Details of the Target

General Information of Target

Target ID LDTP11947
Target Name Zinc finger protein 644 (ZNF644)
Gene Name ZNF644
Gene ID 84146
Synonyms
KIAA1221; ZEP2; Zinc finger protein 644; Zinc finger motif enhancer-binding protein 2; Zep-2
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAEEQGRERDSVPKPSVLFLHPDLGVGGAERLVLDAALALQARGCSVKIWTAHYDPGHCF
AESRELPVRCAGDWLPRGLGWGGRGAAVCAYVRMVFLALYVLFLADEEFDVVVCDQVSAC
IPVFRLARRRKKILFYCHFPDLLLTKRDSFLKRLYRAPIDWIEEYTTGMADCILVNSQFT
AAVFKETFKSLSHIDPDVLYPSLNVTSFDSVVPEKLDDLVPKGKKFLLLSINRYERKKNL
TLALEALVQLRGRLTSQDWERVHLIVAGGYDERVLENVEHYQELKKMVQQSDLGQYVTFL
RSFSDKQKISLLHSCTCVLYTPSNEHFGIVPLEAMYMQCPVIAVNSGGPLESIDHSVTGF
LCEPDPVHFSEAIEKFIREPSLKATMGLAGRARVKEKFSPEAFTEQLYRYVTKLLV
Target Bioclass
Transcription factor
Family
Krueppel C2H2-type zinc-finger protein family
Subcellular location
Nucleus
Function May be involved in transcriptional regulation.
Uniprot ID
Q9H582
Ensemble ID
ENST00000337393.10
HGNC ID
HGNC:29222

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
CORL88 SNV: p.A169S DBIA    Probe Info 
HEC1 SNV: p.A944D DBIA    Probe Info 
HEC1B SNV: p.G247D .
ICC3 SNV: p.N913S DBIA    Probe Info 
Ishikawa (Heraklio) 02 ER SNV: p.P367T DBIA    Probe Info 
JHH7 SNV: p.L643F .
KMCH1 Deletion: p.Y921_N927del
SNV: p.R420W		 DBIA    Probe Info 
MOLT4 SNV: p.R440H .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 11 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		14.57  LDD0402  [1]
AHL-Pu-1
 Probe Info  		C307(2.36)  LDD0168  [2]
DBIA
 Probe Info  		C307(0.97); C313(0.97)  LDD0078  [3]
IA-alkyne
 Probe Info  		C202(0.00); C1077(0.00); C554(0.00)  LDD0165  [4]
NAIA_4
 Probe Info  		C152(0.00); C202(0.00); C613(0.00)  LDD2226  [5]
NAIA_5
 Probe Info  		N.A.  LDD2224  [5]
IPM
 Probe Info  		N.A.  LDD0005  [6]
TFBX
 Probe Info  		C415(0.00); C554(0.00)  LDD0148  [7]
VSF
 Probe Info  		C202(0.00); C152(0.00)  LDD0007  [6]
Phosphinate-6
 Probe Info  		C202(0.00); C613(0.00); C507(0.00)  LDD0018  [8]
AOyne
 Probe Info  		10.30  LDD0443  [9]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA HEK-293T C307(2.36)  LDD0168  [2]
 LDCM0026  4SU-RNA+native RNA HEK-293T C307(6.45)  LDD0169  [2]
 LDCM0214  AC1 HCT 116 C507(0.73); C152(1.30); C391(1.09); C412(1.09)  LDD0531  [3]
 LDCM0215  AC10 HCT 116 C507(0.67); C498(0.67); C152(1.18); C307(1.04)  LDD0532  [3]
 LDCM0216  AC100 HCT 116 C507(1.10); C237(0.71); C307(0.96); C313(0.89)  LDD0533  [3]
 LDCM0217  AC101 HCT 116 C507(1.30); C237(0.70); C307(1.00); C313(1.02)  LDD0534  [3]
 LDCM0218  AC102 HCT 116 C507(1.06); C237(0.73); C307(0.99); C313(1.02)  LDD0535  [3]
 LDCM0219  AC103 HCT 116 C507(1.36); C237(0.72); C307(1.53); C313(1.36)  LDD0536  [3]
 LDCM0220  AC104 HCT 116 C507(0.97); C237(0.85); C307(1.21); C313(1.17)  LDD0537  [3]
 LDCM0221  AC105 HCT 116 C507(1.42); C237(0.87); C307(1.19); C313(1.12)  LDD0538  [3]
 LDCM0222  AC106 HCT 116 C507(1.29); C237(0.82); C307(1.22); C313(1.17)  LDD0539  [3]
 LDCM0223  AC107 HCT 116 C507(1.43); C237(0.81); C307(1.31); C313(1.17)  LDD0540  [3]
 LDCM0224  AC108 HCT 116 C507(1.10); C237(0.90); C307(0.78); C313(0.77)  LDD0541  [3]
 LDCM0225  AC109 HCT 116 C507(0.96); C237(0.74); C307(0.85); C313(0.82)  LDD0542  [3]
