Details of the Target

General Information of Target

Target ID LDTP08036
Target Name Pogo transposable element with ZNF domain (POGZ)
Gene Name POGZ
Gene ID 23126
Synonyms
KIAA0461; SUHW5; ZNF280E; ZNF635; Pogo transposable element with ZNF domain; Suppressor of hairy wing homolog 5; Zinc finger protein 280E; Zinc finger protein 635
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MADTDLFMECEEEELEPWQKISDVIEDSVVEDYNSVDKTTTVSVSQQPVSAPVPIAAHAS
VAGHLSTSTTVSSSGAQNSDSTKKTLVTLIANNNAGNPLVQQGGQPLILTQNPAPGLGTM
VTQPVLRPVQVMQNANHVTSSPVASQPIFITTQGFPVRNVRPVQNAMNQVGIVLNVQQGQ
TVRPITLVPAPGTQFVKPTVGVPQVFSQMTPVRPGSTMPVRPTTNTFTTVIPATLTIRST
VPQSQSQQTKSTPSTSTTPTATQPTSLGQLAVQSPGQSNQTTNPKLAPSFPSPPAVSIAS
FVTVKRPGVTGENSNEVAKLVNTLNTIPSLGQSPGPVVVSNNSSAHGSQRTSGPESSMKV
TSSIPVFDLQDGGRKICPRCNAQFRVTEALRGHMCYCCPEMVEYQKKGKSLDSEPSVPSA
AKPPSPEKTAPVASTPSSTPIPALSPPTKVPEPNENVGDAVQTKLIMLVDDFYYGRDGGK
VAQLTNFPKVATSFRCPHCTKRLKNNIRFMNHMKHHVELDQQNGEVDGHTICQHCYRQFS
TPFQLQCHLENVHSPYESTTKCKICEWAFESEPLFLQHMKDTHKPGEMPYVCQVCQYRSS
LYSEVDVHFRMIHEDTRHLLCPYCLKVFKNGNAFQQHYMRHQKRNVYHCNKCRLQFLFAK
DKIEHKLQHHKTFRKPKQLEGLKPGTKVTIRASRGQPRTVPVSSNDTPPSALQEAAPLTS
SMDPLPVFLYPPVQRSIQKRAVRKMSVMGRQTCLECSFEIPDFPNHFPTYVHCSLCRYST
CCSRAYANHMINNHVPRKSPKYLALFKNSVSGIKLACTSCTFVTSVGDAMAKHLVFNPSH
RSSSILPRGLTWIAHSRHGQTRDRVHDRNVKNMYPPPSFPTNKAATVKSAGATPAEPEEL
LTPLAPALPSPASTATPPPTPTHPQALALPPLATEGAECLNVDDQDEGSPVTQEPELASG
GGGSGGVGKKEQLSVKKLRVVLFALCCNTEQAAEHFRNPQRRIRRWLRRFQASQGENLEG
KYLSFEAEEKLAEWVLTQREQQLPVNEETLFQKATKIGRSLEGGFKISYEWAVRFMLRHH
LTPHARRAVAHTLPKDVAENAGLFIDFVQRQIHNQDLPLSMIVAIDEISLFLDTEVLSSD
DRKENALQTVGTGEPWCDVVLAILADGTVLPTLVFYRGQMDQPANMPDSILLEAKESGYS
DDEIMELWSTRVWQKHTACQRSKGMLVMDCHRTHLSEEVLAMLSASSTLPAVVPAGCSSK
IQPLDVCIKRTVKNFLHKKWKEQAREMADTACDSDVLLQLVLVWLGEVLGVIGDCPELVQ
RSFLVASVLPGPDGNINSPTRNADMQEELIASLEEQLKLSGEHSESSTPRPRSSPEETIE
PESLHQLFEGESETESFYGFEEADLDLMEI
Target Bioclass
Transcription factor
Subcellular location
Nucleus
Function
Plays a role in mitotic cell cycle progression and is involved in kinetochore assembly and mitotic sister chromatid cohesion. Probably through its association with CBX5 plays a role in mitotic chromosome segregation by regulating aurora kinase B/AURKB activation and AURKB and CBX5 dissociation from chromosome arms. Promotes the repair of DNA double-strand breaks through the homologous recombination pathway.
Uniprot ID
Q7Z3K3
Ensemble ID
ENST00000271715.7
HGNC ID
HGNC:18801

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
HCT15 SNV: p.V143M DBIA    Probe Info 
HT115 SNV: p.R653W DBIA    Probe Info 
HUCCT1 Substitution: p.P838F DBIA    Probe Info 
HUH28 SNV: p.T217I DBIA    Probe Info 
ICC10 SNV: p.G75E DBIA    Probe Info 
JHH4 SNV: p.A51T DBIA    Probe Info 
MCC13 SNV: p.S410F DBIA    Probe Info 
MEWO SNV: p.P431S DBIA    Probe Info 
NCIH196 SNV: p.Q544H DBIA    Probe Info 
PANC1 SNV: p.L657F DBIA    Probe Info 
U118MG SNV: p.S329F DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 21 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
BTD
 Probe Info  		C782(0.81)  LDD2090  [2]
AHL-Pu-1
 Probe Info  		C1219(8.60)  LDD0168  [3]
Acrolein
 Probe Info  		N.A.  LDD0222  [4]
DBIA
 Probe Info  		C987(1.15); C395(0.95); C397(0.95); C398(0.95)  LDD0078  [5]
4-Iodoacetamidophenylacetylene
 Probe Info  		C1230(0.00); C565(0.00); C1267(0.00); C1257(0.00)  LDD0038  [6]
IA-alkyne
 Probe Info  		N.A.  LDD0032  [7]
IPIAA_L
 Probe Info  		N.A.  LDD0031  [8]
Lodoacetamide azide
 Probe Info  		C1230(0.00); C565(0.00); C1267(0.00); C547(0.00)  LDD0037  [6]
TFBX
 Probe Info  		N.A.  LDD0027  [9]
WYneN
 Probe Info  		N.A.  LDD0021  [10]
ENE
 Probe Info  		N.A.  LDD0006  [10]
IPM
 Probe Info  		N.A.  LDD0005  [10]
NHS
 Probe Info  		N.A.  LDD0010  [10]
STPyne
 Probe Info  		N.A.  LDD0009  [10]
VSF
 Probe Info  		N.A.  LDD0007  [10]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [11]
Crotonaldehyde
 Probe Info  		N.A.  LDD0219  [4]
Methacrolein
 Probe Info  		C1267(0.00); C1219(0.00); C781(0.00)  LDD0218  [4]
AOyne
 Probe Info  		8.10  LDD0443  [12]
NAIA_5
 Probe Info  		N.A.  LDD2223  [13]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA HEK-293T C1219(8.60)  LDD0168  [3]
 LDCM0026  4SU-RNA+native RNA HEK-293T C1219(2.45)  LDD0169  [3]
 LDCM0214  AC1 HCT 116 C1230(1.20); C1267(0.87); C592(1.38); C595(1.38)  LDD0531  [5]
 LDCM0215  AC10 HCT 116 C1230(1.09); C592(0.77); C595(0.77); C781(0.86)  LDD0532  [5]
