  LDD0558  [6]
 LDCM0242  AC124 HCT 116 C366(1.08); C1025(0.94); C218(0.86); C377(1.08)  LDD0559  [6]
 LDCM0243  AC125 HCT 116 C366(0.89); C1025(0.88); C218(1.04); C377(0.89)  LDD0560  [6]
 LDCM0244  AC126 HCT 116 C366(0.86); C1025(0.98); C218(0.87); C377(0.86)  LDD0561  [6]
 LDCM0245  AC127 HCT 116 C366(0.87); C1025(0.99); C218(0.90); C377(0.87)  LDD0562  [6]
 LDCM0246  AC128 HCT 116 C366(1.66); C218(0.73); C377(1.66); C558(1.57)  LDD0563  [6]
 LDCM0247  AC129 HCT 116 C366(1.02); C218(0.70); C377(1.02); C558(1.18)  LDD0564  [6]
 LDCM0249  AC130 HCT 116 C366(1.35); C218(0.62); C377(1.35); C558(1.07)  LDD0566  [6]
 LDCM0250  AC131 HCT 116 C366(1.27); C218(0.69); C377(1.27); C558(1.22)  LDD0567  [6]
 LDCM0251  AC132 HCT 116 C366(0.98); C218(0.70); C377(0.98); C558(0.94)  LDD0568  [6]
 LDCM0252  AC133 HCT 116 C366(1.22); C218(0.72); C377(1.22); C558(1.18)  LDD0569  [6]
 LDCM0253  AC134 HCT 116 C366(1.38); C218(0.78); C377(1.38); C558(1.04)  LDD0570  [6]
 LDCM0254  AC135 HCT 116 C366(1.48); C218(0.69); C377(1.48); C558(0.97)  LDD0571  [6]
 LDCM0255  AC136 HCT 116 C366(1.29); C218(0.72); C377(1.29); C558(1.03)  LDD0572  [6]
 LDCM0256  AC137 HCT 116 C366(1.26); C218(0.76); C377(1.26); C558(0.98)  LDD0573  [6]
 LDCM0257  AC138 HCT 116 C366(1.57); C218(0.92); C377(1.57); C558(0.88)  LDD0574  [6]
 LDCM0258  AC139 HCT 116 C366(1.07); C218(0.74); C377(1.07); C558(1.10)  LDD0575  [6]
 LDCM0259  AC14 HCT 116 C366(1.22); C1025(1.13); C218(0.84); C377(1.22)  LDD0576  [6]
 LDCM0260  AC140 HCT 116 C366(1.08); C218(0.98); C377(1.08); C558(1.00)  LDD0577  [6]
 LDCM0261  AC141 HCT 116 C366(1.31); C218(0.93); C377(1.31); C558(0.97)  LDD0578  [6]
 LDCM0262  AC142 HCT 116 C366(1.12); C218(0.70); C377(1.12); C558(1.11)  LDD0579  [6]
 LDCM0263  AC143 HCT 116 C366(1.00); C218(0.89); C377(1.00); C381(0.97)  LDD0580  [6]
 LDCM0264  AC144 HCT 116 C558(0.67); C565(0.67); C218(0.78); C377(1.03)  LDD0581  [6]
 LDCM0265  AC145 HCT 116 C558(0.68); C565(0.68); C218(0.74); C381(0.92)  LDD0582  [6]
 LDCM0266  AC146 HCT 116 C218(0.88); C558(0.92); C565(0.92); C377(1.07)  LDD0583  [6]
 LDCM0267  AC147 HCT 116 C218(0.82); C558(0.85); C565(0.85); C366(0.98)  LDD0584  [6]
 LDCM0268  AC148 HCT 116 C218(0.75); C834(0.95); C835(0.95); C558(1.19)  LDD0585  [6]
 LDCM0269  AC149 HCT 116 C834(0.89); C835(0.89); C558(0.91); C565(0.91)  LDD0586  [6]
 LDCM0270  AC15 HCT 116 C834(0.80); C835(0.80); C366(0.99); C377(0.99)  LDD0587  [6]
 LDCM0271  AC150 HCT 116 C558(0.69); C565(0.69); C218(0.76); C834(0.86)  LDD0588  [6]
 LDCM0272  AC151 HCT 116 C558(0.64); C565(0.64); C218(0.79); C834(0.93)  LDD0589  [6]
 LDCM0273  AC152 HCT 116 C218(0.74); C834(1.03); C835(1.03); C377(1.17)  LDD0590  [6]
 LDCM0274  AC153 HCT 116 C218(0.73); C834(0.82); C835(0.82); C381(1.17)  LDD0591  [6]
 LDCM0621  AC154 HCT 116 C366(1.12); C218(0.59); C377(1.12); C381(1.19)  LDD2158  [6]
 LDCM0622  AC155 HCT 116 C366(1.03); C218(0.74); C377(1.07); C381(1.04)  LDD2159  [6]
 LDCM0623  AC156 HCT 116 C366(1.13); C218(0.83); C377(1.12); C381(1.12)  LDD2160  [6]
 LDCM0624  AC157 HCT 116 C366(1.34); C218(0.64); C377(1.35); C381(1.36)  LDD2161  [6]
 LDCM0276  AC17 HCT 116 C377(0.74); C381(0.74); C442(0.83); C558(0.99)  LDD0593  [6]
 LDCM0277  AC18 HCT 116 C442(0.83); C558(1.04); C565(1.04); C377(1.23)  LDD0594  [6]
 LDCM0278  AC19 HCT 116 C377(0.82); C381(0.82); C442(0.89); C558(0.95)  LDD0595  [6]
 LDCM0279  AC2 HCT 116 C834(0.64); C835(0.64); C442(1.02); C428(1.06)  LDD0596  [6]