 LDCM0226  AC11 HCT 116 C507(0.90); C498(0.90); C152(1.12); C307(1.49)  LDD0543  [3]
 LDCM0227  AC110 HCT 116 C507(1.05); C237(0.87); C307(0.92); C313(0.84)  LDD0544  [3]
 LDCM0228  AC111 HCT 116 C507(1.01); C237(0.84); C307(1.02); C313(0.98)  LDD0545  [3]
 LDCM0229  AC112 HCT 116 C507(1.15); C237(0.91); C307(1.25); C313(1.12)  LDD0546  [3]
 LDCM0230  AC113 HCT 116 C507(0.97); C307(1.02); C313(1.02); C554(0.93)  LDD0547  [3]
 LDCM0231  AC114 HCT 116 C507(0.98); C307(1.18); C313(1.17); C554(0.96)  LDD0548  [3]
 LDCM0232  AC115 HCT 116 C507(1.05); C307(1.39); C313(1.43); C554(0.83)  LDD0549  [3]
 LDCM0233  AC116 HCT 116 C507(1.09); C307(1.31); C313(1.24); C554(0.71)  LDD0550  [3]
 LDCM0234  AC117 HCT 116 C507(1.09); C307(1.01); C313(1.07); C554(0.83)  LDD0551  [3]
 LDCM0235  AC118 HCT 116 C507(0.97); C307(1.10); C313(0.96); C554(0.90)  LDD0552  [3]
 LDCM0236  AC119 HCT 116 C507(1.02); C307(1.20); C313(1.19); C554(0.82)  LDD0553  [3]
 LDCM0237  AC12 HCT 116 C507(0.93); C498(0.93); C152(0.95); C307(1.14)  LDD0554  [3]
 LDCM0238  AC120 HCT 116 C507(1.16); C307(1.35); C313(1.25); C554(0.91)  LDD0555  [3]
 LDCM0239  AC121 HCT 116 C507(0.97); C307(0.92); C313(1.02); C554(0.92)  LDD0556  [3]
 LDCM0240  AC122 HCT 116 C507(0.93); C307(1.00); C313(1.16); C554(0.89)  LDD0557  [3]
 LDCM0241  AC123 HCT 116 C507(1.02); C307(0.85); C313(1.06); C554(0.75)  LDD0558  [3]
 LDCM0242  AC124 HCT 116 C507(0.91); C307(1.31); C313(1.21); C554(0.90)  LDD0559  [3]
 LDCM0243  AC125 HCT 116 C507(1.04); C307(1.23); C313(1.20); C554(0.93)  LDD0560  [3]
 LDCM0244  AC126 HCT 116 C507(1.05); C307(1.52); C313(1.57); C554(0.88)  LDD0561  [3]
 LDCM0245  AC127 HCT 116 C507(1.15); C307(1.27); C313(1.27); C554(0.91)  LDD0562  [3]
 LDCM0246  AC128 HCT 116 C507(0.79); C307(0.60); C313(0.60); C588(0.57)  LDD0563  [3]
 LDCM0247  AC129 HCT 116 C507(0.81); C307(0.44); C313(0.44); C588(0.62)  LDD0564  [3]
 LDCM0249  AC130 HCT 116 C507(0.94); C307(0.54); C313(0.54); C588(0.63)  LDD0566  [3]
 LDCM0250  AC131 HCT 116 C507(0.82); C307(0.63); C313(0.63); C588(0.57)  LDD0567  [3]
 LDCM0251  AC132 HCT 116 C507(0.95); C307(0.34); C313(0.34); C588(0.71)  LDD0568  [3]
 LDCM0252  AC133 HCT 116 C507(0.88); C307(0.36); C313(0.36); C588(0.85)  LDD0569  [3]
 LDCM0253  AC134 HCT 116 C507(1.09); C307(0.38); C313(0.38); C588(0.76)  LDD0570  [3]
 LDCM0254  AC135 HCT 116 C507(0.78); C307(0.36); C313(0.36); C588(0.70)  LDD0571  [3]
 LDCM0255  AC136 HCT 116 C507(0.96); C307(0.43); C313(0.43); C588(0.79)  LDD0572  [3]
 LDCM0256  AC137 HCT 116 C507(0.91); C307(0.32); C313(0.32); C588(0.61)  LDD0573  [3]
 LDCM0257  AC138 HCT 116 C507(1.15); C307(0.34); C313(0.34); C588(0.82)  LDD0574  [3]
 LDCM0258  AC139 HCT 116 C507(1.19); C307(0.36); C313(0.36); C588(0.84)  LDD0575  [3]
 LDCM0259  AC14 HCT 116 C507(0.85); C498(0.85); C152(1.27); C307(1.07)  LDD0576  [3]
 LDCM0260  AC140 HCT 116 C507(1.24); C307(0.35); C313(0.35); C588(0.89)  LDD0577  [3]
 LDCM0261  AC141 HCT 116 C507(1.25); C307(0.31); C313(0.31); C588(0.95)  LDD0578  [3]
 LDCM0262  AC142 HCT 116 C507(0.90); C307(0.30); C313(0.30); C588(0.90)  LDD0579  [3]
 LDCM0263  AC143 HCT 116 C507(1.01); C498(1.03); C391(0.82); C412(0.82)  LDD0580  [3]
 LDCM0264  AC144 HCT 116 C391(0.73); C412(0.73); C498(0.84); C507(0.86)  LDD0581  [3]
