Details of the Target

General Information of Target

Target ID LDTP15661
Target Name Zinc finger protein 592 (ZNF592)
Gene Name ZNF592
Gene ID 9640
Synonyms
KIAA0211; Zinc finger protein 592
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MELLSTPHSIEINNITCDSFRISWAMEDSDLERVTHYFIDLNKKENKNSNKFKHRDVPTK
LVAKAVPLPMTVRGHWFLSPRTEYSVAVQTAVKQSDGEYLVSGWSETVEFCTGDYAKEHL
AQLQEKAEQIAGRMLRFSVFYRNHHKEYFQHARTHCGNMLQPYLKDNSGSHGSPTSGMLH
GVFFSCNTEFNTGQPPQDSPYGRWRFQIPAQRLFNPSTNLYFADFYCMYTAYHYAILVLA
PKGSLGDRFCRDRLPLLDIACNKFLTCSVEDGELVFRHAQDLILEIIYTEPVDLSLGTLG
EISGHQLMSLSTADAKKDPSCKTCNISVGR
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
Q92610
Ensemble ID
ENST00000299927.4
HGNC ID
HGNC:28986

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 13 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
DBIA
 Probe Info  		C201(1.05); C463(1.04)  LDD0078  [2]
4-Iodoacetamidophenylacetylene
 Probe Info  		C1221(0.00); C463(0.00)  LDD0038  [3]
IA-alkyne
 Probe Info  		N.A.  LDD0162  [4]
Lodoacetamide azide
 Probe Info  		C463(0.00); C353(0.00)  LDD0037  [3]
NAIA_4
 Probe Info  		C175(0.00); C353(0.00)  LDD2226  [5]
NAIA_5
 Probe Info  		C463(0.00); C1221(0.00); C201(0.00); C175(0.00)  LDD2224  [5]
WYneN
 Probe Info  		N.A.  LDD0021  [6]
WYneO
 Probe Info  		N.A.  LDD0022  [6]
IPM
 Probe Info  		C284(0.00); C353(0.00)  LDD0147  [7]
TFBX
 Probe Info  		C823(0.00); C284(0.00)  LDD0148  [7]
Phosphinate-6
 Probe Info  		C284(0.00); C175(0.00); C463(0.00); C265(0.00)  LDD0018  [8]
AOyne
 Probe Info  		14.80  LDD0443  [9]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C201(1.12); C463(0.90); C588(1.12); C589(1.12)  LDD0531  [2]
 LDCM0215  AC10 HCT 116 C1045(0.82); C1048(0.82); C201(0.89); C463(0.97)  LDD0532  [2]
 LDCM0216  AC100 HCT 116 C1045(1.80); C1048(1.80); C201(1.09); C463(1.13)  LDD0533  [2]
 LDCM0217  AC101 HCT 116 C1045(1.55); C1048(1.55); C201(1.12); C463(0.78)  LDD0534  [2]
 LDCM0218  AC102 HCT 116 C1045(1.30); C1048(1.30); C201(1.14); C463(1.05)  LDD0535  [2]
 LDCM0219  AC103 HCT 116 C1045(1.51); C1048(1.51); C201(1.25); C463(1.48)  LDD0536  [2]
 LDCM0220  AC104 HCT 116 C1045(1.58); C1048(1.58); C201(1.11); C463(1.17)  LDD0537  [2]
 LDCM0221  AC105 HCT 116 C1045(1.49); C1048(1.49); C201(1.12); C463(1.35)  LDD0538  [2]
 LDCM0222  AC106 HCT 116 C1045(1.83); C1048(1.83); C201(1.36); C463(1.17)  LDD0539  [2]
 LDCM0223  AC107 HCT 116 C1045(1.45); C1048(1.45); C201(1.50); C463(1.80)  LDD0540  [2]
 LDCM0224  AC108 HCT 116 C1045(2.07); C1048(2.07); C201(1.27); C463(0.56)  LDD0541  [2]
 LDCM0225  AC109 HCT 116 C1045(1.32); C1048(1.32); C201(0.99); C463(0.73)  LDD0542  [2]
 LDCM0226  AC11 HCT 116 C1045(1.13); C1048(1.13); C201(1.00); C463(1.24)  LDD0543  [2]
 LDCM0227  AC110 HCT 116 C1045(1.56); C1048(1.56); C201(1.10); C463(1.01)  LDD0544  [2]
 LDCM0228  AC111 HCT 116 C1045(1.39); C1048(1.39); C201(1.11); C463(0.77)  LDD0545  [2]
 LDCM0229  AC112 HCT 116 C1045(1.39); C1048(1.39); C201(1.32); C463(1.01)  LDD0546  [2]
 LDCM0230  AC113 HCT 116 C1045(0.95); C201(0.90); C463(1.06); C588(1.05)  LDD0547  [2]
 LDCM0231  AC114 HCT 116 C1045(0.77); C201(0.69); C463(1.17); C588(0.78)  LDD0548  [2]
 LDCM0232  AC115 HCT 116 C1045(0.92); C201(0.87); C463(1.53); C588(1.01)  LDD0549  [2]
 LDCM0233  AC116 HCT 116 C1045(0.83); C201(0.78); C463(1.71); C588(0.69)  LDD0550  [2]
 LDCM0234  AC117 HCT 116 C1045(0.89); C201(1.02); C463(1.12); C588(0.78)  LDD0551  [2]
 LDCM0235  AC118 HCT 116 C1045(0.87); C201(0.95); C463(1.07); C588(1.03)  LDD0552  [2]
 LDCM0236  AC119 HCT 116 C1045(0.84); C201(0.93); C463(1.25); C588(0.96)  LDD0553  [2]