 LDCM0280  AC20 HCT 116 C377(0.77); C381(0.77); C442(0.90); C558(0.96)  LDD0597  [6]
 LDCM0281  AC21 HCT 116 C442(0.81); C377(1.05); C381(1.05); C558(1.11)  LDD0598  [6]
 LDCM0282  AC22 HCT 116 C377(0.83); C381(0.83); C442(0.85); C558(0.90)  LDD0599  [6]
 LDCM0283  AC23 HCT 116 C558(0.84); C565(0.84); C442(0.92); C377(0.93)  LDD0600  [6]
 LDCM0284  AC24 HCT 116 C442(0.84); C558(0.95); C565(0.95); C218(1.16)  LDD0601  [6]
 LDCM0285  AC25 HCT 116 C834(0.69); C835(0.69); C366(0.73); C377(0.80)  LDD0602  [6]
 LDCM0286  AC26 HCT 116 C834(0.66); C835(0.66); C381(0.77); C558(0.77)  LDD0603  [6]
 LDCM0287  AC27 HCT 116 C834(0.59); C835(0.59); C558(0.80); C565(0.80)  LDD0604  [6]
 LDCM0288  AC28 HCT 116 C834(0.64); C835(0.64); C442(0.74); C381(0.77)  LDD0605  [6]
 LDCM0289  AC29 HCT 116 C834(0.62); C835(0.62); C558(0.67); C565(0.67)  LDD0606  [6]
 LDCM0290  AC3 HCT 116 C834(0.71); C835(0.71); C428(1.08); C442(1.11)  LDD0607  [6]
 LDCM0291  AC30 HCT 116 C834(0.61); C835(0.61); C381(0.79); C558(0.80)  LDD0608  [6]
 LDCM0292  AC31 HCT 116 C834(0.68); C835(0.68); C381(0.85); C558(0.91)  LDD0609  [6]
 LDCM0293  AC32 HCT 116 C834(0.60); C835(0.60); C381(0.79); C558(0.80)  LDD0610  [6]
 LDCM0294  AC33 HCT 116 C834(0.69); C835(0.69); C442(0.96); C381(0.99)  LDD0611  [6]
 LDCM0295  AC34 HCT 116 C834(0.88); C835(0.88); C558(0.95); C565(0.95)  LDD0612  [6]
 LDCM0296  AC35 HCT 116 C366(0.63); C377(0.63); C381(0.67); C218(1.09)  LDD0613  [6]
 LDCM0297  AC36 HCT 116 C366(0.71); C377(0.71); C381(0.77); C834(0.92)  LDD0614  [6]
 LDCM0298  AC37 HCT 116 C366(0.80); C377(0.80); C558(0.82); C565(0.82)  LDD0615  [6]
 LDCM0299  AC38 HCT 116 C366(0.81); C377(0.81); C834(0.82); C835(0.82)  LDD0616  [6]
 LDCM0300  AC39 HCT 116 C366(0.67); C377(0.67); C381(0.69); C442(0.92)  LDD0617  [6]
 LDCM0301  AC4 HCT 116 C834(0.63); C835(0.63); C442(0.83); C428(1.30)  LDD0618  [6]
 LDCM0302  AC40 HCT 116 C366(0.88); C377(0.88); C381(0.95); C558(1.06)  LDD0619  [6]
 LDCM0303  AC41 HCT 116 C558(0.94); C565(0.94); C366(1.10); C377(1.10)  LDD0620  [6]
 LDCM0304  AC42 HCT 116 C558(0.90); C565(0.90); C834(0.98); C835(0.98)  LDD0621  [6]
 LDCM0305  AC43 HCT 116 C834(0.79); C835(0.79); C558(0.93); C565(0.93)  LDD0622  [6]
 LDCM0306  AC44 HCT 116 C558(0.84); C565(0.84); C218(1.07); C442(1.14)  LDD0623  [6]
 LDCM0307  AC45 HCT 116 C558(1.06); C565(1.06); C442(1.17); C366(1.20)  LDD0624  [6]
 LDCM0308  AC46 HCT 116 C558(0.79); C565(0.79); C218(1.02)  LDD0625  [6]
 LDCM0309  AC47 HCT 116 C558(0.82); C565(0.82); C218(0.99)  LDD0626  [6]
 LDCM0310  AC48 HCT 116 C558(0.85); C565(0.85); C218(0.96)  LDD0627  [6]
 LDCM0311  AC49 HCT 116 C558(0.72); C565(0.72); C218(1.40)  LDD0628  [6]
 LDCM0312  AC5 HCT 116 C834(0.54); C835(0.54); C442(1.03); C428(1.11)  LDD0629  [6]
 LDCM0313  AC50 HCT 116 C558(0.78); C565(0.78); C218(1.28)  LDD0630  [6]
 LDCM0314  AC51 HCT 116 C558(0.72); C565(0.72); C218(0.88)  LDD0631  [6]
 LDCM0315  AC52 HCT 116 C558(0.71); C565(0.71); C218(1.04)  LDD0632  [6]
 LDCM0316  AC53 HCT 116 C558(0.74); C565(0.74); C218(1.36)  LDD0633  [6]
 LDCM0317  AC54 HCT 116 C558(0.75); C565(0.75); C218(1.26)  LDD0634  [6]
 LDCM0318  AC55 HCT 116 C558(0.96); C565(0.96); C218(1.22)  LDD0635  [6]
 LDCM0319  AC56 HCT 116 C558(0.97); C565(0.97); C218(1.76)  LDD0636  [6]
 LDCM0320  AC57 HCT 116 C366(0.86); C377(0.86); C834(0.98); C835(0.98)  LDD0637  [6]
 LDCM0321  AC58 HCT 116 C381(0.97); C834(0.99); C835(0.99); C366(1.05)  LDD0638  [6]