 LDCM0265  AC145 HCT 116 C588(0.82); C307(1.03); C313(1.06); C507(1.10)  LDD0582  [3]
 LDCM0266  AC146 HCT 116 C588(0.76); C498(0.84); C391(0.91); C412(0.91)  LDD0583  [3]
 LDCM0267  AC147 HCT 116 C391(0.71); C412(0.71); C588(0.75); C507(1.07)  LDD0584  [3]
 LDCM0268  AC148 HCT 116 C588(0.73); C391(0.81); C412(0.81); C498(0.97)  LDD0585  [3]
 LDCM0269  AC149 HCT 116 C588(0.67); C391(0.83); C412(0.83); C498(1.03)  LDD0586  [3]
 LDCM0270  AC15 HCT 116 C554(0.88); C307(0.92); C313(0.92); C507(0.95)  LDD0587  [3]
 LDCM0271  AC150 HCT 116 C391(0.71); C412(0.71); C498(0.88); C588(0.90)  LDD0588  [3]
 LDCM0272  AC151 HCT 116 C507(0.81); C498(0.82); C391(1.15); C412(1.15)  LDD0589  [3]
 LDCM0273  AC152 HCT 116 C588(0.41); C391(0.89); C412(0.89); C507(0.99)  LDD0590  [3]
 LDCM0274  AC153 HCT 116 C391(0.66); C412(0.66); C507(0.82); C588(0.86)  LDD0591  [3]
 LDCM0621  AC154 HCT 116 C507(0.85); C498(0.89); C307(1.57); C313(1.57)  LDD2158  [3]
 LDCM0622  AC155 HCT 116 C507(0.87); C498(0.87); C307(1.92); C313(2.12)  LDD2159  [3]
 LDCM0623  AC156 HCT 116 C507(1.03); C498(0.93); C307(1.40); C313(1.46)  LDD2160  [3]
 LDCM0624  AC157 HCT 116 C507(0.92); C498(0.98); C307(1.68); C313(1.86)  LDD2161  [3]
 LDCM0276  AC17 HCT 116 C307(0.35); C391(0.47); C412(0.47); C507(0.97)  LDD0593  [3]
 LDCM0277  AC18 HCT 116 C307(0.44); C391(0.64); C412(0.64); C202(0.93)  LDD0594  [3]
 LDCM0278  AC19 HCT 116 C307(0.36); C391(0.56); C412(0.56); C498(0.96)  LDD0595  [3]
 LDCM0279  AC2 HCT 116 C554(0.76); C391(0.98); C412(0.98); C588(1.08)  LDD0596  [3]
 LDCM0280  AC20 HCT 116 C307(0.37); C391(0.38); C412(0.38); C498(0.77)  LDD0597  [3]
 LDCM0281  AC21 HCT 116 C307(0.37); C391(0.39); C412(0.39); C498(0.68)  LDD0598  [3]
 LDCM0282  AC22 HCT 116 C307(0.37); C391(0.49); C412(0.49); C498(0.76)  LDD0599  [3]
 LDCM0283  AC23 HCT 116 C307(0.36); C391(0.40); C412(0.40); C498(0.67)  LDD0600  [3]
 LDCM0284  AC24 HCT 116 C307(0.29); C391(0.44); C412(0.44); C498(0.71)  LDD0601  [3]
 LDCM0285  AC25 HCT 116 C507(0.70); C588(0.78); C554(1.08); C152(1.23)  LDD0602  [3]
 LDCM0286  AC26 HCT 116 C507(0.99); C588(1.11); C554(1.12); C152(1.58)  LDD0603  [3]
 LDCM0287  AC27 HCT 116 C507(0.77); C588(1.08); C554(1.11); C152(1.44)  LDD0604  [3]
 LDCM0288  AC28 HCT 116 C507(0.85); C588(1.13); C554(1.28); C152(1.86)  LDD0605  [3]
 LDCM0289  AC29 HCT 116 C554(1.19); C588(1.23); C152(1.31); C507(1.36)  LDD0606  [3]
 LDCM0290  AC3 HCT 116 C507(0.71); C554(0.94); C391(1.02); C412(1.02)  LDD0607  [3]
 LDCM0291  AC30 HCT 116 C588(0.81); C554(1.14); C507(1.14); C152(1.32)  LDD0608  [3]
 LDCM0292  AC31 HCT 116 C507(0.90); C554(1.02); C588(1.05); C152(1.51)  LDD0609  [3]
 LDCM0293  AC32 HCT 116 C588(1.13); C507(1.27); C554(1.41); C152(1.74)  LDD0610  [3]
 LDCM0294  AC33 HCT 116 C507(0.97); C588(1.16); C554(1.28); C152(1.74)  LDD0611  [3]
 LDCM0295  AC34 HCT 116 C588(0.97); C507(1.16); C554(1.37); C152(1.69)  LDD0612  [3]
 LDCM0296  AC35 HCT 116 C152(0.64); C554(1.00); C237(1.07)  LDD0613  [3]
 LDCM0297  AC36 HCT 116 C152(1.03); C554(1.30); C237(1.34)  LDD0614  [3]
 LDCM0298  AC37 HCT 116 C152(0.72); C237(0.96); C554(1.32)  LDD0615  [3]
 LDCM0299  AC38 HCT 116 C152(0.94); C554(1.28); C237(1.45)  LDD0616  [3]
 LDCM0300  AC39 HCT 116 C152(0.96); C554(1.23); C237(1.27)  LDD0617  [3]