 LDCM0216  AC100 HCT 116 C1230(0.77); C1267(0.63); C397(0.84); C398(0.94)  LDD0533  [5]
 LDCM0217  AC101 HCT 116 C1230(0.78); C1267(0.68); C397(0.75); C398(0.67)  LDD0534  [5]
 LDCM0218  AC102 HCT 116 C1230(0.76); C1267(0.63); C397(0.98); C398(1.24)  LDD0535  [5]
 LDCM0219  AC103 HCT 116 C1230(0.94); C1267(0.74); C397(0.81); C398(0.85)  LDD0536  [5]
 LDCM0220  AC104 HCT 116 C1230(0.86); C1267(0.74); C397(1.19); C398(1.09)  LDD0537  [5]
 LDCM0221  AC105 HCT 116 C1230(0.90); C1267(0.65); C397(0.93); C398(1.10)  LDD0538  [5]
 LDCM0222  AC106 HCT 116 C1230(0.90); C1267(0.77); C397(0.94); C398(1.05)  LDD0539  [5]
 LDCM0223  AC107 HCT 116 C1230(1.02); C1267(1.50); C397(0.96); C398(1.33)  LDD0540  [5]
 LDCM0224  AC108 HCT 116 C1230(0.84); C1267(0.79); C397(1.05); C398(0.97)  LDD0541  [5]
 LDCM0225  AC109 HCT 116 C1230(0.79); C1267(0.73); C397(0.77); C398(1.12)  LDD0542  [5]
 LDCM0226  AC11 HCT 116 C1230(1.13); C592(0.87); C595(0.87); C781(0.83)  LDD0543  [5]
 LDCM0227  AC110 HCT 116 C1230(0.81); C1267(0.71); C397(0.87); C398(0.87)  LDD0544  [5]
 LDCM0228  AC111 HCT 116 C1230(0.86); C1267(0.86); C397(0.93); C398(0.97)  LDD0545  [5]
 LDCM0229  AC112 HCT 116 C1230(0.99); C1267(1.04); C397(1.10); C398(1.03)  LDD0546  [5]
 LDCM0230  AC113 HCT 116 C1230(0.96); C1267(0.99); C397(0.95); C398(0.95)  LDD0547  [5]
 LDCM0231  AC114 HCT 116 C1230(0.97); C1267(1.00); C397(1.03); C398(1.00)  LDD0548  [5]
 LDCM0232  AC115 HCT 116 C1230(1.16); C1267(1.08); C397(1.26); C398(1.21)  LDD0549  [5]
 LDCM0233  AC116 HCT 116 C1230(1.07); C1267(1.12); C397(1.11); C398(1.09)  LDD0550  [5]
 LDCM0234  AC117 HCT 116 C1230(1.29); C1267(0.93); C397(0.77); C398(0.77)  LDD0551  [5]
 LDCM0235  AC118 HCT 116 C1230(1.02); C1267(0.87); C397(0.93); C398(0.93)  LDD0552  [5]
 LDCM0236  AC119 HCT 116 C1230(1.15); C1267(0.94); C397(1.49); C398(1.45)  LDD0553  [5]
 LDCM0237  AC12 HCT 116 C1230(1.10); C592(0.81); C595(0.81); C781(0.80)  LDD0554  [5]
 LDCM0238  AC120 HCT 116 C1230(1.02); C1267(1.04); C397(1.20); C398(1.17)  LDD0555  [5]
 LDCM0239  AC121 HCT 116 C1230(1.54); C1267(0.95); C397(0.89); C398(0.93)  LDD0556  [5]
 LDCM0240  AC122 HCT 116 C1230(1.08); C1267(1.09); C397(0.80); C398(0.75)  LDD0557  [5]
 LDCM0241  AC123 HCT 116 C1230(1.23); C1267(0.88); C397(0.83); C398(0.85)  LDD0558  [5]
 LDCM0242  AC124 HCT 116 C1230(1.15); C1267(1.04); C397(0.98); C398(0.98)  LDD0559  [5]
 LDCM0243  AC125 HCT 116 C1230(0.90); C1267(0.97); C397(1.01); C398(1.00)  LDD0560  [5]
 LDCM0244  AC126 HCT 116 C1230(1.07); C1267(1.23); C397(1.05); C398(1.05)  LDD0561  [5]
 LDCM0245  AC127 HCT 116 C1230(1.16); C1267(1.15); C397(0.97); C398(0.97)  LDD0562  [5]
 LDCM0246  AC128 HCT 116 C1230(1.35); C1267(1.61); C397(0.31); C398(0.31)  LDD0563  [5]
 LDCM0247  AC129 HCT 116 C1230(0.95); C1267(1.29); C397(0.26); C398(0.26)  LDD0564  [5]
 LDCM0249  AC130 HCT 116 C1230(1.10); C1267(1.11); C397(0.28); C398(0.28)  LDD0566  [5]
 LDCM0250  AC131 HCT 116 C1230(0.99); C1267(1.27); C397(0.35); C398(0.35)  LDD0567  [5]
 LDCM0251  AC132 HCT 116 C1230(1.01); C1267(1.09); C397(0.29); C398(0.29)  LDD0568  [5]
 LDCM0252  AC133 HCT 116 C1230(1.11); C1267(1.05); C397(0.34); C398(0.34)  LDD0569  [5]
 LDCM0253  AC134 HCT 116 C1230(1.15); C1267(1.13); C397(0.45); C398(0.45)  LDD0570  [5]
 LDCM0254  AC135 HCT 116 C1230(1.11); C1267(1.17); C397(0.35); C398(0.35)  LDD0571  [5]
 LDCM0255  AC136 HCT 116 C1230(1.08); C1267(1.06); C397(0.39); C398(0.39)  LDD0572  [5]
 LDCM0256  AC137 HCT 116 C1230(1.04); C1267(1.10); C397(0.37); C398(0.37)  LDD0573  [5]
 LDCM0257  AC138 HCT 116 C1230(1.09); C1267(1.01); C397(0.63); C398(0.63)  LDD0574  [5]
 LDCM0258  AC139 HCT 116 C1230(1.12); C1267(1.09); C397(0.37); C398(0.37)  LDD0575  [5]
 LDCM0259  AC14 HCT 116 C1230(1.04); C592(1.10); C595(1.10); C781(0.96)  LDD0576  [5]
 LDCM0260  AC140 HCT 116 C1230(1.16); C1267(1.25); C397(0.42); C398(0.42)  LDD0577  [5]
 LDCM0261  AC141 HCT 116 C1230(1.02); C1267(1.18); C397(0.40); C398(0.40)  LDD0578  [5]
 LDCM0262  AC142 HCT 116 C1230(1.00); C1267(1.11); C397(0.38); C398(0.38)  LDD0579  [5]
 LDCM0263  AC143 HCT 116 C592(0.83); C595(0.83); C986(0.84); C987(0.84)  LDD0580  [5]
 LDCM0264  AC144 HCT 116 C592(0.46); C595(0.46); C781(0.97); C1230(1.08)  LDD0581  [5]
 LDCM0265  AC145 HCT 116 C592(0.64); C595(0.64); C781(0.78); C987(0.97)  LDD0582  [5]