 LDCM0322  AC59 HCT 116 C834(0.93); C835(0.93); C366(1.11); C377(1.11)  LDD0639  [6]
 LDCM0323  AC6 HCT 116 C834(0.87); C835(0.87); C442(1.04); C218(1.07)  LDD0640  [6]
 LDCM0324  AC60 HCT 116 C366(1.01); C377(1.01); C834(1.07); C835(1.07)  LDD0641  [6]
 LDCM0325  AC61 HCT 116 C834(0.84); C835(0.84); C366(0.90); C377(0.90)  LDD0642  [6]
 LDCM0326  AC62 HCT 116 C366(0.88); C377(0.88); C834(0.93); C835(0.93)  LDD0643  [6]
 LDCM0327  AC63 HCT 116 C366(0.87); C377(0.87); C381(0.94); C834(0.99)  LDD0644  [6]
 LDCM0328  AC64 HCT 116 C366(0.81); C377(0.81); C381(0.89); C442(1.07)  LDD0645  [6]
 LDCM0329  AC65 HCT 116 C381(0.76); C366(0.85); C377(0.85); C834(0.91)  LDD0646  [6]
 LDCM0330  AC66 HCT 116 C834(0.88); C835(0.88); C381(0.94); C366(0.94)  LDD0647  [6]
 LDCM0331  AC67 HCT 116 C381(0.82); C366(0.91); C377(0.91); C834(1.02)  LDD0648  [6]
 LDCM0332  AC68 HCT 116 C442(0.76); C558(0.83); C565(0.83); C834(0.96)  LDD0649  [6]
 LDCM0333  AC69 HCT 116 C442(0.82); C558(0.88); C565(0.88); C366(1.03)  LDD0650  [6]
 LDCM0334  AC7 HCT 116 C834(0.86); C835(0.86); C442(0.94); C366(0.97)  LDD0651  [6]
 LDCM0335  AC70 HCT 116 C442(0.74); C366(0.76); C377(0.78); C381(0.89)  LDD0652  [6]
 LDCM0336  AC71 HCT 116 C442(0.72); C558(0.93); C565(0.93); C366(0.98)  LDD0653  [6]
 LDCM0337  AC72 HCT 116 C442(0.71); C366(0.82); C558(0.83); C565(0.83)  LDD0654  [6]
 LDCM0338  AC73 HCT 116 C442(0.92); C366(0.93); C377(0.97); C381(0.99)  LDD0655  [6]
 LDCM0339  AC74 HCT 116 C442(0.74); C366(0.99); C377(1.02); C381(1.10)  LDD0656  [6]
 LDCM0340  AC75 HCT 116 C366(0.81); C377(0.82); C442(0.94); C381(1.02)  LDD0657  [6]
 LDCM0341  AC76 HCT 116 C558(0.73); C565(0.73); C366(0.78); C377(0.80)  LDD0658  [6]
 LDCM0342  AC77 HCT 116 C558(0.65); C565(0.65); C442(0.75); C834(1.07)  LDD0659  [6]
 LDCM0343  AC78 HCT 116 C442(0.71); C558(0.83); C565(0.83); C834(0.97)  LDD0660  [6]
 LDCM0344  AC79 HCT 116 C442(0.86); C834(0.93); C835(0.93); C366(0.94)  LDD0661  [6]
 LDCM0345  AC8 HCT 116 C834(0.77); C835(0.77); C558(0.91); C565(0.91)  LDD0662  [6]
 LDCM0346  AC80 HCT 116 C442(0.82); C558(0.93); C565(0.93); C366(0.99)  LDD0663  [6]
 LDCM0347  AC81 HCT 116 C442(0.75); C366(0.91); C218(0.93); C377(1.00)  LDD0664  [6]
 LDCM0348  AC82 HCT 116 C442(0.78); C366(0.83); C377(0.87); C381(0.99)  LDD0665  [6]
 LDCM0349  AC83 HCT 116 C834(0.53); C835(0.53); C558(0.98); C565(0.98)  LDD0666  [6]
 LDCM0350  AC84 HCT 116 C834(0.53); C835(0.53); C366(1.01); C381(1.01)  LDD0667  [6]
 LDCM0351  AC85 HCT 116 C834(0.50); C835(0.50); C558(0.76); C565(0.76)  LDD0668  [6]
 LDCM0352  AC86 HCT 116 C834(0.39); C835(0.39); C558(0.74); C565(0.74)  LDD0669  [6]
 LDCM0353  AC87 HCT 116 C834(0.45); C835(0.45); C218(0.83); C558(0.89)  LDD0670  [6]
 LDCM0354  AC88 HCT 116 C834(0.43); C835(0.43); C218(0.80); C381(0.85)  LDD0671  [6]
 LDCM0355  AC89 HCT 116 C834(0.57); C835(0.57); C218(0.80); C381(0.92)  LDD0672  [6]
 LDCM0357  AC90 HCT 116 C834(0.36); C835(0.36); C381(0.66); C366(0.67)  LDD0674  [6]
 LDCM0358  AC91 HCT 116 C834(0.66); C835(0.66); C377(0.89); C366(0.94)  LDD0675  [6]
 LDCM0359  AC92 HCT 116 C834(0.50); C835(0.50); C381(0.86); C366(0.87)  LDD0676  [6]
 LDCM0360  AC93 HCT 116 C834(0.50); C835(0.50); C558(0.79); C565(0.79)  LDD0677  [6]
 LDCM0361  AC94 HCT 116 C834(0.71); C835(0.71); C558(0.78); C565(0.78)  LDD0678  [6]
 LDCM0362  AC95 HCT 116 C834(0.44); C835(0.44); C381(0.93); C218(1.02)  LDD0679  [6]
 LDCM0363  AC96 HCT 116 C558(0.80); C565(0.80); C381(0.91); C834(0.93)  LDD0680  [6]
