Details of the Target

General Information of Target

Target ID LDTP13604
Target Name Hippocalcin-like protein 4 (HPCAL4)
Gene Name HPCAL4
Gene ID 51440
Synonyms
Hippocalcin-like protein 4; HLP4
3D Structure
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2D Sequence (FASTA)
Download
3D Structure (PDB)
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Sequence
MTTPNKTPPGADPKQLERTGTVREIGSQAVWSLSSCKPGFGVDQLRDDNLETYWQSDGSQ
PHLVNIQFRRKTTVKTLCIYADYKSDESYTPSKISVRVGNNFHNLQEIRQLELVEPSGWI
HVPLTDNHKKPTRTFMIQIAVLANHQNGRDTHMRQIKIYTPVEESSIGKFPRCTTIDFMM
YRSIR
Target Bioclass
Other
Family
Recoverin family
Function May be involved in the calcium-dependent regulation of rhodopsin phosphorylation.
Uniprot ID
Q9UM19
Ensemble ID
ENST00000372844.8
HGNC ID
HGNC:18212

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
HPAP
 Probe Info  		3.39  LDD0062  [1]
DBIA
 Probe Info  		C87(0.97)  LDD0532  [2]
IPM
 Probe Info  		C87(0.00); C187(0.00)  LDD2156  [3]
PAL-AfBPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C040
 Probe Info  		6.41  LDD1740  [4]
C353
 Probe Info  		6.02  LDD2014  [4]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C187(0.92); C38(1.05)  LDD1507  [5]
 LDCM0215  AC10 HCT 116 C87(0.97)  LDD0532  [2]
 LDCM0226  AC11 HCT 116 C87(1.07)  LDD0543  [2]
 LDCM0230  AC113 HCT 116 C87(1.06)  LDD0547  [2]
 LDCM0231  AC114 HCT 116 C87(1.65)  LDD0548  [2]
 LDCM0232  AC115 HCT 116 C87(1.23)  LDD0549  [2]
 LDCM0233  AC116 HCT 116 C87(1.18)  LDD0550  [2]
 LDCM0234  AC117 HCT 116 C87(1.39)  LDD0551  [2]
 LDCM0235  AC118 HCT 116 C87(1.04)  LDD0552  [2]
 LDCM0236  AC119 HCT 116 C87(1.09)  LDD0553  [2]
 LDCM0237  AC12 HCT 116 C87(0.76)  LDD0554  [2]
 LDCM0238  AC120 HCT 116 C87(1.40)  LDD0555  [2]
 LDCM0239  AC121 HCT 116 C87(1.16)  LDD0556  [2]
 LDCM0240  AC122 HCT 116 C87(1.27)  LDD0557  [2]
 LDCM0241  AC123 HCT 116 C87(1.41)  LDD0558  [2]
 LDCM0242  AC124 HCT 116 C87(1.30)  LDD0559  [2]
 LDCM0243  AC125 HCT 116 C87(1.23)  LDD0560  [2]
 LDCM0244  AC126 HCT 116 C87(1.32)  LDD0561  [2]
 LDCM0245  AC127 HCT 116 C87(1.35)  LDD0562  [2]
 LDCM0246  AC128 HEK-293T C87(1.14)  LDD0844  [2]
 LDCM0247  AC129 HEK-293T C87(1.09)  LDD0845  [2]
 LDCM0249  AC130 HEK-293T C87(0.72)  LDD0847  [2]
 LDCM0250  AC131 HEK-293T C87(1.00)  LDD0848  [2]
 LDCM0251  AC132 HEK-293T C87(1.04)  LDD0849  [2]
 LDCM0252  AC133 HEK-293T C87(0.97)  LDD0850  [2]
 LDCM0253  AC134 HEK-293T C87(1.07)  LDD0851  [2]
 LDCM0254  AC135 HEK-293T C87(1.15)  LDD0852  [2]
 LDCM0255  AC136 HEK-293T C87(1.09)  LDD0853  [2]