 LDCM0266  AC146 HCT 116 C592(0.68); C595(0.68); C986(1.06); C1230(1.07)  LDD0583  [5]
 LDCM0267  AC147 HCT 116 C592(0.48); C595(0.48); C781(0.95); C987(1.10)  LDD0584  [5]
 LDCM0268  AC148 HCT 116 C592(0.60); C595(0.60); C781(1.18); C397(1.33)  LDD0585  [5]
 LDCM0269  AC149 HCT 116 C592(0.53); C595(0.53); C781(1.01); C986(1.05)  LDD0586  [5]
 LDCM0270  AC15 HCT 116 C592(0.72); C595(0.72); C781(0.91); C986(0.95)  LDD0587  [5]
 LDCM0271  AC150 HCT 116 C592(0.75); C595(0.75); C986(0.88); C987(1.02)  LDD0588  [5]
 LDCM0272  AC151 HCT 116 C592(0.66); C595(0.66); C1230(0.89); C781(1.07)  LDD0589  [5]
 LDCM0273  AC152 HCT 116 C592(0.62); C595(0.62); C781(0.75); C397(1.07)  LDD0590  [5]
 LDCM0274  AC153 HCT 116 C592(0.58); C595(0.58); C781(1.17); C397(1.44)  LDD0591  [5]
 LDCM0621  AC154 HCT 116 C1230(1.04); C397(1.81); C398(1.81); C592(0.55)  LDD2158  [5]
 LDCM0622  AC155 HCT 116 C1230(1.01); C397(1.18); C398(1.18); C592(0.60)  LDD2159  [5]
 LDCM0623  AC156 HCT 116 C1230(0.99); C397(1.26); C398(1.26); C592(0.73)  LDD2160  [5]
 LDCM0624  AC157 HCT 116 C1230(0.88); C397(1.09); C398(1.09); C592(0.57)  LDD2161  [5]
 LDCM0276  AC17 HCT 116 C986(0.92); C987(0.92); C782(0.95); C781(1.01)  LDD0593  [5]
 LDCM0277  AC18 HCT 116 C782(0.82); C781(0.90); C986(0.91); C987(0.91)  LDD0594  [5]
 LDCM0278  AC19 HCT 116 C782(0.73); C781(0.75); C986(0.98); C987(0.98)  LDD0595  [5]
 LDCM0279  AC2 HCT 116 C986(0.87); C987(0.87); C1267(0.96); C592(0.99)  LDD0596  [5]
 LDCM0280  AC20 HCT 116 C782(0.77); C781(0.78); C1230(0.98); C986(0.99)  LDD0597  [5]
 LDCM0281  AC21 HCT 116 C781(0.79); C782(0.81); C986(1.09); C987(1.09)  LDD0598  [5]
 LDCM0282  AC22 HCT 116 C782(0.82); C781(0.89); C986(0.92); C987(0.92)  LDD0599  [5]
 LDCM0283  AC23 HCT 116 C986(0.93); C987(0.93); C782(1.04); C781(1.15)  LDD0600  [5]
 LDCM0284  AC24 HCT 116 C781(0.84); C782(0.91); C986(1.03); C987(1.03)  LDD0601  [5]
 LDCM0285  AC25 HCT 116 C782(0.63); C547(0.73); C781(0.77); C592(0.81)  LDD0602  [5]
 LDCM0286  AC26 HCT 116 C782(0.56); C781(0.63); C817(0.81); C820(0.81)  LDD0603  [5]
 LDCM0287  AC27 HCT 116 C782(0.51); C781(0.64); C592(0.76); C595(0.76)  LDD0604  [5]
 LDCM0288  AC28 HCT 116 C782(0.57); C817(0.73); C820(0.73); C781(0.74)  LDD0605  [5]
 LDCM0289  AC29 HCT 116 C817(0.43); C820(0.43); C781(0.62); C782(0.63)  LDD0606  [5]
 LDCM0290  AC3 HCT 116 C986(0.86); C987(0.86); C1267(0.87); C592(0.97)  LDD0607  [5]
 LDCM0291  AC30 HCT 116 C817(0.50); C820(0.50); C782(0.59); C781(0.63)  LDD0608  [5]
 LDCM0292  AC31 HCT 116 C782(0.59); C781(0.71); C817(0.76); C820(0.76)  LDD0609  [5]
 LDCM0293  AC32 HCT 116 C817(0.47); C820(0.47); C782(0.67); C781(0.76)  LDD0610  [5]
 LDCM0294  AC33 HCT 116 C782(0.52); C781(0.56); C592(0.72); C595(0.72)  LDD0611  [5]
 LDCM0295  AC34 HCT 116 C782(0.61); C592(0.63); C595(0.63); C817(0.68)  LDD0612  [5]
 LDCM0296  AC35 HCT 116 C1230(1.04); C781(1.18); C782(1.18); C592(1.33)  LDD0613  [5]
 LDCM0297  AC36 HCT 116 C1230(0.93); C592(0.93); C595(0.93); C781(1.13)  LDD0614  [5]
 LDCM0298  AC37 HCT 116 C592(0.94); C595(0.94); C1230(1.02); C781(1.10)  LDD0615  [5]
 LDCM0299  AC38 HCT 116 C1230(1.01); C781(1.06); C782(1.06); C592(1.08)  LDD0616  [5]
 LDCM0300  AC39 HCT 116 C592(1.01); C595(1.01); C1230(1.05); C781(1.38)  LDD0617  [5]
 LDCM0301  AC4 HCT 116 C986(0.95); C987(0.95); C1267(0.98); C592(1.02)  LDD0618  [5]
 LDCM0302  AC40 HCT 116 C592(0.84); C595(0.84); C1230(1.05); C781(1.32)  LDD0619  [5]
 LDCM0303  AC41 HCT 116 C592(0.94); C595(0.94); C1230(1.06); C781(1.20)  LDD0620  [5]
 LDCM0304  AC42 HCT 116 C1230(1.10); C592(1.12); C595(1.12); C781(1.20)  LDD0621  [5]
 LDCM0305  AC43 HCT 116 C781(0.90); C782(0.90); C592(1.02); C595(1.02)  LDD0622  [5]
 LDCM0306  AC44 HCT 116 C592(0.87); C595(0.87); C1230(1.08); C781(1.23)  LDD0623  [5]
 LDCM0307  AC45 HCT 116 C592(0.79); C595(0.79); C781(1.15); C782(1.15)  LDD0624  [5]
 LDCM0308  AC46 HCT 116 C781(0.88); C986(0.94); C987(0.94); C1230(1.01)  LDD0625  [5]
 LDCM0309  AC47 HCT 116 C592(0.81); C595(0.81); C781(0.86); C986(0.91)  LDD0626  [5]
 LDCM0310  AC48 HCT 116 C986(0.81); C987(0.81); C592(1.02); C595(1.02)  LDD0627  [5]
 LDCM0311  AC49 HCT 116 C781(0.99); C986(1.15); C987(1.15); C1230(1.27)  LDD0628  [5]
 LDCM0312  AC5 HCT 116 C986(0.85); C987(0.85); C592(0.95); C595(0.95)  LDD0629  [5]
 LDCM0313  AC50 HCT 116 C592(0.87); C595(0.87); C781(0.92); C782(1.08)  LDD0630  [5]