 LDCM0364  AC97 HCT 116 C834(0.42); C835(0.42); C558(0.75); C565(0.75)  LDD0681  [6]
 LDCM0365  AC98 HCT 116 C834(0.67); C835(0.67); C558(0.73); C565(0.73)  LDD0682  [6]
 LDCM0366  AC99 HCT 116 C558(0.57); C565(0.57); C381(0.63); C834(0.69)  LDD0683  [6]
 LDCM0248  AKOS034007472 HCT 116 C366(0.86); C1025(1.12); C218(0.84); C377(0.86)  LDD0565  [6]
 LDCM0356  AKOS034007680 HCT 116 C834(0.79); C835(0.79); C366(0.87); C377(0.87)  LDD0673  [6]
 LDCM0275  AKOS034007705 HCT 116 C834(0.88); C835(0.88); C366(1.09); C377(1.09)  LDD0592  [6]
 LDCM0020  ARS-1620 HCC44 C558(1.45); C366(1.12); C377(1.12); C565(1.10)  LDD0078  [6]
 LDCM0108  Chloroacetamide HeLa C533(0.00); C1070(0.00); H229(0.00); C649(0.00)  LDD0222  [11]
 LDCM0367  CL1 HCT 116 C218(0.69); C558(0.91); C565(0.91); C834(1.01)  LDD0684  [6]
 LDCM0368  CL10 HCT 116 C377(0.92); C381(0.99); C366(0.99); C834(1.11)  LDD0685  [6]
 LDCM0369  CL100 HCT 116 C834(0.65); C835(0.65); C442(0.93); C428(1.04)  LDD0686  [6]
 LDCM0370  CL101 HCT 116 C834(0.83); C835(0.83); C1025(0.89); C218(1.10)  LDD0687  [6]
 LDCM0371  CL102 HCT 116 C834(0.82); C835(0.82); C218(0.86); C558(1.04)  LDD0688  [6]
 LDCM0372  CL103 HCT 116 C834(0.88); C835(0.88); C218(0.97); C366(0.98)  LDD0689  [6]
 LDCM0373  CL104 HCT 116 C218(0.94); C834(1.01); C835(1.01); C558(1.05)  LDD0690  [6]
 LDCM0374  CL105 HCT 116 C442(0.84); C377(1.00); C381(1.00); C558(1.04)  LDD0691  [6]
 LDCM0375  CL106 HCT 116 C442(0.73); C377(1.09); C381(1.09); C558(1.15)  LDD0692  [6]
 LDCM0376  CL107 HCT 116 C558(0.91); C565(0.91); C442(0.91); C377(0.99)  LDD0693  [6]
 LDCM0377  CL108 HCT 116 C442(0.86); C377(0.91); C381(0.91); C558(1.00)  LDD0694  [6]
 LDCM0378  CL109 HCT 116 C558(0.97); C565(0.97); C442(0.98); C377(1.17)  LDD0695  [6]
 LDCM0379  CL11 HCT 116 C558(0.99); C565(0.99); C834(0.99); C835(0.99)  LDD0696  [6]
 LDCM0380  CL110 HCT 116 C442(0.79); C558(1.07); C565(1.07); C377(1.08)  LDD0697  [6]
 LDCM0381  CL111 HCT 116 C442(0.69); C558(1.05); C565(1.05); C218(1.30)  LDD0698  [6]
 LDCM0382  CL112 HCT 116 C834(0.62); C835(0.62); C442(1.04); C218(1.11)  LDD0699  [6]
 LDCM0383  CL113 HCT 116 C834(0.59); C835(0.59); C381(0.83); C558(0.86)  LDD0700  [6]
 LDCM0384  CL114 HCT 116 C834(0.55); C835(0.55); C558(0.72); C565(0.72)  LDD0701  [6]
 LDCM0385  CL115 HCT 116 C834(0.69); C835(0.69); C558(0.80); C565(0.80)  LDD0702  [6]
 LDCM0386  CL116 HCT 116 C834(0.79); C835(0.79); C442(0.96); C558(1.01)  LDD0703  [6]
 LDCM0387  CL117 HCT 116 C834(0.73); C835(0.73); C558(1.09); C565(1.09)  LDD0704  [6]
 LDCM0388  CL118 HCT 116 C366(0.82); C377(0.82); C218(0.93); C381(1.00)  LDD0705  [6]
 LDCM0389  CL119 HCT 116 C366(0.79); C377(0.79); C381(0.91); C834(0.91)  LDD0706  [6]
 LDCM0390  CL12 HCT 116 C377(0.91); C366(0.97); C834(1.04); C835(1.04)  LDD0707  [6]
 LDCM0391  CL120 HCT 116 C558(0.92); C565(0.92); C366(0.93); C377(0.93)  LDD0708  [6]
 LDCM0392  CL121 HCT 116 C218(0.84); C558(1.59); C565(1.59)  LDD0709  [6]
 LDCM0393  CL122 HCT 116 C558(0.79); C565(0.79); C218(1.09)  LDD0710  [6]
 LDCM0394  CL123 HCT 116 C558(0.88); C565(0.88); C218(1.29)  LDD0711  [6]
 LDCM0395  CL124 HCT 116 C558(0.73); C565(0.73); C218(1.34)  LDD0712  [6]
 LDCM0396  CL125 HCT 116 C381(0.83); C834(0.86); C835(0.86); C442(0.86)  LDD0713  [6]
 LDCM0397  CL126 HCT 116 C834(0.98); C835(0.98); C366(1.06); C377(1.06)  LDD0714  [6]
 LDCM0398  CL127 HCT 116 C381(0.84); C834(0.89); C835(0.89); C366(0.91)  LDD0715  [6]