 LDCM0237  AC12 HCT 116 C1045(1.17); C1048(1.17); C201(0.87); C463(0.92)  LDD0554  [2]
 LDCM0238  AC120 HCT 116 C1045(1.08); C201(0.84); C463(1.41); C588(0.89)  LDD0555  [2]
 LDCM0239  AC121 HCT 116 C1045(0.85); C201(0.91); C463(1.11); C588(0.69)  LDD0556  [2]
 LDCM0240  AC122 HCT 116 C1045(1.31); C201(0.80); C463(1.09); C588(1.05)  LDD0557  [2]
 LDCM0241  AC123 HCT 116 C1045(0.88); C201(1.05); C463(1.12); C588(0.89)  LDD0558  [2]
 LDCM0242  AC124 HCT 116 C1045(0.81); C201(0.94); C463(1.31); C588(0.97)  LDD0559  [2]
 LDCM0243  AC125 HCT 116 C1045(0.97); C201(0.93); C463(1.07); C588(0.95)  LDD0560  [2]
 LDCM0244  AC126 HCT 116 C1045(0.88); C201(0.81); C463(1.57); C588(0.90)  LDD0561  [2]
 LDCM0245  AC127 HCT 116 C1045(0.95); C201(0.97); C463(1.37); C588(0.93)  LDD0562  [2]
 LDCM0246  AC128 HCT 116 C1045(1.01); C1048(1.01); C201(1.17); C463(0.57)  LDD0563  [2]
 LDCM0247  AC129 HCT 116 C1045(1.07); C1048(1.07); C201(0.84); C463(0.52)  LDD0564  [2]
 LDCM0249  AC130 HCT 116 C1045(1.08); C1048(1.08); C201(1.11); C463(0.54)  LDD0566  [2]
 LDCM0250  AC131 HCT 116 C1045(1.15); C1048(1.15); C201(0.92); C463(0.78)  LDD0567  [2]
 LDCM0251  AC132 HCT 116 C1045(1.13); C1048(1.13); C201(0.87); C463(0.56)  LDD0568  [2]
 LDCM0252  AC133 HCT 116 C1045(1.03); C1048(1.03); C201(0.93); C463(0.55)  LDD0569  [2]
 LDCM0253  AC134 HCT 116 C1045(1.12); C1048(1.12); C201(1.05); C463(0.53)  LDD0570  [2]
 LDCM0254  AC135 HCT 116 C1045(1.35); C1048(1.35); C201(1.07); C463(0.55)  LDD0571  [2]
 LDCM0255  AC136 HCT 116 C1045(1.17); C1048(1.17); C201(1.04); C463(0.56)  LDD0572  [2]
 LDCM0256  AC137 HCT 116 C1045(1.26); C1048(1.26); C201(0.86); C463(0.45)  LDD0573  [2]
 LDCM0257  AC138 HCT 116 C1045(1.70); C1048(1.70); C201(0.96); C463(0.55)  LDD0574  [2]
 LDCM0258  AC139 HCT 116 C1045(1.28); C1048(1.28); C201(0.99); C463(0.60)  LDD0575  [2]
 LDCM0259  AC14 HCT 116 C1045(1.01); C1048(1.01); C201(1.08); C463(1.01)  LDD0576  [2]
 LDCM0260  AC140 HCT 116 C1045(1.55); C1048(1.55); C201(0.96); C463(0.62)  LDD0577  [2]
 LDCM0261  AC141 HCT 116 C1045(1.45); C1048(1.45); C201(0.90); C463(0.68)  LDD0578  [2]
 LDCM0262  AC142 HCT 116 C1045(1.34); C1048(1.34); C201(0.78); C463(0.44)  LDD0579  [2]
 LDCM0263  AC143 HCT 116 C1045(0.92); C1048(0.92); C769(1.00); C777(1.00)  LDD0580  [2]
 LDCM0264  AC144 HCT 116 C588(0.93); C592(0.93); C1045(0.93); C1048(0.93)  LDD0581  [2]
 LDCM0265  AC145 HCT 116 C1045(0.69); C1048(0.69); C769(0.88); C777(0.88)  LDD0582  [2]
 LDCM0266  AC146 HCT 116 C1045(0.62); C1048(0.62); C588(0.90); C592(0.90)  LDD0583  [2]
 LDCM0267  AC147 HCT 116 C1045(0.60); C1048(0.60); C588(0.93); C592(0.93)  LDD0584  [2]
 LDCM0268  AC148 HCT 116 C1045(0.69); C1048(0.69); C588(1.10); C592(1.10)  LDD0585  [2]
 LDCM0269  AC149 HCT 116 C1045(0.56); C1048(0.56); C588(1.11); C592(1.11)  LDD0586  [2]
 LDCM0270  AC15 HCT 116 C588(0.85); C589(0.85); C592(0.85); C463(0.94)  LDD0587  [2]
 LDCM0271  AC150 HCT 116 C1045(0.72); C1048(0.72); C769(1.01); C777(1.01)  LDD0588  [2]
 LDCM0272  AC151 HCT 116 C588(0.91); C592(0.91); C769(1.08); C777(1.08)  LDD0589  [2]
 LDCM0273  AC152 HCT 116 C1045(0.66); C1048(0.66); C588(0.85); C592(0.85)  LDD0590  [2]
 LDCM0274  AC153 HCT 116 C1045(0.80); C1048(0.80); C589(1.17); C588(1.21)  LDD0591  [2]
 LDCM0621  AC154 HCT 116 C1045(0.77); C1048(0.77); C201(1.33); C463(1.73)  LDD2158  [2]
 LDCM0622  AC155 HCT 116 C1045(0.86); C1048(0.86); C201(1.65); C463(1.55)  LDD2159  [2]
 LDCM0623  AC156 HCT 116 C1045(0.60); C1048(0.60); C201(1.14); C463(1.27)  LDD2160  [2]