 LDCM0301  AC4 HCT 116 C507(0.63); C554(0.90); C391(0.96); C412(0.96)  LDD0618  [3]
 LDCM0302  AC40 HCT 116 C152(0.75); C237(1.13); C554(1.66)  LDD0619  [3]
 LDCM0303  AC41 HCT 116 C152(0.71); C237(1.40); C554(1.85)  LDD0620  [3]
 LDCM0304  AC42 HCT 116 C152(1.00); C554(1.25); C237(1.43)  LDD0621  [3]
 LDCM0305  AC43 HCT 116 C152(1.09); C237(1.46); C554(1.56)  LDD0622  [3]
 LDCM0306  AC44 HCT 116 C152(0.83); C237(1.06); C554(1.54)  LDD0623  [3]
 LDCM0307  AC45 HCT 116 C152(1.01); C237(1.12); C554(1.52)  LDD0624  [3]
 LDCM0308  AC46 HCT 116 C237(1.24)  LDD0625  [3]
 LDCM0309  AC47 HCT 116 C237(1.08)  LDD0626  [3]
 LDCM0310  AC48 HCT 116 C237(1.13)  LDD0627  [3]
 LDCM0311  AC49 HCT 116 C237(1.14)  LDD0628  [3]
 LDCM0312  AC5 HCT 116 C507(0.60); C554(0.96); C391(0.97); C412(0.97)  LDD0629  [3]
 LDCM0313  AC50 HCT 116 C237(0.94)  LDD0630  [3]
 LDCM0314  AC51 HCT 116 C237(1.01)  LDD0631  [3]
 LDCM0315  AC52 HCT 116 C237(1.17)  LDD0632  [3]
 LDCM0316  AC53 HCT 116 C237(1.02)  LDD0633  [3]
 LDCM0317  AC54 HCT 116 C237(0.88)  LDD0634  [3]
 LDCM0318  AC55 HCT 116 C237(1.33)  LDD0635  [3]
 LDCM0319  AC56 HCT 116 C237(1.10)  LDD0636  [3]
 LDCM0320  AC57 HCT 116 C507(0.79); C152(1.11)  LDD0637  [3]
 LDCM0321  AC58 HCT 116 C152(1.08); C507(1.47)  LDD0638  [3]
 LDCM0322  AC59 HCT 116 C507(1.19); C152(1.34)  LDD0639  [3]
 LDCM0323  AC6 HCT 116 C507(0.86); C498(0.86); C554(0.87); C307(0.94)  LDD0640  [3]
 LDCM0324  AC60 HCT 116 C507(1.74); C152(1.82)  LDD0641  [3]
 LDCM0325  AC61 HCT 116 C507(0.85); C152(0.92)  LDD0642  [3]
 LDCM0326  AC62 HCT 116 C507(1.23); C152(1.41)  LDD0643  [3]
 LDCM0327  AC63 HCT 116 C152(1.50); C507(1.76)  LDD0644  [3]
 LDCM0328  AC64 HCT 116 C152(0.99); C507(1.42)  LDD0645  [3]
 LDCM0329  AC65 HCT 116 C152(1.04); C507(1.27)  LDD0646  [3]
 LDCM0330  AC66 HCT 116 C507(1.34); C152(1.36)  LDD0647  [3]
 LDCM0331  AC67 HCT 116 C152(1.17); C507(1.33)  LDD0648  [3]
 LDCM0332  AC68 HCT 116 C307(0.74); C313(0.74); C554(1.34); C507(1.42)  LDD0649  [3]
 LDCM0333  AC69 HCT 116 C307(0.83); C313(0.83); C507(1.00); C554(1.24)  LDD0650  [3]
 LDCM0334  AC7 HCT 116 C507(0.75); C498(0.75); C554(1.03); C152(1.04)  LDD0651  [3]
 LDCM0335  AC70 HCT 116 C307(0.65); C313(0.65); C554(1.27); C507(1.63)  LDD0652  [3]
 LDCM0336  AC71 HCT 116 C307(0.54); C313(0.54); C507(1.14); C554(1.67)  LDD0653  [3]
 LDCM0337  AC72 HCT 116 C307(1.03); C313(1.03); C554(1.26); C507(1.39)  LDD0654  [3]
 LDCM0338  AC73 HCT 116 C507(1.43); C307(1.35); C313(1.35); C554(1.79)  LDD0655  [3]
 LDCM0339  AC74 HCT 116 C307(1.01); C313(1.01); C507(1.41); C554(1.56)  LDD0656  [3]
 LDCM0340  AC75 HCT 116 C507(1.28); C307(2.00); C313(2.00); C554(2.22)  LDD0657  [3]
 LDCM0341  AC76 HCT 116 C307(0.87); C313(0.87); C507(1.01); C554(1.58)  LDD0658  [3]
 LDCM0342  AC77 HCT 116 C307(1.21); C313(1.21); C507(1.68); C554(1.95)  LDD0659  [3]
 LDCM0343  AC78 HCT 116 C307(0.78); C313(0.78); C507(1.14); C554(1.25)  LDD0660  [3]
 LDCM0344  AC79 HCT 116 C307(0.69); C313(0.69); C507(1.44); C554(1.44)  LDD0661  [3]
 LDCM0345  AC8 HCT 116 C507(0.74); C498(0.74); C554(0.87); C307(0.94)  LDD0662  [3]
 LDCM0346  AC80 HCT 116 C507(0.87); C307(1.00); C313(1.00); C554(1.36)  LDD0663  [3]