 LDCM0399  CL128 HCT 116 C381(0.86); C366(0.89); C377(0.89); C834(0.97)  LDD0716  [6]
 LDCM0400  CL13 HCT 116 C377(0.85); C381(0.86); C366(0.86); C834(1.15)  LDD0717  [6]
 LDCM0401  CL14 HCT 116 C558(0.81); C565(0.81); C377(0.98); C366(0.99)  LDD0718  [6]
 LDCM0402  CL15 HCT 116 C381(0.75); C366(0.88); C377(0.88); C218(0.90)  LDD0719  [6]
 LDCM0403  CL16 HCT 116 C218(0.83); C834(0.98); C835(0.98); C428(1.06)  LDD0720  [6]
 LDCM0404  CL17 HCT 116 C442(0.62); C428(0.84); C558(0.90); C565(0.90)  LDD0721  [6]
 LDCM0405  CL18 HCT 116 C442(0.64); C381(0.80); C1025(0.83); C366(0.86)  LDD0722  [6]
 LDCM0406  CL19 HCT 116 C442(0.72); C218(0.75); C428(0.89); C381(0.91)  LDD0723  [6]
 LDCM0407  CL2 HCT 116 C558(0.69); C565(0.69); C218(0.81); C377(0.91)  LDD0724  [6]
 LDCM0408  CL20 HCT 116 C381(0.92); C428(0.93); C558(0.98); C565(0.98)  LDD0725  [6]
 LDCM0409  CL21 HCT 116 C442(0.66); C1025(0.96); C834(1.00); C835(1.00)  LDD0726  [6]
 LDCM0410  CL22 HCT 116 C1025(0.88); C428(1.08); C381(1.08); C558(1.17)  LDD0727  [6]
 LDCM0411  CL23 HCT 116 C442(0.73); C428(0.89); C558(0.99); C565(0.99)  LDD0728  [6]
 LDCM0412  CL24 HCT 116 C442(0.89); C1025(0.95); C218(0.96); C558(1.01)  LDD0729  [6]
 LDCM0413  CL25 HCT 116 C366(0.85); C1025(0.94); C218(1.09); C377(0.85)  LDD0730  [6]
 LDCM0414  CL26 HCT 116 C366(1.03); C1025(0.96); C218(0.84); C377(1.03)  LDD0731  [6]
 LDCM0415  CL27 HCT 116 C366(1.08); C1025(0.96); C218(0.85); C377(1.08)  LDD0732  [6]
 LDCM0416  CL28 HCT 116 C366(1.11); C1025(0.81); C218(0.82); C377(1.11)  LDD0733  [6]
 LDCM0417  CL29 HCT 116 C366(1.20); C1025(1.02); C218(0.98); C377(1.20)  LDD0734  [6]
 LDCM0418  CL3 HCT 116 C366(0.99); C218(0.99); C377(1.01); C381(1.08)  LDD0735  [6]
 LDCM0419  CL30 HCT 116 C366(1.09); C1025(1.12); C218(0.89); C377(1.09)  LDD0736  [6]
 LDCM0420  CL31 HCT 116 C366(1.06); C1025(0.86); C218(1.13); C377(1.06)  LDD0737  [6]
 LDCM0421  CL32 HCT 116 C218(0.89); C428(1.75); C442(0.90); C558(1.20)  LDD0738  [6]
 LDCM0422  CL33 HCT 116 C218(1.11); C428(1.40); C442(1.04); C558(1.15)  LDD0739  [6]
 LDCM0423  CL34 HCT 116 C218(1.19); C428(1.37); C442(0.90); C558(0.93)  LDD0740  [6]
 LDCM0424  CL35 HCT 116 C218(1.21); C428(1.15); C442(0.98); C558(0.91)  LDD0741  [6]
 LDCM0425  CL36 HCT 116 C218(1.22); C428(1.26); C442(1.07); C558(0.97)  LDD0742  [6]
 LDCM0426  CL37 HCT 116 C218(1.54); C428(1.09); C442(1.05); C558(1.18)  LDD0743  [6]
 LDCM0428  CL39 HCT 116 C218(1.35); C428(1.13); C442(0.88); C558(0.96)  LDD0745  [6]
 LDCM0429  CL4 HCT 116 C366(1.12); C218(0.83); C377(1.09); C381(1.25)  LDD0746  [6]
 LDCM0430  CL40 HCT 116 C218(1.47); C428(1.08); C442(0.99); C558(0.85)  LDD0747  [6]
 LDCM0431  CL41 HCT 116 C218(1.44); C428(1.36); C442(1.12); C558(1.14)  LDD0748  [6]
 LDCM0432  CL42 HCT 116 C218(1.42); C428(1.40); C442(1.00); C558(1.35)  LDD0749  [6]
 LDCM0433  CL43 HCT 116 C218(1.47); C428(1.33); C442(0.91); C558(1.07)  LDD0750  [6]
 LDCM0434  CL44 HCT 116 C218(1.37); C428(1.29); C442(0.90); C558(1.36)  LDD0751  [6]
 LDCM0435  CL45 HCT 116 C218(1.12); C428(1.28); C442(0.92); C558(1.10)  LDD0752  [6]
 LDCM0436  CL46 HCT 116 C366(0.88); C377(0.88); C381(0.89); C428(0.81)  LDD0753  [6]
 LDCM0437  CL47 HCT 116 C366(1.07); C377(1.07); C381(0.97); C428(0.64)  LDD0754  [6]
 LDCM0438  CL48 HCT 116 C366(0.95); C377(0.95); C381(0.89); C428(0.74)  LDD0755  [6]
 LDCM0439  CL49 HCT 116 C366(0.97); C377(0.97); C381(1.02); C428(0.83)  LDD0756  [6]