 LDCM0624  AC157 HCT 116 C1045(0.65); C1048(0.65); C201(1.35); C463(1.18)  LDD2161  [2]
 LDCM0276  AC17 HCT 116 C829(0.85); C832(0.85); C823(0.86); C769(0.93)  LDD0593  [2]
 LDCM0277  AC18 HCT 116 C829(0.93); C832(0.93); C823(0.97); C769(1.11)  LDD0594  [2]
 LDCM0278  AC19 HCT 116 C829(0.93); C832(0.93); C823(0.94); C588(1.13)  LDD0595  [2]
 LDCM0279  AC2 HCT 116 C463(0.89); C588(0.91); C589(0.91); C592(0.91)  LDD0596  [2]
 LDCM0280  AC20 HCT 116 C823(0.88); C829(0.93); C832(0.93); C588(1.01)  LDD0597  [2]
 LDCM0281  AC21 HCT 116 C823(0.74); C829(0.89); C832(0.89); C588(1.08)  LDD0598  [2]
 LDCM0282  AC22 HCT 116 C823(0.77); C829(0.95); C832(0.95); C769(1.03)  LDD0599  [2]
 LDCM0283  AC23 HCT 116 C823(0.75); C588(0.83); C589(0.83); C592(0.83)  LDD0600  [2]
 LDCM0284  AC24 HCT 116 C829(0.88); C832(0.88); C648(0.99); C823(0.99)  LDD0601  [2]
 LDCM0285  AC25 HCT 116 C829(0.70); C832(0.70); C588(0.84); C589(0.84)  LDD0602  [2]
 LDCM0286  AC26 HCT 116 C829(0.58); C832(0.58); C588(0.63); C589(0.63)  LDD0603  [2]
 LDCM0287  AC27 HCT 116 C588(0.59); C589(0.59); C592(0.59); C829(0.64)  LDD0604  [2]
 LDCM0288  AC28 HCT 116 C829(0.62); C832(0.62); C648(0.76); C588(0.76)  LDD0605  [2]
 LDCM0289  AC29 HCT 116 C588(0.46); C589(0.46); C592(0.46); C829(0.61)  LDD0606  [2]
 LDCM0290  AC3 HCT 116 C463(0.83); C588(0.91); C589(0.91); C592(0.91)  LDD0607  [2]
 LDCM0291  AC30 HCT 116 C588(0.45); C589(0.45); C592(0.45); C829(0.54)  LDD0608  [2]
 LDCM0292  AC31 HCT 116 C588(0.49); C589(0.49); C592(0.49); C829(0.67)  LDD0609  [2]
 LDCM0293  AC32 HCT 116 C588(0.49); C589(0.49); C592(0.49); C829(0.55)  LDD0610  [2]
 LDCM0294  AC33 HCT 116 C588(0.64); C589(0.64); C592(0.64); C829(0.65)  LDD0611  [2]
 LDCM0295  AC34 HCT 116 C829(0.59); C832(0.59); C588(0.67); C589(0.67)  LDD0612  [2]
 LDCM0296  AC35 HCT 116 C463(0.51); C773(0.71); C769(0.82); C777(0.82)  LDD0613  [2]
 LDCM0297  AC36 HCT 116 C463(0.55); C589(0.69); C592(0.75); C770(0.78)  LDD0614  [2]
 LDCM0298  AC37 HCT 116 C463(0.56); C770(0.69); C773(0.79); C589(0.90)  LDD0615  [2]
 LDCM0299  AC38 HCT 116 C463(0.89); C769(0.96); C777(0.96); C773(0.96)  LDD0616  [2]
 LDCM0300  AC39 HCT 116 C463(0.76); C589(0.86); C829(0.88); C832(0.88)  LDD0617  [2]
 LDCM0301  AC4 HCT 116 C463(0.77); C588(0.86); C589(0.86); C592(0.86)  LDD0618  [2]
 LDCM0302  AC40 HCT 116 C463(0.82); C588(0.89); C592(0.95); C773(0.96)  LDD0619  [2]
 LDCM0303  AC41 HCT 116 C463(0.82); C773(0.85); C588(0.88); C770(0.89)  LDD0620  [2]
 LDCM0304  AC42 HCT 116 C463(0.71); C829(0.91); C832(0.91); C770(0.97)  LDD0621  [2]
 LDCM0305  AC43 HCT 116 C463(0.69); C588(0.91); C592(0.92); C773(0.93)  LDD0622  [2]
 LDCM0306  AC44 HCT 116 C463(0.66); C588(0.88); C592(0.97); C829(1.04)  LDD0623  [2]
 LDCM0307  AC45 HCT 116 C773(0.84); C769(0.84); C777(0.84); C588(0.88)  LDD0624  [2]
 LDCM0308  AC46 HCT 116 C829(0.97); C832(0.97); C648(1.04); C201(1.24)  LDD0625  [2]
 LDCM0309  AC47 HCT 116 C829(0.90); C832(0.90); C648(1.04); C201(1.11)  LDD0626  [2]
 LDCM0310  AC48 HCT 116 C829(0.98); C832(0.98); C648(1.16); C201(1.23)  LDD0627  [2]
 LDCM0311  AC49 HCT 116 C829(0.99); C832(0.99); C201(1.05); C648(1.30)  LDD0628  [2]
 LDCM0312  AC5 HCT 116 C463(0.79); C588(0.90); C589(0.90); C592(0.90)  LDD0629  [2]
 LDCM0313  AC50 HCT 116 C201(0.89); C829(1.03); C832(1.03); C648(1.35)  LDD0630  [2]
 LDCM0314  AC51 HCT 116 C648(0.73); C201(0.81); C829(1.06); C832(1.06)  LDD0631  [2]
 LDCM0315  AC52 HCT 116 C829(0.96); C832(0.96); C201(0.96); C648(0.99)  LDD0632  [2]