 LDCM0347  AC81 HCT 116 C307(0.74); C313(0.74); C554(0.82); C507(1.14)  LDD0664  [3]
 LDCM0348  AC82 HCT 116 C507(1.18); C307(1.23); C313(1.23); C554(1.70)  LDD0665  [3]
 LDCM0349  AC83 HCT 116 C202(0.75); C237(0.84); C498(1.16); C507(1.17)  LDD0666  [3]
 LDCM0350  AC84 HCT 116 C202(0.70); C237(0.91); C313(1.01); C307(1.02)  LDD0667  [3]
 LDCM0351  AC85 HCT 116 C498(0.79); C313(0.85); C307(0.88); C202(0.95)  LDD0668  [3]
 LDCM0352  AC86 HCT 116 C202(0.78); C507(1.09); C307(1.09); C313(1.11)  LDD0669  [3]
 LDCM0353  AC87 HCT 116 C202(0.73); C498(0.95); C507(0.96); C307(1.01)  LDD0670  [3]
 LDCM0354  AC88 HCT 116 C202(0.82); C498(0.89); C237(1.01); C507(1.11)  LDD0671  [3]
 LDCM0355  AC89 HCT 116 C202(0.81); C237(0.93); C498(0.95); C507(1.02)  LDD0672  [3]
 LDCM0357  AC90 HCT 116 C202(0.82); C498(0.93); C507(1.01); C237(1.04)  LDD0674  [3]
 LDCM0358  AC91 HCT 116 C202(0.75); C498(0.75); C507(0.78); C237(1.02)  LDD0675  [3]
 LDCM0359  AC92 HCT 116 C498(0.81); C507(0.84); C202(0.88); C237(1.00)  LDD0676  [3]
 LDCM0360  AC93 HCT 116 C202(0.81); C498(0.83); C507(0.99); C237(1.11)  LDD0677  [3]
 LDCM0361  AC94 HCT 116 C498(0.77); C507(0.81); C202(0.92); C307(1.04)  LDD0678  [3]
 LDCM0362  AC95 HCT 116 C202(0.77); C498(0.91); C507(1.06); C237(1.25)  LDD0679  [3]
 LDCM0363  AC96 HCT 116 C498(0.67); C507(0.73); C202(0.94); C237(1.14)  LDD0680  [3]
 LDCM0364  AC97 HCT 116 C202(1.01); C237(1.14); C507(1.44); C498(1.50)  LDD0681  [3]
 LDCM0365  AC98 HCT 116 C554(0.82); C237(0.90); C588(1.48); C507(1.71)  LDD0682  [3]
 LDCM0366  AC99 HCT 116 C237(0.62); C307(0.82); C313(0.90); C507(1.14)  LDD0683  [3]
 LDCM0248  AKOS034007472 HCT 116 C507(0.73); C498(0.73); C152(1.26); C307(1.34)  LDD0565  [3]
 LDCM0356  AKOS034007680 HCT 116 C507(0.75); C498(0.75); C554(0.84); C152(1.16)  LDD0673  [3]
 LDCM0275  AKOS034007705 HCT 116 C507(0.73); C498(0.73); C554(0.79); C307(0.90)  LDD0592  [3]
 LDCM0156  Aniline NCI-H1299 11.44  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C307(0.97); C313(0.97)  LDD0078  [3]
 LDCM0367  CL1 HCT 116 C307(0.86); C237(0.97)  LDD0684  [3]
 LDCM0368  CL10 HCT 116 C307(0.63); C237(0.82)  LDD0685  [3]
 LDCM0369  CL100 HCT 116 C507(0.81); C152(0.99); C588(1.08); C554(1.14)  LDD0686  [3]
 LDCM0370  CL101 HCT 116 C554(0.67); C307(0.97); C313(0.97); C507(1.07)  LDD0687  [3]
 LDCM0371  CL102 HCT 116 C307(0.88); C313(0.88); C554(0.94); C152(1.31)  LDD0688  [3]
 LDCM0372  CL103 HCT 116 C554(0.86); C507(0.93); C498(0.93); C307(1.02)  LDD0689  [3]
 LDCM0373  CL104 HCT 116 C507(0.84); C498(0.84); C554(0.89); C307(0.98)  LDD0690  [3]
 LDCM0374  CL105 HCT 116 C307(0.36); C391(0.44); C412(0.44); C498(0.79)  LDD0691  [3]
 LDCM0375  CL106 HCT 116 C307(0.36); C391(0.48); C412(0.48); C498(0.67)  LDD0692  [3]
 LDCM0376  CL107 HCT 116 C307(0.40); C391(0.46); C412(0.46); C498(0.67)  LDD0693  [3]
 LDCM0377  CL108 HCT 116 C307(0.27); C391(0.46); C412(0.46); C498(0.80)  LDD0694  [3]
 LDCM0378  CL109 HCT 116 C307(0.46); C391(0.50); C412(0.50); C507(0.92)  LDD0695  [3]
 LDCM0379  CL11 HCT 116 C307(0.65); C237(0.68)  LDD0696  [3]
 LDCM0380  CL110 HCT 116 C307(0.29); C391(0.46); C412(0.46); C498(0.95)  LDD0697  [3]
 LDCM0381  CL111 HCT 116 C307(0.33); C391(0.51); C412(0.51); C202(1.01)  LDD0698  [3]