 LDCM0314  AC51 HCT 116 C1230(1.00); C592(1.02); C595(1.02); C986(1.09)  LDD0631  [5]
 LDCM0315  AC52 HCT 116 C592(0.98); C595(0.98); C986(1.03); C987(1.03)  LDD0632  [5]
 LDCM0316  AC53 HCT 116 C592(0.82); C595(0.82); C781(1.00); C1230(1.08)  LDD0633  [5]
 LDCM0317  AC54 HCT 116 C592(0.84); C595(0.84); C986(1.07); C987(1.07)  LDD0634  [5]
 LDCM0318  AC55 HCT 116 C592(0.82); C595(0.82); C781(0.99); C986(1.08)  LDD0635  [5]
 LDCM0319  AC56 HCT 116 C592(0.90); C595(0.90); C781(1.02); C1230(1.46)  LDD0636  [5]
 LDCM0320  AC57 HCT 116 C817(0.55); C820(0.55); C398(0.88); C986(1.01)  LDD0637  [5]
 LDCM0321  AC58 HCT 116 C817(0.66); C820(0.66); C398(1.25); C1230(1.25)  LDD0638  [5]
 LDCM0322  AC59 HCT 116 C817(0.57); C820(0.57); C986(1.04); C987(1.04)  LDD0639  [5]
 LDCM0323  AC6 HCT 116 C592(0.76); C595(0.76); C781(0.92); C1230(0.95)  LDD0640  [5]
 LDCM0324  AC60 HCT 116 C817(0.65); C820(0.65); C398(0.97); C986(1.06)  LDD0641  [5]
 LDCM0325  AC61 HCT 116 C817(0.77); C820(0.77); C986(0.92); C987(0.92)  LDD0642  [5]
 LDCM0326  AC62 HCT 116 C817(0.63); C820(0.63); C398(0.99); C986(1.23)  LDD0643  [5]
 LDCM0327  AC63 HCT 116 C817(0.67); C820(0.67); C398(1.03); C986(1.17)  LDD0644  [5]
 LDCM0328  AC64 HCT 116 C817(0.64); C820(0.64); C398(0.96); C986(1.32)  LDD0645  [5]
 LDCM0329  AC65 HCT 116 C817(0.69); C820(0.69); C986(0.95); C987(0.95)  LDD0646  [5]
 LDCM0330  AC66 HCT 116 C817(0.67); C820(0.67); C986(0.99); C987(0.99)  LDD0647  [5]
 LDCM0331  AC67 HCT 116 C817(0.64); C820(0.64); C986(1.07); C987(1.07)  LDD0648  [5]
 LDCM0332  AC68 HCT 116 C782(0.82); C817(0.96); C820(0.96); C592(1.00)  LDD0649  [5]
 LDCM0333  AC69 HCT 116 C398(0.77); C782(0.89); C397(0.92); C592(0.97)  LDD0650  [5]
 LDCM0334  AC7 HCT 116 C781(0.86); C592(0.87); C595(0.87); C782(0.90)  LDD0651  [5]
 LDCM0335  AC70 HCT 116 C398(0.68); C397(0.75); C817(0.76); C820(0.76)  LDD0652  [5]
 LDCM0336  AC71 HCT 116 C398(0.73); C782(0.86); C986(0.93); C987(0.93)  LDD0653  [5]
 LDCM0337  AC72 HCT 116 C592(0.76); C595(0.76); C398(0.77); C782(0.91)  LDD0654  [5]
 LDCM0338  AC73 HCT 116 C592(0.87); C595(0.87); C398(0.96); C397(1.10)  LDD0655  [5]
 LDCM0339  AC74 HCT 116 C398(0.75); C397(0.78); C592(0.95); C595(0.95)  LDD0656  [5]
 LDCM0340  AC75 HCT 116 C397(0.78); C398(0.84); C782(1.02); C592(1.02)  LDD0657  [5]
 LDCM0341  AC76 HCT 116 C398(0.66); C592(0.79); C595(0.79); C397(0.80)  LDD0658  [5]
 LDCM0342  AC77 HCT 116 C592(0.88); C595(0.88); C986(1.03); C987(1.03)  LDD0659  [5]
 LDCM0343  AC78 HCT 116 C782(0.89); C398(0.90); C986(1.00); C987(1.00)  LDD0660  [5]
 LDCM0344  AC79 HCT 116 C398(0.81); C782(0.82); C397(0.83); C592(0.88)  LDD0661  [5]
 LDCM0345  AC8 HCT 116 C986(0.89); C987(0.89); C592(0.92); C595(0.92)  LDD0662  [5]
 LDCM0346  AC80 HCT 116 C398(0.75); C592(0.78); C595(0.78); C817(0.90)  LDD0663  [5]
 LDCM0347  AC81 HCT 116 C398(0.69); C986(0.88); C987(0.88); C782(0.93)  LDD0664  [5]
 LDCM0348  AC82 HCT 116 C398(0.76); C397(0.76); C592(1.11); C595(1.11)  LDD0665  [5]
 LDCM0349  AC83 HCT 116 C592(0.43); C595(0.43); C986(0.88); C987(1.08)  LDD0666  [5]
 LDCM0350  AC84 HCT 116 C592(0.55); C595(0.55); C986(0.77); C782(0.97)  LDD0667  [5]
 LDCM0351  AC85 HCT 116 C592(0.57); C595(0.57); C782(0.84); C781(0.90)  LDD0668  [5]
 LDCM0352  AC86 HCT 116 C592(0.45); C595(0.45); C986(0.61); C782(0.67)  LDD0669  [5]
 LDCM0353  AC87 HCT 116 C986(0.46); C592(0.66); C595(0.66); C782(0.79)  LDD0670  [5]
 LDCM0354  AC88 HCT 116 C592(0.59); C595(0.59); C782(0.68); C986(0.77)  LDD0671  [5]
 LDCM0355  AC89 HCT 116 C592(0.43); C595(0.43); C782(0.76); C986(0.81)  LDD0672  [5]
 LDCM0357  AC90 HCT 116 C986(0.63); C592(0.66); C595(0.66); C782(0.77)  LDD0674  [5]
 LDCM0358  AC91 HCT 116 C592(0.44); C595(0.44); C782(1.00); C781(1.19)  LDD0675  [5]
 LDCM0359  AC92 HCT 116 C592(0.39); C595(0.39); C986(0.87); C782(0.92)  LDD0676  [5]
 LDCM0360  AC93 HCT 116 C592(0.42); C595(0.42); C986(0.45); C987(0.76)  LDD0677  [5]
 LDCM0361  AC94 HCT 116 C592(0.64); C595(0.64); C986(0.65); C987(0.91)  LDD0678  [5]
 LDCM0362  AC95 HCT 116 C592(0.70); C595(0.70); C986(0.91); C782(0.91)  LDD0679  [5]
 LDCM0363  AC96 HCT 116 C592(0.45); C595(0.45); C986(0.82); C987(0.97)  LDD0680  [5]
 LDCM0364  AC97 HCT 116 C592(0.45); C595(0.45); C782(0.77); C986(0.81)  LDD0681  [5]
 LDCM0365  AC98 HCT 116 C592(0.42); C595(0.42); C782(0.55); C817(0.67)  LDD0682  [5]