 LDCM0316  AC53 HCT 116 C829(0.93); C832(0.93); C648(1.15); C201(1.15)  LDD0633  [2]
 LDCM0317  AC54 HCT 116 C648(1.02); C829(1.03); C832(1.03); C201(1.07)  LDD0634  [2]
 LDCM0318  AC55 HCT 116 C829(0.84); C832(0.84); C201(1.03); C648(1.21)  LDD0635  [2]
 LDCM0319  AC56 HCT 116 C829(0.92); C832(0.92); C201(1.22); C648(1.59)  LDD0636  [2]
 LDCM0320  AC57 HCT 116 C829(0.81); C832(0.81); C588(1.10); C589(1.10)  LDD0637  [2]
 LDCM0321  AC58 HCT 116 C829(0.87); C832(0.87); C588(0.94); C589(0.94)  LDD0638  [2]
 LDCM0322  AC59 HCT 116 C829(0.82); C832(0.82); C588(0.97); C589(0.97)  LDD0639  [2]
 LDCM0323  AC6 HCT 116 C588(0.90); C589(0.90); C592(0.90); C1045(0.92)  LDD0640  [2]
 LDCM0324  AC60 HCT 116 C829(0.82); C832(0.82); C588(1.18); C589(1.18)  LDD0641  [2]
 LDCM0325  AC61 HCT 116 C829(0.91); C832(0.91); C463(1.09); C588(1.22)  LDD0642  [2]
 LDCM0326  AC62 HCT 116 C829(0.93); C832(0.93); C588(1.11); C589(1.11)  LDD0643  [2]
 LDCM0327  AC63 HCT 116 C829(0.83); C832(0.83); C463(1.03); C588(1.19)  LDD0644  [2]
 LDCM0328  AC64 HCT 116 C829(0.79); C832(0.79); C769(1.33); C773(1.33)  LDD0645  [2]
 LDCM0329  AC65 HCT 116 C463(0.56); C829(0.90); C832(0.90); C588(1.23)  LDD0646  [2]
 LDCM0330  AC66 HCT 116 C463(0.54); C829(0.93); C832(0.93); C588(1.04)  LDD0647  [2]
 LDCM0331  AC67 HCT 116 C463(0.64); C829(0.71); C832(0.71); C588(1.14)  LDD0648  [2]
 LDCM0332  AC68 HCT 116 C1045(0.92); C1048(0.92); C588(0.97); C589(0.97)  LDD0649  [2]
 LDCM0333  AC69 HCT 116 C1045(0.83); C1048(0.83); C823(1.02); C829(1.07)  LDD0650  [2]
 LDCM0334  AC7 HCT 116 C201(0.84); C1045(0.94); C1048(0.94); C588(0.99)  LDD0651  [2]
 LDCM0335  AC70 HCT 116 C769(0.81); C770(0.81); C773(0.81); C823(0.83)  LDD0652  [2]
 LDCM0336  AC71 HCT 116 C1045(0.85); C1048(0.85); C201(0.94); C588(1.01)  LDD0653  [2]
 LDCM0337  AC72 HCT 116 C829(0.89); C832(0.89); C769(1.02); C770(1.02)  LDD0654  [2]
 LDCM0338  AC73 HCT 116 C829(0.82); C832(0.82); C1045(0.99); C1048(0.99)  LDD0655  [2]
 LDCM0339  AC74 HCT 116 C1045(0.76); C1048(0.76); C829(1.01); C832(1.01)  LDD0656  [2]
 LDCM0340  AC75 HCT 116 C829(0.89); C832(0.89); C769(0.93); C770(0.93)  LDD0657  [2]
 LDCM0341  AC76 HCT 116 C829(0.79); C832(0.79); C1045(0.82); C1048(0.82)  LDD0658  [2]
 LDCM0342  AC77 HCT 116 C1045(0.81); C1048(0.81); C829(0.93); C832(0.93)  LDD0659  [2]
 LDCM0343  AC78 HCT 116 C1045(0.84); C1048(0.84); C829(0.85); C832(0.85)  LDD0660  [2]
 LDCM0344  AC79 HCT 116 C769(0.93); C770(0.93); C773(0.93); C829(0.95)  LDD0661  [2]
 LDCM0345  AC8 HCT 116 C829(0.93); C832(0.93); C1045(0.98); C1048(0.98)  LDD0662  [2]
 LDCM0346  AC80 HCT 116 C829(0.75); C832(0.75); C1045(0.80); C1048(0.80)  LDD0663  [2]
 LDCM0347  AC81 HCT 116 C829(0.80); C832(0.80); C1045(1.05); C1048(1.05)  LDD0664  [2]
 LDCM0348  AC82 HCT 116 C1045(0.79); C1048(0.79); C829(0.83); C832(0.83)  LDD0665  [2]
 LDCM0349  AC83 HCT 116 C770(0.71); C773(0.71); C829(0.74); C832(0.74)  LDD0666  [2]
 LDCM0350  AC84 HCT 116 C770(0.66); C773(0.66); C588(0.87); C589(0.87)  LDD0667  [2]
 LDCM0351  AC85 HCT 116 C829(0.58); C832(0.58); C770(0.69); C773(0.69)  LDD0668  [2]
 LDCM0352  AC86 HCT 116 C829(0.60); C832(0.60); C770(0.70); C773(0.70)  LDD0669  [2]
 LDCM0353  AC87 HCT 116 C770(0.55); C773(0.55); C829(0.64); C832(0.64)  LDD0670  [2]
 LDCM0354  AC88 HCT 116 C829(0.48); C832(0.48); C770(0.52); C773(0.52)  LDD0671  [2]
 LDCM0355  AC89 HCT 116 C770(0.55); C773(0.55); C829(0.61); C832(0.61)  LDD0672  [2]
 LDCM0357  AC90 HCT 116 C829(0.51); C832(0.51); C770(0.60); C773(0.60)  LDD0674  [2]
 LDCM0358  AC91 HCT 116 C770(0.71); C773(0.71); C588(0.83); C589(0.83)  LDD0675  [2]