 LDCM0382  CL112 HCT 116 C554(0.99); C588(1.17); C507(1.21); C152(1.56)  LDD0699  [3]
 LDCM0383  CL113 HCT 116 C588(0.97); C507(1.24); C152(1.38); C554(1.68)  LDD0700  [3]
 LDCM0384  CL114 HCT 116 C588(0.91); C152(1.38); C554(1.48); C507(1.63)  LDD0701  [3]
 LDCM0385  CL115 HCT 116 C588(1.18); C554(1.27); C152(1.65); C507(1.68)  LDD0702  [3]
 LDCM0386  CL116 HCT 116 C588(1.04); C507(1.05); C554(1.09); C152(1.52)  LDD0703  [3]
 LDCM0387  CL117 HCT 116 C554(1.24); C152(1.49); C237(1.52)  LDD0704  [3]
 LDCM0388  CL118 HCT 116 C554(1.02); C237(1.26); C152(1.36)  LDD0705  [3]
 LDCM0389  CL119 HCT 116 C152(1.09); C554(1.38); C237(1.58)  LDD0706  [3]
 LDCM0390  CL12 HCT 116 C307(0.76); C237(0.76)  LDD0707  [3]
 LDCM0391  CL120 HCT 116 C152(0.85); C554(1.20); C237(1.41)  LDD0708  [3]
 LDCM0392  CL121 HCT 116 C237(1.23)  LDD0709  [3]
 LDCM0393  CL122 HCT 116 C237(1.21)  LDD0710  [3]
 LDCM0394  CL123 HCT 116 C237(1.07)  LDD0711  [3]
 LDCM0395  CL124 HCT 116 C237(1.20)  LDD0712  [3]
 LDCM0396  CL125 HCT 116 C507(1.12); C152(1.33)  LDD0713  [3]
 LDCM0397  CL126 HCT 116 C152(1.00); C507(2.82)  LDD0714  [3]
 LDCM0398  CL127 HCT 116 C152(1.22); C507(1.73)  LDD0715  [3]
 LDCM0399  CL128 HCT 116 C507(0.92); C152(1.14)  LDD0716  [3]
 LDCM0400  CL13 HCT 116 C237(0.70); C307(0.82)  LDD0717  [3]
 LDCM0401  CL14 HCT 116 C307(0.86); C237(0.87)  LDD0718  [3]
 LDCM0402  CL15 HCT 116 C307(0.70); C237(0.78)  LDD0719  [3]
 LDCM0403  CL16 HCT 116 C391(1.00); C412(1.00); C507(1.21); C498(1.21)  LDD0720  [3]
 LDCM0404  CL17 HCT 116 C237(1.04); C507(1.09); C498(1.09); C554(1.16)  LDD0721  [3]
 LDCM0405  CL18 HCT 116 C507(0.90); C498(0.90); C554(1.11); C237(1.14)  LDD0722  [3]
 LDCM0406  CL19 HCT 116 C507(0.94); C498(0.94); C237(1.03); C554(1.06)  LDD0723  [3]
 LDCM0407  CL2 HCT 116 C307(1.05); C237(1.06)  LDD0724  [3]
 LDCM0408  CL20 HCT 116 C554(0.69); C507(1.04); C498(1.04); C237(1.29)  LDD0725  [3]
 LDCM0409  CL21 HCT 116 C554(0.97); C237(1.22); C507(3.19); C498(3.19)  LDD0726  [3]
 LDCM0410  CL22 HCT 116 C554(0.77); C237(1.07); C507(1.39); C498(1.39)  LDD0727  [3]
 LDCM0411  CL23 HCT 116 C554(0.77); C507(1.20); C498(1.20); C237(1.26)  LDD0728  [3]
 LDCM0412  CL24 HCT 116 C507(1.08); C498(1.08); C237(1.15); C554(0.89)  LDD0729  [3]
 LDCM0413  CL25 HCT 116 C507(1.16); C498(1.16); C237(1.32); C554(0.79)  LDD0730  [3]
 LDCM0414  CL26 HCT 116 C507(1.17); C498(1.17); C237(1.37); C554(0.87)  LDD0731  [3]
 LDCM0415  CL27 HCT 116 C507(1.07); C498(1.07); C237(1.43); C554(0.94)  LDD0732  [3]
 LDCM0416  CL28 HCT 116 C507(1.90); C498(1.90); C237(1.32); C554(0.63)  LDD0733  [3]
 LDCM0417  CL29 HCT 116 C507(1.09); C498(1.09); C237(1.38); C554(0.70)  LDD0734  [3]
 LDCM0418  CL3 HCT 116 C237(1.18); C307(0.90)  LDD0735  [3]
 LDCM0419  CL30 HCT 116 C507(1.05); C498(1.05); C237(1.46); C554(0.96)  LDD0736  [3]
 LDCM0420  CL31 HCT 116 C507(2.36); C202(0.84); C554(1.04)  LDD0737  [3]
 LDCM0421  CL32 HCT 116 C507(1.46); C498(1.35); C202(0.97); C391(1.28)  LDD0738  [3]
 LDCM0422  CL33 HCT 116 C507(2.55); C498(3.96); C202(1.27); C391(1.03)  LDD0739  [3]
 LDCM0423  CL34 HCT 116 C507(1.79); C498(1.66); C202(1.27); C391(1.15)  LDD0740  [3]
 LDCM0424  CL35 HCT 116 C507(1.43); C498(1.45); C202(1.04); C391(1.47)  LDD0741  [3]