 LDCM0366  AC99 HCT 116 C592(0.61); C595(0.61); C782(0.61); C1267(0.63)  LDD0683  [5]
 LDCM0248  AKOS034007472 HCT 116 C1230(0.98); C592(0.82); C595(0.82); C781(0.90)  LDD0565  [5]
 LDCM0356  AKOS034007680 HCT 116 C781(0.76); C782(0.87); C592(0.92); C595(0.92)  LDD0673  [5]
 LDCM0275  AKOS034007705 HCT 116 C592(0.64); C595(0.64); C782(0.91); C781(0.92)  LDD0592  [5]
 LDCM0156  Aniline NCI-H1299 11.41  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C987(1.15); C395(0.95); C397(0.95); C398(0.95)  LDD0078  [5]
 LDCM0108  Chloroacetamide HeLa N.A.  LDD0222  [4]
 LDCM0367  CL1 HCT 116 C1230(0.83); C592(0.97); C595(0.97); C817(1.03)  LDD0684  [5]
 LDCM0368  CL10 HCT 116 C592(0.71); C595(0.71); C817(0.76); C820(0.76)  LDD0685  [5]
 LDCM0369  CL100 HCT 116 C986(0.85); C987(0.85); C592(0.89); C595(0.89)  LDD0686  [5]
 LDCM0370  CL101 HCT 116 C592(0.79); C595(0.79); C781(0.82); C782(0.86)  LDD0687  [5]
 LDCM0371  CL102 HCT 116 C781(0.73); C592(0.74); C595(0.74); C782(0.80)  LDD0688  [5]
 LDCM0372  CL103 HCT 116 C782(0.87); C781(0.91); C1230(0.93); C592(1.02)  LDD0689  [5]
 LDCM0373  CL104 HCT 116 C781(0.80); C592(0.84); C595(0.84); C782(0.88)  LDD0690  [5]
 LDCM0374  CL105 HCT 116 C782(0.88); C781(0.93); C986(1.03); C987(1.03)  LDD0691  [5]
 LDCM0375  CL106 HCT 116 C782(0.78); C781(0.82); C986(1.18); C987(1.18)  LDD0692  [5]
 LDCM0376  CL107 HCT 116 C782(0.75); C781(0.93); C986(1.04); C987(1.04)  LDD0693  [5]
 LDCM0377  CL108 HCT 116 C782(0.84); C781(0.87); C986(1.15); C987(1.15)  LDD0694  [5]
 LDCM0378  CL109 HCT 116 C782(0.72); C781(0.75); C986(1.02); C987(1.02)  LDD0695  [5]
 LDCM0379  CL11 HCT 116 C592(0.69); C595(0.69); C817(0.84); C820(0.84)  LDD0696  [5]
 LDCM0380  CL110 HCT 116 C781(0.70); C782(0.80); C986(1.07); C987(1.07)  LDD0697  [5]
 LDCM0381  CL111 HCT 116 C781(0.76); C782(0.83); C986(1.04); C987(1.04)  LDD0698  [5]
 LDCM0382  CL112 HCT 116 C782(0.67); C817(0.75); C820(0.75); C986(0.87)  LDD0699  [5]
 LDCM0383  CL113 HCT 116 C817(0.50); C820(0.50); C782(0.70); C592(0.75)  LDD0700  [5]
 LDCM0384  CL114 HCT 116 C817(0.41); C820(0.41); C782(0.66); C781(0.79)  LDD0701  [5]
 LDCM0385  CL115 HCT 116 C817(0.45); C820(0.45); C782(0.61); C781(0.73)  LDD0702  [5]
 LDCM0386  CL116 HCT 116 C782(0.56); C817(0.70); C820(0.70); C592(0.79)  LDD0703  [5]
 LDCM0387  CL117 HCT 116 C592(1.04); C595(1.04); C1230(1.16); C781(1.29)  LDD0704  [5]
 LDCM0388  CL118 HCT 116 C592(0.88); C595(0.88); C1230(1.06); C781(1.07)  LDD0705  [5]
 LDCM0389  CL119 HCT 116 C592(0.97); C595(0.97); C1230(1.08); C781(1.12)  LDD0706  [5]
 LDCM0390  CL12 HCT 116 C592(0.64); C595(0.64); C817(0.78); C820(0.78)  LDD0707  [5]
 LDCM0391  CL120 HCT 116 C592(0.88); C595(0.88); C781(0.99); C782(0.99)  LDD0708  [5]
 LDCM0392  CL121 HCT 116 C781(0.50); C1230(0.89); C986(1.01); C987(1.01)  LDD0709  [5]
 LDCM0393  CL122 HCT 116 C592(0.83); C595(0.83); C986(0.84); C987(0.84)  LDD0710  [5]
 LDCM0394  CL123 HCT 116 C592(0.83); C595(0.83); C781(0.91); C986(1.13)  LDD0711  [5]
 LDCM0395  CL124 HCT 116 C592(0.88); C595(0.88); C781(1.10); C1230(1.16)  LDD0712  [5]
 LDCM0396  CL125 HCT 116 C817(0.80); C820(0.80); C986(0.88); C987(0.88)  LDD0713  [5]
 LDCM0397  CL126 HCT 116 C817(0.78); C820(0.78); C1230(1.00); C986(1.08)  LDD0714  [5]
 LDCM0398  CL127 HCT 116 C817(0.79); C820(0.79); C986(0.97); C987(0.97)  LDD0715  [5]
 LDCM0399  CL128 HCT 116 C817(0.62); C820(0.62); C398(0.84); C986(1.01)  LDD0716  [5]
 LDCM0400  CL13 HCT 116 C592(0.83); C595(0.83); C817(0.85); C820(0.85)  LDD0717  [5]
 LDCM0401  CL14 HCT 116 C592(0.73); C595(0.73); C817(0.74); C820(0.74)  LDD0718  [5]
 LDCM0402  CL15 HCT 116 C817(0.87); C820(0.87); C592(1.03); C595(1.03)  LDD0719  [5]
 LDCM0403  CL16 HCT 116 C1230(1.05); C781(1.05); C782(1.05); C817(1.16)  LDD0720  [5]
 LDCM0404  CL17 HCT 116 C986(0.80); C987(0.80); C817(0.93); C820(0.93)  LDD0721  [5]
 LDCM0405  CL18 HCT 116 C986(0.75); C987(0.75); C1230(0.97); C817(1.45)  LDD0722  [5]
 LDCM0406  CL19 HCT 116 C986(0.85); C987(0.85); C1230(0.97); C817(0.98)  LDD0723  [5]
 LDCM0407  CL2 HCT 116 C1230(0.84); C592(0.86); C595(0.86); C817(0.87)  LDD0724  [5]
 LDCM0408  CL20 HCT 116 C592(0.62); C595(0.62); C817(0.89); C820(0.89)  LDD0725  [5]
 LDCM0409  CL21 HCT 116 C592(0.73); C595(0.73); C986(0.79); C987(0.79)  LDD0726  [5]
 LDCM0410  CL22 HCT 116 C592(0.72); C595(0.72); C986(1.04); C987(1.04)  LDD0727  [5]