 LDCM0359  AC92 HCT 116 C829(0.75); C832(0.75); C588(0.76); C589(0.76)  LDD0676  [2]
 LDCM0360  AC93 HCT 116 C770(0.52); C773(0.52); C829(0.66); C832(0.66)  LDD0677  [2]
 LDCM0361  AC94 HCT 116 C770(0.74); C773(0.74); C588(0.79); C589(0.79)  LDD0678  [2]
 LDCM0362  AC95 HCT 116 C829(0.53); C832(0.53); C770(0.59); C773(0.59)  LDD0679  [2]
 LDCM0363  AC96 HCT 116 C770(0.53); C773(0.53); C588(0.88); C589(0.88)  LDD0680  [2]
 LDCM0364  AC97 HCT 116 C829(0.54); C832(0.54); C770(0.63); C773(0.63)  LDD0681  [2]
 LDCM0365  AC98 HCT 116 C829(0.46); C832(0.46); C201(1.34); C1045(1.75)  LDD0682  [2]
 LDCM0366  AC99 HCT 116 C829(0.46); C832(0.46); C463(0.80); C201(1.09)  LDD0683  [2]
 LDCM0248  AKOS034007472 HCT 116 C1045(1.01); C1048(1.01); C201(0.93); C463(0.95)  LDD0565  [2]
 LDCM0356  AKOS034007680 HCT 116 C201(0.84); C588(0.96); C589(0.96); C592(0.96)  LDD0673  [2]
 LDCM0275  AKOS034007705 HCT 116 C463(0.90); C588(0.91); C589(0.91); C592(0.91)  LDD0592  [2]
 LDCM0156  Aniline NCI-H1299 14.86  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C201(1.05); C463(1.04)  LDD0078  [2]
 LDCM0632  CL-Sc Hep-G2 C175(0.90); C201(0.51)  LDD2227  [5]
 LDCM0367  CL1 HCT 116 C829(0.68); C832(0.68); C588(0.69); C589(0.69)  LDD0684  [2]
 LDCM0368  CL10 HCT 116 C829(0.71); C832(0.71); C201(0.97); C823(0.98)  LDD0685  [2]
 LDCM0369  CL100 HCT 116 C770(0.87); C777(0.87); C588(0.89); C589(0.89)  LDD0686  [2]
 LDCM0370  CL101 HCT 116 C463(0.88); C201(0.91); C588(0.97); C589(0.97)  LDD0687  [2]
 LDCM0371  CL102 HCT 116 C201(0.74); C588(0.84); C589(0.84); C592(0.84)  LDD0688  [2]
 LDCM0372  CL103 HCT 116 C201(0.82); C588(0.87); C589(0.87); C592(0.87)  LDD0689  [2]
 LDCM0373  CL104 HCT 116 C201(0.81); C588(0.93); C589(0.93); C592(0.93)  LDD0690  [2]
 LDCM0374  CL105 HCT 116 C829(0.80); C832(0.80); C823(0.82); C1045(0.95)  LDD0691  [2]
 LDCM0375  CL106 HCT 116 C829(0.92); C832(0.92); C1045(0.97); C823(1.05)  LDD0692  [2]
 LDCM0376  CL107 HCT 116 C829(0.70); C832(0.70); C588(0.84); C589(0.84)  LDD0693  [2]
 LDCM0377  CL108 HCT 116 C829(0.76); C832(0.76); C823(0.83); C588(0.98)  LDD0694  [2]
 LDCM0378  CL109 HCT 116 C823(0.78); C829(0.80); C832(0.80); C588(0.90)  LDD0695  [2]
 LDCM0379  CL11 HCT 116 C829(0.63); C832(0.63); C823(0.84); C588(0.91)  LDD0696  [2]
 LDCM0380  CL110 HCT 116 C829(0.73); C832(0.73); C1045(0.78); C823(0.81)  LDD0697  [2]
 LDCM0381  CL111 HCT 116 C829(0.78); C832(0.78); C1045(0.91); C588(1.04)  LDD0698  [2]
 LDCM0382  CL112 HCT 116 C588(0.61); C589(0.61); C592(0.61); C829(0.65)  LDD0699  [2]
 LDCM0383  CL113 HCT 116 C588(0.53); C589(0.53); C592(0.53); C829(0.54)  LDD0700  [2]
 LDCM0384  CL114 HCT 116 C588(0.43); C589(0.43); C592(0.43); C829(0.57)  LDD0701  [2]
 LDCM0385  CL115 HCT 116 C588(0.43); C589(0.43); C592(0.43); C829(0.58)  LDD0702  [2]
 LDCM0386  CL116 HCT 116 C829(0.63); C832(0.63); C823(0.70); C588(0.73)  LDD0703  [2]
 LDCM0387  CL117 HCT 116 C769(1.03); C777(1.03); C589(1.08); C592(1.09)  LDD0704  [2]
 LDCM0388  CL118 HCT 116 C463(0.75); C773(0.96); C588(0.96); C592(0.96)  LDD0705  [2]
 LDCM0389  CL119 HCT 116 C769(0.90); C777(0.90); C773(0.91); C588(1.00)  LDD0706  [2]
 LDCM0390  CL12 HCT 116 C829(0.73); C832(0.73); C588(0.80); C589(0.80)  LDD0707  [2]
 LDCM0391  CL120 HCT 116 C463(0.61); C769(0.89); C777(0.89); C589(0.93)  LDD0708  [2]
 LDCM0392  CL121 HCT 116 C648(0.83); C201(1.25); C829(1.26); C832(1.26)  LDD0709  [2]
 LDCM0393  CL122 HCT 116 C829(0.98); C832(0.98); C201(1.00); C648(1.21)  LDD0710  [2]