 LDCM0425  CL36 HCT 116 C507(1.23); C498(1.07); C202(1.17); C391(1.32)  LDD0742  [3]
 LDCM0426  CL37 HCT 116 C507(1.47); C498(1.34); C202(0.99); C391(1.24)  LDD0743  [3]
 LDCM0428  CL39 HCT 116 C507(1.31); C498(1.17); C202(0.98); C391(1.14)  LDD0745  [3]
 LDCM0429  CL4 HCT 116 C237(0.76); C307(0.82)  LDD0746  [3]
 LDCM0430  CL40 HCT 116 C507(5.30); C498(1.48); C202(0.90); C391(1.03)  LDD0747  [3]
 LDCM0431  CL41 HCT 116 C507(1.46); C498(1.40); C202(0.93); C391(1.54)  LDD0748  [3]
 LDCM0432  CL42 HCT 116 C507(1.35); C498(0.95); C202(0.86); C391(1.19)  LDD0749  [3]
 LDCM0433  CL43 HCT 116 C507(1.59); C498(1.60); C202(1.12); C391(1.44)  LDD0750  [3]
 LDCM0434  CL44 HCT 116 C507(1.81); C498(1.44); C202(1.04); C391(1.36)  LDD0751  [3]
 LDCM0435  CL45 HCT 116 C507(1.32); C498(0.93); C202(0.99); C391(1.15)  LDD0752  [3]
 LDCM0436  CL46 HCT 116 C507(2.09); C498(1.88); C152(0.81); C237(1.19)  LDD0753  [3]
 LDCM0437  CL47 HCT 116 C507(1.15); C498(1.04); C152(0.66); C237(1.14)  LDD0754  [3]
 LDCM0438  CL48 HCT 116 C507(1.88); C498(1.72); C152(0.67); C237(1.21)  LDD0755  [3]
 LDCM0439  CL49 HCT 116 C507(1.17); C498(1.09); C152(1.06); C237(1.10)  LDD0756  [3]
 LDCM0440  CL5 HCT 116 C237(0.85); C307(0.86)  LDD0757  [3]
 LDCM0441  CL50 HCT 116 C507(1.31); C498(1.10); C152(0.74); C237(1.06)  LDD0758  [3]
 LDCM0442  CL51 HCT 116 C507(1.01); C498(1.18); C152(0.82); C237(1.15)  LDD0759  [3]
 LDCM0443  CL52 HCT 116 C507(1.55); C498(1.63); C152(0.78); C237(1.26)  LDD0760  [3]
 LDCM0444  CL53 HCT 116 C507(1.11); C498(1.02); C152(0.80); C237(1.00)  LDD0761  [3]
 LDCM0445  CL54 HCT 116 C507(1.25); C498(1.14); C152(0.70); C237(1.18)  LDD0762  [3]
 LDCM0446  CL55 HCT 116 C507(1.25); C498(1.16); C152(0.73); C237(0.96)  LDD0763  [3]
 LDCM0447  CL56 HCT 116 C507(1.20); C498(1.15); C152(0.97); C237(0.98)  LDD0764  [3]
 LDCM0448  CL57 HCT 116 C507(1.54); C498(1.44); C152(0.95); C237(1.11)  LDD0765  [3]
 LDCM0449  CL58 HCT 116 C507(1.84); C498(1.80); C152(0.77); C237(1.13)  LDD0766  [3]
 LDCM0450  CL59 HCT 116 C507(1.25); C498(1.39); C152(1.13); C237(1.05)  LDD0767  [3]
 LDCM0451  CL6 HCT 116 C237(1.03); C307(1.02)  LDD0768  [3]
 LDCM0452  CL60 HCT 116 C507(1.04); C498(1.12); C152(0.75); C237(1.10)  LDD0769  [3]
 LDCM0453  CL61 HCT 116 C152(0.98); C237(1.18); C554(1.06)  LDD0770  [3]
 LDCM0454  CL62 HCT 116 C152(0.85); C237(1.18); C554(0.99)  LDD0771  [3]
 LDCM0455  CL63 HCT 116 C152(0.96); C237(1.13); C554(0.90)  LDD0772  [3]
 LDCM0456  CL64 HCT 116 C152(1.20); C237(1.08); C554(1.07)  LDD0773  [3]
 LDCM0457  CL65 HCT 116 C152(0.94); C237(0.96); C554(0.90)  LDD0774  [3]
 LDCM0458  CL66 HCT 116 C152(1.56); C237(1.02); C554(1.07)  LDD0775  [3]
 LDCM0459  CL67 HCT 116 C152(1.30); C237(1.10); C554(0.98)  LDD0776  [3]
 LDCM0460  CL68 HCT 116 C152(1.09); C237(1.17); C554(0.75)  LDD0777  [3]
 LDCM0461  CL69 HCT 116 C152(1.07); C237(1.18); C554(1.06)  LDD0778  [3]
 LDCM0462  CL7 HCT 116 C237(0.70); C307(0.63)  LDD0779  [3]
 LDCM0463  CL70 HCT 116 C152(1.18); C237(0.99); C554(0.78)  LDD0780  [3]
 LDCM0464  CL71 HCT 116 C152(1.30); C237(0.99); C554(0.89)  LDD0781  [3]
 LDCM0465  CL72 HCT 116 C152(1.02); C237(1.65); C554(1.22)  LDD0782  [3]
 LDCM0466  CL73 HCT 116 C152(1.19); C237(1.05); C554(1.02)  LDD0783  [3]