 LDCM0256  AC137 HEK-293T C87(1.12)  LDD0854  [2]
 LDCM0257  AC138 HEK-293T C87(1.03)  LDD0855  [2]
 LDCM0258  AC139 HEK-293T C87(1.09)  LDD0856  [2]
 LDCM0259  AC14 HCT 116 C87(1.00)  LDD0576  [2]
 LDCM0260  AC140 HEK-293T C87(1.53)  LDD0858  [2]
 LDCM0261  AC141 HEK-293T C87(1.27)  LDD0859  [2]
 LDCM0262  AC142 HEK-293T C87(1.08)  LDD0860  [2]
 LDCM0263  AC143 HEK-293T C87(1.18)  LDD0861  [2]
 LDCM0264  AC144 HEK-293T C87(0.99)  LDD0862  [2]
 LDCM0265  AC145 HEK-293T C87(1.24)  LDD0863  [2]
 LDCM0266  AC146 HEK-293T C87(1.18)  LDD0864  [2]
 LDCM0267  AC147 HEK-293T C87(1.14)  LDD0865  [2]
 LDCM0268  AC148 HEK-293T C87(1.14)  LDD0866  [2]
 LDCM0269  AC149 HEK-293T C87(0.96)  LDD0867  [2]
 LDCM0270  AC15 HCT 116 C87(0.82)  LDD0587  [2]
 LDCM0271  AC150 HEK-293T C87(1.13)  LDD0869  [2]
 LDCM0272  AC151 HEK-293T C87(1.24)  LDD0870  [2]
 LDCM0273  AC152 HEK-293T C87(0.88)  LDD0871  [2]
 LDCM0274  AC153 HEK-293T C87(0.93)  LDD0872  [2]
 LDCM0621  AC154 HEK-293T C87(0.96)  LDD2162  [2]
 LDCM0622  AC155 HEK-293T C87(1.07)  LDD2163  [2]
 LDCM0623  AC156 HEK-293T C87(1.14)  LDD2164  [2]
 LDCM0624  AC157 HEK-293T C87(0.88)  LDD2165  [2]
 LDCM0276  AC17 HCT 116 C87(0.96)  LDD0593  [2]
 LDCM0277  AC18 HCT 116 C87(1.18)  LDD0594  [2]
 LDCM0278  AC19 HCT 116 C87(1.29)  LDD0595  [2]
 LDCM0279  AC2 HEK-293T C187(1.01); C87(1.00); C38(0.94)  LDD1518  [5]
 LDCM0280  AC20 HCT 116 C87(1.10)  LDD0597  [2]
 LDCM0281  AC21 HCT 116 C87(0.95)  LDD0598  [2]
 LDCM0282  AC22 HCT 116 C87(1.02)  LDD0599  [2]
 LDCM0283  AC23 HCT 116 C87(1.09)  LDD0600  [2]
 LDCM0284  AC24 HCT 116 C87(1.21)  LDD0601  [2]
 LDCM0285  AC25 HEK-293T C187(1.00); C38(1.08)  LDD1524  [5]
 LDCM0286  AC26 HEK-293T C187(1.19); C87(1.00); C38(1.23)  LDD1525  [5]
 LDCM0287  AC27 HEK-293T C187(1.02); C38(1.14)  LDD1526  [5]
 LDCM0288  AC28 HEK-293T C187(0.95); C87(0.98); C38(1.09)  LDD1527  [5]
 LDCM0289  AC29 HEK-293T C187(1.04); C87(1.08); C38(0.97)  LDD1528  [5]
 LDCM0290  AC3 HEK-293T C187(0.97); C38(1.02)  LDD1529  [5]
 LDCM0291  AC30 HEK-293T C187(0.90); C87(1.06); C38(1.05)  LDD1530  [5]
 LDCM0292  AC31 HEK-293T C187(0.92); C38(1.17)  LDD1531  [5]
 LDCM0293  AC32 HEK-293T C187(0.84); C87(1.00); C38(1.05)  LDD1532  [5]
 LDCM0294  AC33 HEK-293T C187(1.04); C38(1.12)  LDD1533  [5]
 LDCM0295  AC34 HEK-293T C187(1.19); C87(1.04); C38(1.08)  LDD1534  [5]
 LDCM0296  AC35 HCT 116 C87(1.10)  LDD0613  [2]
 LDCM0297  AC36 HCT 116 C87(0.91)  LDD0614  [2]
 LDCM0298  AC37 HCT 116 C87(0.71)  LDD0615  [2]
 LDCM0299  AC38 HCT 116 C87(0.75)  LDD0616  [2]