 LDCM0411  CL23 HCT 116 C986(0.59); C987(0.59); C592(0.67); C595(0.67)  LDD0728  [5]
 LDCM0412  CL24 HCT 116 C592(0.63); C595(0.63); C817(0.94); C820(0.94)  LDD0729  [5]
 LDCM0413  CL25 HCT 116 C1230(1.23); C397(1.77); C398(1.77); C592(0.64)  LDD0730  [5]
 LDCM0414  CL26 HCT 116 C1230(1.07); C397(1.78); C398(1.78); C592(0.84)  LDD0731  [5]
 LDCM0415  CL27 HCT 116 C1230(1.05); C397(2.79); C398(2.79); C592(0.75)  LDD0732  [5]
 LDCM0416  CL28 HCT 116 C1230(1.15); C397(1.90); C398(1.90); C592(0.82)  LDD0733  [5]
 LDCM0417  CL29 HCT 116 C1230(1.18); C397(1.64); C398(1.64); C592(0.74)  LDD0734  [5]
 LDCM0418  CL3 HCT 116 C1230(0.85); C592(0.87); C595(0.87); C817(0.84)  LDD0735  [5]
 LDCM0419  CL30 HCT 116 C1230(0.99); C397(2.14); C398(2.14); C592(0.98)  LDD0736  [5]
 LDCM0420  CL31 HCT 116 C1230(0.98); C547(0.90); C592(0.84); C595(0.84)  LDD0737  [5]
 LDCM0421  CL32 HCT 116 C1230(1.11); C547(0.89); C592(1.25); C595(1.25)  LDD0738  [5]
 LDCM0422  CL33 HCT 116 C1230(0.88); C547(1.00); C592(0.94); C595(0.94)  LDD0739  [5]
 LDCM0423  CL34 HCT 116 C1230(1.16); C547(1.06); C592(1.05); C595(1.05)  LDD0740  [5]
 LDCM0424  CL35 HCT 116 C1230(1.16); C547(1.17); C592(0.70); C595(0.70)  LDD0741  [5]
 LDCM0425  CL36 HCT 116 C1230(1.08); C547(1.01); C592(0.64); C595(0.64)  LDD0742  [5]
 LDCM0426  CL37 HCT 116 C1230(1.11); C547(1.29); C592(0.56); C595(0.56)  LDD0743  [5]
 LDCM0428  CL39 HCT 116 C1230(1.07); C547(0.86); C592(0.57); C595(0.57)  LDD0745  [5]
 LDCM0429  CL4 HCT 116 C1230(0.90); C592(0.76); C595(0.76); C817(0.87)  LDD0746  [5]
 LDCM0430  CL40 HCT 116 C1230(1.03); C547(1.02); C592(0.60); C595(0.60)  LDD0747  [5]
 LDCM0431  CL41 HCT 116 C1230(1.06); C547(0.94); C592(0.56); C595(0.56)  LDD0748  [5]
 LDCM0432  CL42 HCT 116 C1230(1.49); C547(1.01); C592(0.76); C595(0.76)  LDD0749  [5]
 LDCM0433  CL43 HCT 116 C1230(1.26); C547(0.74); C592(0.72); C595(0.72)  LDD0750  [5]
 LDCM0434  CL44 HCT 116 C1230(1.31); C547(0.85); C592(0.86); C595(0.86)  LDD0751  [5]
 LDCM0435  CL45 HCT 116 C1230(1.42); C547(1.01); C592(0.81); C595(0.81)  LDD0752  [5]
 LDCM0436  CL46 HCT 116 C1230(0.82); C1267(0.82); C592(0.82); C595(0.82)  LDD0753  [5]
 LDCM0437  CL47 HCT 116 C1230(0.83); C1267(0.87); C592(0.87); C595(0.87)  LDD0754  [5]
 LDCM0438  CL48 HCT 116 C1230(0.85); C1267(0.84); C592(0.91); C595(0.91)  LDD0755  [5]
 LDCM0439  CL49 HCT 116 C1230(0.86); C1267(0.93); C592(0.68); C595(0.68)  LDD0756  [5]
 LDCM0440  CL5 HCT 116 C1230(0.95); C592(0.82); C595(0.82); C817(0.79)  LDD0757  [5]
 LDCM0441  CL50 HCT 116 C1230(0.78); C1267(0.84); C592(0.80); C595(0.80)  LDD0758  [5]
 LDCM0442  CL51 HCT 116 C1230(0.78); C1267(0.93); C592(0.76); C595(0.76)  LDD0759  [5]
 LDCM0443  CL52 HCT 116 C1230(0.82); C1267(0.86); C592(0.75); C595(0.75)  LDD0760  [5]
 LDCM0444  CL53 HCT 116 C1230(0.76); C1267(0.90); C592(0.75); C595(0.75)  LDD0761  [5]
 LDCM0445  CL54 HCT 116 C1230(0.80); C1267(0.78); C592(0.83); C595(0.83)  LDD0762  [5]
 LDCM0446  CL55 HCT 116 C1230(0.71); C1267(0.85); C592(0.78); C595(0.78)  LDD0763  [5]
 LDCM0447  CL56 HCT 116 C1230(0.89); C1267(0.85); C592(0.75); C595(0.75)  LDD0764  [5]
 LDCM0448  CL57 HCT 116 C1230(0.74); C1267(0.79); C592(0.84); C595(0.84)  LDD0765  [5]
 LDCM0449  CL58 HCT 116 C1230(0.81); C1267(0.84); C592(1.05); C595(1.05)  LDD0766  [5]
 LDCM0450  CL59 HCT 116 C1230(0.91); C1267(0.93); C592(0.85); C595(0.85)  LDD0767  [5]
 LDCM0451  CL6 HCT 116 C1230(1.01); C592(1.41); C595(1.41); C817(1.07)  LDD0768  [5]
 LDCM0452  CL60 HCT 116 C1230(0.84); C1267(0.85); C592(0.83); C595(0.83)  LDD0769  [5]
 LDCM0453  CL61 HCT 116 C1230(0.96); C547(1.14); C592(0.86); C595(0.86)  LDD0770  [5]
 LDCM0454  CL62 HCT 116 C1230(1.04); C547(0.84); C592(0.97); C595(0.97)  LDD0771  [5]
 LDCM0455  CL63 HCT 116 C1230(1.00); C547(1.16); C592(1.04); C595(1.04)  LDD0772  [5]
 LDCM0456  CL64 HCT 116 C1230(1.08); C547(0.94); C592(0.72); C595(0.72)  LDD0773  [5]
 LDCM0457  CL65 HCT 116 C1230(0.93); C547(0.97); C592(1.26); C595(1.26)  LDD0774  [5]
 LDCM0458  CL66 HCT 116 C1230(1.20); C547(0.93); C592(0.99); C595(0.99)  LDD0775  [5]
 LDCM0459  CL67 HCT 116 C1230(1.12); C547(0.82); C592(0.89); C595(0.89)  LDD0776  [5]
 LDCM0460  CL68 HCT 116 C1230(0.91); C547(1.13); C592(1.18); C595(1.18)  LDD0777  [5]
 LDCM0461  CL69 HCT 116 C1230(1.04); C547(0.98); C592(1.39); C595(1.39)  LDD0778  [5]