 LDCM0467  CL74 HCT 116 C152(0.96); C237(1.49); C554(0.92)  LDD0784  [3]
 LDCM0469  CL76 HCT 116 C507(1.61); C498(1.91); C202(1.38); C237(1.18)  LDD0786  [3]
 LDCM0470  CL77 HCT 116 C507(1.40); C498(1.13); C202(0.86); C237(0.94)  LDD0787  [3]
 LDCM0471  CL78 HCT 116 C507(1.40); C498(1.67); C202(1.51); C237(0.92)  LDD0788  [3]
 LDCM0472  CL79 HCT 116 C507(1.29); C498(1.01); C202(1.09); C237(1.01)  LDD0789  [3]
 LDCM0473  CL8 HCT 116 C237(1.31); C307(0.96)  LDD0790  [3]
 LDCM0474  CL80 HCT 116 C507(1.17); C498(1.19); C202(1.02); C237(0.96)  LDD0791  [3]
 LDCM0475  CL81 HCT 116 C507(1.74); C498(2.22); C202(1.14); C237(0.99)  LDD0792  [3]
 LDCM0476  CL82 HCT 116 C507(0.90); C498(0.88); C202(1.32); C237(0.98)  LDD0793  [3]
 LDCM0477  CL83 HCT 116 C507(1.10); C498(0.83); C202(1.12); C237(1.14)  LDD0794  [3]
 LDCM0478  CL84 HCT 116 C507(1.31); C498(1.30); C202(1.70); C237(1.30)  LDD0795  [3]
 LDCM0479  CL85 HCT 116 C507(1.13); C498(1.15); C202(1.23); C237(1.08)  LDD0796  [3]
 LDCM0480  CL86 HCT 116 C507(1.17); C498(1.36); C202(1.04); C237(0.87)  LDD0797  [3]
 LDCM0481  CL87 HCT 116 C507(1.28); C498(1.30); C202(1.32); C237(1.05)  LDD0798  [3]
 LDCM0482  CL88 HCT 116 C507(1.10); C498(1.14); C202(1.78); C237(1.00)  LDD0799  [3]
 LDCM0483  CL89 HCT 116 C507(1.01); C498(1.09); C202(1.64); C237(0.92)  LDD0800  [3]
 LDCM0484  CL9 HCT 116 C237(0.81); C307(0.82)  LDD0801  [3]
 LDCM0485  CL90 HCT 116 C507(5.08); C498(5.42); C202(0.98); C237(0.88)  LDD0802  [3]
 LDCM0486  CL91 HCT 116 C507(1.20); C152(1.35); C391(0.94); C412(0.94)  LDD0803  [3]
 LDCM0487  CL92 HCT 116 C507(1.73); C152(0.88); C391(1.02); C412(1.02)  LDD0804  [3]
 LDCM0488  CL93 HCT 116 C507(0.83); C152(0.73); C391(0.99); C412(0.99)  LDD0805  [3]
 LDCM0489  CL94 HCT 116 C507(1.22); C152(1.41); C391(1.29); C412(1.29)  LDD0806  [3]
 LDCM0490  CL95 HCT 116 C507(1.67); C152(1.03); C391(0.92); C412(0.92)  LDD0807  [3]
 LDCM0491  CL96 HCT 116 C507(1.15); C152(1.08); C391(1.03); C412(1.03)  LDD0808  [3]
 LDCM0492  CL97 HCT 116 C507(1.10); C152(1.03); C391(1.20); C412(1.20)  LDD0809  [3]
 LDCM0493  CL98 HCT 116 C507(1.01); C152(1.13); C391(1.21); C412(1.21)  LDD0810  [3]
 LDCM0494  CL99 HCT 116 C507(0.91); C152(0.91); C391(1.09); C412(1.09)  LDD0811  [3]
 LDCM0495  E2913 HEK-293T C1206(1.21); C202(1.08); C507(2.18)  LDD1698  [10]
 LDCM0468  Fragment33 HCT 116 C152(1.26); C237(1.26); C554(0.97)  LDD0785  [3]
 LDCM0427  Fragment51 HCT 116 C507(4.97); C498(1.09); C202(0.71); C391(1.05)  LDD0744  [3]
 LDCM0022  KB02 HCT 116 C307(2.48); C313(2.48); C62(1.68)  LDD0080  [3]
 LDCM0023  KB03 HCT 116 C307(1.61); C313(1.61); C62(1.37)  LDD0081  [3]
 LDCM0024  KB05 HCT 116 C307(2.07); C313(2.07); C62(1.67)  LDD0082  [3]
 LDCM0021  THZ1 HCT 116 C307(1.10); C313(1.10)  LDD2173  [3]

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
3 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
4 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
5 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
6 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
7 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
8 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
9 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
10 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402