 LDCM0440  CL5 HCT 116 C366(0.90); C218(0.97); C377(0.91); C381(0.94)  LDD0757  [6]
 LDCM0441  CL50 HCT 116 C366(1.18); C377(1.18); C381(1.19); C428(0.81)  LDD0758  [6]
 LDCM0442  CL51 HCT 116 C366(1.02); C377(1.02); C381(1.02); C428(0.84)  LDD0759  [6]
 LDCM0443  CL52 HCT 116 C366(1.19); C377(1.19); C381(0.88); C428(0.80)  LDD0760  [6]
 LDCM0444  CL53 HCT 116 C366(1.92); C377(1.92); C381(1.35); C428(1.21)  LDD0761  [6]
 LDCM0445  CL54 HCT 116 C366(0.88); C377(0.88); C381(0.76); C428(0.70)  LDD0762  [6]
 LDCM0446  CL55 HCT 116 C366(1.00); C377(1.00); C381(0.97); C428(0.75)  LDD0763  [6]
 LDCM0447  CL56 HCT 116 C366(0.98); C377(0.98); C381(0.74); C428(0.72)  LDD0764  [6]
 LDCM0448  CL57 HCT 116 C366(1.11); C377(1.11); C381(1.12); C428(0.79)  LDD0765  [6]
 LDCM0449  CL58 HCT 116 C366(1.14); C377(1.14); C381(1.30); C428(1.15)  LDD0766  [6]
 LDCM0450  CL59 HCT 116 C366(1.10); C377(1.10); C381(1.27); C428(0.89)  LDD0767  [6]
 LDCM0451  CL6 HCT 116 C366(0.94); C218(1.11); C377(0.97); C381(0.88)  LDD0768  [6]
 LDCM0452  CL60 HCT 116 C366(1.02); C377(1.02); C381(1.14); C428(1.16)  LDD0769  [6]
 LDCM0453  CL61 HCT 116 C366(0.69); C1025(1.08); C377(0.93); C381(1.17)  LDD0770  [6]
 LDCM0454  CL62 HCT 116 C366(0.63); C1025(0.97); C377(0.84); C381(1.05)  LDD0771  [6]
 LDCM0455  CL63 HCT 116 C366(0.96); C1025(1.00); C377(1.19); C381(1.42)  LDD0772  [6]
 LDCM0456  CL64 HCT 116 C366(0.69); C1025(1.02); C377(1.07); C381(1.46)  LDD0773  [6]
 LDCM0457  CL65 HCT 116 C366(0.67); C1025(0.91); C377(0.91); C381(1.15)  LDD0774  [6]
 LDCM0458  CL66 HCT 116 C366(0.62); C1025(0.98); C377(0.91); C381(1.21)  LDD0775  [6]
 LDCM0459  CL67 HCT 116 C366(0.71); C1025(0.86); C377(1.00); C381(1.29)  LDD0776  [6]
 LDCM0460  CL68 HCT 116 C366(1.13); C1025(1.05); C377(1.13); C381(1.14)  LDD0777  [6]
 LDCM0461  CL69 HCT 116 C366(0.77); C1025(1.09); C377(1.00); C381(1.24)  LDD0778  [6]
 LDCM0462  CL7 HCT 116 C366(0.68); C218(1.02); C377(0.66); C381(0.66)  LDD0779  [6]
 LDCM0463  CL70 HCT 116 C366(0.93); C1025(1.05); C377(1.05); C381(1.16)  LDD0780  [6]
 LDCM0464  CL71 HCT 116 C366(1.01); C1025(1.06); C377(1.38); C381(1.75)  LDD0781  [6]
 LDCM0465  CL72 HCT 116 C366(1.07); C1025(1.08); C377(1.05); C381(1.04)  LDD0782  [6]
 LDCM0466  CL73 HCT 116 C366(0.88); C1025(1.07); C377(1.06); C381(1.23)  LDD0783  [6]
 LDCM0467  CL74 HCT 116 C366(0.78); C1025(0.96); C377(1.21); C381(1.64)  LDD0784  [6]
 LDCM0469  CL76 HCT 116 C366(1.48); C1025(1.53); C218(0.97); C377(1.48)  LDD0786  [6]
 LDCM0470  CL77 HCT 116 C366(2.16); C1025(0.70); C218(0.80); C377(2.16)  LDD0787  [6]
 LDCM0471  CL78 HCT 116 C366(1.23); C1025(0.59); C218(0.87); C377(1.23)  LDD0788  [6]
 LDCM0472  CL79 HCT 116 C366(1.51); C1025(1.11); C218(0.93); C377(1.51)  LDD0789  [6]
 LDCM0473  CL8 HCT 116 C366(1.11); C218(1.43); C377(1.12); C381(0.99)  LDD0790  [6]
 LDCM0474  CL80 HCT 116 C366(1.17); C1025(0.67); C218(0.82); C377(1.17)  LDD0791  [6]
 LDCM0475  CL81 HCT 116 C366(0.98); C1025(0.56); C218(0.78); C377(0.98)  LDD0792  [6]
 LDCM0476  CL82 HCT 116 C366(1.40); C1025(0.46); C218(0.72); C377(1.40)  LDD0793  [6]
 LDCM0477  CL83 HCT 116 C366(2.67); C1025(0.88); C218(0.83); C377(2.67)  LDD0794  [6]
 LDCM0478  CL84 HCT 116 C366(1.36); C1025(1.26); C218(1.08); C377(1.36)  LDD0795  [6]
 LDCM0479  CL85 HCT 116 C366(1.62); C1025(1.10); C218(0.94); C377(1.62)  LDD0796  [6]
 LDCM0480  CL86 HCT 116 C366(1.50); C1025(0.59); C218(0.82); C377(1.50)  LDD0797  [6]
 LDCM0481  CL87 HCT 116 C366(1.44); C1025(0.68); C218(0.80); C377(1.44)  LDD0798  [6]