 LDCM0394  CL123 HCT 116 C829(0.88); C832(0.88); C201(1.14); C648(1.33)  LDD0711  [2]
 LDCM0395  CL124 HCT 116 C829(0.94); C832(0.94); C201(1.12); C648(1.27)  LDD0712  [2]
 LDCM0396  CL125 HCT 116 C463(0.81); C829(0.89); C832(0.89); C588(1.05)  LDD0713  [2]
 LDCM0397  CL126 HCT 116 C588(0.96); C589(0.96); C592(0.96); C463(0.97)  LDD0714  [2]
 LDCM0398  CL127 HCT 116 C829(0.91); C832(0.91); C463(0.95); C588(1.00)  LDD0715  [2]
 LDCM0399  CL128 HCT 116 C829(0.74); C832(0.74); C588(1.06); C589(1.06)  LDD0716  [2]
 LDCM0400  CL13 HCT 116 C829(0.81); C832(0.81); C201(0.91); C823(1.05)  LDD0717  [2]
 LDCM0401  CL14 HCT 116 C588(0.78); C589(0.78); C592(0.78); C829(0.79)  LDD0718  [2]
 LDCM0402  CL15 HCT 116 C588(0.91); C589(0.91); C592(0.91); C201(0.99)  LDD0719  [2]
 LDCM0403  CL16 HCT 116 C829(0.80); C832(0.80); C463(0.88); C769(0.92)  LDD0720  [2]
 LDCM0404  CL17 HCT 116 C463(0.73); C769(0.92); C773(0.92); C201(0.98)  LDD0721  [2]
 LDCM0405  CL18 HCT 116 C463(0.80); C201(0.92); C769(1.15); C773(1.15)  LDD0722  [2]
 LDCM0406  CL19 HCT 116 C769(0.74); C773(0.74); C463(1.00); C201(1.05)  LDD0723  [2]
 LDCM0407  CL2 HCT 116 C829(0.81); C832(0.81); C201(0.91); C823(0.93)  LDD0724  [2]
 LDCM0408  CL20 HCT 116 C769(0.72); C773(0.72); C463(0.77); C588(1.05)  LDD0725  [2]
 LDCM0409  CL21 HCT 116 C463(0.78); C201(1.01); C1045(1.09); C1048(1.09)  LDD0726  [2]
 LDCM0410  CL22 HCT 116 C463(0.65); C769(1.02); C773(1.02); C201(1.09)  LDD0727  [2]
 LDCM0411  CL23 HCT 116 C769(0.74); C773(0.74); C463(0.79); C588(1.10)  LDD0728  [2]
 LDCM0412  CL24 HCT 116 C1045(1.16); C1048(1.16); C201(1.09); C463(0.58)  LDD0729  [2]
 LDCM0413  CL25 HCT 116 C1045(1.16); C1048(1.16); C201(0.98); C463(0.65)  LDD0730  [2]
 LDCM0414  CL26 HCT 116 C1045(1.15); C1048(1.15); C201(1.05); C463(0.91)  LDD0731  [2]
 LDCM0415  CL27 HCT 116 C1045(1.22); C1048(1.22); C201(1.02); C463(0.72)  LDD0732  [2]
 LDCM0416  CL28 HCT 116 C1045(1.25); C1048(1.25); C201(1.08); C463(0.75)  LDD0733  [2]
 LDCM0417  CL29 HCT 116 C1045(1.18); C1048(1.18); C201(1.06); C463(0.56)  LDD0734  [2]
 LDCM0418  CL3 HCT 116 C201(0.99); C463(1.13); C588(0.85); C589(0.85)  LDD0735  [2]
 LDCM0419  CL30 HCT 116 C1045(1.37); C1048(1.37); C201(1.05); C463(0.60)  LDD0736  [2]
 LDCM0420  CL31 HCT 116 C1045(1.23); C1048(1.23); C201(0.97); C463(0.68)  LDD0737  [2]
 LDCM0421  CL32 HCT 116 C1045(1.43); C1048(1.43); C201(1.08); C463(0.97)  LDD0738  [2]
 LDCM0422  CL33 HCT 116 C1045(0.82); C1048(0.82); C201(1.08); C463(0.86)  LDD0739  [2]
 LDCM0423  CL34 HCT 116 C1045(1.03); C1048(1.03); C201(1.17); C463(0.86)  LDD0740  [2]
 LDCM0424  CL35 HCT 116 C1045(0.99); C1048(0.99); C201(1.23); C463(0.94)  LDD0741  [2]
 LDCM0425  CL36 HCT 116 C1045(1.19); C1048(1.19); C201(1.20); C463(0.75)  LDD0742  [2]
 LDCM0426  CL37 HCT 116 C1045(1.28); C1048(1.28); C201(1.29); C463(0.86)  LDD0743  [2]
 LDCM0428  CL39 HCT 116 C1045(0.99); C1048(0.99); C201(1.25); C463(0.96)  LDD0745  [2]
 LDCM0429  CL4 HCT 116 C201(0.99); C463(0.97); C588(1.00); C589(1.00)  LDD0746  [2]
 LDCM0430  CL40 HCT 116 C1045(1.01); C1048(1.01); C201(1.24); C463(0.83)  LDD0747  [2]
 LDCM0431  CL41 HCT 116 C1045(1.10); C1048(1.10); C201(1.26); C463(0.89)  LDD0748  [2]
 LDCM0432  CL42 HCT 116 C1045(0.79); C1048(0.79); C201(1.36); C463(0.80)  LDD0749  [2]
 LDCM0433  CL43 HCT 116 C1045(1.32); C1048(1.32); C201(1.29); C463(0.98)  LDD0750  [2]
 LDCM0434  CL44 HCT 116 C1045(1.21); C1048(1.21); C201(1.21); C463(0.88)  LDD0751  [2]
 LDCM0435  CL45 HCT 116 C1045(1.07); C1048(1.07); C201(1.18); C463(0.91)  LDD0752  [2]