 LDCM0300  AC39 HCT 116 C87(0.60)  LDD0617  [2]
 LDCM0301  AC4 HEK-293T C187(0.70); C87(0.95); C38(1.09)  LDD1540  [5]
 LDCM0302  AC40 HCT 116 C87(0.56)  LDD0619  [2]
 LDCM0303  AC41 HCT 116 C87(0.69)  LDD0620  [2]
 LDCM0304  AC42 HCT 116 C87(0.64)  LDD0621  [2]
 LDCM0305  AC43 HCT 116 C87(0.61)  LDD0622  [2]
 LDCM0306  AC44 HCT 116 C87(0.60)  LDD0623  [2]
 LDCM0307  AC45 HCT 116 C87(0.56)  LDD0624  [2]
 LDCM0308  AC46 HEK-293T C187(0.99); C87(1.03); C38(1.21)  LDD1547  [5]
 LDCM0309  AC47 HEK-293T C187(0.93); C38(1.04)  LDD1548  [5]
 LDCM0310  AC48 HEK-293T C187(1.01); C87(1.05); C38(1.10)  LDD1549  [5]
 LDCM0311  AC49 HEK-293T C187(1.05); C38(0.87)  LDD1550  [5]
 LDCM0312  AC5 HEK-293T C187(0.94); C87(1.07); C38(0.96)  LDD1551  [5]
 LDCM0313  AC50 HEK-293T C187(1.12); C87(0.94); C38(1.26)  LDD1552  [5]
 LDCM0314  AC51 HEK-293T C187(0.98); C38(1.04)  LDD1553  [5]
 LDCM0315  AC52 HEK-293T C187(0.87); C87(0.88); C38(1.07)  LDD1554  [5]
 LDCM0316  AC53 HEK-293T C187(0.94); C87(1.06); C38(1.01)  LDD1555  [5]
 LDCM0317  AC54 HEK-293T C187(1.01); C87(1.10); C38(1.08)  LDD1556  [5]
 LDCM0318  AC55 HEK-293T C187(0.88); C38(1.17)  LDD1557  [5]
 LDCM0319  AC56 HEK-293T C187(0.89); C87(0.98); C38(1.11)  LDD1558  [5]
 LDCM0320  AC57 HCT 116 C87(0.83)  LDD0637  [2]
 LDCM0321  AC58 HCT 116 C87(0.92)  LDD0638  [2]
 LDCM0322  AC59 HCT 116 C87(0.92)  LDD0639  [2]
 LDCM0323  AC6 HCT 116 C87(0.99)  LDD0640  [2]
 LDCM0324  AC60 HCT 116 C87(0.84)  LDD0641  [2]
 LDCM0325  AC61 HCT 116 C87(0.63)  LDD0642  [2]
 LDCM0326  AC62 HCT 116 C87(0.89)  LDD0643  [2]
 LDCM0327  AC63 HCT 116 C87(0.85)  LDD0644  [2]
 LDCM0328  AC64 HCT 116 C87(1.02)  LDD0645  [2]
 LDCM0329  AC65 HCT 116 C87(0.75)  LDD0646  [2]
 LDCM0330  AC66 HCT 116 C87(1.10)  LDD0647  [2]
 LDCM0331  AC67 HCT 116 C87(0.95)  LDD0648  [2]
 LDCM0332  AC68 HEK-293T C87(1.03)  LDD0930  [2]
 LDCM0333  AC69 HEK-293T C87(0.96)  LDD0931  [2]
 LDCM0334  AC7 HCT 116 C87(0.84)  LDD0651  [2]
 LDCM0335  AC70 HEK-293T C87(1.10)  LDD0933  [2]
 LDCM0336  AC71 HEK-293T C87(1.11)  LDD0934  [2]
 LDCM0337  AC72 HEK-293T C87(1.08)  LDD0935  [2]
 LDCM0338  AC73 HEK-293T C87(1.23)  LDD0936  [2]
 LDCM0339  AC74 HEK-293T C87(0.98)  LDD0937  [2]
 LDCM0340  AC75 HEK-293T C87(1.01)  LDD0938  [2]
 LDCM0341  AC76 HEK-293T C87(0.93)  LDD0939  [2]
 LDCM0342  AC77 HEK-293T C87(0.78)  LDD0940  [2]
 LDCM0343  AC78 HEK-293T C87(1.00)  LDD0941  [2]
 LDCM0344  AC79 HEK-293T C87(1.20)  LDD0942  [2]
 LDCM0345  AC8 HCT 116 C87(0.83)  LDD0662  [2]
 LDCM0346  AC80 HEK-293T C87(1.06)  LDD0944  [2]