 LDCM0482  CL88 HCT 116 C366(1.85); C1025(0.95); C218(0.85); C377(1.85)  LDD0799  [6]
 LDCM0483  CL89 HCT 116 C366(1.36); C1025(1.25); C218(0.89); C377(1.36)  LDD0800  [6]
 LDCM0484  CL9 HCT 116 C366(0.93); C218(3.01); C377(0.92); C381(0.82)  LDD0801  [6]
 LDCM0485  CL90 HCT 116 C366(1.63); C1025(0.80); C218(0.87); C377(1.63)  LDD0802  [6]
 LDCM0486  CL91 HCT 116 C428(1.07); C442(0.93); C558(1.23); C565(1.23)  LDD0803  [6]
 LDCM0487  CL92 HCT 116 C428(1.18); C442(1.10); C558(1.02); C565(1.02)  LDD0804  [6]
 LDCM0488  CL93 HCT 116 C428(1.30); C442(1.26); C558(1.13); C565(1.13)  LDD0805  [6]
 LDCM0489  CL94 HCT 116 C428(0.98); C442(1.15); C558(1.30); C565(1.30)  LDD0806  [6]
 LDCM0490  CL95 HCT 116 C428(1.19); C442(1.08); C558(1.26); C565(1.26)  LDD0807  [6]
 LDCM0491  CL96 HCT 116 C428(1.08); C442(1.07); C558(1.33); C565(1.33)  LDD0808  [6]
 LDCM0492  CL97 HCT 116 C428(1.13); C442(1.28); C558(1.15); C565(1.15)  LDD0809  [6]
 LDCM0493  CL98 HCT 116 C428(1.15); C442(0.98); C558(1.14); C565(1.14)  LDD0810  [6]
 LDCM0494  CL99 HCT 116 C428(1.13); C442(0.89); C558(1.25); C565(1.25)  LDD0811  [6]
 LDCM0495  E2913 HEK-293T C1131(1.20); C442(1.10); C674(1.15); C558(0.96)  LDD1698  [13]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C218(2.05); C966(1.99); C428(1.96); C674(1.62)  LDD1702  [3]
 LDCM0468  Fragment33 HCT 116 C366(0.85); C1025(1.02); C377(1.00); C381(1.15)  LDD0785  [6]
 LDCM0427  Fragment51 HCT 116 C218(2.37); C428(1.13); C442(1.11); C558(0.96)  LDD0744  [6]
 LDCM0107  IAA HeLa H229(0.00); C966(0.00); C649(0.00); H655(0.00)  LDD0221  [11]
 LDCM0022  KB02 HEK-293T C966(1.15)  LDD1492  [13]
 LDCM0023  KB03 HEK-293T C966(1.07)  LDD1497  [13]
 LDCM0024  KB05 G361 C1131(1.11); C966(3.35); C1025(1.66); C674(2.95)  LDD3311  [14]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C966(0.67)  LDD2099  [3]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C648(0.81); C533(0.28)  LDD2100  [3]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C966(0.73)  LDD2107  [3]
 LDCM0515  Nucleophilic fragment 20b MDA-MB-231 C648(0.74)  LDD2108  [3]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C674(0.90); C966(0.41); C428(0.89)  LDD2109  [3]
 LDCM0521  Nucleophilic fragment 23b MDA-MB-231 C648(0.60); C649(0.65)  LDD2114  [3]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C648(0.55)  LDD2120  [3]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C674(1.37)  LDD2123  [3]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C966(0.56)  LDD2125  [3]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C966(0.71)  LDD2127  [3]
 LDCM0535  Nucleophilic fragment 30b MDA-MB-231 C649(0.63)  LDD2128  [3]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C428(1.19)  LDD2136  [3]
 LDCM0211  Nucleophilic fragment 3b MDA-MB-231 C966(0.28)  LDD1700  [3]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C966(0.59); C428(1.01)  LDD2140  [3]
 LDCM0549  Nucleophilic fragment 43 MDA-MB-231 C648(0.70)  LDD2143  [3]
 LDCM0003  Sulforaphane MDA-MB-231 1.60  LDD0160  [4]
 LDCM0021  THZ1 HCT 116 C366(1.26); C377(1.26); C381(1.26); C558(0.97)  LDD2173  [6]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 10 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Pachytene checkpoint protein 2 homolog (TRIP13) AAA ATPase family Q15645
Protein ABHD8 (ABHD8) AB hydrolase superfamily Q96I13
Calcium/calmodulin-dependent protein kinase type II subunit delta (CAMK2D) CAMK Ser/Thr protein kinase family Q13557