 LDCM0462  CL7 HCT 116 C1230(1.20); C592(0.84); C595(0.84); C817(0.88)  LDD0779  [5]
 LDCM0463  CL70 HCT 116 C1230(0.96); C547(0.89); C592(1.11); C595(1.11)  LDD0780  [5]
 LDCM0464  CL71 HCT 116 C1230(1.01); C547(1.09); C592(0.98); C595(0.98)  LDD0781  [5]
 LDCM0465  CL72 HCT 116 C1230(0.92); C547(1.11); C592(1.02); C595(1.02)  LDD0782  [5]
 LDCM0466  CL73 HCT 116 C1230(1.03); C547(1.05); C592(0.88); C595(0.88)  LDD0783  [5]
 LDCM0467  CL74 HCT 116 C1230(1.01); C547(1.04); C592(0.85); C595(0.85)  LDD0784  [5]
 LDCM0469  CL76 HCT 116 C1230(0.97); C547(1.17); C592(1.23); C595(1.23)  LDD0786  [5]
 LDCM0470  CL77 HCT 116 C1230(0.88); C547(2.37); C592(0.71); C595(0.71)  LDD0787  [5]
 LDCM0471  CL78 HCT 116 C1230(0.97); C547(0.97); C592(0.68); C595(0.68)  LDD0788  [5]
 LDCM0472  CL79 HCT 116 C1230(1.14); C547(1.19); C592(0.58); C595(0.58)  LDD0789  [5]
 LDCM0473  CL8 HCT 116 C1230(1.31); C592(0.59); C595(0.59); C817(0.73)  LDD0790  [5]
 LDCM0474  CL80 HCT 116 C1230(1.08); C547(1.15); C592(1.09); C595(1.09)  LDD0791  [5]
 LDCM0475  CL81 HCT 116 C1230(1.09); C547(1.01); C592(0.76); C595(0.76)  LDD0792  [5]
 LDCM0476  CL82 HCT 116 C1230(1.31); C547(0.92); C592(0.72); C595(0.72)  LDD0793  [5]
 LDCM0477  CL83 HCT 116 C1230(1.25); C547(0.91); C592(0.59); C595(0.59)  LDD0794  [5]
 LDCM0478  CL84 HCT 116 C1230(1.49); C547(1.22); C592(0.67); C595(0.67)  LDD0795  [5]
 LDCM0479  CL85 HCT 116 C1230(1.05); C547(1.01); C592(0.68); C595(0.68)  LDD0796  [5]
 LDCM0480  CL86 HCT 116 C1230(1.03); C547(1.13); C592(0.73); C595(0.73)  LDD0797  [5]
 LDCM0481  CL87 HCT 116 C1230(1.11); C547(1.03); C592(0.70); C595(0.70)  LDD0798  [5]
 LDCM0482  CL88 HCT 116 C1230(1.23); C547(1.17); C592(0.65); C595(0.65)  LDD0799  [5]
 LDCM0483  CL89 HCT 116 C1230(1.59); C547(0.88); C592(0.86); C595(0.86)  LDD0800  [5]
 LDCM0484  CL9 HCT 116 C1230(1.03); C592(0.70); C595(0.70); C817(0.79)  LDD0801  [5]
 LDCM0485  CL90 HCT 116 C1230(0.96); C547(1.16); C592(0.87); C595(0.87)  LDD0802  [5]
 LDCM0486  CL91 HCT 116 C1230(1.04); C1267(0.84); C592(0.80); C595(0.80)  LDD0803  [5]
 LDCM0487  CL92 HCT 116 C1230(1.07); C1267(0.84); C592(0.96); C595(0.96)  LDD0804  [5]
 LDCM0488  CL93 HCT 116 C1230(1.09); C1267(0.82); C592(1.17); C595(1.17)  LDD0805  [5]
 LDCM0489  CL94 HCT 116 C1230(1.10); C1267(0.85); C592(0.85); C595(0.85)  LDD0806  [5]
 LDCM0490  CL95 HCT 116 C1230(1.00); C1267(0.83); C592(0.80); C595(0.80)  LDD0807  [5]
 LDCM0491  CL96 HCT 116 C1230(1.00); C1267(0.80); C592(0.99); C595(0.99)  LDD0808  [5]
 LDCM0492  CL97 HCT 116 C1230(1.03); C1267(0.84); C592(1.04); C595(1.04)  LDD0809  [5]
 LDCM0493  CL98 HCT 116 C1230(1.08); C1267(0.92); C592(0.79); C595(0.79)  LDD0810  [5]
 LDCM0494  CL99 HCT 116 C1230(1.15); C1267(0.83); C592(0.86); C595(0.86)  LDD0811  [5]
 LDCM0495  E2913 HEK-293T C1230(1.03); C1257(0.99); C547(0.87); C395(0.88)  LDD1698  [14]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C1219(2.52); C547(1.20)  LDD1702  [2]
 LDCM0468  Fragment33 HCT 116 C1230(0.97); C547(0.82); C592(1.11); C595(1.11)  LDD0785  [5]
 LDCM0427  Fragment51 HCT 116 C1230(1.25); C547(1.48); C592(0.74); C595(0.74)  LDD0744  [5]
 LDCM0022  KB02 HCT 116 C1230(2.29); C395(1.86); C398(1.86); C397(1.80)  LDD0080  [5]
 LDCM0023  KB03 HCT 116 C1230(3.03); C395(1.60); C398(1.60); C397(1.15)  LDD0081  [5]
 LDCM0024  KB05 HCT 116 C1230(2.35); C395(1.71); C398(1.71); C397(1.43)  LDD0082  [5]
 LDCM0109  NEM HeLa N.A.  LDD0227  [4]
 LDCM0497  Nucleophilic fragment 11b MDA-MB-231 C782(0.81)  LDD2090  [2]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C1267(0.70); C782(0.52)  LDD2127  [2]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C1219(2.35)  LDD2146  [2]
 LDCM0021  THZ1 HCT 116 C395(1.50); C397(1.50); C398(1.50); C1267(1.01)  LDD2173  [5]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 10 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Anterior gradient protein 2 homolog (AGR2) AGR family O95994
Diamine oxidase [copper-containing] (AOC1) Copper/topaquinone oxidase family P19801
Probable E3 ubiquitin-protein ligase DTX2 (DTX2) Deltex family Q86UW9
Eukaryotic translation initiation factor 3 subunit F (EIF3F) EIF-3 subunit F family O00303
L-fucose kinase (FCSK) GHMP kinase family Q8N0W3
Inactive glycosyltransferase 25 family member 3 (CERCAM) Glycosyltransferase 25 family Q5T4B2
Inactive Ufm1-specific protease 1 (UFSP1) Peptidase C78 family Q6NVU6