 LDCM0347  AC81 HEK-293T C87(0.88)  LDD0945  [2]
 LDCM0348  AC82 HEK-293T C87(0.90)  LDD0946  [2]
 LDCM0349  AC83 HCT 116 C87(1.48)  LDD0666  [2]
 LDCM0350  AC84 HCT 116 C87(1.65)  LDD0667  [2]
 LDCM0351  AC85 HCT 116 C87(1.16)  LDD0668  [2]
 LDCM0352  AC86 HCT 116 C87(1.23)  LDD0669  [2]
 LDCM0353  AC87 HCT 116 C87(1.22)  LDD0670  [2]
 LDCM0354  AC88 HCT 116 C87(1.28)  LDD0671  [2]
 LDCM0355  AC89 HCT 116 C87(1.12)  LDD0672  [2]
 LDCM0357  AC90 HCT 116 C87(1.59)  LDD0674  [2]
 LDCM0358  AC91 HCT 116 C87(1.24)  LDD0675  [2]
 LDCM0359  AC92 HCT 116 C87(1.52)  LDD0676  [2]
 LDCM0360  AC93 HCT 116 C87(1.22)  LDD0677  [2]
 LDCM0361  AC94 HCT 116 C87(1.20)  LDD0678  [2]
 LDCM0362  AC95 HCT 116 C87(1.55)  LDD0679  [2]
 LDCM0363  AC96 HCT 116 C87(1.01)  LDD0680  [2]
 LDCM0364  AC97 HCT 116 C87(1.34)  LDD0681  [2]
 LDCM0248  AKOS034007472 HCT 116 C87(0.82)  LDD0565  [2]
 LDCM0356  AKOS034007680 HCT 116 C87(1.10)  LDD0673  [2]
 LDCM0275  AKOS034007705 HCT 116 C87(0.77)  LDD0592  [2]
 LDCM0367  CL1 HCT 116 C87(0.70)  LDD0684  [2]
 LDCM0368  CL10 HCT 116 C87(0.67)  LDD0685  [2]
 LDCM0369  CL100 HEK-293T C187(1.12); C87(0.96); C38(0.94)  LDD1573  [5]
 LDCM0370  CL101 HCT 116 C87(0.97)  LDD0687  [2]
 LDCM0371  CL102 HCT 116 C87(0.95)  LDD0688  [2]
 LDCM0372  CL103 HCT 116 C87(0.93)  LDD0689  [2]
 LDCM0373  CL104 HCT 116 C87(0.87)  LDD0690  [2]
 LDCM0374  CL105 HCT 116 C87(1.26)  LDD0691  [2]
 LDCM0375  CL106 HCT 116 C87(1.25)  LDD0692  [2]
 LDCM0376  CL107 HCT 116 C87(1.29)  LDD0693  [2]
 LDCM0377  CL108 HCT 116 C87(0.97)  LDD0694  [2]
 LDCM0378  CL109 HCT 116 C87(1.30)  LDD0695  [2]
 LDCM0379  CL11 HCT 116 C87(0.62)  LDD0696  [2]
 LDCM0380  CL110 HCT 116 C87(0.93)  LDD0697  [2]
 LDCM0381  CL111 HCT 116 C87(1.03)  LDD0698  [2]
 LDCM0382  CL112 HEK-293T C187(1.09); C87(1.02); C38(0.80)  LDD1586  [5]
 LDCM0383  CL113 HEK-293T C187(0.88); C87(1.05); C38(1.12)  LDD1587  [5]
 LDCM0384  CL114 HEK-293T C187(2.47); C38(0.89)  LDD1588  [5]
 LDCM0385  CL115 HEK-293T C187(0.99); C87(0.98); C38(1.26)  LDD1589  [5]
 LDCM0386  CL116 HEK-293T C187(0.92); C87(0.95); C38(0.87)  LDD1590  [5]
 LDCM0387  CL117 HCT 116 C87(0.41)  LDD0704  [2]
 LDCM0388  CL118 HCT 116 C87(1.12)  LDD0705  [2]
 LDCM0389  CL119 HCT 116 C87(0.98)  LDD0706  [2]
 LDCM0390  CL12 HCT 116 C87(0.81)  LDD0707  [2]
 LDCM0391  CL120 HCT 116 C87(0.86)  LDD0708  [2]
 LDCM0392  CL121 HEK-293T C187(1.10); C87(1.15); C38(1.13)  LDD1596  [5]
 LDCM0393  CL122 HEK-293T C187(1.00); C38(1.12)  LDD1597  [5]
 LDCM0394  CL123 HEK-293T C187(1.25); C87(0.94); C38(0.84)  LDD1598  [5]