 LDCM0436  CL46 HCT 116 C1045(1.18); C1048(1.18); C201(0.84); C463(0.73)  LDD0753  [2]
 LDCM0437  CL47 HCT 116 C1045(0.86); C1048(0.86); C201(1.03); C463(0.74)  LDD0754  [2]
 LDCM0438  CL48 HCT 116 C1045(0.76); C1048(0.76); C201(1.16); C463(0.83)  LDD0755  [2]
 LDCM0439  CL49 HCT 116 C1045(1.37); C1048(1.37); C201(0.97); C463(0.64)  LDD0756  [2]
 LDCM0440  CL5 HCT 116 C201(1.09); C463(1.06); C588(0.84); C589(0.84)  LDD0757  [2]
 LDCM0441  CL50 HCT 116 C1045(0.55); C1048(0.55); C201(1.24); C463(0.73)  LDD0758  [2]
 LDCM0442  CL51 HCT 116 C1045(0.98); C1048(0.98); C201(1.14); C463(0.69)  LDD0759  [2]
 LDCM0443  CL52 HCT 116 C1045(1.05); C1048(1.05); C201(1.29); C463(0.80)  LDD0760  [2]
 LDCM0444  CL53 HCT 116 C1045(0.76); C1048(0.76); C201(1.29); C463(0.75)  LDD0761  [2]
 LDCM0445  CL54 HCT 116 C1045(0.65); C1048(0.65); C201(1.01); C463(0.65)  LDD0762  [2]
 LDCM0446  CL55 HCT 116 C1045(1.19); C1048(1.19); C201(0.93); C463(0.68)  LDD0763  [2]
 LDCM0447  CL56 HCT 116 C1045(1.22); C1048(1.22); C201(1.05); C463(0.70)  LDD0764  [2]
 LDCM0448  CL57 HCT 116 C1045(0.82); C1048(0.82); C201(1.09); C463(0.70)  LDD0765  [2]
 LDCM0449  CL58 HCT 116 C1045(0.86); C1048(0.86); C201(1.13); C463(0.72)  LDD0766  [2]
 LDCM0450  CL59 HCT 116 C1045(0.96); C1048(0.96); C201(0.90); C463(0.76)  LDD0767  [2]
 LDCM0451  CL6 HCT 116 C201(0.89); C463(1.22); C588(1.11); C589(1.11)  LDD0768  [2]
 LDCM0452  CL60 HCT 116 C1045(0.93); C1048(0.93); C201(1.05); C463(0.69)  LDD0769  [2]
 LDCM0453  CL61 HCT 116 C201(1.07); C463(0.77); C588(0.91); C589(0.91)  LDD0770  [2]
 LDCM0454  CL62 HCT 116 C201(1.02); C463(1.06); C588(0.94); C589(0.94)  LDD0771  [2]
 LDCM0455  CL63 HCT 116 C201(1.04); C463(1.15); C588(0.96); C589(0.96)  LDD0772  [2]
 LDCM0456  CL64 HCT 116 C201(1.13); C463(0.62); C588(0.80); C589(0.80)  LDD0773  [2]
 LDCM0457  CL65 HCT 116 C201(1.14); C463(0.82); C588(0.88); C589(0.88)  LDD0774  [2]
 LDCM0458  CL66 HCT 116 C201(1.23); C463(0.86); C588(0.88); C589(0.88)  LDD0775  [2]
 LDCM0459  CL67 HCT 116 C201(1.31); C463(0.80); C588(0.93); C589(0.93)  LDD0776  [2]
 LDCM0460  CL68 HCT 116 C201(1.46); C463(0.69); C588(0.98); C589(0.98)  LDD0777  [2]
 LDCM0461  CL69 HCT 116 C201(1.12); C463(0.82); C588(1.29); C589(1.29)  LDD0778  [2]
 LDCM0462  CL7 HCT 116 C201(0.81); C463(1.37); C588(0.82); C589(0.82)  LDD0779  [2]
 LDCM0463  CL70 HCT 116 C201(1.36); C463(0.91); C588(1.02); C589(1.02)  LDD0780  [2]
 LDCM0464  CL71 HCT 116 C201(1.25); C463(0.78); C588(0.98); C589(0.98)  LDD0781  [2]
 LDCM0465  CL72 HCT 116 C201(1.33); C463(0.92); C588(0.96); C589(0.96)  LDD0782  [2]
 LDCM0466  CL73 HCT 116 C201(1.33); C463(0.97); C588(0.95); C589(0.95)  LDD0783  [2]
 LDCM0467  CL74 HCT 116 C201(1.40); C463(0.90); C588(0.92); C589(0.92)  LDD0784  [2]
 LDCM0469  CL76 HCT 116 C1045(0.80); C1048(0.80); C201(1.00); C463(1.11)  LDD0786  [2]
 LDCM0470  CL77 HCT 116 C1045(0.63); C1048(0.63); C201(0.96); C463(1.08)  LDD0787  [2]
 LDCM0471  CL78 HCT 116 C1045(0.68); C1048(0.68); C201(1.08); C463(1.04)  LDD0788  [2]
 LDCM0472  CL79 HCT 116 C1045(0.75); C1048(0.75); C201(1.35); C463(0.93)  LDD0789  [2]
 LDCM0473  CL8 HCT 116 C201(1.21); C463(1.31); C588(0.75); C589(0.75)  LDD0790  [2]
 LDCM0474  CL80 HCT 116 C1045(0.68); C1048(0.68); C201(0.86); C463(0.95)  LDD0791  [2]
 LDCM0475  CL81 HCT 116 C1045(0.71); C1048(0.71); C201(1.09); C463(1.00)  LDD0792  [2]
 LDCM0476  CL82 HCT 116 C1045(0.82); C1048(0.82); C201(1.28); C463(0.87)  LDD0793  [2]
 LDCM0477  CL83 HCT 116 C1045(0.64); C1048(0.64); C201(1.11); C463(0.87)  LDD0794  [2]