5'-AMP-activated protein kinase catalytic subunit alpha-2 (PRKAA2) CAMK Ser/Thr protein kinase family P54646
Phosphoinositide 3-kinase regulatory subunit 4 (PIK3R4) Ser/Thr protein kinase family Q99570
Dual specificity protein phosphatase 10 (DUSP10) Protein-tyrosine phosphatase family Q9Y6W6
SPRY domain-containing SOCS box protein 2 (SPSB2) SPSB family Q99619
TNF receptor-associated factor 2 (TRAF2) TNF receptor-associated factor family Q12933
Tripartite motif-containing protein 42 (TRIM42) TRIM/RBCC family Q8IWZ5
Sulfite oxidase, mitochondrial (SUOX) . P51687
Transporter and channel
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
AP-4 complex accessory subunit Tepsin (TEPSIN) . Q96N21
Bardet-Biedl syndrome 2 protein (BBS2) . Q9BXC9
Major vault protein (MVP) . Q14764
Transcription factor
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
POU domain, class 6, transcription factor 2 (POU6F2) POU transcription factor family P78424
Pogo transposable element with ZNF domain (POGZ) . Q7Z3K3
TOX high mobility group box family member 4 (TOX4) . O94842
GPCR
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Adhesion G protein-coupled receptor F5 (ADGRF5) G-protein coupled receptor 2 family Q8IZF2
Immunoglobulin
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Hyaluronan and proteoglycan link protein 2 (HAPLN2) HAPLN family Q9GZV7
Other
Click To Hide/Show 18 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Acyl carrier protein, mitochondrial (NDUFAB1) Acyl carrier protein (ACP) family O14561
GAS2-like protein 3 (GAS2L3) GAS2 family Q86XJ1
Methyl-CpG-binding domain protein 3-like 1 (MBD3L1) MBD3L family Q8WWY6
Keratin-associated protein 11-1 (KRTAP11-1) PMG family Q8IUC1
Tektin-5 (TEKT5) Tektin family Q96M29
Protein VAC14 homolog (VAC14) VAC14 family Q08AM6
AP-4 complex accessory subunit RUSC1 (RUSC1) . Q9BVN2
BRD4-interacting chromatin-remodeling complex-associated protein-like (BICRAL) . Q6AI39
Cementoblastoma-derived protein 1 (CEMP1) . Q6PRD7
Death-associated protein-like 1 (DAPL1) . A0PJW8
Kelch domain-containing protein 7B (KLHDC7B) . Q96G42
Mitochondrial coiled-coil domain protein 1 (MCCD1) . P59942
Sperm-associated microtubule inner protein 10 (SPMIP10) . Q6ZNM6
Steroid receptor-associated and regulated protein (SRARP) . Q8NEQ6
Testis-expressed protein 48 (TEX48) . A0A1B0GUV7
Ubiquitin-associated protein 2 (UBAP2) . Q5T6F2
Uncharacterized protein C10orf55 (C10orf55) . Q5SWW7
Zinc finger MYND domain-containing protein 19 (ZMYND19) . Q96E35

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
3 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
4 Competition-based, quantitative chemical proteomics in breast cancer cells identifies new target profiles for sulforaphane. Chem Commun (Camb). 2017 May 4;53(37):5182-5185. doi: 10.1039/c6cc08797c.
Mass spectrometry data entry: PXD006279
5 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
6 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
7 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
8 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
9 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
10 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
11 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
12 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
13 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
14 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840