 LDCM0395  CL124 HEK-293T C187(1.99); C87(1.06); C38(0.84)  LDD1599  [5]
 LDCM0396  CL125 HCT 116 C87(1.07)  LDD0713  [2]
 LDCM0397  CL126 HCT 116 C87(0.93)  LDD0714  [2]
 LDCM0398  CL127 HCT 116 C87(0.81)  LDD0715  [2]
 LDCM0399  CL128 HCT 116 C87(0.85)  LDD0716  [2]
 LDCM0400  CL13 HCT 116 C87(0.82)  LDD0717  [2]
 LDCM0401  CL14 HCT 116 C87(1.00)  LDD0718  [2]
 LDCM0402  CL15 HCT 116 C87(0.99)  LDD0719  [2]
 LDCM0403  CL16 HCT 116 C87(0.93)  LDD0720  [2]
 LDCM0404  CL17 HCT 116 C87(0.71)  LDD0721  [2]
 LDCM0405  CL18 HCT 116 C87(0.68)  LDD0722  [2]
 LDCM0406  CL19 HCT 116 C87(0.86)  LDD0723  [2]
 LDCM0407  CL2 HCT 116 C87(0.91)  LDD0724  [2]
 LDCM0408  CL20 HCT 116 C87(0.73)  LDD0725  [2]
 LDCM0409  CL21 HCT 116 C87(0.62)  LDD0726  [2]
 LDCM0410  CL22 HCT 116 C87(0.96)  LDD0727  [2]
 LDCM0411  CL23 HCT 116 C87(0.91)  LDD0728  [2]
 LDCM0412  CL24 HCT 116 C87(0.74)  LDD0729  [2]
 LDCM0413  CL25 HCT 116 C87(0.70)  LDD0730  [2]
 LDCM0414  CL26 HCT 116 C87(0.81)  LDD0731  [2]
 LDCM0415  CL27 HCT 116 C87(0.72)  LDD0732  [2]
 LDCM0416  CL28 HCT 116 C87(0.84)  LDD0733  [2]
 LDCM0417  CL29 HCT 116 C87(0.71)  LDD0734  [2]
 LDCM0418  CL3 HCT 116 C87(0.79)  LDD0735  [2]
 LDCM0419  CL30 HCT 116 C87(0.75)  LDD0736  [2]
 LDCM0420  CL31 HEK-293T C187(1.02); C38(1.09)  LDD1624  [5]
 LDCM0421  CL32 HCT 116 C87(0.92)  LDD0738  [2]
 LDCM0422  CL33 HCT 116 C87(0.91)  LDD0739  [2]
 LDCM0423  CL34 HCT 116 C87(0.91)  LDD0740  [2]
 LDCM0424  CL35 HCT 116 C87(0.88)  LDD0741  [2]
 LDCM0425  CL36 HCT 116 C87(0.83)  LDD0742  [2]
 LDCM0426  CL37 HCT 116 C87(0.96)  LDD0743  [2]
 LDCM0428  CL39 HCT 116 C87(1.03)  LDD0745  [2]
 LDCM0429  CL4 HCT 116 C87(1.09)  LDD0746  [2]
 LDCM0430  CL40 HCT 116 C87(0.92)  LDD0747  [2]
 LDCM0431  CL41 HCT 116 C87(0.88)  LDD0748  [2]
 LDCM0432  CL42 HCT 116 C87(0.97)  LDD0749  [2]
 LDCM0433  CL43 HCT 116 C87(0.89)  LDD0750  [2]
 LDCM0434  CL44 HCT 116 C87(0.94)  LDD0751  [2]
 LDCM0435  CL45 HCT 116 C87(0.83)  LDD0752  [2]
 LDCM0436  CL46 HCT 116 C87(0.79)  LDD0753  [2]
 LDCM0437  CL47 HCT 116 C87(0.96)  LDD0754  [2]
 LDCM0438  CL48 HCT 116 C87(0.77)  LDD0755  [2]
 LDCM0439  CL49 HCT 116 C87(0.85)  LDD0756  [2]
 LDCM0440  CL5 HCT 116 C87(1.02)  LDD0757  [2]
 LDCM0441  CL50 HCT 116 C87(0.85)  LDD0758  [2]
 LDCM0442  CL51 HCT 116 C87(0.78)  LDD0759  [2]
 LDCM0443  CL52 HCT 116 C87(0.88)  LDD0760  [2]
 LDCM0444  CL53 HCT 116 C87(1.33)  LDD0761  [2]
 LDCM0445  CL54 HCT 116 C87(0.84)  LDD0762  [2]
 LDCM0446  CL55 HCT 116 C87(0.97)  LDD0763  [2]