Unconventional myosin-Ib (MYO1B) Myosin family O43795
V-type proton ATPase 116 kDa subunit a 3 (TCIRG1) V-ATPase 116 kDa subunit family Q13488
Bifunctional peptidase and (3S)-lysyl hydroxylase JMJD7 (JMJD7) . P0C870
Transcription factor
Click To Hide/Show 18 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Protein FosB (FOSB) BZIP family P53539
Zinc finger protein 143 (ZNF143) GLI C2H2-type zinc-finger protein family P52747
Vascular endothelial zinc finger 1 (VEZF1) Krueppel C2H2-type zinc-finger protein family Q14119
Zinc finger and BTB domain-containing protein 24 (ZBTB24) Krueppel C2H2-type zinc-finger protein family O43167
Zinc finger protein 710 (ZNF710) Krueppel C2H2-type zinc-finger protein family Q8N1W2
Zinc finger protein 76 (ZNF76) Krueppel C2H2-type zinc-finger protein family P36508
Nuclear transcription factor Y subunit alpha (NFYA) NFYA/HAP2 subunit family P23511
Nuclear respiratory factor 1 (NRF1) NRF1/Ewg family Q16656
Cone-rod homeobox protein (CRX) Paired homeobox family O43186
POU domain, class 2, transcription factor 1 (POU2F1) POU transcription factor family P14859
POU domain class 2-associating factor 1 (POU2AF1) POU2AF family Q16633
Transcription factor Sp1 (SP1) Sp1 C2H2-type zinc-finger protein family P08047
Transcription factor Sp3 (SP3) Sp1 C2H2-type zinc-finger protein family Q02447
Transcription factor Sp4 (SP4) Sp1 C2H2-type zinc-finger protein family Q02446
Zinc finger protein ZXDC (ZXDC) ZXD family Q2QGD7
Glucocorticoid modulatory element-binding protein 2 (GMEB2) . Q9UKD1
T-box transcription factor TBX19 (TBX19) . O60806
Transcriptional regulator QRICH1 (QRICH1) . Q2TAL8
Other
Click To Hide/Show 30 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Ataxin-1 (ATXN1) ATXN1 family P54253
Protein BANP (BANP) BANP/SMAR1 family Q8N9N5
Lipopolysaccharide-induced tumor necrosis factor-alpha factor (LITAF) CDIP1/LITAF family Q99732
Keratin-associated protein 3-2 (KRTAP3-2) KRTAP type 3 family Q9BYR7
Keratin-associated protein 6-2 (KRTAP6-2) KRTAP type 6 family Q3LI66
Keratin-associated protein 8-1 (KRTAP8-1) KRTAP type 8 family Q8IUC2
Odontogenic ameloblast-associated protein (ODAM) ODAM family A1E959
Perilipin-2 (PLIN2) Perilipin family Q99541
Prefoldin subunit 5 (PFDN5) Prefoldin subunit alpha family Q99471
Proline-rich protein 20C (PRR20C) PRR20 family P86479
Proline-rich protein 20D (PRR20D) PRR20 family P86480
Heat shock protein beta-2 (HSPB2) Small heat shock protein (HSP20) family Q16082
APOBEC1 complementation factor (A1CF) . Q9NQ94
Chromobox protein homolog 5 (CBX5) . P45973
DAZ-associated protein 2 (DAZAP2) . Q15038
Disabled homolog 1 (DAB1) . O75553
EP300-interacting inhibitor of differentiation 2B (EID2B) . Q96D98
Four and a half LIM domains protein 2 (FHL2) . Q14192
GA-binding protein subunit beta-1 (GABPB1) . Q06547
Heat shock factor 2-binding protein (HSF2BP) . O75031
Hepatocyte growth factor-regulated tyrosine kinase substrate (HGS) . O14964
Kelch domain-containing protein 7B (KLHDC7B) . Q96G42
Kelch-like protein 26 (KLHL26) . Q53HC5
NHL-repeat-containing protein 4 (NHLRC4) . P0CG21
Nicolin-1 (NICN1) . Q9BSH3
Pleckstrin homology domain-containing family B member 2 (PLEKHB2) . Q96CS7
RNA-binding protein with multiple splicing (RBPMS) . Q93062
Saitohin (STH) . Q8IWL8
Spermatogenesis-associated protein 12 (SPATA12) . Q7Z6I5
Uncharacterized protein C10orf55 (C10orf55) . Q5SWW7

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
3 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
4 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
5 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
6 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
7 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
8 SP3-Enabled Rapid and High Coverage Chemoproteomic Identification of Cell-State-Dependent Redox-Sensitive Cysteines. Mol Cell Proteomics. 2022 Apr;21(4):100218. doi: 10.1016/j.mcpro.2022.100218. Epub 2022 Feb 25.
Mass spectrometry data entry: PXD029500 , PXD031647
9 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
10 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
11 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
12 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
13 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
14 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402