 LDCM0478  CL84 HCT 116 C1045(0.83); C1048(0.83); C201(1.06); C463(1.00)  LDD0795  [2]
 LDCM0479  CL85 HCT 116 C1045(0.63); C1048(0.63); C201(1.19); C463(0.95)  LDD0796  [2]
 LDCM0480  CL86 HCT 116 C1045(0.66); C1048(0.66); C201(0.99); C463(0.95)  LDD0797  [2]
 LDCM0481  CL87 HCT 116 C1045(0.69); C1048(0.69); C201(0.94); C463(0.95)  LDD0798  [2]
 LDCM0482  CL88 HCT 116 C1045(0.77); C1048(0.77); C201(1.15); C463(0.99)  LDD0799  [2]
 LDCM0483  CL89 HCT 116 C1045(0.84); C1048(0.84); C201(1.61); C463(0.96)  LDD0800  [2]
 LDCM0484  CL9 HCT 116 C201(1.08); C463(1.20); C588(0.81); C589(0.81)  LDD0801  [2]
 LDCM0485  CL90 HCT 116 C1045(0.63); C1048(0.63); C201(1.22); C463(0.94)  LDD0802  [2]
 LDCM0486  CL91 HCT 116 C201(1.27); C463(0.88); C588(0.85); C589(0.85)  LDD0803  [2]
 LDCM0487  CL92 HCT 116 C201(1.26); C463(0.91); C588(0.94); C589(0.94)  LDD0804  [2]
 LDCM0488  CL93 HCT 116 C201(1.15); C463(0.70); C588(0.94); C589(0.94)  LDD0805  [2]
 LDCM0489  CL94 HCT 116 C201(1.19); C463(0.97); C588(0.82); C589(0.82)  LDD0806  [2]
 LDCM0490  CL95 HCT 116 C201(1.25); C463(0.75); C588(0.90); C589(0.90)  LDD0807  [2]
 LDCM0491  CL96 HCT 116 C201(1.11); C463(0.75); C588(1.01); C589(1.01)  LDD0808  [2]
 LDCM0492  CL97 HCT 116 C201(1.15); C463(0.85); C588(0.87); C589(0.87)  LDD0809  [2]
 LDCM0493  CL98 HCT 116 C201(1.27); C463(0.98); C588(0.89); C589(0.89)  LDD0810  [2]
 LDCM0494  CL99 HCT 116 C201(1.20); C463(1.17); C588(0.96); C589(0.96)  LDD0811  [2]
 LDCM0495  E2913 HEK-293T C463(1.02); C790(1.17); C823(1.01); C107(0.97)  LDD1698  [10]
 LDCM0625  F8 Ramos C463(1.50)  LDD2187  [11]
 LDCM0572  Fragment10 Ramos C463(0.85)  LDD2189  [11]
 LDCM0573  Fragment11 Ramos C463(14.96)  LDD2190  [11]
 LDCM0574  Fragment12 Ramos C463(0.52)  LDD2191  [11]
 LDCM0576  Fragment14 Ramos C463(0.84)  LDD2193  [11]
 LDCM0579  Fragment20 Ramos C463(0.48)  LDD2194  [11]
 LDCM0580  Fragment21 Ramos C463(0.73)  LDD2195  [11]
 LDCM0582  Fragment23 Ramos C463(0.98)  LDD2196  [11]
 LDCM0588  Fragment30 Ramos C463(1.11)  LDD2199  [11]
 LDCM0590  Fragment32 Ramos C463(1.24)  LDD2201  [11]
 LDCM0468  Fragment33 HCT 116 C201(1.07); C463(0.89); C588(1.08); C589(1.08)  LDD0785  [2]
 LDCM0596  Fragment38 Ramos C463(0.47)  LDD2203  [11]
 LDCM0566  Fragment4 Ramos C463(0.73)  LDD2184  [11]
 LDCM0427  Fragment51 HCT 116 C1045(1.22); C1048(1.22); C201(1.43); C463(0.61)  LDD0744  [2]
 LDCM0610  Fragment52 Ramos C463(1.05)  LDD2204  [11]
 LDCM0614  Fragment56 Ramos C463(0.98)  LDD2205  [11]
 LDCM0569  Fragment7 Ramos C463(1.01)  LDD2186  [11]
 LDCM0571  Fragment9 Ramos C463(0.47)  LDD2188  [11]
 LDCM0022  KB02 HCT 116 C588(3.89); C592(3.89); C589(3.89); C823(1.18)  LDD0080  [2]
 LDCM0023  KB03 HCT 116 C588(8.04); C592(8.04); C589(8.04); C823(1.23)  LDD0081  [2]
 LDCM0024  KB05 HCT 116 C588(5.85); C592(5.85); C589(5.85); C823(1.48)  LDD0082  [2]
 LDCM0021  THZ1 HCT 116 C201(1.01); C463(1.07); C353(0.86); C588(1.11)  LDD2173  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
TRPM8 channel-associated factor 1 (TCAF1) TCAF family Q9Y4C2

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
4 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
5 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
6 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
7 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
8 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
9 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
10 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
11 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578