 LDCM0447  CL56 HCT 116 C87(0.93)  LDD0764  [2]
 LDCM0448  CL57 HCT 116 C87(0.97)  LDD0765  [2]
 LDCM0449  CL58 HCT 116 C87(0.91)  LDD0766  [2]
 LDCM0450  CL59 HCT 116 C87(0.90)  LDD0767  [2]
 LDCM0451  CL6 HCT 116 C87(0.76)  LDD0768  [2]
 LDCM0452  CL60 HCT 116 C87(0.72)  LDD0769  [2]
 LDCM0453  CL61 HEK-293T C187(0.83); C87(0.97); C38(1.11)  LDD1656  [5]
 LDCM0454  CL62 HEK-293T C187(1.07); C38(1.10)  LDD1657  [5]
 LDCM0455  CL63 HEK-293T C187(0.96); C87(1.02); C38(0.87)  LDD1658  [5]
 LDCM0456  CL64 HEK-293T C187(1.92); C87(0.97); C38(0.73)  LDD1659  [5]
 LDCM0457  CL65 HEK-293T C187(1.02); C38(1.36)  LDD1660  [5]
 LDCM0458  CL66 HEK-293T C187(1.24); C87(0.98); C38(1.04)  LDD1661  [5]
 LDCM0459  CL67 HEK-293T C187(1.01); C38(1.26)  LDD1662  [5]
 LDCM0460  CL68 HEK-293T C187(1.04); C87(1.15); C38(1.07)  LDD1663  [5]
 LDCM0461  CL69 HEK-293T C187(1.19); C87(1.29); C38(0.98)  LDD1664  [5]
 LDCM0462  CL7 HCT 116 C87(0.80)  LDD0779  [2]
 LDCM0463  CL70 HEK-293T C187(0.96); C87(1.15); C38(1.09)  LDD1666  [5]
 LDCM0464  CL71 HEK-293T C187(1.17); C38(1.12)  LDD1667  [5]
 LDCM0465  CL72 HEK-293T C187(0.91); C87(1.28); C38(0.83)  LDD1668  [5]
 LDCM0466  CL73 HEK-293T C187(1.38); C87(0.95); C38(1.02)  LDD1669  [5]
 LDCM0467  CL74 HEK-293T C187(1.03); C38(0.98)  LDD1670  [5]
 LDCM0469  CL76 HEK-293T C187(1.18); C87(1.21); C38(0.92)  LDD1672  [5]
 LDCM0470  CL77 HEK-293T C187(1.74); C38(0.89)  LDD1673  [5]
 LDCM0471  CL78 HEK-293T C187(1.10); C87(0.95); C38(1.08)  LDD1674  [5]
 LDCM0472  CL79 HEK-293T C187(1.00); C38(1.06)  LDD1675  [5]
 LDCM0473  CL8 HCT 116 C87(0.75)  LDD0790  [2]
 LDCM0474  CL80 HEK-293T C187(0.96); C87(1.09); C38(1.16)  LDD1677  [5]
 LDCM0475  CL81 HEK-293T C187(0.94); C87(1.20); C38(0.99)  LDD1678  [5]
 LDCM0476  CL82 HEK-293T C187(0.86); C87(1.17); C38(1.04)  LDD1679  [5]
 LDCM0477  CL83 HEK-293T C187(1.18); C38(0.87)  LDD1680  [5]
 LDCM0478  CL84 HEK-293T C187(1.68); C87(1.20); C38(0.80)  LDD1681  [5]
 LDCM0479  CL85 HEK-293T C187(0.83); C87(1.03); C38(1.10)  LDD1682  [5]
 LDCM0480  CL86 HEK-293T C187(1.19); C38(1.03)  LDD1683  [5]
 LDCM0481  CL87 HEK-293T C187(0.97); C87(0.86); C38(1.05)  LDD1684  [5]
 LDCM0482  CL88 HEK-293T C187(1.10); C87(0.97); C38(0.80)  LDD1685  [5]
 LDCM0483  CL89 HEK-293T C187(1.11); C38(1.10)  LDD1686  [5]
 LDCM0484  CL9 HCT 116 C87(0.93)  LDD0801  [2]
 LDCM0485  CL90 HEK-293T C187(1.85); C87(0.99); C38(0.87)  LDD1688  [5]
 LDCM0486  CL91 HEK-293T C187(0.94); C38(0.98)  LDD1689  [5]
 LDCM0487  CL92 HEK-293T C187(0.88); C87(0.93); C38(0.98)  LDD1690  [5]
 LDCM0488  CL93 HEK-293T C187(1.07); C87(1.23); C38(1.01)  LDD1691  [5]
 LDCM0489  CL94 HEK-293T C187(0.96); C87(1.24); C38(0.96)  LDD1692  [5]
 LDCM0490  CL95 HEK-293T C187(3.00); C38(0.74)  LDD1693  [5]
 LDCM0491  CL96 HEK-293T C187(1.82); C87(1.12); C38(0.86)  LDD1694  [5]
 LDCM0492  CL97 HEK-293T C187(1.58); C87(1.02); C38(0.92)  LDD1695  [5]
 LDCM0493  CL98 HEK-293T C187(1.14); C38(0.98)  LDD1696  [5]
 LDCM0494  CL99 HEK-293T C187(1.06); C87(0.98); C38(1.09)  LDD1697  [5]
 LDCM0495  E2913 HEK-293T C187(0.96); C87(0.94); C38(1.58)  LDD1698  [5]
 LDCM0468  Fragment33 HEK-293T C187(0.97); C87(0.98); C38(1.06)  LDD1671  [5]
 LDCM0427  Fragment51 HCT 116 C87(1.03)  LDD0744  [2]
 LDCM0022  KB02 HEK-293T C87(0.90); C38(1.04)  LDD1492  [5]
 LDCM0023  KB03 HEK-293T C87(1.06); C38(1.11)  LDD1497  [5]
 LDCM0024  KB05 NB1 C87(2.47)  LDD3340  [6]
 LDCM0014  Panhematin HEK-293T 3.39  LDD0062  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Probable E3 ubiquitin-protein ligase DTX2 (DTX2) Deltex family Q86UW9
Mitochondrial peptide methionine sulfoxide reductase (MSRA) MsrA Met sulfoxide reductase family Q9UJ68
Transporter and channel
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Aquaporin-4 (AQP4) MIP/aquaporin (TC 1.A.8) family P55087
Tissue factor (F3) Tissue factor family P13726
Transient receptor potential cation channel subfamily M member 5 (TRPM5) Transient receptor (TC 1.A.4) family Q9NZQ8
Immunoglobulin
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) CEA family P40199
Other
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Lipopolysaccharide-induced tumor necrosis factor-alpha factor (LITAF) CDIP1/LITAF family Q99732
Protein FAM131C (FAM131C) FAM131 family Q96AQ9
Polycomb protein SCMH1 (SCMH1) SCM family Q96GD3
Testis-expressed protein 13B (TEX13B) TEX13 family Q9BXU2
Sprouty-related, EVH1 domain-containing protein 1 (SPRED1) . Q7Z699

References

1 A Chemical Proteomic Map of Heme-Protein Interactions. J Am Chem Soc. 2022 Aug 24;144(33):15013-15019. doi: 10.1021/jacs.2c06104. Epub 2022 Aug 12.
Mass spectrometry data entry: PXD034651
2 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
3 Benchmarking Cleavable Biotin Tags for Peptide-Centric Chemoproteomics. J Proteome Res. 2022 May 6;21(5):1349-1358. doi: 10.1021/acs.jproteome.2c00174. Epub 2022 Apr 25.
Mass spectrometry data entry: PXD031019
4 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
5 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
6 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840